Ignite Creation Date:
2025-12-24 @ 11:16 PM
Ignite Modification Date:
2026-01-01 @ 11:48 AM
Study NCT ID:
NCT05244356
Status:
COMPLETED
Last Update Posted:
2022-02-17
First Post:
2022-02-10
Is NOT Gene Therapy:
True
Has Adverse Events:
False
Brief Title:
Health Communication to Influence COVID-19 Vaccination Intent and Message Propagation
Sponsor:
Organization:
Raw JSON
{'hasResults': False, 'derivedSection': {'miscInfoModule': {'versionHolder': '2025-12-24'}, 'conditionBrowseModule': {'meshes': [{'id': 'D000086382', 'term': 'COVID-19'}, {'id': 'D012120', 'term': 'Respiration Disorders'}, {'id': 'D000072758', 'term': 'Vaccination Refusal'}, {'id': 'D003141', 'term': 'Communicable Diseases'}, {'id': 'D018352', 'term': 'Coronavirus Infections'}, {'id': 'D015438', 'term': 'Health Behavior'}, {'id': 'D011014', 'term': 'Pneumonia'}, {'id': 'D012141', 'term': 'Respiratory Tract Infections'}, {'id': 'D008171', 'term': 'Lung Diseases'}, {'id': 'D011024', 'term': 'Pneumonia, Viral'}], 'ancestors': [{'id': 'D007239', 'term': 'Infections'}, {'id': 'D014777', 'term': 'Virus Diseases'}, {'id': 'D003333', 'term': 'Coronaviridae Infections'}, {'id': 'D030341', 'term': 'Nidovirales Infections'}, {'id': 'D012327', 'term': 'RNA Virus Infections'}, {'id': 'D012140', 'term': 'Respiratory Tract Diseases'}, {'id': 'D016312', 'term': 'Treatment Refusal'}, {'id': 'D000074822', 'term': 'Treatment Adherence and Compliance'}, {'id': 'D001519', 'term': 'Behavior'}, {'id': 'D020969', 'term': 'Disease Attributes'}, {'id': 'D010335', 'term': 'Pathologic Processes'}, {'id': 'D013568', 'term': 'Pathological Conditions, Signs and Symptoms'}]}}, 'protocolSection': {'designModule': {'phases': ['NA'], 'studyType': 'INTERVENTIONAL', 'designInfo': {'allocation': 'RANDOMIZED', 'maskingInfo': {'masking': 'SINGLE', 'whoMasked': ['PARTICIPANT']}, 'primaryPurpose': 'OTHER', 'interventionModel': 'PARALLEL'}, 'enrollmentInfo': {'type': 'ACTUAL', 'count': 5784}}, 'statusModule': {'overallStatus': 'COMPLETED', 'startDateStruct': {'date': '2021-04-29', 'type': 'ACTUAL'}, 'expandedAccessInfo': {'hasExpandedAccess': False}, 'statusVerifiedDate': '2022-02', 'completionDateStruct': {'date': '2021-06-07', 'type': 'ACTUAL'}, 'lastUpdateSubmitDate': '2022-02-16', 'studyFirstSubmitDate': '2022-02-10', 'studyFirstSubmitQcDate': '2022-02-16', 'lastUpdatePostDateStruct': {'date': '2022-02-17', 'type': 'ACTUAL'}, 'studyFirstPostDateStruct': {'date': '2022-02-17', 'type': 'ACTUAL'}, 'primaryCompletionDateStruct': {'date': '2021-06-07', 'type': 'ACTUAL'}}, 'outcomesModule': {'primaryOutcomes': [{'measure': 'Change in intent to accept the COVID-19 vaccine amongst the Malaysian adult population.', 'timeFrame': 'Immediately before and after message exposure during questionnaire administration.', 'description': 'Outcome measure was assessed using a questionnaire answered through a 4 point ordinal scale. Scale ranges from \'"Definitely no", "Not sure, but probably no", "Not sure, but probably yes"to Definitely yes".'}, {'measure': 'Change in intent to recommend the COVID-19 vaccine to healthy adults.', 'timeFrame': 'Immediately before and after message exposure during questionnaire administration.', 'description': 'Outcome measure was assessed using a questionnaire answered through a 5 point ordinal scale. Scale ranges from "Strongly disagree", "Disagree", "Not sure", "Agree", and "Strongly agree".'}, {'measure': 'Change in intent to recommend the COVID-19 vaccine to elderly.', 'timeFrame': 'Immediately before and after message exposure during questionnaire administration.', 'description': 'Outcome measure was assessed using a questionnaire answered through a 5 point ordinal scale. Scale ranges from "Strongly disagree", "Disagree", "Not sure", "Agree", and "Strongly agree".'