Ignite Creation Date:
2025-12-26 @ 10:57 AM
Ignite Modification Date:
2026-03-03 @ 6:47 PM
Study NCT ID:
NCT00113308
Status:
COMPLETED
Last Update Posted:
2017-03-14
First Post:
2005-06-07
Is NOT Gene Therapy:
True
Has Adverse Events:
False
Brief Title:
COX-2 Inhibitor Study In Patients With Rheumatoid Arthritis
Sponsor:
Organization:
Raw JSON
{'hasResults': False, 'derivedSection': {'miscInfoModule': {'versionHolder': '2025-12-24', 'removedCountries': ['Czechia', 'Estonia', 'Lithuania', 'Pakistan', 'Slovakia', 'Taiwan'], 'submissionTracking': {'submissionInfos': [{'releaseDate': '2017-09-06', 'unreleaseDate': '2018-08-15'}], 'estimatedResultsFirstSubmitDate': '2017-09-06'}}, 'conditionBrowseModule': {'meshes': [{'id': 'D001172', 'term': 'Arthritis, Rheumatoid'}], 'ancestors': [{'id': 'D001168', 'term': 'Arthritis'}, {'id': 'D007592', 'term': 'Joint Diseases'}, {'id': 'D009140', 'term': 'Musculoskeletal Diseases'}, {'id': 'D012216', 'term': 'Rheumatic Diseases'}, {'id': 'D003240', 'term': 'Connective Tissue Diseases'}, {'id': 'D017437', 'term': 'Skin and Connective Tissue Diseases'}, {'id': 'D001327', 'term': 'Autoimmune Diseases'}, {'id': 'D007154', 'term': 'Immune System Diseases'}]}, 'interventionBrowseModule': {'meshes': [{'id': 'C469818', 'term': 'GW406381X'}]}}, 'protocolSection': {'designModule': {'phases': ['PHASE3'], 'studyType': 'INTERVENTIONAL', 'designInfo': {'allocation': 'RANDOMIZED', 'maskingInfo': {'masking': 'DOUBLE', 'whoMasked': ['PARTICIPANT', 'INVESTIGATOR']}, 'primaryPurpose': 'TREATMENT', 'interventionModel': 'SINGLE_GROUP'}, 'enrollmentInfo': {'type': 'ACTUAL', 'count': 2208}}, 'statusModule': {'overallStatus': 'COMPLETED', 'startDateStruct': {'date': '2005-06'}, 'statusVerifiedDate': '2017-03', 'completionDateStruct': {'date': '2006-09', 'type': 'ACTUAL'}, 'lastUpdateSubmitDate': '2017-03-13', 'studyFirstSubmitDate': '2005-06-07', 'studyFirstSubmitQcDate': '2005-06-07', 'lastUpdatePostDateStruct': {'date': '2017-03-14', 'type': 'ACTUAL'}, 'studyFirstPostDateStruct': {'date': '2005-06-08', 'type': 'ESTIMATED'}, 'primaryCompletionDateStruct': {'date': '2006-09', 'type': 'ACTUAL'}}, 'outcomesModule': {'primaryOutcomes': [{'measure': 'Percentage of American College of Rheumatology (ACR)20 Responders at Week 12', 'timeFrame': 'Week 12'}], 'secondaryOutcomes': [{'measure': 'Change from baseline to each scheduled visit in tender/painful joint count (68 joint panel)', 'timeFrame': 'Baseline and Week 12'}, {'measure': 'Change from baseline to each scheduled visit in swollen joint count (66 joint panel)', 'timeFrame': 'Baseline and Week 12'}, {'measure': "Change from baseline to each scheduled visit in patient's pain assessment (VAS)", 'timeFrame': 'Baseline and Week 12'}, {'measure': "Change from baseline to each scheduled visit in physician's global assessment of arthritis condition", 'timeFrame': 'Baseline and Week 12'}, {'measure': "Change from baseline to each scheduled visit in patient's global assessment of arthritis condition", 'timeFrame': 'Baseline and Week 12'}, {'measure': 'Change from baseline to each scheduled visit in functional disability index (HAQ)', 'timeFrame': 'Baseline and Week 12'}, {'measure': 'Change between baseline and end of treatment (or early withdrawal) in the Short Form - McGill Pain Questionnaire (SF-MPQ)', 'timeFrame': 'Baseline and Up to Week 12'}, {'measure': 'Change from baseline to each scheduled visit in C-reactive protein (CRP)', 'timeFrame': 'Baseline and up to Week 12'}, {'measure': 'Number of participants withdrawing from the study due to lack of efficacy', 'timeFrame': 'Week 12'}, {'measure': 'Number of participants who received supplementary analgesic therapy', 'timeFrame': 'Week 12'}, {'measure': 'Changes from pretreatment to on treatment and post-treatment follow-up in vital signs- systolic blood pressure (SBP) and diastolic blood pressure (DBP)', 'timeFrame': 'Baseline and up to Week 12'}, {'measure': 'Changes from pretreatment to on treatment and post-treatment follow-up in vital signs- heart rate (HR)', 'timeFrame': 'Baseline and up to Week 12'}, {'measure': 'Changes from pretreatment to on treatment and post-treatment follow-up in weight', 'timeFrame': 'Baseline and Week 12'}, {'measure': 'Number of participants with change in BMI of potential clinical concern', 'timeFrame': 'Week 4, 4, 8, 12 and foloow up'}, {'measure': 'Number of participants with change from baseline of pedal oedema (including diuretic use)', 'timeFrame': 'Baseline and up to Week 12'}, {'measure': 'Change from baseline in 12-lead electrocardiograms (ECGs)', 'timeFrame': 'Baseline and up to Week 12'}, {'measure': 'Change from baseline in clinical chemistry parameters: Albumin', 'timeFrame': 'Baseline and up to Week 12'}, {'measure': 'Change from baseline in clinical chemistry parameters: Alkaline Phosphatase, Alanine Amino Transferase, Aspartate Amino Transferase', 'timeFrame': 'Baseline and Up to Week 12'}, {'measure': 'Change from baseline in clinical chemistry parameters: Total Bilirubin', 'timeFrame': 'Baseline and up to Week 12'}, {'measure': 'Change from baseline in clinical chemistry parameters: Carbon Dioxide content /Bicarbonate, Glucose, Potassium, Sodium', 'timeFrame': 'Baseline and up to Week 12'}, {'measure': 'Change from baseline in clinical chemistry parameters: Creatinine', 'timeFrame': 'Baseline and up to Week 12'}, {'measure': 'Change from baseline in haematology parameters: Basophils, Eosinophils, Lymphocytes, Monocytes, Total Neutrophils, Platelet count, White Blood Cell count', 'timeFrame': 'Baseline and up to Week 12'}, {'measure': 'Change from baseline in haematology parameters: Hemoglobin', 'timeFrame': 'Baseline and up to Week 12'}, {'measure': 'Change from baseline in haematology parameters: Mean Corpuscle volume', 'timeFrame': 'Baseline and Up to Week 12'}, {'measure': 'Change from baseline in haematology parameters: Red Blood Cell count', 'timeFrame': 'Baseline and up to Week 12'}, {'measure': 'Urinalysis assessment', 'timeFrame': 'Up to Week 12'}, {'measure': 'Number of participants with adverse events (AEs) and serious adverse events (SAEs)', 'timeFrame': 'Upto Week 12'}, {'measure': 'Change in the Short Form-36 (SF-36v2) subscale scores between baseline and the end of treatment (or early withdrawal)', 'timeFrame': 'Baseline and Week 12'}, {'measure': 'Change in the Short Form-36 (SF-36v2) Physical component summary score and mental component summary score between baseline and the end of treatment (or early withdrawal)', 'timeFrame': 'Baseline and Week 12'}, {'measure': 'Psychometrically test and validate the amended Patient Satisfaction with Pain Medication questionnaire', 'timeFrame': 'Week 12'}, {'measure': 'Change between baseline and end of treatment (or early withdrawal) in the EuroQoL Questionnaire -5 Dimensions (EQ-5D) utility score, using European population utility tariff', 'timeFrame': 'Baseline and Week 12'}, {'measure': 'Change between baseline and end of treatment (or early withdrawal) in the fatigue/inertia factor of the Profile of Moods States Brief Form (POMS-B)', 'timeFrame': 'Baseline and Week 12'}]}, 'oversightModule': {'oversightHasDmc': False}, 'conditionsModule': {'keywords': ['Rheumatoid Arthritis', 'COX-2 Inhibitor'], 'conditions': ['Arthritis, Rheumatoid']}, 'descriptionModule': {'briefSummary': 'This study is being conducted to find out if an investigational drug called GW406381 can help people with rheumatoid arthritis.'}, 'eligibilityModule': {'sex': 'ALL', 'stdAges': ['ADULT', 'OLDER_ADULT'], 'minimumAge': '18 Years', 'healthyVolunteers': False, 'eligibilityCriteria': 'Inclusion criteria:\n\n* Rheumatoid arthritis (RA) for at least 12 months.\n* Required a non-steroidal anti-inflammatory drug (NSAID) or COX-2 inhibitor for RA for at least 5 out of 7 days of each week for the 4 weeks prior to screening.\n\nExclusion criteria:\n\n* Any history of cardiovascular disease (e.g., heart attack, stroke, congestive heart failure, uncontrolled high blood pressure), documented peripheral arterial insufficiency and symptomatic, clinically significant claudication, or who have a history of peripheral arterial embolism.