Ignite Creation Date:
2025-12-24 @ 11:17 PM
Ignite Modification Date:
2026-02-26 @ 8:12 PM
Study NCT ID:
NCT00196456
Status:
COMPLETED
Last Update Posted:
2005-09-20
First Post:
2005-09-12
Is NOT Gene Therapy:
True
Has Adverse Events:
False
Brief Title:
Photodynamic Lasertherapy (PDT) in Periodontal Treatment (in Vivo)
Sponsor:
Organization:
Raw JSON
{'hasResults': False, 'derivedSection': {'miscInfoModule': {'versionHolder': '2025-12-24'}, 'conditionBrowseModule': {'meshes': [{'id': 'D010510', 'term': 'Periodontal Diseases'}], 'ancestors': [{'id': 'D009059', 'term': 'Mouth Diseases'}, {'id': 'D009057', 'term': 'Stomatognathic Diseases'}]}}, 'protocolSection': {'designModule': {'phases': ['PHASE2'], 'studyType': 'INTERVENTIONAL', 'designInfo': {'allocation': 'RANDOMIZED', 'maskingInfo': {'masking': 'DOUBLE'}, 'primaryPurpose': 'TREATMENT', 'interventionModel': 'PARALLEL'}, 'enrollmentInfo': {'count': 60}}, 'statusModule': {'overallStatus': 'COMPLETED', 'startDateStruct': {'date': '2004-04'}, 'expandedAccessInfo': {'hasExpandedAccess': False}, 'statusVerifiedDate': '2005-09', 'completionDateStruct': {'date': '2005-01'}, 'lastUpdateSubmitDate': '2005-09-12', 'studyFirstSubmitDate': '2005-09-12', 'studyFirstSubmitQcDate': '2005-09-12', 'lastUpdatePostDateStruct': {'date': '2005-09-20', 'type': 'ESTIMATED'}, 'studyFirstPostDateStruct': {'date': '2005-09-20', 'type': 'ESTIMATED'}}, 'outcomesModule': {'primaryOutcomes': [{'measure': 'pocket depth reduction'}], 'secondaryOutcomes': [{'measure': 'attachmentlevel loss'}]}, 'conditionsModule': {'keywords': ['Photodynamic lasertherapy', 'Periodontol disease'], 'conditions': ['Periodontal Disease']}, 'referencesModule': {'references': [{'pmid': '11107854', 'type': 'BACKGROUND', 'citation': 'Komerik N, Wilson M, Poole S. The effect of photodynamic action on two virulence factors of gram-negative bacteria. Photochem Photobiol. 2000 Nov;72(5):676-80. doi: 10.1562/0031-8655(2000)0722.0.co;2.'}]}, 'descriptionModule': {'briefSummary': 'The purpose of the study is to evaluate the effect of the photodynamic therapy in periodontal patients', 'detailedDescription': 'The purpose of the study is to evaluate the effect of the photodynamic therapy in periodontal pockets and to assess the reduction of subgingival bacteria.\n\nThe first step will include the evaluation of the quantity of the light which will activate the photosensitizer in the various niches in the periodontal pocket.\n\nThe second step will evaluate the distribution of the photosensitizer in the periodontal pocket.\n\nThe third step will assess the woundhealing of the the photodynamic therapy compared to conventional periodontal therapy with an ultrasonic device.'}, 'eligibilityModule': {'sex': 'ALL', 'stdAges': ['ADULT', 'OLDER_ADULT'], 'minimumAge': '35 Years', 'healthyVolunteers': True, 'eligibilityCriteria': 'Inclusion Criteria:\n\n* systemic healthy\n* \\>15 teeth\n* ≤ 6 mm \\>2 teeth\n* age \\> 35 years\n\nExclusion Criteria:\n\n* \\- systemic ill\n* cardiac pacemaker\n* \\< 15 teeth'}, 'identificationModule': {'nctId': 'NCT00196456', 'briefTitle': 'Photodynamic Lasertherapy (PDT) in Periodontal Treatment (in Vivo)', 'organization': {'class': 'OTHER', 'fullName': 'University Medicine Greifswald'}, 'officialTitle': 'Photodynamic Lasertherapy (PDT) in Periodontal Treatment (in Vivo)', 'orgStudyIdInfo': {'id': 'III UV 06/04'}}, 'armsInterventionsModule': {'interventions': [{'name': 'photosensitisation', 'type': 'PROCEDURE'}]}, 'contactsLocationsModule': {'locations': [{'zip': '17489', 'city': 'Greifswald', 'state': 'Mecklenburg-Vorpommern', 'country': 'Germany', 'facility': 'Ernst-Moritz-Arndt-Universität Greifswald', 'geoPoint': {'lat': 54.08905, 'lon': 13.40244}}], 'overallOfficials': [{'name': 'Thomas Kocher, Prof.Dr.', 'role': 'PRINCIPAL_INVESTIGATOR', 'affiliation': 'Ernst-Moritz-Arndt University Greifswald'}]}, 'sponsorCollaboratorsModule': {'leadSponsor': {'name': 'University Medicine Greifswald', 'class': 'OTHER'}}}}