Ignite Creation Date:
2025-12-24 @ 10:58 PM
Ignite Modification Date:
2026-01-05 @ 6:03 PM
Study NCT ID:
NCT03802669
Status:
COMPLETED
Last Update Posted:
2019-09-17
First Post:
2019-01-10
Is NOT Gene Therapy:
True
Has Adverse Events:
False
Brief Title:
Molecular Assessment of Oral Mutans Streptococcus Isolated From Different Patients
Sponsor:
Organization:
Raw JSON
{'hasResults': False, 'derivedSection': {'miscInfoModule': {'versionHolder': '2025-12-24'}, 'conditionBrowseModule': {'meshes': [{'id': 'D003731', 'term': 'Dental Caries'}], 'ancestors': [{'id': 'D017001', 'term': 'Tooth Demineralization'}, {'id': 'D014076', 'term': 'Tooth Diseases'}, {'id': 'D009057', 'term': 'Stomatognathic Diseases'}]}}, 'protocolSection': {'designModule': {'studyType': 'OBSERVATIONAL', 'designInfo': {'timePerspective': 'CROSS_SECTIONAL', 'observationalModel': 'CASE_CONTROL'}, 'enrollmentInfo': {'type': 'ACTUAL', 'count': 90}, 'patientRegistry': False}, 'statusModule': {'overallStatus': 'COMPLETED', 'startDateStruct': {'date': '2019-01-12', 'type': 'ACTUAL'}, 'expandedAccessInfo': {'hasExpandedAccess': False}, 'statusVerifiedDate': '2019-09', 'completionDateStruct': {'date': '2019-05-20', 'type': 'ACTUAL'}, 'lastUpdateSubmitDate': '2019-09-13', 'studyFirstSubmitDate': '2019-01-10', 'studyFirstSubmitQcDate': '2019-01-10', 'lastUpdatePostDateStruct': {'date': '2019-09-17', 'type': 'ACTUAL'}, 'studyFirstPostDateStruct': {'date': '2019-01-14', 'type': 'ACTUAL'}, 'primaryCompletionDateStruct': {'date': '2019-02-15', 'type': 'ACTUAL'}}, 'outcomesModule': {'primaryOutcomes': [{'measure': 'oral mutans streptococcus screening', 'timeFrame': 'immediately', 'description': 'screening of oral mutans streptococcus of each group to determine the differences'}]}, 'oversightModule': {'isFdaRegulatedDrug': False, 'isFdaRegulatedDevice': False}, 'conditionsModule': {'keywords': ['human saliva', 'mutans streptococcus', 'PCR', 'caries activity'], 'conditions': ['Dental Caries']}, 'descriptionModule': {'briefSummary': '90 saliva samples will be isolated from patient who possess different ages and caries activity, attending outpatient clinic of October University of Modern Sciences and Arts. Then the determination of the best selective media for mutans streptococcus isolated from saliva and authenticate the MS via PCR technique.'}, 'eligibilityModule': {'sex': 'ALL', 'stdAges': ['CHILD', 'ADULT'], 'maximumAge': '25 Years', 'minimumAge': '3 Years', 'samplingMethod': 'PROBABILITY_SAMPLE', 'studyPopulation': 'patients attending out patient clinic of October University for Modern Sciences and Arts.', 'healthyVolunteers': True, 'eligibilityCriteria': 'Inclusion Criteria:\n\n* healthy participant\n\nExclusion Criteria:\n\n* participant received antimicrobial therapy in previous month.\n* participant who taking xylitol chewing gum or undergo fluoride therapy.'}, 'identificationModule': {'nctId': 'NCT03802669', 'briefTitle': 'Molecular Assessment of Oral Mutans Streptococcus Isolated From Different Patients', 'organization': {'class': 'OTHER', 'fullName': 'October University for Modern Sciences and Arts'}, 'officialTitle': 'Molecular Assessment of Oral Mutans Streptococcus Isolated From Patients With Different Age and Caries Activity Via Selective Media and Protein Pattern.', 'orgStudyIdInfo': {'id': 'ETH10'}}, 'armsInterventionsModule': {'armGroups': [{'label': 'caries free children aged between 3-6', 'interventionNames': ['Other: oral mutans streptococcus']}, {'label': 'caries active children aged between 3-6', 'interventionNames': ['Other: oral mutans streptococcus']}, {'label': 'caries free children aged between 6-12', 'interventionNames': ['Other: oral mutans streptococcus']}, {'label': 'caries active children aged between 6-12', 'interventionNames': ['Other: oral mutans streptococcus']}, {'label': 'caries free adult aged between 18-25', 'interventionNames': ['Other: oral mutans streptococcus']}, {'label': 'caries active adult aged between 18-25', 'interventionNames': ['Other: oral mutans streptococcus']}], 'interventions': [{'name': 'oral mutans streptococcus', 'type': 'OTHER', 'description': 'quantitative assessment of mutans streptococcus of each group by using PCR and protein pattern', 'armGroupLabels': ['caries active adult aged between 18-25', 'caries active children aged between 3-6', 'caries active children aged between 6-12', 'caries free adult aged between 18-25', 'caries free children aged between 3-6', 'caries free children aged between 6-12']}]}, 'contactsLocationsModule': {'locations': [{'city': 'Cairo', 'country': 'Egypt', 'facility': 'October University of Modern Sciences and Arts', 'geoPoint': {'lat': 30.06263, 'lon': 31.24967}}], 'overallOfficials': [{'name': 'Naglaa Ezzeldin, lecturer', 'role': 'PRINCIPAL_INVESTIGATOR', 'affiliation': 'October University for Modern Sciences and Arts'}]}, 'ipdSharingStatementModule': {'ipdSharing': 'NO'}, 'sponsorCollaboratorsModule': {'leadSponsor': {'name': 'October University for Modern Sciences and Arts', 'class': 'OTHER'}, 'responsibleParty': {'type': 'PRINCIPAL_INVESTIGATOR', 'investigatorTitle': 'Lecturer of pediatric dentistry department, faculty of dentistry', 'investigatorFullName': 'Naglaa Ibrahim Ezz', 'investigatorAffiliation': 'October University for Modern Sciences and Arts'}}}}