\n* Have an active stomach ulcer or history of any stomach tear or bleeding.'}, 'identificationModule': {'nctId': 'NCT00113308', 'briefTitle': 'COX-2 Inhibitor Study In Patients With Rheumatoid Arthritis', 'organization': {'class': 'INDUSTRY', 'fullName': 'GlaxoSmithKline'}, 'officialTitle': 'A Phase III, 12-Week, Multicentre, Double-Blind, Randomised, Placebo- and Active Comparator-Controlled, Parallel Group Study to Investigate the Efficacy and Safety of GW406381, 5mg, 10mg, 25mg, and 50mg Administered Orally Once Daily, in Adults With Rheumatoid Arthritis', 'orgStudyIdInfo': {'id': 'CXA30009'}}, 'armsInterventionsModule': {'interventions': [{'name': 'GW406381', 'type': 'DRUG'}]}, 'contactsLocationsModule': {'locations': [{'zip': '36207', 'city': 'Anniston', 'state': 'Alabama', 'country': 'United States', 'facility': 'GSK Investigational Site', 'geoPoint': {'lat': 33.65983, 'lon': -85.83163}}, {'zip': '35205', 'city': 'Birmingham', 'state': 'Alabama', 'country': 'United States', 'facility': 'GSK Investigational Site', 'geoPoint': {'lat': 33.52066, 'lon': -86.80249}}, {'zip': '35215', 'city': 'Birmingham', 'state': 'Alabama', 'country': 'United States', 'facility': 'GSK Investigational Site', 'geoPoint': {'lat': 33.52066, 'lon': -86.80249}}, {'zip': '35801', 'city': 'Huntsville', 'state': 'Alabama', 'country': 'United States', 'facility': 'GSK Investigational Site', 'geoPoint': {'lat': 34.7304, 'lon': -86.58594}}, {'zip': '36106', 'city': 'Montgomery', 'state': 'Alabama', 'country': 'United States', 'facility': 'GSK Investigational Site', 'geoPoint': {'lat': 32.36681, 'lon': -86.29997}}, {'zip': '36111', 'city': 'Montgomery', 'state': 'Alabama', 'country': 'United States', 'facility': 'GSK Investigational Site', 'geoPoint': {'lat': 32.36681, 'lon': -86.29997}}, {'zip': '85308', 'city': 'Glendale', 'state': 'Arizona', 'country': 'United States', 'facility': 'GSK Investigational Site', 'geoPoint': {'lat': 33.53865, 'lon': -112.18599}}, {'zip': '85251', 'city': 'Scottsdale', 'state': 'Arizona', 'country': 'United States', 'facility': 'GSK Investigational Site', 'geoPoint': {'lat': 33.50921, 'lon': -111.89903}}, {'zip': '85704', 'city': 'Tucson', 'state': 'Arizona', 'country': 'United States', 'facility': 'GSK Investigational Site', 'geoPoint': {'lat': 32.22174, 'lon': -110.92648}}, {'zip': '85719', 'city': 'Tucson', 'state': 'Arizona', 'country': 'United States', 'facility': 'GSK Investigational Site', 'geoPoint': {'lat': 32.22174, 'lon': -110.92648}}, {'zip': '92801', 'city': 'Anaheim', 'state': 'California', 'country': 'United States', 'facility': 'GSK Investigational Site', 'geoPoint': {'lat': 33.83529, 'lon': -117.9145}}, {'zip': '92260', 'city': 'Palm Desert', 'state': 'California', 'country': 'United States', 'facility': 'GSK Investigational Site', 'geoPoint': {'lat': 33.72255, 'lon': -116.37697}}, {'zip': '92103-6204', 'city': 'San Diego', 'state': 'California', 'country': 'United States', 'facility': 'GSK Investigational Site', 'geoPoint': {'lat': 32.71571, 'lon': -117.16472}}, {'zip': '92108', 'city': 'San Diego', 'state': 'California', 'country': 'United States', 'facility': 'GSK Investigational Site', 'geoPoint': {'lat': 32.71571, 'lon': -117.16472}}, {'zip': '92128', 'city': 'San Diego', 'state': 'California', 'country': 'United States', 'facility': 'GSK Investigational Site', 'geoPoint': {'lat': 32.71571, 'lon': -117.16472}}, {'zip': '90048', 'city': 'Santa Monica', 'state': 'California', 'country': 'United States', 'facility': 'GSK Investigational Site', 'geoPoint': {'lat': 34.01949, 'lon': -118.49138}}, {'zip': '91786', 'city': 'Upland', 'state': 'California', 'country': 'United States', 'facility': 'GSK Investigational Site', 'geoPoint': {'lat': 34.09751, 'lon': -117.64839}}, {'zip': '80909', 'city': 'Colorado Springs', 'state': 'Colorado', 'country': 'United States', 'facility': 'GSK Investigational Site', 'geoPoint': {'lat': 38.83388, 'lon': -104.82136}}, {'zip': '06606', 'city': 'Bridgeport', 'state': 'Connecticut', 'country': 'United States', 'facility': 'GSK Investigational Site', 'geoPoint': {'lat': 41.17923, 'lon': -73.18945}}, {'zip': '06810', 'city': 'Danbury', 'state': 'Connecticut', 'country': 'United States', 'facility': 'GSK Investigational Site', 'geoPoint': {'lat': 41.39482, 'lon': -73.45401}}, {'zip': '06518', 'city': 'Hamden', 'state': 'Connecticut', 'country': 'United States', 'facility': 'GSK Investigational Site', 'geoPoint': {'lat': 41.39593, 'lon': -72.89677}}, {'zip': '06611', 'city': 'Trumbull', 'state': 'Connecticut', 'country': 'United States', 'facility': 'GSK Investigational Site', 'geoPoint': {'lat': 41.24287, 'lon': -73.20067}}, {'zip': '33180', 'city': 'Aventura', 'state': 'Florida', 'country': 'United States', 'facility': 'GSK Investigational Site', 'geoPoint': {'lat': 25.95648, 'lon': -80.13921}}, {'zip': '32114', 'city': 'Daytona Beach', 'state': 'Florida', 'country': 'United States', 'facility': 'GSK Investigational Site', 'geoPoint': {'lat': 29.21081, 'lon': -81.02283}}, {'zip': '32720', 'city': 'DeLand', 'state': 'Florida', 'country': 'United States', 'facility': 'GSK Investigational Site', 'geoPoint': {'lat': 29.02832, 'lon': -81.30312}}, {'zip': '34698', 'city': 'Dunedin', 'state': 'Florida', 'country': 'United States', 'facility': 'GSK Investigational Site', 'geoPoint': {'lat': 28.0199, 'lon': -82.77323}}, {'zip': '33773', 'city': 'Largo', 'state': 'Florida', 'country': 'United States', 'facility': 'GSK Investigational Site', 'geoPoint': {'lat': 27.90979, 'lon': -82.78842}}, {'zip': '33156', 'city': 'Miami', 'state': 'Florida', 'country': 'United States', 'facility': 'GSK Investigational Site', 'geoPoint': {'lat': 25.77427, 'lon': -80.19366}}, {'zip': '33173', 'city': 'Miami', 'state': 'Florida', 'country': 'United States', 'facility': 'GSK Investigational Site', 'geoPoint': {'lat': 25.77427, 'lon': -80.19366}}, {'zip': '34474', 'city': 'Ocala', 'state': 'Florida', 'country': 'United States', 'facility': 'GSK Investigational Site', 'geoPoint': {'lat': 29.1872, 'lon': -82.14009}}, {'zip': '32804', 'city': 'Orlando', 'state': 'Florida', 'country': 'United States', 'facility': 'GSK Investigational Site', 'geoPoint': {'lat': 28.53834, 'lon': -81.37924}}, {'zip': '32806', 'city': 'Orlando', 'state': 'Florida', 'country': 'United States', 'facility': 'GSK Investigational Site', 'geoPoint': {'lat': 28.53834, 'lon': -81.37924}}, {'zip': '34684', 'city': 'Palm Harbor', 'state': 'Florida', 'country': 'United States', 'facility': 'GSK Investigational Site', 'geoPoint': {'lat': 28.07807, 'lon': -82.76371}}, {'zip': '32127', 'city': 'Port Orange', 'state': 'Florida', 'country': 'United States', 'facility': 'GSK Investigational Site', 'geoPoint': {'lat': 29.13832, 'lon': -80.99561}}, {'zip': '34996', 'city': 'Stuart', 'state': 'Florida', 'country': 'United States', 'facility': 'GSK Investigational Site', 'geoPoint': {'lat': 27.19755, 'lon': -80.25283}}, {'zip': '33614', 'city': 'Tampa', 'state': 'Florida', 'country': 'United States', 'facility': 'GSK Investigational Site', 'geoPoint': {'lat': 27.94752, 'lon': -82.45843}}, {'zip': '34655', 'city': 'Trinity', 'state': 'Florida', 'country': 'United States', 'facility': 'GSK Investigational Site', 'geoPoint': {'lat': 28.18085, 'lon': -82.68177}}, {'zip': '33409', 'city': 'West Palm Beach', 'state': 'Florida', 'country': 'United States', 'facility': 'GSK Investigational Site', 'geoPoint': {'lat': 26.71534, 'lon': -80.05337}}, {'zip': '33540', 'city': 'Zephyrhills', 'state': 'Florida', 'country': 'United States', 'facility': 'GSK Investigational Site', 'geoPoint': {'lat': 28.23362, 'lon': -82.18119}}, {'zip': '30342', 'city': 'Atlanta', 'state': 'Georgia', 'country': 'United States', 'facility': 'GSK Investigational Site', 'geoPoint': {'lat': 33.749, 'lon': -84.38798}}, {'zip': '30501', 'city': 'Gainsville', 'state': 'Georgia', 'country': 'United States', 'facility': 'GSK Investigational Site'}, {'zip': '30075', 'city': 'Roswell', 'state': 'Georgia', 'country': 'United States', 'facility': 'GSK Investigational Site', 'geoPoint': {'lat': 34.02316, 