}, {'measure': 'Change in intent to recommend the COVID-19 vaccine to people with existing health conditions.', 'timeFrame': 'Immediately before and after message exposure during questionnaire administration.', 'description': 'Outcome measure was assessed using a questionnaire answered through a 5 point ordinal scale. Scale ranges from "Strongly disagree", "Disagree", "Not sure", "Agree", and "Strongly agree".'}, {'measure': 'Intent to share message on social media platform.', 'timeFrame': 'Immediately after message exposure during questionnaire administration.', 'description': 'Outcome measure was assessed using a questionnaire answered through a 5 point ordinal scale.Scale ranges from "Strongly disagree", "Disagree", "Not sure", "Agree", and "Strongly agree".'}], 'secondaryOutcomes': [{'measure': 'Moderators of vaccination intent.', 'timeFrame': 'Immediately after message exposure during questionnaire administration.', 'description': 'Outcome measure assessed using a series of questions answered through a 5 point ordinal scale. Scale ranges from "Strongly disagree", "Disagree", "Not sure", "Agree", and "Strongly agree".'}, {'measure': 'Reliability of various information sources about COVID-19.', 'timeFrame': 'Immediately after message exposure during questionnaire administration.', 'description': 'Outcome measure assessed using a questionnaire that list out various types of information sources and having participants to rate the reliability for each source using a 5 point ordinal scale. Scale ranges from "Strongly not reliable", "Not reliable, "Not sure", "Reliable", and "Strongly reliable".'}]}, 'oversightModule': {'oversightHasDmc': False, 'isFdaRegulatedDrug': False, 'isFdaRegulatedDevice': False}, 'conditionsModule': {'keywords': ['message', 'messaging', 'propagation', 'intent', 'vaccine', 'recommend'], 'conditions': ['COVID-19', 'Respiratory Disease', 'Vaccine Refusal', 'Infectious Disease', 'Coronavirus Infections', 'Behavior, Health', 'Pneumonia', 'Respiratory Tract Infections', 'Lung Diseases', 'Pneumonia, Viral']}, 'referencesModule': {'references': [{'pmid': '35906015', 'type': 'DERIVED', 'citation': 'Hing NYL, Woon YL, Lee YK, Kim HJ, Lothfi NM, Wong E, Perialathan K, Ahmad Sanusi NH, Isa A, Leong CT, Costa-Font J. When do persuasive messages on vaccine safety steer COVID-19 vaccine acceptance and recommendations? Behavioural insights from a randomised controlled experiment in Malaysia. BMJ Glob Health. 2022 Jul;7(7):e009250. doi: 10.1136/bmjgh-2022-009250.'}]}, 'descriptionModule': {'briefSummary': 'This is a randomised controlled experiment in the form of a web based survey study which randomly exposes participants to different forms of public health messages, after which participants will be assessed on their intent to take up the COVID-19 vaccine, recommend the vaccine, and also willingness to propagate the exposed message.'}, 'eligibilityModule': {'sex': 'ALL', 'stdAges': ['ADULT', 'OLDER_ADULT'], 'minimumAge': '18 Years', 'healthyVolunteers': True, 'eligibilityCriteria': 'Inclusion Criteria:\n\n* Willing and able to give informed consent for participation in the trial\n* Malaysian nationality.\n* Can understand either the English or Malay language.\n* Aged 18 years or above\n\nExclusion Criteria:\n\n* Received at least one COVID-19 vaccination dose'}, 'identificationModule': {'nctId': 'NCT05244356', 'acronym': 'CONVINCE', 'briefTitle': 'Health Communication to Influence COVID-19 Vaccination Intent and Message Propagation', 'organization': {'class': 'OTHER', 'fullName': 'Clinical Research Centre, Malaysia'}, 'officialTitle': 'Effective Public Health Communication to Influence COVID-19 Vaccination Intent and Message Propagation: A Randomized Controlled Experiment', 'orgStudyIdInfo': {'id': 'NMRR-21-26-58107'}}, 'armsInterventionsModule': {'armGroups': [{'type': 'EXPERIMENTAL', 'label': 'Descriptive Norm (70%)', 'description': 'Intervention in the form of a message likened to a social media post. Composed of 3 parts:\n\n1. Opening tag line highlighting the main concern that Malaysians have about the COVID-19 vaccine (safety and side effects)\n2. Message content describing that about 70% of Malaysians have expressed acceptance for the COVID-19 vaccine.