Ignite Creation Date:
2025-12-24 @ 10:33 PM
Ignite Modification Date:
2025-12-28 @ 2:40 PM
Study NCT ID:
NCT04185935
Status:
RECRUITING
Last Update Posted:
2025-06-25
First Post:
2019-12-03
Is NOT Gene Therapy:
True
Has Adverse Events:
False
Brief Title:
Molecular Genetics Studies of Cancer Patients and Their Relatives
Sponsor:
Organization:
Raw JSON
{'hasResults': False, 'derivedSection': {'miscInfoModule': {'versionHolder': '2025-12-24'}, 'conditionBrowseModule': {'meshes': [{'id': 'D009369', 'term': 'Neoplasms'}]}}, 'protocolSection': {'designModule': {'bioSpec': {'retention': 'SAMPLES_WITH_DNA', 'description': 'Blood, saliva, eyebrow pluck, urine, tissue'}, 'studyType': 'OBSERVATIONAL', 'designInfo': {'timePerspective': 'PROSPECTIVE', 'observationalModel': 'FAMILY_BASED'}, 'enrollmentInfo': {'type': 'ESTIMATED', 'count': 999999}}, 'statusModule': {'overallStatus': 'RECRUITING', 'startDateStruct': {'date': '1997-04-18', 'type': 'ACTUAL'}, 'expandedAccessInfo': {'hasExpandedAccess': False}, 'statusVerifiedDate': '2025-06', 'completionDateStruct': {'date': '2033-08-18', 'type': 'ESTIMATED'}, 'lastUpdateSubmitDate': '2025-06-23', 'studyFirstSubmitDate': '2019-12-03', 'studyFirstSubmitQcDate': '2019-12-03', 'lastUpdatePostDateStruct': {'date': '2025-06-25', 'type': 'ACTUAL'}, 'studyFirstPostDateStruct': {'date': '2019-12-04', 'type': 'ACTUAL'}, 'primaryCompletionDateStruct': {'date': '2033-08-18', 'type': 'ESTIMATED'}}, 'outcomesModule': {'primaryOutcomes': [{'measure': 'Cancer risk assessment', 'timeFrame': 'Up to 10 years'}, {'measure': 'Exploratory biomarkers for future studies', 'timeFrame': 'Up to 10 years'}]}, 'oversightModule': {'oversightHasDmc': True, 'isFdaRegulatedDrug': False, 'isFdaRegulatedDevice': False}, 'conditionsModule': {'conditions': ['Malignant Neoplasm']}, 'descriptionModule': {'briefSummary': 'This trial studies the genetic and behavioral factors that may contribute to the development of specific cancers and how these factors may affect the outcome of the disease in patients with a history of cancer and their relatives.', 'detailedDescription': 'PRIMARY OBJECTIVES:\n\nI. To identify rare cancer patients and families in whom the pattern of disease suggests a genetic susceptibility to cancer or other etiology suggestive of a carcinogenic exposure and to characterize the underlying predisposition.\n\nII. To determine the contribution of heredity (genotype) and biomarkers to clinical outcome (phenotype, occurrence of new cancers, prognosis and quality of life) in subgroups of cancer patients with and without clinical high-risk features.\n\nOUTLINE:\n\nPatients may provide a sample of blood, a saliva sample, a sample of eyebrow plucks, a sample of urine, and/or stored tumor or healthy tissue.'}, 'eligibilityModule': {'sex': 'ALL', 'stdAges': ['CHILD', 'ADULT', 'OLDER_ADULT'], 'samplingMethod': 'PROBABILITY_SAMPLE', 'studyPopulation': 'Participants with a family history of cancer', 'healthyVolunteers': True, 'eligibilityCriteria': "Inclusion Criteria:\n\n* Individuals must have a personal history of cancer and/or a family history of cancer suggestive of the presence of an inherited predisposition. This inherited predisposition might manifest as:\n\n * Young age cancer diagnosis\n * Multiple primary neoplasms in affected member\n * The presence of rare tumor types in the family\n * Congenital malformations\n * Any other family clustering of cancer\n * Any other cancer-predisposing genetic diseases/conditions\n* Individuals may also be eligible by participation in the City of Hope Cancer Screening \\& Prevention Program Network (CSPPN) clinical service or on the basis of membership in a group known or suspected to have an increased risk of carrying a genetic alteration or of sustaining a particular exposure that would place that at increased risk of cancer. (Examples would include members of occupational cohorts like asbestos workers, individuals with multiple dysplastic nevi in the absence of a family history of cancer, and individuals descended from a particular tribe in the American Southwest who have an increased incidence of a rare genetic alteration associated with an increased risk of a specific cancer.)\n* Individuals and families may be referred to us in a number of different ways. After initial contact is made with a individual or family by family studies personnel; an individual within the bloodline will be identified as the historian. There may be more than one historian within a family\n* At least one historian must be wiling to provide information or access as needed to contact appropriate family members for documentation of cancer and for consent. An individual is considered to be eligible to participate if they criteria; contact with relatives is not always indicated\n* Individuals who are under 18 are eligible for study if they meet the criteria. Consent for participation must be given by a legal guardian or parent\n* Deceased patients may be included in