'lon': -84.36159}}, {'zip': '30189', 'city': 'Woodstock', 'state': 'Georgia', 'country': 'United States', 'facility': 'GSK Investigational Site', 'geoPoint': {'lat': 34.10149, 'lon': -84.51938}}, {'zip': '83401', 'city': 'Idaho Falls', 'state': 'Idaho', 'country': 'United States', 'facility': 'GSK Investigational Site', 'geoPoint': {'lat': 43.46658, 'lon': -112.03414}}, {'zip': '60201', 'city': 'Evanston', 'state': 'Illinois', 'country': 'United States', 'facility': 'GSK Investigational Site', 'geoPoint': {'lat': 42.04114, 'lon': -87.69006}}, {'zip': '60053', 'city': 'Morton Grove', 'state': 'Illinois', 'country': 'United States', 'facility': 'GSK Investigational Site', 'geoPoint': {'lat': 42.04059, 'lon': -87.78256}}, {'zip': '62704', 'city': 'Springfield', 'state': 'Illinois', 'country': 'United States', 'facility': 'GSK Investigational Site', 'geoPoint': {'lat': 39.80172, 'lon': -89.64371}}, {'zip': '47714', 'city': 'Evansville', 'state': 'Indiana', 'country': 'United States', 'facility': 'GSK Investigational Site', 'geoPoint': {'lat': 37.97476, 'lon': -87.55585}}, {'zip': '46202', 'city': 'Indianapolis', 'state': 'Indiana', 'country': 'United States', 'facility': 'GSK Investigational Site', 'geoPoint': {'lat': 39.76838, 'lon': -86.15804}}, {'zip': '46227', 'city': 'Indianapolis', 'state': 'Indiana', 'country': 'United States', 'facility': 'GSK Investigational Site', 'geoPoint': {'lat': 39.76838, 'lon': -86.15804}}, {'zip': '66206', 'city': 'Prairie Village', 'state': 'Kansas', 'country': 'United States', 'facility': 'GSK Investigational Site', 'geoPoint': {'lat': 38.99167, 'lon': -94.63357}}, {'zip': '67207', 'city': 'Wichita', 'state': 'Kansas', 'country': 'United States', 'facility': 'GSK Investigational Site', 'geoPoint': {'lat': 37.69224, 'lon': -97.33754}}, {'zip': '40202', 'city': 'Louisville', 'state': 'Kentucky', 'country': 'United States', 'facility': 'GSK Investigational Site', 'geoPoint': {'lat': 38.25424, 'lon': -85.75941}}, {'zip': '40207', 'city': 'Louisville', 'state': 'Kentucky', 'country': 'United States', 'facility': 'GSK Investigational Site', 'geoPoint': {'lat': 38.25424, 'lon': -85.75941}}, {'zip': '40213', 'city': 'Louisville', 'state': 'Kentucky', 'country': 'United States', 'facility': 'GSK Investigational Site', 'geoPoint': {'lat': 38.25424, 'lon': -85.75941}}, {'zip': '70115', 'city': 'New Orleans', 'state': 'Louisiana', 'country': 'United States', 'facility': 'GSK Investigational Site', 'geoPoint': {'lat': 29.95465, 'lon': -90.07507}}, {'zip': '70458', 'city': 'Slidell', 'state': 'Louisiana', 'country': 'United States', 'facility': 'GSK Investigational Site', 'geoPoint': {'lat': 30.27519, 'lon': -89.78117}}, {'zip': '20902', 'city': 'Wheaton', 'state': 'Maryland', 'country': 'United States', 'facility': 'GSK Investigational Site', 'geoPoint': {'lat': 39.03983, 'lon': -77.05526}}, {'zip': '02720', 'city': 'Fall River', 'state': 'Massachusetts', 'country': 'United States', 'facility': 'GSK Investigational Site', 'geoPoint': {'lat': 41.70149, 'lon': -71.15505}}, {'zip': '01107', 'city': 'Springfield', 'state': 'Massachusetts', 'country': 'United States', 'facility': 'GSK Investigational Site', 'geoPoint': {'lat': 42.10148, 'lon': -72.58981}}, {'zip': '49048', 'city': 'Kalamazoo', 'state': 'Michigan', 'country': 'United States', 'facility': 'GSK Investigational Site', 'geoPoint': {'lat': 42.29171, 'lon': -85.58723}}, {'zip': '48910', 'city': 'Lansing', 'state': 'Michigan', 'country': 'United States', 'facility': 'GSK Investigational Site', 'geoPoint': {'lat': 42.73253, 'lon': -84.55553}}, {'zip': '63117', 'city': 'St Louis', 'state': 'Missouri', 'country': 'United States', 'facility': 'GSK Investigational Site', 'geoPoint': {'lat': 38.62727, 'lon': -90.19789}}, {'zip': '63141', 'city': 'St Louis', 'state': 'Missouri', 'country': 'United States', 'facility': 'GSK Investigational Site', 'geoPoint': {'lat': 38.62727, 'lon': -90.19789}}, {'zip': '89103', 'city': 'Las Vegas', 'state': 'Nevada', 'country': 'United States', 'facility': 'GSK Investigational Site', 'geoPoint': {'lat': 36.17497, 'lon': -115.13722}}, {'zip': '89106', 'city': 'Las Vegas', 'state': 'Nevada', 'country': 'United States', 'facility': 'GSK Investigational Site', 'geoPoint': {'lat': 36.17497, 'lon': -115.13722}}, {'zip': '89128', 'city': 'Las Vegas', 'state': 'Nevada', 'country': 'United States', 'facility': 'GSK Investigational Site', 'geoPoint': {'lat': 36.17497, 'lon': -115.13722}}, {'zip': '89502', 'city': 'Reno', 'state': 'Nevada', 'country': 'United States', 'facility': 'GSK Investigational Site', 'geoPoint': {'lat': 39.52963, 'lon': -119.8138}}, {'zip': '03820', 'city': 'Dover', 'state': 'New Hampshire', 'country': 'United States', 'facility': 'GSK Investigational Site', 'geoPoint': {'lat': 43.19786, 'lon': -70.87367}}, {'zip': '08009', 'city': 'Berlin', 'state': 'New Jersey', 'country': 'United States', 'facility': 'GSK Investigational Site', 'geoPoint': {'lat': 39.79123, 'lon': -74.92905}}, {'zip': '08619', 'city': 'Mercerville', 'state': 'New Jersey', 'country': 'United States', 'facility': 'GSK Investigational Site', 'geoPoint': {'lat': 40.23705, 'lon': -74.68655}}, {'zip': '13790', 'city': 'Johnson City', 'state': 'New York', 'country': 'United States', 'facility': 'GSK Investigational Site', 'geoPoint': {'lat': 42.11563, 'lon': -75.95881}}, {'zip': '12401', 'city': 'Kingston', 'state': 'New York', 'country': 'United States', 'facility': 'GSK Investigational Site', 'geoPoint': {'lat': 41.92704, 'lon': -73.99736}}, {'zip': '10024', 'city': 'New York', 'state': 'New York', 'country': 'United States', 'facility': 'GSK Investigational Site', 'geoPoint': {'lat': 40.71427, 'lon': -74.00597}}, {'zip': '11758', 'city': 'North Massapequa', 'state': 'New York', 'country': 'United States', 'facility': 'GSK Investigational Site', 'geoPoint': {'lat': 40.70093, 'lon': -73.46207}}, {'zip': '14618', 'city': 'Rochester', 'state': 'New York', 'country': 'United States', 'facility': 'GSK Investigational Site', 'geoPoint': {'lat': 43.15478, 'lon': -77.61556}}, {'zip': '28210', 'city': 'Charlotte', 'state': 'North Carolina', 'country': 'United States', 'facility': 'GSK Investigational Site', 'geoPoint': {'lat': 35.22709, 'lon': -80.84313}}, {'zip': '28054', 'city': 'Gastonia', 'state': 'North Carolina', 'country': 'United States', 'facility': 'GSK Investigational Site', 'geoPoint': {'lat': 35.26208, 'lon': -81.1873}}, {'zip': '28601', 'city': 'Hickory', 'state': 'North Carolina', 'country': 'United States', 'facility': 'GSK Investigational Site', 'geoPoint': {'lat': 35.73319, 'lon': -81.3412}}, {'zip': '28625', 'city': 'Statesville', 'state': 'North Carolina', 'country': 'United States', 'facility': 'GSK Investigational Site', 'geoPoint': {'lat': 35.78264, 'lon': -80.8873}}, {'zip': '44130', 'city': 'Cleveland', 'state': 'Ohio', 'country': 'United States', 'facility': 'GSK Investigational Site', 'geoPoint': {'lat': 41.4995, 'lon': -81.69541}}, {'zip': '43210', 'city': 'Columbus', 'state': 'Ohio', 'country': 'United States', 'facility': 'GSK Investigational Site', 'geoPoint': {'lat': 39.96118, 'lon': -82.99879}}, {'zip': '45219', 'city': 'Concinnati', 'state': 'Ohio', 'country': 'United States', 'facility': 'GSK Investigational Site'}, {'zip': '44143', 'city': 'Mayfield Village', 'state': 'Ohio', 'country': 'United States', 'facility': 'GSK Investigational Site'}, {'zip': '73112', 'city': 'Oklahoma City', 'state': 'Oklahoma', 'country': 'United States', 'facility': 'GSK Investigational Site', 'geoPoint': {'lat': 35.46756, 'lon': -97.51643}}, {'zip': '74104', 'city': 'Tulsa', 'state': 'Oklahoma', 'country': 'United States', 'facility': 'GSK Investigational Site', 'geoPoint': {'lat': 36.15398, 'lon': -95.99277}}, {'zip': '74135', 'city': 'Tulsa', 'state': 'Oklahoma', 'country': 'United States', 'facility': 'GSK Investigational Site', 'geoPoint': {'lat': 36.15398, 'lon': -95.99277}}, {'zip': '97504', 'city': 'Medford', 'state': 'Oregon', 'country': 'United States', 'facility': 'GSK Investigational Site', 'geoPoint': {'lat': 42.32652, 'lon': -122.87559}}, {'zip': '16635', 'city': 'Duncansville', 'state': 