Ignite Creation Date:
2025-12-24 @ 10:44 PM
Ignite Modification Date:
2025-12-25 @ 8:15 PM
Study NCT ID:
NCT03485235
Status:
COMPLETED
Last Update Posted:
2020-01-28
First Post:
2018-03-26
Is NOT Gene Therapy:
False
Has Adverse Events:
False
Brief Title:
Effect of Dilatation and Curettage on the Endometrial Receptivity
Sponsor:
Organization:
Raw JSON
{'hasResults': False, 'derivedSection': {'miscInfoModule': {'versionHolder': '2025-12-24'}, 'interventionBrowseModule': {'meshes': [{'id': 'D020554', 'term': 'Sperm Injections, Intracytoplasmic'}], 'ancestors': [{'id': 'D005307', 'term': 'Fertilization in Vitro'}, {'id': 'D027724', 'term': 'Reproductive Techniques, Assisted'}, {'id': 'D012099', 'term': 'Reproductive Techniques'}, {'id': 'D013812', 'term': 'Therapeutics'}, {'id': 'D008919', 'term': 'Investigative Techniques'}]}}, 'protocolSection': {'designModule': {'phases': ['NA'], 'studyType': 'INTERVENTIONAL', 'designInfo': {'allocation': 'RANDOMIZED', 'maskingInfo': {'masking': 'NONE'}, 'primaryPurpose': 'TREATMENT', 'interventionModel': 'PARALLEL'}, 'enrollmentInfo': {'type': 'ACTUAL', 'count': 160}}, 'statusModule': {'overallStatus': 'COMPLETED', 'startDateStruct': {'date': '2018-03-31', 'type': 'ACTUAL'}, 'expandedAccessInfo': {'hasExpandedAccess': False}, 'statusVerifiedDate': '2020-01', 'completionDateStruct': {'date': '2019-12-10', 'type': 'ACTUAL'}, 'lastUpdateSubmitDate': '2020-01-26', 'studyFirstSubmitDate': '2018-03-26', 'studyFirstSubmitQcDate': '2018-03-27', 'lastUpdatePostDateStruct': {'date': '2020-01-28', 'type': 'ACTUAL'}, 'studyFirstPostDateStruct': {'date': '2018-04-02', 'type': 'ACTUAL'}, 'primaryCompletionDateStruct': {'date': '2019-11-01', 'type': 'ACTUAL'}}, 'outcomesModule': {'primaryOutcomes': [{'measure': 'Live Birth Rate', 'timeFrame': '9 months'}]}, 'oversightModule': {'isFdaRegulatedDrug': False, 'isFdaRegulatedDevice': False}, 'conditionsModule': {'conditions': ['Embryo Implantation']}, 'descriptionModule': {'briefSummary': 'Effect of dilatation and curettage on the endometrial receptivity and pregnancy outcome in patients with recurrent implantation failure'}, 'eligibilityModule': {'sex': 'FEMALE', 'stdAges': ['ADULT'], 'maximumAge': '35 Years', 'minimumAge': '25 Years', 'healthyVolunteers': False, 'eligibilityCriteria': 'Inclusion Criteria:\n\n1. All the patients had at least 3 failed trials of IVF-ET with day 5 fresh blastocyst transferred\n2. At least 10 high-grade embryos were obtained in the previous trials\n3. Level of AMH more than or equal 1.1 ng/ml.\n4. Age: Less than or equal to 35 years\n\nExclusion Criteria:\n\n1. Patients with uterine pathology e.g. myoma , Asherman syndrome, Septum ,adenomyosis\n2. Hydrosalpinx\n3. Endometriosis\n4. patients with diagnosed autoimmune diseases affecting pregnancy e.g. S.L.E.'}, 'identificationModule': {'nctId': 'NCT03485235', 'briefTitle': 'Effect of Dilatation and Curettage on the Endometrial Receptivity', 'organization': {'class': 'OTHER', 'fullName': 'Ain Shams University'}, 'officialTitle': 'Effect of Dilatation and Curettage on the Endometrial Receptivity and Pregnancy Outcome in Patients With Recurrent Implantation Failure', 'orgStudyIdInfo': {'id': 'AS1764'}}, 'armsInterventionsModule': {'armGroups': [{'type': 'EXPERIMENTAL', 'label': 'D&C', 'interventionNames': ['Procedure: D&C', 'Procedure: ICSI']}, {'type': 'OTHER', 'label': 'No D&C', 'interventionNames': ['Procedure: ICSI']}], 'interventions': [{'name': 'D&C', 'type': 'PROCEDURE', 'description': 'Dilatation and curettage', 'armGroupLabels': ['D&C']}, {'name': 'ICSI', 'type': 'PROCEDURE', 'description': 'Intra Cytoplasmic Sperm Injection', 'armGroupLabels': ['D&C', 'No D&C']}]}, 'contactsLocationsModule': {'locations': [{'city': 'Cairo', 'country': 'Egypt', 'facility': 'Ain Shams University Maternity Hospital', 'geoPoint': {'lat': 30.06263, 'lon': 31.24967}}]}, 'sponsorCollaboratorsModule': {'leadSponsor': {'name': 'Ain Shams University', 'class': 'OTHER'}, 'responsibleParty': {'type': 'PRINCIPAL_INVESTIGATOR', 'investigatorTitle': 'Principal Investigator', 'investigatorFullName': 'Mohamed S Sweed, MD', 'investigatorAffiliation': 'Ain Shams University'}}}}