\n3. Rally slogan: "It\'s safe and effective!"', 'interventionNames': ['Behavioral: Health message exposure']}, {'type': 'EXPERIMENTAL', 'label': 'Descriptive Norm', 'description': 'Intervention in the form of a message likened to a social media post. Composed of 3 parts:\n\n1. Opening tag line highlighting the main concern that Malaysians have about the COVID-19 vaccine (safety and side effects)\n2. Message content describing that the COVID-19 vaccine has been widely tested including with the elderly and people with existing health conditions, while subsequently highlighting that the vaccine was already received by millions worldwide.\n3. Rally slogan: "It\'s safe and effective!"', 'interventionNames': ['Behavioral: Health message exposure']}, {'type': 'EXPERIMENTAL', 'label': 'Healthcare worker (HCW) recommendation', 'description': 'Intervention in the form of a message likened to a social media post. Composed of 3 parts:\n\n1. Opening tag line highlighting the main concern that Malaysians have about the COVID-19 vaccine (safety and side effects)\n2. Message content highlights recommendation from Malaysian healthcare workers to get the vaccine, since majority of them has already received it, including the Malaysian Health Director General\n3. Rally slogan: "It\'s safe and effective!"', 'interventionNames': ['Behavioral: Health message exposure']}, {'type': 'EXPERIMENTAL', 'label': 'Negative attribute framing', 'description': 'Intervention in the form of a message likened to a social media post. Composed of 3 parts:\n\n1. Opening tag line highlighting the main concern that Malaysians have about the COVID-19 vaccine (safety and side effects)\n2. Message content describing the rate of side effects occurring with COVID-19 vaccination in a negative frame.\n3. Rally slogan: "It\'s safe and effective!"', 'interventionNames': ['Behavioral: Health message exposure']}, {'type': 'EXPERIMENTAL', 'label': 'Positive attribute framing', 'description': 'Intervention in the form of a message likened to a social media post. Composed of 3 parts:\n\n1. Opening tag line highlighting the main concern that Malaysians have about the COVID-19 vaccine (safety and side effects)\n2. Message content describing the rate of side effects occurring with COVID-19 vaccination in a positive frame.\n3. Rally slogan: "It\'s safe and effective!"', 'interventionNames': ['Behavioral: Health message exposure']}, {'type': 'EXPERIMENTAL', 'label': 'Risky choice framing (Safety)', 'description': 'Intervention in the form of a message likened to a social media post. Composed of 3 parts:\n\n1. Opening tag line highlighting the main concern that Malaysians have about the COVID-19 vaccine (safety and side effects)\n2. Message content describing a risky choice frame which compares the death rates occurring with COVID-19 vaccination versus contracting the virus itself.\n3. Rally slogan: "It\'s safe and effective!"', 'interventionNames': ['Behavioral: Health message exposure']}, {'type': 'EXPERIMENTAL', 'label': 'Risky choice framing (Side effects)', 'description': 'Intervention in the form of a message likened to a social media post. Composed of 3 parts:\n\n1. Opening tag line highlighting the main concern that Malaysians have about the COVID-19 vaccine (safety and side effects)\n2. Message content describing a risky choice frame that compares the incidence rates of blood clots occurring with COVID-19 vaccination versus contracting COVID-19.