'Pennsylvania', 'country': 'United States', 'facility': 'GSK Investigational Site', 'geoPoint': {'lat': 40.42341, 'lon': -78.4339}}, {'zip': '19118', 'city': 'Philadelphia', 'state': 'Pennsylvania', 'country': 'United States', 'facility': 'GSK Investigational Site', 'geoPoint': {'lat': 39.95238, 'lon': -75.16362}}, {'zip': '19140', 'city': 'Philadelphia', 'state': 'Pennsylvania', 'country': 'United States', 'facility': 'GSK Investigational Site', 'geoPoint': {'lat': 39.95238, 'lon': -75.16362}}, {'zip': '19611', 'city': 'West Reading', 'state': 'Pennsylvania', 'country': 'United States', 'facility': 'GSK Investigational Site', 'geoPoint': {'lat': 40.3337, 'lon': -75.94743}}, {'zip': '29406', 'city': 'Charleston', 'state': 'South Carolina', 'country': 'United States', 'facility': 'GSK Investigational Site', 'geoPoint': {'lat': 32.77632, 'lon': -79.93275}}, {'zip': '29407', 'city': 'Charleston', 'state': 'South Carolina', 'country': 'United States', 'facility': 'GSK Investigational Site', 'geoPoint': {'lat': 32.77632, 'lon': -79.93275}}, {'zip': '29651', 'city': 'Greer', 'state': 'South Carolina', 'country': 'United States', 'facility': 'GSK Investigational Site', 'geoPoint': {'lat': 34.93873, 'lon': -82.22706}}, {'zip': '29924', 'city': 'Hampton', 'state': 'South Carolina', 'country': 'United States', 'facility': 'GSK Investigational Site', 'geoPoint': {'lat': 32.87794, 'lon': -81.12761}}, {'zip': '29576', 'city': 'Murrells Inlet', 'state': 'South Carolina', 'country': 'United States', 'facility': 'GSK Investigational Site', 'geoPoint': {'lat': 33.551, 'lon': -79.04143}}, {'zip': '38119', 'city': 'Memphis', 'state': 'Tennessee', 'country': 'United States', 'facility': 'GSK Investigational Site', 'geoPoint': {'lat': 35.14953, 'lon': -90.04898}}, {'zip': '78705', 'city': 'Austin', 'state': 'Texas', 'country': 'United States', 'facility': 'GSK Investigational Site', 'geoPoint': {'lat': 30.26715, 'lon': -97.74306}}, {'zip': '75231', 'city': 'Dallas', 'state': 'Texas', 'country': 'United States', 'facility': 'GSK Investigational Site', 'geoPoint': {'lat': 32.78306, 'lon': -96.80667}}, {'zip': '78229', 'city': 'San Antonio', 'state': 'Texas', 'country': 'United States', 'facility': 'GSK Investigational Site', 'geoPoint': {'lat': 29.42412, 'lon': -98.49363}}, {'zip': '78232', 'city': 'San Antonio', 'state': 'Texas', 'country': 'United States', 'facility': 'GSK Investigational Site', 'geoPoint': {'lat': 29.42412, 'lon': -98.49363}}, {'zip': '98201', 'city': 'Everett', 'state': 'Washington', 'country': 'United States', 'facility': 'GSK Investigational Site', 'geoPoint': {'lat': 47.97898, 'lon': -122.20208}}, {'zip': '98664', 'city': 'Vancouver', 'state': 'Washington', 'country': 'United States', 'facility': 'GSK Investigational Site', 'geoPoint': {'lat': 45.63873, 'lon': -122.66149}}, {'zip': '53404', 'city': 'Racine', 'state': 'Wisconsin', 'country': 'United States', 'facility': 'GSK Investigational Site', 'geoPoint': {'lat': 42.72613, 'lon': -87.78285}}, {'zip': '5000', 'city': 'Córdoba', 'state': 'Córdoba Province', 'country': 'Argentina', 'facility': 'GSK Investigational Site', 'geoPoint': {'lat': -31.40648, 'lon': -64.18853}}, {'city': 'Córdoba', 'state': 'Córdoba Province', 'country': 'Argentina', 'facility': 'GSK Investigational Site', 'geoPoint': {'lat': -31.40648, 'lon': -64.18853}}, {'zip': '2000', 'city': 'Rosario', 'state': 'Santa Fe Province', 'country': 'Argentina', 'facility': 'GSK Investigational Site', 'geoPoint': {'lat': -32.94682, 'lon': -60.63932}}, {'zip': '1013', 'city': 'Buenos Aires', 'country': 'Argentina', 'facility': 'GSK Investigational Site', 'geoPoint': {'lat': -34.61315, 'lon': -58.37723}}, {'zip': '1427', 'city': 'Buenos Aires', 'country': 'Argentina', 'facility': 'GSK Investigational Site', 'geoPoint': {'lat': -34.61315, 'lon': -58.37723}}, {'zip': 'C1121ABE', 'city': 'Buenos Aires', 'country': 'Argentina', 'facility': 'GSK Investigational Site', 'geoPoint': {'lat': -34.61315, 'lon': -58.37723}}, {'zip': 'C1128AAF', 'city': 'Buenos Aires', 'country': 'Argentina', 'facility': 'GSK Investigational Site', 'geoPoint': {'lat': -34.61315, 'lon': -58.37723}}, {'zip': 'C1426BOR', 'city': 'Buenos Aires', 'country': 'Argentina', 'facility': 'GSK Investigational Site', 'geoPoint': {'lat': -34.61315, 'lon': -58.37723}}, {'zip': '5000', 'city': 'Córdoba', 'country': 'Argentina', 'facility': 'GSK Investigational Site', 'geoPoint': {'lat': -31.40648, 'lon': -64.18853}}, {'zip': '1878', 'city': 'Quilmes', 'country': 'Argentina', 'facility': 'GSK Investigational Site', 'geoPoint': {'lat': -34.72065, 'lon': -58.25454}}, {'zip': '5400', 'city': 'San Juan', 'country': 'Argentina', 'facility': 'GSK Investigational Site', 'geoPoint': {'lat': -31.53726, 'lon': -68.52568}}, {'zip': '4000', 'city': 'San Miguel de Tucumán', 'country': 'Argentina', 'facility': 'GSK Investigational Site', 'geoPoint': {'lat': -26.81601, 'lon': -65.21051}}, {'zip': 'A-1021', 'city': 'Vienna', 'country': 'Austria', 'facility': 'GSK Investigational Site', 'geoPoint': {'lat': 48.20849, 'lon': 16.37208}}, {'zip': 'A-1060', 'city': 'Vienna', 'country': 'Austria', 'facility': 'GSK Investigational Site', 'geoPoint': {'lat': 48.20849, 'lon': 16.37208}}, {'zip': 'A-1090', 'city': 'Vienna', 'country': 'Austria', 'facility': 'GSK Investigational Site', 'geoPoint': {'lat': 48.20849, 'lon': 16.37208}}, {'zip': 'A-1100', 'city': 'Vienna', 'country': 'Austria', 'facility': 'GSK Investigational Site', 'geoPoint': {'lat': 48.20849, 'lon': 16.37208}}, {'zip': '2020', 'city': 'Antwerp', 'country': 'Belgium', 'facility': 'GSK Investigational Site', 'geoPoint': {'lat': 51.22047, 'lon': 4.40026}}, {'zip': '3590', 'city': 'Diepenbeek', 'country': 'Belgium', 'facility': 'GSK Investigational Site', 'geoPoint': {'lat': 50.90769, 'lon': 5.41875}}, {'zip': '3920', 'city': 'Lommel', 'country': 'Belgium', 'facility': 'GSK Investigational Site', 'geoPoint': {'lat': 51.23074, 'lon': 5.31349}}, {'zip': '7000', 'city': 'Mons', 'country': 'Belgium', 'facility': 'GSK Investigational Site', 'geoPoint': {'lat': 50.45413, 'lon': 3.95229}}, {'zip': '5800', 'city': 'Pleven', 'country': 'Bulgaria', 'facility': 'GSK Investigational Site', 'geoPoint': {'lat': 43.41791, 'lon': 24.61666}}, {'zip': '1233', 'city': 'Sofia', 'country': 'Bulgaria', 'facility': 'GSK Investigational Site', 'geoPoint': {'lat': 42.69751, 'lon': 23.32415}}, {'zip': '1431/1000', 'city': 'Sofia', 'country': 'Bulgaria', 'facility': 'GSK Investigational Site', 'geoPoint': {'lat': 42.69751, 'lon': 23.32415}}, {'zip': '1431', 'city': 'Sofia', 'country': 'Bulgaria', 'facility': 'GSK Investigational Site', 'geoPoint': {'lat': 42.69751, 'lon': 23.32415}}, {'zip': '9010', 'city': 'Varna', 'country': 'Bulgaria', 'facility': 'GSK Investigational Site', 'geoPoint': {'lat': 43.21912, 'lon': 27.91024}}, {'zip': 'T5K 2A2', 'city': 'Edmonton', 'state': 'Alberta', 'country': 'Canada', 'facility': 'GSK Investigational Site', 'geoPoint': {'lat': 53.55014, 'lon': -113.46871}}, {'zip': 'V2A 3G8', 'city': 'Penticton', 'state': 'British Columbia', 'country': 'Canada', 'facility': 'GSK Investigational Site', 'geoPoint': {'lat': 49.48062, 'lon': -119.58584}}, {'zip': 'V8P 5P6', 'city': 'Victoria', 'state': 'British Columbia', 'country': 'Canada', 'facility': 'GSK Investigational Site', 'geoPoint': {'lat': 48.4359, 'lon': -123.35155}}, {'zip': 'R3A 1M3', 'city': 'Winnipeg', 'state': 'Manitoba', 'country': 'Canada', 'facility': 'GSK Investigational Site', 'geoPoint': {'lat': 49.8844, 'lon': -97.14704}}, {'zip': 'A1B 3E1', 'city': "St. John's", 'state': 'Newfoundland and Labrador', 'country': 'Canada', 'facility': 'GSK Investigational Site', 'geoPoint': {'lat': 47.56494, 'lon': -52.70931}}, {'zip': 'N2M 5N6', 'city': 'Kitchener', 'state': 'Ontario', 'country': 'Canada', 'facility': 'GSK Investigational Site', 'geoPoint': {'lat': 43.42537, 'lon': -80.5112}}, {'zip': 'L5M 2V8', 'city': 'Mississauga', 'state': 'Ontario', 'country': 'Canada', 'facility': 'GSK Investigational Site', 'geoPoint': {'lat': 43.5789, 'lon': -79.6583}}, {'zip': 'M4N 3M5', 'city': 'Toronto', 'state': 'Ontario', 'country': 'Canada', 