Ignite Creation Date:
2025-12-24 @ 11:28 PM
Ignite Modification Date:
2026-01-01 @ 2:12 AM
Study NCT ID:
NCT01837056
Status:
COMPLETED
Last Update Posted:
2013-04-22
First Post:
2013-04-12
Is NOT Gene Therapy:
True
Has Adverse Events:
False
Brief Title:
Prevalence of Toxoplasma Gondii and Toxocara Canis Among Patients With Uveitis
Sponsor:
Organization:
Raw JSON
{'hasResults': False, 'derivedSection': {'miscInfoModule': {'versionHolder': '2025-12-24'}, 'conditionBrowseModule': {'meshes': [{'id': 'D014605', 'term': 'Uveitis'}], 'ancestors': [{'id': 'D014603', 'term': 'Uveal Diseases'}, {'id': 'D005128', 'term': 'Eye Diseases'}]}}, 'protocolSection': {'designModule': {'studyType': 'OBSERVATIONAL', 'designInfo': {'timePerspective': 'PROSPECTIVE', 'observationalModel': 'CASE_ONLY'}, 'enrollmentInfo': {'type': 'ACTUAL', 'count': 98}, 'targetDuration': '14 Days', 'patientRegistry': True}, 'statusModule': {'overallStatus': 'COMPLETED', 'startDateStruct': {'date': '2011-01'}, 'expandedAccessInfo': {'hasExpandedAccess': False}, 'statusVerifiedDate': '2013-04', 'completionDateStruct': {'date': '2012-02', 'type': 'ACTUAL'}, 'lastUpdateSubmitDate': '2013-04-17', 'studyFirstSubmitDate': '2013-04-12', 'studyFirstSubmitQcDate': '2013-04-17', 'lastUpdatePostDateStruct': {'date': '2013-04-22', 'type': 'ESTIMATED'}, 'studyFirstPostDateStruct': {'date': '2013-04-22', 'type': 'ESTIMATED'}, 'primaryCompletionDateStruct': {'date': '2012-02', 'type': 'ACTUAL'}}, 'outcomesModule': {'otherOutcomes': [{'measure': 'location of inflammation and fundus finding', 'timeFrame': 'at baseline', 'description': 'location of inflammation\n\n* anterior or posterior or panuveitis\n\nfundus finding\n\n* granuloma in macular or periphery retina\n* pigmentation'}, {'measure': 'Demographic characteristics', 'timeFrame': 'at baseline', 'description': '* Gender\n* Residence\n* Pet ownership\n* Habit of eating uncooked meat'}], 'primaryOutcomes': [{'measure': 'Number of patients with positive result for serum antibody to Toxoplasma gondii and Toxocara canis', 'timeFrame': 'at baseline', 'description': 'proportion of patients with seropositive for Toxoplasma gondii and Toxocara canis among patients'}], 'secondaryOutcomes': [{'measure': 'Number of patients with positive PCR with peripheral blood and aqueous humor to Toxoplasma gondii and Toxocara canis', 'timeFrame': 'at baseline', 'description': 'Proportion of patient with positive PCR to Toxoplasma gondii and Toxocara canis'}]}, 'oversightModule': {'oversightHasDmc': True}, 'conditionsModule': {'keywords': ['Toxoplasma gondii', 'Toxocara canis'], 'conditions': ['Uveitis']}, 'descriptionModule': {'briefSummary': 'Investigate the prevalence of Toxoplasma gondii and Toxocara canis in Uveitis\n\n* serum antibody to T. gondii and T. canis\n* PCR with peripheral blood for T. gondii and T. canis\n* PCR with aqueous humor for T. gondii and T. canis\n* Clinical manifestation of patient with uveitis', 'detailedDescription': 'Consecutive patients with uveitis are enrolled in Nune Eye Hospital.\n\nSerum ELISA\n\n* IgM,IgG antibody to Toxoplasma gondii\n* IgG antibody to Toxocara canis\n\nPCR\n\n* PCR with serum and aqueous humor to Toxoplasma gondii\n* PCR with serum and aqueous humor to Toxocara canis Clinical characteristics\n* visual acuity\n* intraocular pressure (IOP)\n* location and degree of inflammation\n* other fundus findings were recorded\n\nquestionnaire\n\n* environment, occupation\n* pet ownership, exposure to animal\n* history of eating raw liver of animal, raw beef or any other raw flesh of animal.'}, 'eligibilityModule': {'sex': 'ALL', 'stdAges': ['CHILD', 'ADULT', 'OLDER_ADULT'], 'samplingMethod': 'PROBABILITY_SAMPLE', 'studyPopulation': 'patient with uveitis', 'healthyVolunteers': False, 'eligibilityCriteria': 'Inclusion Criteria:\n\n* patients with uveitis\n\nExclusion Criteria:\n\n* Patients with history of major ophthalmic surgery within 6 months\n* antiviral, antifungal or antiparasitic therapy within 6 months'}, 'identificationModule': {'nctId': 'NCT01837056', 'briefTitle': 'Prevalence of Toxoplasma Gondii and Toxocara Canis Among Patients With Uveitis', 'organization': {'class': 'OTHER_GOV', 'fullName': 'National Institute of Health, Korea'}, 'officialTitle': 'Prevalence of Toxoplasma Gondii and Toxocara Canis Among Patients With Uveitis', 'orgStudyIdInfo': {'id': 'Nuneuveitis'}}, 'contactsLocationsModule': {'overallOfficials': [{'name': 'Su Jin Lim, MD', 'role': 'PRINCIPAL_INVESTIGATOR', 'affiliation': 'Nune Eye Hospital'}]}, 'sponsorCollaboratorsModule': {'leadSponsor': {'name': 'National Institute of Health, Korea', 'class': 'OTHER_GOV'}, 'responsibleParty': {'type': 'PRINCIPAL_INVESTIGATOR', 'investigatorTitle': 'The retina staff', 'investigatorFullName': 'Lim, Su Jin', 'investigatorAffiliation': 'Nune Eye Hospital, Seoul, Korea'}}}}