Ignite Creation Date:
2025-12-24 @ 1:29 PM
Ignite Modification Date:
2026-02-23 @ 8:08 PM
Study NCT ID:
NCT02523495
Status:
UNKNOWN
Last Update Posted:
2018-08-07
First Post:
2015-08-04
Is NOT Gene Therapy:
True
Has Adverse Events:
False
Brief Title:
The Clinical Outcome and the Exploration of Related Biomarkers of Target Therapy in Metastasis Colorectal Cancer
Sponsor:
Organization:
Raw JSON
{'hasResults': False, 'derivedSection': {'miscInfoModule': {'versionHolder': '2025-12-24'}, 'conditionBrowseModule': {'meshes': [{'id': 'D016609', 'term': 'Neoplasms, Second Primary'}], 'ancestors': [{'id': 'D009369', 'term': 'Neoplasms'}]}}, 'protocolSection': {'designModule': {'bioSpec': {'retention': 'SAMPLES_WITH_DNA', 'description': 'Whole blood'}, 'studyType': 'OBSERVATIONAL', 'designInfo': {'timePerspective': 'PROSPECTIVE', 'observationalModel': 'COHORT'}, 'enrollmentInfo': {'type': 'ESTIMATED', 'count': 120}, 'targetDuration': '5 Years', 'patientRegistry': True}, 'statusModule': {'overallStatus': 'UNKNOWN', 'lastKnownStatus': 'RECRUITING', 'startDateStruct': {'date': '2012-06'}, 'expandedAccessInfo': {'hasExpandedAccess': False}, 'statusVerifiedDate': '2018-08', 'completionDateStruct': {'date': '2022-07', 'type': 'ESTIMATED'}, 'lastUpdateSubmitDate': '2018-08-05', 'studyFirstSubmitDate': '2015-08-04', 'studyFirstSubmitQcDate': '2015-08-12', 'lastUpdatePostDateStruct': {'date': '2018-08-07', 'type': 'ACTUAL'}, 'studyFirstPostDateStruct': {'date': '2015-08-14', 'type': 'ESTIMATED'}, 'primaryCompletionDateStruct': {'date': '2020-07', 'type': 'ESTIMATED'}}, 'outcomesModule': {'primaryOutcomes': [{'measure': 'overall survival', 'timeFrame': '5 years'}]}, 'conditionsModule': {'keywords': ['Molecular Targeted Therapy', 'metastasis colorectal cancer', 'biomarker'], 'conditions': ['Neoplasms, Therapy-Associated']}, 'descriptionModule': {'briefSummary': 'Through clinical observation and data statistics, conclude the clinical outcome of target therapy in metastasis colorectal cancer and explore some biomarkers that relate to target therapy.', 'detailedDescription': '1. Establish a clinical database of patients who are diagnosed with metastasis colorectal cancer in tongji hospital.\n2. Build a biological specimen banks of metastasis colorectal cancer through collecting blood samples from those patients who have reached an agreement with us.\n3. Through clinical observation and data statistics, conclude the clinical outcome of target therapy in metastasis colorectal cancer.\n4. To extract DNA from the blood and explore some biomarkers that related to target therapy in metastasis colorectal cancer.'}, 'eligibilityModule': {'sex': 'ALL', 'stdAges': ['CHILD', 'ADULT', 'OLDER_ADULT'], 'samplingMethod': 'PROBABILITY_SAMPLE', 'studyPopulation': 'Metastasis colorectal cancer patients in Chinese Han population', 'healthyVolunteers': False, 'eligibilityCriteria': 'Inclusion Criteria:\n\n1. Metastasis colorectal cancer confirmed by histologically and radiography\n2. Receive target therapy over half a year\n3. Have a measurable lesions\n\nExclusion Criteria:\n\n1\\. A history of other malignant tumors in five years'}, 'identificationModule': {'nctId': 'NCT02523495', 'briefTitle': 'The Clinical Outcome and the Exploration of Related Biomarkers of Target Therapy in Metastasis Colorectal Cancer', 'organization': {'class': 'OTHER', 'fullName': 'Huazhong University of Science and Technology'}, 'orgStudyIdInfo': {'id': 'TJCC003-TTMCRC'}}, 'contactsLocationsModule': {'locations': [{'zip': '430000', 'city': 'Wuhan', 'state': 'Hubei', 'status': 'RECRUITING', 'country': 'China', 'contacts': [{'name': 'Yuan Xianglin, Professional', 'role': 'CONTACT'}], 'facility': 'Huazhong University of Science and Technology', 'geoPoint': {'lat': 30.58333, 'lon': 114.26667}}], 'centralContacts': [{'name': 'Yuan Xianglin, Professional', 'role': 'CONTACT', 'email': 'yxl@medmail.com.cn', 'phone': '13667241722'}, {'name': 'Zhao Ben, Master', 'role': 'CONTACT', 'email': 'zhaoben0609@163.com', 'phone': '15071206621'}]}, 'sponsorCollaboratorsModule': {'leadSponsor': {'name': 'Huazhong University of Science and Technology', 'class': 'OTHER'}, 'responsibleParty': {'type': 'PRINCIPAL_INVESTIGATOR', 'investigatorTitle': 'Professor, Chief physician', 'investigatorFullName': 'Xianglin Yuan', 'investigatorAffiliation': 'Huazhong University of Science and Technology'}}}}