\n3. Rally slogan: "It\'s safe and effective!"', 'interventionNames': ['Behavioral: Health message exposure']}, {'type': 'EXPERIMENTAL', 'label': 'Control message', 'description': 'Control message containing only rally slogan: "It\'s safe and effective!"', 'interventionNames': ['Behavioral: Health message exposure']}, {'type': 'EXPERIMENTAL', 'label': 'Combination message: Descriptive Norm (70%) + Descriptive Norm', 'description': 'Participants received 2 messages which were exposed one at a time. Sequence of message appearing randomly rotated.', 'interventionNames': ['Behavioral: Health message exposure']}, {'type': 'EXPERIMENTAL', 'label': 'Combination message: Descriptive Norm (70%) + HCW recommendation', 'description': 'Participants received 2 messages which were exposed one at a time. Sequence of message appearing randomly rotated.', 'interventionNames': ['Behavioral: Health message exposure']}, {'type': 'EXPERIMENTAL', 'label': 'Combination message: Descriptive Norm (70%) + Negative attribute framing', 'description': 'Participants received 2 messages which were exposed one at a time. Sequence of message appearing randomly rotated.', 'interventionNames': ['Behavioral: Health message exposure']}, {'type': 'EXPERIMENTAL', 'label': 'Combination message: Descriptive Norm (70%) + Positive attribute framing', 'description': 'Participants received 2 messages which were exposed one at a time. Sequence of message appearing randomly rotated.', 'interventionNames': ['Behavioral: Health message exposure']}, {'type': 'EXPERIMENTAL', 'label': 'Combination message: Descriptive Norm (70%) + Risky choice framing (Safety)', 'description': 'Participants received 2 messages which were exposed one at a time. Sequence of message appearing randomly rotated.', 'interventionNames': ['Behavioral: Health message exposure']}, {'type': 'EXPERIMENTAL', 'label': 'Combination message: Descriptive Norm (70%) + Risky choice framing (Side effects)', 'description': 'Participants received 2 messages which were exposed one at a time. Sequence of message appearing randomly rotated.', 'interventionNames': ['Behavioral: Health message exposure']}], 'interventions': [{'name': 'Health message exposure', 'type': 'BEHAVIORAL', 'description': 'Participants exposed to a health message and requested to read it completely. Subsequently requested to answer post intervention questions that form basis for outcome measures.', 'armGroupLabels': ['Combination message: Descriptive Norm (70%) + Descriptive Norm', 'Combination message: Descriptive Norm (70%) + HCW recommendation', 'Combination message: Descriptive Norm (70%) + Negative attribute framing', 'Combination message: Descriptive Norm (70%) + Positive attribute framing', 'Combination message: Descriptive Norm (70%) + Risky choice framing (Safety)', 'Combination message: Descriptive Norm (70%) + Risky choice framing (Side effects)', 'Control message', 'Descriptive Norm', 'Descriptive Norm (70%)', 'Healthcare worker (HCW) recommendation', 'Negative attribute framing', 'Positive attribute framing', 'Risky choice framing (Safety)', 'Risky choice framing (Side effects)']}]}, 'contactsLocationsModule': {'locations': [{'zip': '40170', 'city': 'Shah Alam', 'state': 'Selangor', 'country': 'Malaysia', 'facility': 'Institute for Clinical Research, National Institutes of Health, Malaysia', 'geoPoint': {'lat': 3.08507, 'lon': 101.53281}}], 'overallOfficials': [{'name': 'Yee Liang Hing, MSc.', 'role': 'PRINCIPAL_INVESTIGATOR', 'affiliation': 'Clinical Research Centre, Malaysia'}]}, 'ipdSharingStatementModule': {'ipdSharing': 'NO'}, 'sponsorCollaboratorsModule': {'leadSponsor': {'name': 'Clinical Research Centre, Malaysia', 'class': 'OTHER'}, 'collaborators': [{'name': 'Institute for Health Behavioral Research, Malaysia', 'class': 'UNKNOWN'}, {'name': 'University of Malaya', 'class': 'OTHER'}, {'name': 'UNICEF Malaysia', 'class': 'UNKNOWN'}, {'name': 'Ministry of Health, Malaysia', 'class': 'OTHER_GOV'}, {'name': 'London School of Economics and Political Science', 'class': 'OTHER'}], 'responsibleParty': {'type': 'PRINCIPAL_INVESTIGATOR', 'investigatorTitle': 'Researcher, Principle Investigator, Pharmacist', 'investigatorFullName': 'Nicholas Hing Yee Liang', 'investigatorAffiliation': 'Clinical Research Centre, Malaysia'}}}}