'facility': 'GSK Investigational Site', 'geoPoint': {'lat': 43.70643, 'lon': -79.39864}}, {'zip': 'M5T 2S8', 'city': 'Toronto', 'state': 'Ontario', 'country': 'Canada', 'facility': 'GSK Investigational Site', 'geoPoint': {'lat': 43.70643, 'lon': -79.39864}}, {'zip': 'M9W 4L6', 'city': 'Toronto', 'state': 'Ontario', 'country': 'Canada', 'facility': 'GSK Investigational Site', 'geoPoint': {'lat': 43.70643, 'lon': -79.39864}}, {'zip': 'N8X 5A6', 'city': 'Windsor', 'state': 'Ontario', 'country': 'Canada', 'facility': 'GSK Investigational Site', 'geoPoint': {'lat': 42.30008, 'lon': -83.01654}}, {'zip': 'H3T 1E2', 'city': 'Montreal', 'state': 'Quebec', 'country': 'Canada', 'facility': 'GSK Investigational Site', 'geoPoint': {'lat': 45.50884, 'lon': -73.58781}}, {'zip': 'H3Z 2Z3', 'city': 'Montreal', 'state': 'Quebec', 'country': 'Canada', 'facility': 'GSK Investigational Site', 'geoPoint': {'lat': 45.50884, 'lon': -73.58781}}, {'zip': 'J7Z 5T3', 'city': 'Saint-Jérôme', 'state': 'Quebec', 'country': 'Canada', 'facility': 'GSK Investigational Site', 'geoPoint': {'lat': 45.78036, 'lon': -74.00365}}, {'zip': 'G1W 4R4', 'city': 'Sainte-Foy', 'state': 'Quebec', 'country': 'Canada', 'facility': 'GSK Investigational Site', 'geoPoint': {'lat': 46.78139, 'lon': -71.29217}}, {'zip': 'G8Z 1Y2', 'city': 'Trois-Rivières', 'state': 'Quebec', 'country': 'Canada', 'facility': 'GSK Investigational Site', 'geoPoint': {'lat': 46.34515, 'lon': -72.5477}}, {'zip': 'S7N 0W8', 'city': 'Saskatoon', 'state': 'Saskatchewan', 'country': 'Canada', 'facility': 'GSK Investigational Site', 'geoPoint': {'lat': 52.13238, 'lon': -106.66892}}, {'city': 'Viña del Mar', 'state': 'Región de Valparaíso', 'country': 'Chile', 'facility': 'GSK Investigational Site', 'geoPoint': {'lat': -33.02457, 'lon': -71.55183}}, {'zip': '8380456', 'city': 'Santiago', 'state': 'Región Metro de Santiago', 'country': 'Chile', 'facility': 'GSK Investigational Site', 'geoPoint': {'lat': -33.45694, 'lon': -70.64827}}, {'city': 'Santiago', 'state': 'Región Metro de Santiago', 'country': 'Chile', 'facility': 'GSK Investigational Site', 'geoPoint': {'lat': -33.45694, 'lon': -70.64827}}, {'city': 'San José', 'country': 'Costa Rica', 'facility': 'GSK Investigational Site', 'geoPoint': {'lat': 9.93388, 'lon': -84.08489}}, {'zip': '9000', 'city': 'Aalborg', 'country': 'Denmark', 'facility': 'GSK Investigational Site', 'geoPoint': {'lat': 57.048, 'lon': 9.9187}}, {'zip': '2635', 'city': 'Ishøj', 'country': 'Denmark', 'facility': 'GSK Investigational Site', 'geoPoint': {'lat': 55.61543, 'lon': 12.35182}}, {'zip': '5000', 'city': 'Odense C', 'country': 'Denmark', 'facility': 'GSK Investigational Site', 'geoPoint': {'lat': 55.40841, 'lon': 10.39538}}, {'zip': '7100', 'city': 'Vejle', 'country': 'Denmark', 'facility': 'GSK Investigational Site', 'geoPoint': {'lat': 55.70927, 'lon': 9.5357}}, {'zip': '00100', 'city': 'Helsinki', 'country': 'Finland', 'facility': 'GSK Investigational Site', 'geoPoint': {'lat': 60.16952, 'lon': 24.93545}}, {'zip': '05800', 'city': 'Hyvinkää', 'country': 'Finland', 'facility': 'GSK Investigational Site', 'geoPoint': {'lat': 60.63195, 'lon': 24.8606}}, {'zip': '70100', 'city': 'Kuopio', 'country': 'Finland', 'facility': 'GSK Investigational Site', 'geoPoint': {'lat': 62.89238, 'lon': 27.67703}}, {'zip': '49100', 'city': 'Angers', 'country': 'France', 'facility': 'GSK Investigational Site', 'geoPoint': {'lat': 47.47156, 'lon': -0.55202}}, {'zip': '46005', 'city': 'Cahors', 'country': 'France', 'facility': 'GSK Investigational Site', 'geoPoint': {'lat': 44.4491, 'lon': 1.43663}}, {'zip': '91380', 'city': 'Chilly-Mazarin', 'country': 'France', 'facility': 'GSK Investigational Site', 'geoPoint': {'lat': 48.71489, 'lon': 2.31638}}, {'zip': '91106', 'city': 'Corbeil-Essonnes', 'country': 'France', 'facility': 'GSK Investigational Site', 'geoPoint': {'lat': 48.60603, 'lon': 2.48757}}, {'zip': '38042', 'city': 'Grenoble', 'country': 'France', 'facility': 'GSK Investigational Site', 'geoPoint': {'lat': 45.17869, 'lon': 5.71479}}, {'zip': '69002', 'city': 'Lyon', 'country': 'France', 'facility': 'GSK Investigational Site', 'geoPoint': {'lat': 45.74906, 'lon': 4.84789}}, {'zip': '75571', 'city': 'Paris', 'country': 'France', 'facility': 'GSK Investigational Site', 'geoPoint': {'lat': 48.85341, 'lon': 2.3488}}, {'zip': '31300', 'city': 'Toulouse', 'country': 'France', 'facility': 'GSK Investigational Site', 'geoPoint': {'lat': 43.60426, 'lon': 1.44367}}, {'zip': '37000', 'city': 'Tours', 'country': 'France', 'facility': 'GSK Investigational Site', 'geoPoint': {'lat': 47.39484, 'lon': 0.70398}}, {'zip': '76530', 'city': 'Baden-Baden', 'state': 'Baden-Wurttemberg', 'country': 'Germany', 'facility': 'GSK Investigational Site', 'geoPoint': {'lat': 48.7606, 'lon': 8.23975}}, {'zip': '73326', 'city': 'Deggingen', 'state': 'Baden-Wurttemberg', 'country': 'Germany', 'facility': 'GSK Investigational Site', 'geoPoint': {'lat': 48.5971, 'lon': 9.71891}}, {'zip': '79098', 'city': 'Freiburg im Breisgau', 'state': 'Baden-Wurttemberg', 'country': 'Germany', 'facility': 'GSK Investigational Site', 'geoPoint': {'lat': 47.9959, 'lon': 7.85222}}, {'zip': '77971', 'city': 'Kippenheim', 'state': 'Baden-Wurttemberg', 'country': 'Germany', 'facility': 'GSK Investigational Site', 'geoPoint': {'lat': 48.29564, 'lon': 7.8251}}, {'zip': '66111', 'city': 'Stuttgart', 'state': 'Baden-Wurttemberg', 'country': 'Germany', 'facility': 'GSK Investigational Site', 'geoPoint': {'lat': 48.78232, 'lon': 9.17702}}, {'zip': '70469', 'city': 'Stuttgart', 'state': 'Baden-Wurttemberg', 'country': 'Germany', 'facility': 'GSK Investigational Site', 'geoPoint': {'lat': 48.78232, 'lon': 9.17702}}, {'zip': '69469', 'city': 'Weinheim', 'state': 'Baden-Wurttemberg', 'country': 'Germany', 'facility': 'GSK Investigational Site', 'geoPoint': {'lat': 49.54887, 'lon': 8.66697}}, {'zip': '95445', 'city': 'Bayreuth', 'state': 'Bavaria', 'country': 'Germany', 'facility': 'GSK Investigational Site', 'geoPoint': {'lat': 49.94782, 'lon': 11.57893}}, {'zip': '91054', 'city': 'Erlangen', 'state': 'Bavaria', 'country': 'Germany', 'facility': 'GSK Investigational Site', 'geoPoint': {'lat': 49.59099, 'lon': 11.00783}}, {'zip': '80333', 'city': 'Munich', 'state': 'Bavaria', 'country': 'Germany', 'facility': 'GSK Investigational Site', 'geoPoint': {'lat': 48.13743, 'lon': 11.57549}}, {'zip': '80339', 'city': 'Munich', 'state': 'Bavaria', 'country': 'Germany', 'facility': 'GSK Investigational Site', 'geoPoint': {'lat': 48.13743, 'lon': 11.57549}}, {'zip': '90402', 'city': 'Nuremberg', 'state': 'Bavaria', 'country': 'Germany', 'facility': 'GSK Investigational Site', 'geoPoint': {'lat': 49.45421, 'lon': 11.07752}}, {'zip': '94032', 'city': 'Passau', 'state': 'Bavaria', 'country': 'Germany', 'facility': 'GSK Investigational Site', 'geoPoint': {'lat': 48.5665, 'lon': 13.43122}}, {'zip': '20249', 'city': 'Hamburg', 'state': 'Hamburg', 'country': 'Germany', 'facility': 'GSK Investigational Site', 'geoPoint': {'lat': 53.55073, 'lon': 9.99302}}, {'zip': '22143', 'city': 'Hamburg', 'state': 'Hamburg', 'country': 'Germany', 'facility': 'GSK Investigational Site', 'geoPoint': {'lat': 53.55073, 'lon': 9.99302}}, {'zip': '22415', 'city': 'Hamburg', 'state': 'Hamburg', 'country': 'Germany', 'facility': 'GSK Investigational Site', 'geoPoint': {'lat': 53.55073, 'lon': 9.99302}}, {'zip': '35625', 'city': 'Hüttenberg', 'state': 'Hesse', 'country': 'Germany', 'facility': 'GSK Investigational Site', 'geoPoint': {'lat': 50.51453, 'lon': 8.62189}}, {'zip': '65185', 'city': 'Wiesbaden', 'state': 'Hesse', 'country': 'Germany', 'facility': 'GSK Investigational Site', 'geoPoint': {'lat': 50.08601, 'lon': 8.24435}}, {'zip': '37574', 'city': 'Einbeck', 'state': 'Lower Saxony', 'country': 'Germany', 'facility': 'GSK Investigational Site', 'geoPoint': {'lat': 51.82018, 'lon': 9.86961}}, {'zip': '30519', 'city': 'Hanover', 'state': 'Lower Saxony', 'country': 'Germany', 'facility': 'GSK Investigational Site', 'geoPoint': {'lat': 52.37052, 'lon': 9.73322}}, {'zip': '31134', 'city': 'Hildesheim', 'state': 'Lower Saxony', 'country': 