Ignite Creation Date:
2025-12-24 @ 11:03 PM
Ignite Modification Date:
2026-03-04 @ 9:54 PM
Study NCT ID:
NCT00470769
Status:
UNKNOWN
Last Update Posted:
2007-05-08
First Post:
2007-05-07
Is NOT Gene Therapy:
True
Has Adverse Events:
False
Brief Title:
The Efficacy of Color-Doppler Ultrasonography to Assess the Renal Blood Flow With the Estimation of GFR
Sponsor:
Organization:
Raw JSON
{'hasResults': False, 'derivedSection': {'miscInfoModule': {'versionHolder': '2025-12-24'}, 'conditionBrowseModule': {'meshes': [{'id': 'D006973', 'term': 'Hypertension'}, {'id': 'D051437', 'term': 'Renal Insufficiency'}], 'ancestors': [{'id': 'D014652', 'term': 'Vascular Diseases'}, {'id': 'D002318', 'term': 'Cardiovascular Diseases'}, {'id': 'D007674', 'term': 'Kidney Diseases'}, {'id': 'D014570', 'term': 'Urologic Diseases'}, {'id': 'D052776', 'term': 'Female Urogenital Diseases'}, {'id': 'D005261', 'term': 'Female Urogenital Diseases and Pregnancy Complications'}, {'id': 'D000091642', 'term': 'Urogenital Diseases'}, {'id': 'D052801', 'term': 'Male Urogenital Diseases'}]}}, 'protocolSection': {'designModule': {'studyType': 'OBSERVATIONAL', 'designInfo': {'timePerspective': 'OTHER', 'observationalModel': 'DEFINED_POPULATION'}, 'enrollmentInfo': {'type': 'ESTIMATED', 'count': 2006}}, 'statusModule': {'overallStatus': 'UNKNOWN', 'lastKnownStatus': 'RECRUITING', 'startDateStruct': {'date': '2006-09'}, 'expandedAccessInfo': {'hasExpandedAccess': False}, 'statusVerifiedDate': '2007-05', 'completionDateStruct': {'date': '2007-05', 'type': 'ESTIMATED'}, 'lastUpdateSubmitDate': '2007-05-07', 'studyFirstSubmitDate': '2007-05-07', 'studyFirstSubmitQcDate': '2007-05-07', 'lastUpdatePostDateStruct': {'date': '2007-05-08', 'type': 'ESTIMATED'}, 'studyFirstPostDateStruct': {'date': '2007-05-08', 'type': 'ESTIMATED'}}, 'oversightModule': {'oversightHasDmc': False}, 'conditionsModule': {'keywords': ['Color-Doppler Ultrasonography', 'Renal scintigraphy', 'Kidney failure', 'GFR'], 'conditions': ['Hypertension', 'Renal Failure']}, 'descriptionModule': {'briefSummary': 'It is generally assumed that renal blood flow is symmetric in the absence of renal artery stenosis. The importance of studying the function of both kidneys separately is because it cannot be assumed that they are functionally equal.The aim of the present study is to evaluate whether this is really in patients with essential hypertension and/or moderate kidneys loss.', 'detailedDescription': 'To validate color Doppler ultrasonography of renal arteries for the assessment of renal blood flow (RBF), we comparing left and right RBF estimates and their sum (total RBF) by echo-Doppler with data obtained by 99mTc-DTPA scintigraphy in 50 patients with hypertension and/or moderate renal failure, compared with 30 normal control subjects.'}, 'eligibilityModule': {'sex': 'ALL', 'stdAges': ['ADULT', 'OLDER_ADULT'], 'maximumAge': '80 Years', 'minimumAge': '30 Years', 'healthyVolunteers': True, 'eligibilityCriteria': 'Inclusion Criteria:\n\n* Patients with hypertension\n* Patients with moderate renal insufficiency\n* Normal subjects\n\nExclusion Criteria:\n\n* Patients with solitary kidney function\n* Patients with renal artery stenosis\n* Patients underwent renal angioplasty and stenting'}, 'identificationModule': {'nctId': 'NCT00470769', 'briefTitle': 'The Efficacy of Color-Doppler Ultrasonography to Assess the Renal Blood Flow With the Estimation of GFR', 'organization': {'class': 'OTHER', 'fullName': 'University of Roma La Sapienza'}, 'officialTitle': 'Color-Doppler Ultrasonography vs 99mTc-DTPA Scintigraphy to Assess the Renal Blood Flow', 'orgStudyIdInfo': {'id': 'CR-UR-00001'}}, 'armsInterventionsModule': {'interventions': [{'name': 'Color-Doppler Ultrasound, 99mTc-DTPA scintigraphy', 'type': 'PROCEDURE'}]}, 'contactsLocationsModule': {'locations': [{'zip': '88020', 'city': 'Catanzaro', 'status': 'RECRUITING', 'country': 'Italy', 'facility': 'Giorgio Fuiano', 'geoPoint': {'lat': 38.88247, 'lon': 16.60086}}, {'zip': '00100', 'city': 'Roma', 'status': 'RECRUITING', 'country': 'Italy', 'contacts': [{'name': 'Rosario Cianci, MD', 'role': 'CONTACT', 'email': 'ciancirosario@tin.it', 'phone': '+39335206441'}, {'name': 'Giorgio Fuiano, MD', 'role': 'CONTACT', 'email': 'gfuiano@libero.it', 'phone': '+39 0961775360'}], 'facility': 'University of Rome La Sapienza', 'geoPoint': {'lat': 44.99364, 'lon': 11.10642}}, {'zip': '00100', 'city': 'Rome', 'status': 'RECRUITING', 'country': 'Italy', 'facility': 'Rosario Cianci', 'geoPoint': {'lat': 41.89193, 'lon': 12.51133}}], 'centralContacts': [{'name': 'Rosario Cianci, MD', 'role': 'CONTACT', 'email': 'ciancirosario@tin.it', 'phone': '+39335206441'}], 'overallOfficials': [{'name': 'Rosario Cianci, MD', 'role': 'PRINCIPAL_INVESTIGATOR', 'affiliation': 'Department Of Clinic Medicine, Chair of Nephrology'}, {'name': 'Giorgio Fuiano, MD', 'role': 'STUDY_DIRECTOR', 'affiliation': 'University of Catanzaro'}]}, 'sponsorCollaboratorsModule': {'leadSponsor': {'name': 'University of Roma La Sapienza', 'class': 'OTHER'}}}}