Ignite Creation Date:
2025-12-24 @ 11:28 PM
Ignite Modification Date:
2026-02-21 @ 9:59 PM
Study NCT ID:
NCT05958056
Status:
COMPLETED
Last Update Posted:
2023-08-16
First Post:
2023-07-14
Is NOT Gene Therapy:
True
Has Adverse Events:
False
Brief Title:
Low Load Resistance Exercises With Blood Flow Restriction Versus High Load Resistance Exercises
Sponsor:
Organization:
Raw JSON
{'hasResults': False, 'derivedSection': {'miscInfoModule': {'versionHolder': '2025-12-24'}, 'interventionBrowseModule': {'meshes': [{'id': 'D055070', 'term': 'Resistance Training'}], 'ancestors': [{'id': 'D005081', 'term': 'Exercise Therapy'}, {'id': 'D012046', 'term': 'Rehabilitation'}, {'id': 'D000359', 'term': 'Aftercare'}, {'id': 'D003266', 'term': 'Continuity of Patient Care'}, {'id': 'D005791', 'term': 'Patient Care'}, {'id': 'D013812', 'term': 'Therapeutics'}, {'id': 'D026741', 'term': 'Physical Therapy Modalities'}, {'id': 'D064797', 'term': 'Physical Conditioning, Human'}, {'id': 'D015444', 'term': 'Exercise'}, {'id': 'D009043', 'term': 'Motor Activity'}, {'id': 'D009068', 'term': 'Movement'}, {'id': 'D009142', 'term': 'Musculoskeletal Physiological Phenomena'}, {'id': 'D055687', 'term': 'Musculoskeletal and Neural Physiological Phenomena'}]}}, 'protocolSection': {'designModule': {'phases': ['NA'], 'studyType': 'INTERVENTIONAL', 'designInfo': {'allocation': 'NON_RANDOMIZED', 'maskingInfo': {'masking': 'NONE'}, 'primaryPurpose': 'SCREENING', 'interventionModel': 'PARALLEL'}, 'enrollmentInfo': {'type': 'ACTUAL', 'count': 22}}, 'statusModule': {'overallStatus': 'COMPLETED', 'startDateStruct': {'date': '2021-03-01', 'type': 'ACTUAL'}, 'expandedAccessInfo': {'hasExpandedAccess': False}, 'statusVerifiedDate': '2023-08', 'completionDateStruct': {'date': '2022-07-01', 'type': 'ACTUAL'}, 'lastUpdateSubmitDate': '2023-08-15', 'studyFirstSubmitDate': '2023-07-14', 'studyFirstSubmitQcDate': '2023-07-14', 'lastUpdatePostDateStruct': {'date': '2023-08-16', 'type': 'ACTUAL'}, 'studyFirstPostDateStruct': {'date': '2023-07-24', 'type': 'ACTUAL'}, 'primaryCompletionDateStruct': {'date': '2021-12-01', 'type': 'ACTUAL'}}, 'outcomesModule': {'primaryOutcomes': [{'measure': 'Growth Hormone', 'timeFrame': 'Before intervention.', 'description': 'Blood test of the level of growth hormone'}, {'measure': 'Growth Hormone', 'timeFrame': 'Immediately post intervention.', 'description': 'Blood test of the level of growth hormone'}, {'measure': 'Growth Hormone', 'timeFrame': '15 minutes after the end of intervention.', 'description': 'Blood test of the level of growth hormone'}, {'measure': 'Blood lactate', 'timeFrame': 'Before intervention.', 'description': 'Blood test of the level of Blood lactate'}, {'measure': 'Blood lactate', 'timeFrame': 'Immediately post intervention.', 'description': 'Blood test of the level of Blood lactate'}, {'measure': 'Blood lactate', 'timeFrame': '15 minutes after the end of intervention.', 'description': 'Blood test of the level of Blood lactate'}]}, 'oversightModule': {'oversightHasDmc': False, 'isFdaRegulatedDrug': False, 'isFdaRegulatedDevice': False}, 'conditionsModule': {'keywords': ['blood flow restriction', 'Growth hormone', 'Blood lactate'], 'conditions': ['Athletes']}, 'descriptionModule': {'briefSummary': 'Practical blood flow restriction (PBFR) is a new technique of reducing the venous return using a band with a pressure that is applied using a perceived pressure scale. The studies that investigate the acute effect of using PBFR and regular high intensity exercises on the level of growth hormone (GH) and blood lactate (BL) after lower extremity training in collegiate athletes are scarce.', 'detailedDescription': 'Practical blood flow restriction (PBFR) is a new technique of reducing the venous return using a band with a pressure that is applied using a perceived pressure scale. The studies that investigate the acute effect of using PBFR and regular high intensity exercises on the level of growth hormone (GH) and blood lactate (BL) after lower extremity training in collegiate athletes are scarce. Therefore, this study aimed to investigate the acute effect of a single session low load resistance exercises with PBFR compared to a high load resistance exercises without PBFR on the levels of GH and BL. A convenience sample of collegiate athletes were allocated to either an experimental group that performed low resistance exercises with PBFR or a control group that performed high resistance exercises without PBFR. The levels of GH and BL were examined in 3 time points: pre-training, immediate post-training, and 15 minutes post-training for both groups. Analysis of Variance (ANOVA) was used to assess the main and interaction effects of the groups.'