'Germany', 'facility': 'GSK Investigational Site', 'geoPoint': {'lat': 52.15077, 'lon': 9.95112}}, {'zip': '19055', 'city': 'Schwerin', 'state': 'Mecklenburg-Vorpommern', 'country': 'Germany', 'facility': 'GSK Investigational Site', 'geoPoint': {'lat': 53.62937, 'lon': 11.41316}}, {'zip': '52064', 'city': 'Aachen', 'state': 'North Rhine-Westphalia', 'country': 'Germany', 'facility': 'GSK Investigational Site', 'geoPoint': {'lat': 50.77664, 'lon': 6.08342}}, {'zip': '59269', 'city': 'Beckum', 'state': 'North Rhine-Westphalia', 'country': 'Germany', 'facility': 'GSK Investigational Site', 'geoPoint': {'lat': 51.75571, 'lon': 8.04075}}, {'zip': '44787', 'city': 'Bochum', 'state': 'North Rhine-Westphalia', 'country': 'Germany', 'facility': 'GSK Investigational Site', 'geoPoint': {'lat': 51.48165, 'lon': 7.21648}}, {'zip': '51069', 'city': 'Cologne', 'state': 'North Rhine-Westphalia', 'country': 'Germany', 'facility': 'GSK Investigational Site', 'geoPoint': {'lat': 50.93333, 'lon': 6.95}}, {'zip': '45326', 'city': 'Essen', 'state': 'North Rhine-Westphalia', 'country': 'Germany', 'facility': 'GSK Investigational Site', 'geoPoint': {'lat': 51.45657, 'lon': 7.01228}}, {'zip': '47574', 'city': 'Goch', 'state': 'North Rhine-Westphalia', 'country': 'Germany', 'facility': 'GSK Investigational Site', 'geoPoint': {'lat': 51.67873, 'lon': 6.15895}}, {'zip': '45525', 'city': 'Hattingen', 'state': 'North Rhine-Westphalia', 'country': 'Germany', 'facility': 'GSK Investigational Site', 'geoPoint': {'lat': 51.39894, 'lon': 7.18557}}, {'zip': '48155', 'city': 'Münster', 'state': 'North Rhine-Westphalia', 'country': 'Germany', 'facility': 'GSK Investigational Site', 'geoPoint': {'lat': 51.96236, 'lon': 7.62571}}, {'zip': '58455', 'city': 'Witten', 'state': 'North Rhine-Westphalia', 'country': 'Germany', 'facility': 'GSK Investigational Site', 'geoPoint': {'lat': 51.44362, 'lon': 7.35258}}, {'zip': '55624', 'city': 'Rhaunen', 'state': 'Rhineland-Palatinate', 'country': 'Germany', 'facility': 'GSK Investigational Site', 'geoPoint': {'lat': 49.8638, 'lon': 7.34198}}, {'zip': '66111', 'city': 'Saarbrücken', 'state': 'Saarland', 'country': 'Germany', 'facility': 'GSK Investigational Site', 'geoPoint': {'lat': 49.23262, 'lon': 7.00982}}, {'zip': '09111', 'city': 'Chemnitz', 'state': 'Saxony', 'country': 'Germany', 'facility': 'GSK Investigational Site', 'geoPoint': {'lat': 50.8357, 'lon': 12.92922}}, {'zip': '04509', 'city': 'Delitzsch', 'state': 'Saxony', 'country': 'Germany', 'facility': 'GSK Investigational Site', 'geoPoint': {'lat': 51.52546, 'lon': 12.34284}}, {'zip': '01067', 'city': 'Dresden', 'state': 'Saxony', 'country': 'Germany', 'facility': 'GSK Investigational Site', 'geoPoint': {'lat': 51.05089, 'lon': 13.73832}}, {'zip': '01705', 'city': 'Freital', 'state': 'Saxony', 'country': 'Germany', 'facility': 'GSK Investigational Site', 'geoPoint': {'lat': 51.00166, 'lon': 13.6488}}, {'zip': '02826', 'city': 'Görlitz', 'state': 'Saxony', 'country': 'Germany', 'facility': 'GSK Investigational Site', 'geoPoint': {'lat': 51.15518, 'lon': 14.98853}}, {'zip': '04107', 'city': 'Leipzig', 'state': 'Saxony', 'country': 'Germany', 'facility': 'GSK Investigational Site', 'geoPoint': {'lat': 51.33962, 'lon': 12.37129}}, {'zip': '04229', 'city': 'Leipzig', 'state': 'Saxony', 'country': 'Germany', 'facility': 'GSK Investigational Site', 'geoPoint': {'lat': 51.33962, 'lon': 12.37129}}, {'zip': '01762', 'city': 'Schmiedeberg', 'state': 'Saxony', 'country': 'Germany', 'facility': 'GSK Investigational Site', 'geoPoint': {'lat': 50.83644, 'lon': 13.67622}}, {'zip': '39326', 'city': 'Wolmirstedt', 'state': 'Saxony-Anhalt', 'country': 'Germany', 'facility': 'GSK Investigational Site', 'geoPoint': {'lat': 52.24856, 'lon': 11.62945}}, {'zip': '25335', 'city': 'Elmshorn', 'state': 'Schleswig-Holstein', 'country': 'Germany', 'facility': 'GSK Investigational Site', 'geoPoint': {'lat': 53.74912, 'lon': 9.66176}}, {'zip': '23538', 'city': 'Lübeck', 'state': 'Schleswig-Holstein', 'country': 'Germany', 'facility': 'GSK Investigational Site', 'geoPoint': {'lat': 53.86893, 'lon': 10.68729}}, {'zip': '25421', 'city': 'Pinneberg', 'state': 'Schleswig-Holstein', 'country': 'Germany', 'facility': 'GSK Investigational Site', 'geoPoint': {'lat': 53.65887, 'lon': 9.79698}}, {'zip': '10777', 'city': 'Berlin', 'state': 'State of Berlin', 'country': 'Germany', 'facility': 'GSK Investigational Site', 'geoPoint': {'lat': 52.52437, 'lon': 13.41053}}, {'zip': '12247', 'city': 'Berlin', 'state': 'State of Berlin', 'country': 'Germany', 'facility': 'GSK Investigational Site', 'geoPoint': {'lat': 52.52437, 'lon': 13.41053}}, {'zip': '13125', 'city': 'Berlin', 'state': 'State of Berlin', 'country': 'Germany', 'facility': 'GSK Investigational Site', 'geoPoint': {'lat': 52.52437, 'lon': 13.41053}}, {'zip': '14057', 'city': 'Berlin', 'state': 'State of Berlin', 'country': 'Germany', 'facility': 'GSK Investigational Site', 'geoPoint': {'lat': 52.52437, 'lon': 13.41053}}, {'zip': '14109', 'city': 'Berlin', 'state': 'State of Berlin', 'country': 'Germany', 'facility': 'GSK Investigational Site', 'geoPoint': {'lat': 52.52437, 'lon': 13.41053}}, {'zip': '65403', 'city': 'Kavala', 'country': 'Greece', 'facility': 'GSK Investigational Site', 'geoPoint': {'lat': 40.93959, 'lon': 24.40687}}, {'zip': '546 36', 'city': 'Thessaloniki', 'country': 'Greece', 'facility': 'GSK Investigational Site', 'geoPoint': {'lat': 40.64072, 'lon': 22.93493}}, {'zip': '54642', 'city': 'Thessaloniki', 'country': 'Greece', 'facility': 'GSK Investigational Site', 'geoPoint': {'lat': 40.64072, 'lon': 22.93493}}, {'zip': '564 29', 'city': 'Thessaloniki', 'country': 'Greece', 'facility': 'GSK Investigational Site', 'geoPoint': {'lat': 40.64072, 'lon': 22.93493}}, {'zip': '1023', 'city': 'Budapest', 'country': 'Hungary', 'facility': 'GSK Investigational Site', 'geoPoint': {'lat': 47.49835, 'lon': 19.04045}}, {'zip': '1238', 'city': 'Budapest', 'country': 'Hungary', 'facility': 'GSK Investigational Site', 'geoPoint': {'lat': 47.49835, 'lon': 19.04045}}, {'city': 'Budapest', 'country': 'Hungary', 'facility': 'GSK Investigational Site', 'geoPoint': {'lat': 47.49835, 'lon': 19.04045}}, {'zip': '9024', 'city': 'Győr', 'country': 'Hungary', 'facility': 'GSK Investigational Site', 'geoPoint': {'lat': 47.68333, 'lon': 17.63512}}, {'zip': '560 017', 'city': 'Bangalore', 'country': 'India', 'facility': 'GSK Investigational Site', 'geoPoint': {'lat': 12.97194, 'lon': 77.59369}}, {'zip': '560 054', 'city': 'Bangalore', 'country': 'India', 'facility': 'GSK Investigational Site', 'geoPoint': {'lat': 12.97194, 'lon': 77.59369}}, {'zip': '560034', 'city': 'Bangalore', 'country': 'India', 'facility': 'GSK Investigational Site', 'geoPoint': {'lat': 12.97194, 'lon': 77.59369}}, {'zip': '600003', 'city': 'Chennai', 'country': 'India', 'facility': 'GSK Investigational Site', 'geoPoint': {'lat': 13.08784, 'lon': 80.27847}}, {'zip': '500 004', 'city': 'Hyderabad', 'country': 'India', 'facility': 'GSK Investigational Site', 'geoPoint': {'lat': 17.38405, 'lon': 78.45636}}, {'zip': '500482', 'city': 'Hyderabad, Andhra Pradesh', 'country': 'India', 'facility': 'GSK Investigational Site', 'geoPoint': {'lat': 17.38405, 'lon': 78.45636}}, {'city': 'New Delhi', 'country': 'India', 'facility': 'GSK Investigational Site', 'geoPoint': {'lat': 28.62137, 'lon': 77.2148}}, {'zip': '411 001', 'city': 'Pune', 'country': 'India', 'facility': 'GSK Investigational Site', 'geoPoint': {'lat': 18.51957, 'lon': 73.85535}}, {'zip': '9', 'city': 'Dublin', 'country': 'Ireland', 'facility': 'GSK Investigational Site', 'geoPoint': {'lat': 53.33306, 'lon': -6.24889}}, {'city': 'Waterford', 'country': 'Ireland', 'facility': 'GSK Investigational Site', 'geoPoint': {'lat': 52.25833, 'lon': -7.11194}}, {'zip': '65100', 'city': 'Pescara', 'state': 'Abruzzo', 'country': 'Italy', 'facility': 'GSK Investigational Site', 'geoPoint': {'lat': 42.4584, 'lon': 14.20283}}, {'zip': '82100', 'city': 'Benevento', 'state': 'Campania', 'country': 'Italy', 'facility': 'GSK Investigational Site', 'geoPoint': {'lat': 41.1307, 'lon': 14.77816}}, {'zip': '82100', 'city': 'Telese Terme (BN)', 'state': 'Campania', 'country': 'Italy', 'facility': 'GSK Investigational Site', 'geoPoint': {'lat': 41.21752, 'lon': 14.52681}}, {'zip': '16011', 'city': 'Arenzano (GE)', 'state': 'Liguria', 'country': 'Italy', 'facility': 'GSK Investigational Site', 'geoPoint': {'lat': 44.40521, 'lon': 8.68315}}, {'zip': '16148', 'city': 'Genoa', 'state': 'Liguria', 'country': 'Italy', 'facility': 'GSK Investigational Site', 'geoPoint': {'lat': 44.40478, 'lon': 8.94439}}, {'zip': '20089', 'city': 'Rozzano (MI)', 'state': 'Lombardy', 'country': 'Italy', 'facility': 'GSK Investigational Site', 'geoPoint': {'lat': 45.38193, 'lon': 9.1559}}, {'zip': '56126', 'city': 'Pisa', 'state': 'Tuscany', 'country': 'Italy', 'facility': 'GSK Investigational Site', 'geoPoint': {'lat': 43.70853, 'lon': 10.4036}}, {'zip': '59100', 'city': 'Prato', 'state': 'Tuscany', 'country': 'Italy', 'facility': 'GSK Investigational Site', 'geoPoint': {'lat': 43.8805, 'lon': 11.09699}}, {'zip': '05100', 'city': 'Terni', 'state': 'Umbria', 'country': 'Italy', 'facility': 'GSK Investigational Site', 'geoPoint': {'lat': 42.56335, 'lon': 12.64329}}, {'zip': '31044', 'city': 'Montebelluna (TV)', 'state': 'Veneto', 'country': 'Italy', 'facility': 'GSK Investigational Site', 'geoPoint': {'lat': 45.77504, 'lon': 12.04904}}, {'zip': 'LV3400', 'city': 'Liepāja', 'country': 'Latvia', 'facility': 'GSK Investigational Site', 'geoPoint': {'lat': 56.50474, 'lon': 21.01085}}, {'zip': 'LV 1002', 'city': 'Riga', 'country': 'Latvia', 'facility': 'GSK Investigational Site', 'geoPoint': {'lat': 56.946, 'lon': 24.10589}}, {'zip': 'LV1079', 'city': 'Riga', 'country': 'Latvia', 'facility': 'GSK Investigational Site', 'geoPoint': {'lat': 56.946, 'lon': 24.10589}}, {'city': 'Valmiera', 'country': 'Latvia', 'facility': 'GSK Investigational Site', 'geoPoint': {'lat': 57.54108, 'lon': 25.42751}}, {'zip': '44280', 'city': 'Guadalajara', 'state': 'Jalisco', 'country': 'Mexico', 'facility': 'GSK Investigational Site', 'geoPoint': {'lat': 20.67738, 'lon': -103.34749}}, {'zip': '44340', 'city': 'Guadalajara', 'state': 'Jalisco', 'country': 'Mexico', 'facility': 'GSK Investigational Site', 'geoPoint': {'lat': 20.67738, 'lon': -103.34749}}, {'zip': '64020', 'city': 'Monterrey', 'state': 'Nuevo León', 'country': 'Mexico', 'facility': 'GSK Investigational Site', 'geoPoint': {'lat': 25.68435, 'lon': -100.31721}}, {'zip': '06720', 'city': 'Mexico City', 'country': 'Mexico', 'facility': 'GSK Investigational Site', 'geoPoint': {'lat': 19.42847, 'lon': -99.12766}}, {'zip': '06700', 'city': 'México', 'country': 'Mexico', 'facility': 'GSK Investigational Site', 'geoPoint': {'lat': 31.00435, 'lon': -108.15213}}, {'city': 'México', 'country': 'Mexico', 'facility': 'GSK Investigational Site', 'geoPoint': {'lat': 31.00435, 'lon': -108.15213}}, {'zip': '4872 LA', 'city': 'Etten-Leur', 'country': 'Netherlands', 'facility': 'GSK Investigational Site', 'geoPoint': {'lat': 51.57056, 'lon': 4.63726}}, {'zip': '2803 HH', 'city': 'Gouda', 'country': 'Netherlands', 'facility': 'GSK Investigational Site', 'geoPoint': {'lat': 52.01667, 'lon': 4.70833}}, {'zip': '6416 EG', 'city': 'Heerlen', 'country': 'Netherlands', 'facility': 'GSK Investigational Site', 'geoPoint': {'lat': 50.88365, 'lon': 5.98154}}, {'zip': '6525 GA', 'city': 'Nijmegen', 'country': 'Netherlands', 'facility': 'GSK Investigational Site', 'geoPoint': {'lat': 51.8425, 'lon': 5.85278}}, {'zip': '2597 AX', 'city': 'The Hague', 'country': 'Netherlands', 'facility': 'GSK Investigational Site', 'geoPoint': {'lat': 52.07667, 'lon': 4.29861}}, {'zip': '8011 JW', 'city': 'Zwolle', 'country': 'Netherlands', 'facility': 'GSK Investigational Site', 'geoPoint': {'lat': 52.5125, 'lon': 6.09444}}, {'zip': '1309', 'city': 'Auckland', 'country': 'New Zealand', 'facility': 'GSK Investigational Site', 'geoPoint': {'lat': -36.84853, 'lon': 174.76349}}, {'zip': '1701', 'city': 'Auckland', 'country': 'New Zealand', 'facility': 'GSK Investigational Site', 'geoPoint': {'lat': -36.84853, 'lon': 174.76349}}, {'zip': '8001', 'city': 'Christchurch', 'country': 'New Zealand', 'facility': 'GSK Investigational Site', 'geoPoint': {'lat': -43.53333, 'lon': 172.63333}}, {'zip': '6009', 'city': 'Lower Hutt', 'country': 'New Zealand', 'facility': 'GSK Investigational Site', 'geoPoint': {'lat': -41.21667, 'lon': 174.91667}}, {'zip': '3201', 'city': 'Rotorua', 'country': 'New Zealand', 'facility': 'GSK Investigational Site', 'geoPoint': {'lat': -38.13874, 'lon': 176.24516}}, {'zip': '9480', 'city': 'Harstad', 'country': 'Norway', 'facility': 'GSK Investigational Site', 'geoPoint': {'lat': 68.79833, 'lon': 16.54165}}, {'zip': '7600', 'city': 'Levanger', 'country': 'Norway', 'facility': 'GSK Investigational Site', 'geoPoint': {'lat': 63.74644, 'lon': 11.29963}}, {'zip': '2609', 'city': 'Lillehammer', 'country': 'Norway', 'facility': 'GSK Investigational Site', 'geoPoint': {'lat': 61.11514, 'lon': 10.46628}}, {'zip': '3722', 'city': 'Skien', 'country': 'Norway', 'facility': 'GSK Investigational Site', 'geoPoint': {'lat': 59.20962, 'lon': 9.60897}}, {'zip': 'N-3117', 'city': 'Tønsberg', 'country': 'Norway', 'facility': 'GSK Investigational Site', 'geoPoint': {'lat': 59.26754, 'lon': 10.40762}}, {'zip': 'Lima 27', 'city': 'Lima', 'state': 'Lima Province', 'country': 'Peru', 'facility': 'GSK Investigational Site', 'geoPoint': {'lat': -12.04318, 'lon': -77.02824}}, {'zip': 'Callao 2', 'city': 'Callao', 'country': 'Peru', 'facility': 'GSK Investigational Site', 'geoPoint': {'lat': -12.05162, 'lon': -77.13452}}, {'zip': 'Lima 27', 'city': 'Lima', 'country': 'Peru', 'facility': 'GSK Investigational Site', 'geoPoint': {'lat': -12.04318, 'lon': -77.02824}}, {'zip': 'Lima 39', 'city': 'Lima', 'country': 'Peru', 'facility': 'GSK Investigational Site', 'geoPoint': {'lat': -12.04318, 'lon': -77.02824}}, {'zip': '1000', 'city': 'Manila', 'country': 'Philippines', 'facility': 'GSK Investigational Site', 'geoPoint': {'lat': 14.6042, 'lon': 120.9822}}, {'zip': '1003', 'city': 'Manila', 'country': 'Philippines', 'facility': 'GSK Investigational Site', 'geoPoint': {'lat': 14.6042, 'lon': 120.9822}}, {'zip': '86-300', 'city': 'Grudziądz', 'country': 'Poland', 'facility': 'GSK Investigational Site', 'geoPoint': {'lat': 53.48411, 'lon': 18.75366}}, {'zip': '61-544', 'city': 'Poznan', 'country': 'Poland', 'facility': 'GSK Investigational Site', 'geoPoint': {'lat': 52.40692, 'lon': 16.92993}}, {'zip': '02-341', 'city': 'Warsaw', 'country': 'Poland', 'facility': 'GSK Investigational Site', 'geoPoint': {'lat': 52.22977, 'lon': 21.01178}}, {'zip': '50-044', 'city': 'Wroclaw', 'country': 'Poland', 'facility': 'GSK Investigational Site', 'geoPoint': {'lat': 51.10286, 'lon': 17.03006}}, {'zip': '50-088', 'city': 'Wroclaw', 'country': 'Poland', 'facility': 'GSK Investigational Site', 'geoPoint': {'lat': 51.10286, 'lon': 17.03006}}, {'zip': '00726', 'city': 'Caguas', 'state': 'Puerto Rico', 'country': 'Puerto Rico', 'facility': 'GSK Investigational Site', 'geoPoint': {'lat': 18.23412, 'lon': -66.0485}}, {'zip': '500366', 'city': 'Brasov', 'country': 'Romania', 'facility': 'GSK Investigational Site', 'geoPoint': {'lat': 45.64861, 'lon': 25.60613}}, {'zip': '11172', 'city': 'Bucharest', 'country': 'Romania', 'facility': 'GSK Investigational Site', 'geoPoint': {'lat': 44.43225, 'lon': 26.10626}}, {'zip': '20983', 'city': 'Bucharest', 'country': 'Romania', 'facility': 'GSK Investigational Site', 'geoPoint': {'lat': 44.43225, 'lon': 26.10626}}, {'city': 'Bucharest', 'country': 'Romania', 'facility': 'GSK Investigational Site', 'geoPoint': {'lat': 44.43225, 'lon': 26.10626}}, {'zip': '115522', 'city': 'Moscow', 'country': 'Russia', 'facility': 'GSK Investigational Site', 'geoPoint': {'lat': 55.75204, 'lon': 37.61781}}, {'zip': '119049', 'city': 'Moscow', 'country': 'Russia', 'facility': 'GSK Investigational Site', 'geoPoint': {'lat': 55.75204, 'lon': 37.61781}}, {'zip': '129327', 'city': 'Moscow', 'country': 'Russia', 'facility': 'GSK Investigational Site', 'geoPoint': {'lat': 55.75204, 'lon': 37.61781}}, {'city': 'Moscow', 'country': 'Russia', 