}, 'eligibilityModule': {'sex': 'MALE', 'stdAges': ['ADULT'], 'maximumAge': '60 Years', 'minimumAge': '18 Years', 'healthyVolunteers': True, 'eligibilityCriteria': 'Inclusion Criteria:\n\n* Student collegiate athletes.\n* Age of 18 years and older.\n* Free from any cardiovascular or respiratory disorders and did not have any injuries during the previous 12 months.\n\nExclusion Criteria:\n\n* Students who were taking any medications for chronic conditions.\n* Student who were taking any supplements.'}, 'identificationModule': {'nctId': 'NCT05958056', 'briefTitle': 'Low Load Resistance Exercises With Blood Flow Restriction Versus High Load Resistance Exercises', 'organization': {'class': 'OTHER', 'fullName': 'University of Jordan'}, 'officialTitle': 'The Acute Effect of Low Load Resistance Exercises With Blood Flow Restriction Versus High Load Resistance Exercises on Growth Hormone and Blood Lactate', 'orgStudyIdInfo': {'id': '4/2019'}}, 'armsInterventionsModule': {'armGroups': [{'type': 'EXPERIMENTAL', 'label': 'Low load resistance exercises with Practical blood flow restriction (PBFR)', 'description': 'Participants in the experimental group performed one session of 30% 1RM with Practical blood flow restriction training. The number of repetitions in every set was 15 times with PBFR.19 Participants in the experimental group used the elite band (occlusion training bands) for both thighs during the training session. The width of the thigh band was 5cm, which would produce a pressure between 160-240 mmHg. This pressure range is appropriate for most of the individuals who used PBFR.27 The perceived pressure scale (PPS) was used to estimate the appropriate pressure (7 out of 10) in training before performing the exercises.28,29 The blood flow restriction bands booklet was used30 along with previous studies to design the training session. Participants removed the BFR band immediately after the end of the training session.', 'interventionNames': ['Other: Resistance exercise']}, {'type': 'ACTIVE_COMPARATOR', 'label': 'High resistance exercises', 'description': 'Participants in the control group performed one session of 80% 1RM without PBFR. The number of repetitions in every set was 10 times.', 'interventionNames': ['Other: Resistance exercise']}], 'interventions': [{'name': 'Resistance exercise', 'type': 'OTHER', 'description': 'The training session included leg curl and leg extension exercises with 4 sets each. Participants started with leg extension exercise for 4 sets with a 30-second rest periods between the sets. Then, participants took a rest for 60 seconds. Afterward, participants performed leg curl exercise for 4 sets with a 30-second rest periods between the sets. Exercises in each set were performed continuously (uninterrupted) with a speed of 2 seconds for each repetition and a medium exercise performance speed.', 'armGroupLabels': ['High resistance exercises', 'Low load resistance exercises with Practical blood flow restriction (PBFR)']}]}, 'contactsLocationsModule': {'locations': [{'zip': '11942', 'city': 'Amman', 'country': 'Jordan', 'facility': 'The University of Jordan', 'geoPoint': {'lat': 31.95522, 'lon': 35.94503}}], 'overallOfficials': [{'name': 'Alia Alghwiri, PhD', 'role': 'STUDY_DIRECTOR', 'affiliation': 'The University of Jordan'}]}, 'ipdSharingStatementModule': {'ipdSharing': 'NO'}, 'sponsorCollaboratorsModule': {'leadSponsor': {'name': 'University of Jordan', 'class': 'OTHER'}, 'collaborators': [{'name': 'The Hashemite University', 'class': 'OTHER'}], 'responsibleParty': {'type': 'PRINCIPAL_INVESTIGATOR', 'investigatorTitle': 'Professor', 'investigatorFullName': 'Alia A. Alghwiri', 'investigatorAffiliation': 'University of Jordan'}}}}