'facility': 'GSK Investigational Site', 'geoPoint': {'lat': 55.75204, 'lon': 37.61781}}, {'zip': '390026', 'city': 'Ryazan', 'country': 'Russia', 'facility': 'GSK Investigational Site', 'geoPoint': {'lat': 54.62696, 'lon': 39.70415}}, {'city': 'Saint Petersburg', 'country': 'Russia', 'facility': 'GSK Investigational Site', 'geoPoint': {'lat': 59.93863, 'lon': 30.31413}}, {'zip': '410053', 'city': 'Saratov', 'country': 'Russia', 'facility': 'GSK Investigational Site', 'geoPoint': {'lat': 51.54048, 'lon': 45.9901}}, {'zip': '300053', 'city': 'Tula', 'country': 'Russia', 'facility': 'GSK Investigational Site', 'geoPoint': {'lat': 54.19609, 'lon': 37.61822}}, {'zip': '150003', 'city': 'Yaroslavl', 'country': 'Russia', 'facility': 'GSK Investigational Site', 'geoPoint': {'lat': 57.62987, 'lon': 39.87368}}, {'zip': '150062', 'city': 'Yaroslavl', 'country': 'Russia', 'facility': 'GSK Investigational Site', 'geoPoint': {'lat': 57.62987, 'lon': 39.87368}}, {'zip': '620102', 'city': 'Yekaterinburg', 'country': 'Russia', 'facility': 'GSK Investigational Site', 'geoPoint': {'lat': 56.85733, 'lon': 60.61529}}, {'zip': '6020', 'city': 'Korsten', 'state': 'Eastern Cape', 'country': 'South Africa', 'facility': 'GSK Investigational Site', 'geoPoint': {'lat': -33.92228, 'lon': 25.57755}}, {'city': 'Boksburg', 'state': 'Gauteng', 'country': 'South Africa', 'facility': 'GSK Investigational Site', 'geoPoint': {'lat': -26.21197, 'lon': 28.25958}}, {'zip': '0001', 'city': 'Muckleneuk', 'state': 'Gauteng', 'country': 'South Africa', 'facility': 'GSK Investigational Site'}, {'zip': '2193', 'city': 'Parktown', 'state': 'Gauteng', 'country': 'South Africa', 'facility': 'GSK Investigational Site', 'geoPoint': {'lat': -26.18205, 'lon': 28.02671}}, {'zip': '7525', 'city': 'Cape Town', 'country': 'South Africa', 'facility': 'GSK Investigational Site', 'geoPoint': {'lat': -33.92584, 'lon': 18.42322}}, {'zip': '4001', 'city': 'Durban', 'country': 'South Africa', 'facility': 'GSK Investigational Site', 'geoPoint': {'lat': -29.8579, 'lon': 31.0292}}, {'zip': '0048', 'city': 'Erasmus Kloof, Pretoria', 'country': 'South Africa', 'facility': 'GSK Investigational Site'}, {'zip': '1619', 'city': 'Kempton Park', 'country': 'South Africa', 'facility': 'GSK Investigational Site', 'geoPoint': {'lat': -26.10859, 'lon': 28.2377}}, {'zip': '7925', 'city': 'Observatory', 'country': 'South Africa', 'facility': 'GSK Investigational Site', 'geoPoint': {'lat': -33.93613, 'lon': 18.46787}}, {'zip': '7405', 'city': 'Pinetown', 'country': 'South Africa', 'facility': 'GSK Investigational Site', 'geoPoint': {'lat': -29.82068, 'lon': 30.88674}}, {'zip': '431-070', 'city': 'Anyang-si', 'country': 'South Korea', 'facility': 'GSK Investigational Site', 'geoPoint': {'lat': 37.3925, 'lon': 126.92694}}, {'zip': '705-718', 'city': 'Daegu', 'country': 'South Korea', 'facility': 'GSK Investigational Site', 'geoPoint': {'lat': 35.87028, 'lon': 128.59111}}, {'zip': '110-744', 'city': 'Seoul', 'country': 'South Korea', 'facility': 'GSK Investigational Site', 'geoPoint': {'lat': 37.566, 'lon': 126.9784}}, {'zip': '120-752', 'city': 'Seoul', 'country': 'South Korea', 'facility': 'GSK Investigational Site', 'geoPoint': {'lat': 37.566, 'lon': 126.9784}}, {'zip': '138-736', 'city': 'Seoul', 'country': 'South Korea', 'facility': 'GSK Investigational Site', 'geoPoint': {'lat': 37.566, 'lon': 126.9784}}, {'city': 'Seoul', 'country': 'South Korea', 'facility': 'GSK Investigational Site', 'geoPoint': {'lat': 37.566, 'lon': 126.9784}}, {'zip': '15006', 'city': 'A Coruña', 'country': 'Spain', 'facility': 'GSK Investigational Site', 'geoPoint': {'lat': 43.37135, 'lon': -8.396}}, {'zip': '48903', 'city': 'Baracaldo/Vizcaya', 'country': 'Spain', 'facility': 'GSK Investigational Site'}, {'zip': '08003', 'city': 'Barcelona', 'country': 'Spain', 'facility': 'GSK Investigational Site', 'geoPoint': {'lat': 41.38879, 'lon': 2.15899}}, {'zip': '08025', 'city': 'Barcelona', 'country': 'Spain', 'facility': 'GSK Investigational Site', 'geoPoint': {'lat': 41.38879, 'lon': 2.15899}}, {'zip': '08035', 'city': 'Barcelona', 'country': 'Spain', 'facility': 'GSK Investigational Site', 'geoPoint': {'lat': 41.38879, 'lon': 2.15899}}, {'zip': '14004', 'city': 'Córdoba', 'country': 'Spain', 'facility': 'GSK Investigational Site', 'geoPoint': {'lat': 37.89155, 'lon': -4.77275}}, {'zip': '18014', 'city': 'Granada', 'country': 'Spain', 'facility': 'GSK Investigational Site', 'geoPoint': {'lat': 37.18817, 'lon': -3.60667}}, {'zip': '19002', 'city': 'Guadalajara', 'country': 'Spain', 'facility': 'GSK Investigational Site', 'geoPoint': {'lat': 40.62862, 'lon': -3.16185}}, {'zip': '06800', 'city': 'Mérida (Badajoz)', 'country': 'Spain', 'facility': 'GSK Investigational Site', 'geoPoint': {'lat': 38.91802, 'lon': -6.34292}}, {'zip': '33006', 'city': 'Oviedo', 'country': 'Spain', 'facility': 'GSK Investigational Site', 'geoPoint': {'lat': 43.36029, 'lon': -5.84476}}, {'zip': '31008', 'city': 'Pamplona', 'country': 'Spain', 'facility': 'GSK Investigational Site', 'geoPoint': {'lat': 42.81687, 'lon': -1.64323}}, {'zip': '20014', 'city': 'San Sebastián', 'country': 'Spain', 'facility': 'GSK Investigational Site', 'geoPoint': {'lat': 43.56667, 'lon': -5.9}}, {'zip': '15706', 'city': 'Santiago de Compostela', 'country': 'Spain', 'facility': 'GSK Investigational Site', 'geoPoint': {'lat': 42.88052, 'lon': -8.54569}}, {'zip': '41071', 'city': 'Seville', 'country': 'Spain', 'facility': 'GSK Investigational Site', 'geoPoint': {'lat': 37.38283, 'lon': -5.97317}}, {'zip': '46017', 'city': 'Valencia', 'country': 'Spain', 'facility': 'GSK Investigational Site', 'geoPoint': {'lat': 39.47391, 'lon': -0.37966}}, {'zip': '3570', 'city': 'Villajoyosa', 'country': 'Spain', 'facility': 'GSK Investigational Site', 'geoPoint': {'lat': 38.50754, 'lon': -0.23346}}, {'zip': '61002', 'city': 'Kharkiv', 'country': 'Ukraine', 'facility': 'GSK Investigational Site', 'geoPoint': {'lat': 49.98177, 'lon': 36.25475}}, {'zip': '61039', 'city': 'Kharkiv', 'country': 'Ukraine', 'facility': 'GSK Investigational Site', 'geoPoint': {'lat': 49.98177, 'lon': 36.25475}}, {'city': 'Kiev', 'country': 'Ukraine', 'facility': 'GSK Investigational Site', 'geoPoint': {'lat': 50.45466, 'lon': 30.5238}}, {'zip': '03680', 'city': 'Kyiv', 'country': 'Ukraine', 'facility': 'GSK Investigational Site', 'geoPoint': {'lat': 50.45466, 'lon': 30.5238}}, {'zip': '79010', 'city': 'Lviv', 'country': 'Ukraine', 'facility': 'GSK Investigational Site', 'geoPoint': {'lat': 49.83826, 'lon': 24.02324}}, {'zip': 'TR1 3LJ', 'city': 'Truro', 'state': 'Cornwall', 'country': 'United Kingdom', 'facility': 'GSK Investigational Site', 'geoPoint': {'lat': 50.26526, 'lon': -5.05436}}, {'zip': 'AL3 5PN', 'city': 'St Albans', 'state': 'Hertfordshire', 'country': 'United Kingdom', 'facility': 'GSK Investigational Site', 'geoPoint': {'lat': 51.75, 'lon': -0.33333}}, {'zip': 'M13 9WL', 'city': 'Manchester', 'state': 'Lancashire', 'country': 'United Kingdom', 'facility': 'GSK Investigational Site', 'geoPoint': {'lat': 53.48095, 'lon': -2.23743}}, {'zip': 'CH49 9PE', 'city': 'Metropolitan Borough of Wirral', 'state': 'Merseyside', 'country': 'United Kingdom', 'facility': 'GSK Investigational Site', 'geoPoint': {'lat': 53.37616, 'lon': -3.10501}}, {'zip': 'TW15 3AA', 'city': 'Ashford', 'state': 'Middlesex', 'country': 'United Kingdom', 'facility': 'GSK Investigational Site', 'geoPoint': {'lat': 51.14648, 'lon': 0.87376}}, {'zip': 'NN1 5BD', 'city': 'Northampton', 'state': 'Northamptonshire', 'country': 'United Kingdom', 'facility': 'GSK Investigational Site', 'geoPoint': {'lat': 52.25, 'lon': -0.88333}}], 'overallOfficials': [{'name': 'GSK Clinical Trials', 'role': 'STUDY_DIRECTOR', 'affiliation': 'GlaxoSmithKline'}]}, 'sponsorCollaboratorsModule': {'leadSponsor': {'name': 'GlaxoSmithKline', 'class': 'INDUSTRY'}, 'responsibleParty': {'type': 'SPONSOR'}}}, 'annotationSection': {'annotationModule': {'unpostedAnnotation': {'unpostedEvents': [{'date': '2017-09-06', 'type': 'RELEASE'}, {'date': '2018-08-15', 'type': 'UNRELEASE'}], 'unpostedResponsibleParty': 'GlaxoSmithKline'}}}}