the study. Public records, such as death certificates, can be used to confirm information from individuals or family members. If medical records are needed, consent for these records will be obtained from the deceased's next of kin. Next of kin refers to the following hierarchy of relatives; spouse, offspring, parents, and siblings. (Any further use of next of kin in this protocol should relate back to this hierarchy.) Archived tissue samples, such as pathology blocks or snap frozen tumor from a pathology department tumor bank (discard specimens) may be used for genetic research\n\nExclusion Criteria:\n\n* A family may be ineligible for study if the historian will not allow access to anyone within the family and thus, the accuracy of the family history cannot be established"}, 'identificationModule': {'nctId': 'NCT04185935', 'briefTitle': 'Molecular Genetics Studies of Cancer Patients and Their Relatives', 'organization': {'class': 'OTHER', 'fullName': 'City of Hope Medical Center'}, 'officialTitle': 'Molecular Genetics Studies of Cancer Patients and Their Relatives', 'orgStudyIdInfo': {'id': '96144'}, 'secondaryIdInfos': [{'id': 'NCI-2019-05695', 'type': 'REGISTRY', 'domain': 'CTRP (Clinical Trial Reporting Program)'}, {'id': '96144', 'type': 'OTHER', 'domain': 'City of Hope Comprehensive Cancer Center'}]}, 'armsInterventionsModule': {'armGroups': [{'label': 'Ancillary-correlative (biospecimen collection)', 'description': 'Participants may provide a sample of blood, a saliva sample, a sample of eyebrow plucks, a sample of urine, and/or stored tumor or healthy tissue.', 'interventionNames': ['Other: Biospecimen Collection', 'Other: Questionnaire Administration']}], 'interventions': [{'name': 'Biospecimen Collection', 'type': 'OTHER', 'description': 'Provide a sample of blood, a saliva sample, a sample of eyebrow plucks, a sample of urine, and/or stored tumor or healthy tissue', 'armGroupLabels': ['Ancillary-correlative (biospecimen collection)']}, {'name': 'Questionnaire Administration', 'type': 'OTHER', 'description': 'Ancillary studies', 'armGroupLabels': ['Ancillary-correlative (biospecimen collection)']}]}, 'contactsLocationsModule': {'locations': [{'zip': '85008', 'city': 'Phoenix', 'state': 'Arizona', 'status': 'RECRUITING', 'country': 'United States', 'contacts': [{'name': 'Ian K. Komenaka', 'role': 'CONTACT', 'email': 'Ian_Komenaka@dmgaz.org', 'phone': '602-344-5368'}, {'name': 'Ian K. Komenaka', 'role': 'PRINCIPAL_INVESTIGATOR'}], 'facility': 'Valleywise Comprehensive Health Center - Phoenix', 'geoPoint': {'lat': 33.44838, 'lon': -112.07404}}, {'zip': '94520', 'city': 'Concord', 'state': 'California', 'status': 'RECRUITING', 'country': 'United States', 'contacts': [{'name': 'Shellie Campos', 'role': 'CONTACT', 'email': 'shellie.campos@johnmuirhealth.com', 'phone': '925-947-3322'}, {'name': 'Shellie Campos', 'role': 'PRINCIPAL_INVESTIGATOR'}], 'facility': 'John Muir Medical Center-Concord Campus', 'geoPoint': {'lat': 37.97798, 'lon': -122.03107}}, {'zip': '91010', 'city': 'Duarte', 'state': 'California', 'status': 'RECRUITING', 'country': 'United States', 'contacts': [{'name': 'Jeffrey N. Weitzel', 'role': 'CONTACT', 'email': 'jweitzel@coh.org', 'phone': '626-218-4334'}, {'name': 'Jeffrey N. Weitzel', 'role': 'PRINCIPAL_INVESTIGATOR'}], 'facility': 'City of Hope Medical Center', 'geoPoint': {'lat': 34.13945, 'lon': -117.97729}}, {'zip': '92835', 'city': 'Fullerton', 'state': 'California', 'status': 'RECRUITING', 'country': 'United States', 'contacts': [{'name': 'William E. Lawler', 'role': 'CONTACT', 'email': 'William.Lawlor@StJoe.org', 'phone': '714-446-5801'}, {'name': 'William E. Lawler', 'role': 'PRINCIPAL_INVESTIGATOR'}], 'facility': 'Saint Jude Medical Center', 'geoPoint': {'lat': 33.87029, 'lon': -117.92534}}, {'zip': '92653', 'city': 'Laguna Hills', 'state': 'California', 'status': 'RECRUITING', 'country': 'United States', 'contacts': [{'name': 'Jeffrey N. Weitzel', 'role': 'CONTACT', 'email': 'jweitzel@coh.org', 'phone': '626-218-4334'}, {'name': 'Jeffrey N. Weitzel', 'role': 'PRINCIPAL_INVESTIGATOR'}], 'facility': 'Saddleback Memorial Medical Center', 'geoPoint': {'lat': 33.61252, 'lon': -117.71283}}, {'zip': '90033', 'city': 'Los Angeles', 'state': 'California', 'status': 'RECRUITING', 'country': 'United States', 'contacts': [{'name': 'Charite Ricker', 'role': 'CONTACT', 'email': 'Charite.Ricker@med.usc.edu', 'phone': '323-409-7710'}, {'name': 'Charite Ricker', 'role': 'PRINCIPAL_INVESTIGATOR'}], 'facility': 'USC / Norris Comprehensive Cancer Center', 'geoPoint': {'lat': 34.05223, 'lon': -118.24368}}, {'zip': '92868', 'city': 'Orange', 'state': 'California', 'status': 'RECRUITING', 'country': 'United States', 'contacts': [{'name': 'Jeffrey N. Weitzel', 'role': 'CONTACT', 'email': 'jweitzel@coh.org', 'phone': '626-218-4334'}, {'name': 'Jeffrey N. Weitzel', 'role': 'PRINCIPAL_INVESTIGATOR'}], 'facility': 'Saint Joseph Hospital - Orange', 'geoPoint': {'lat': 33.78779, 'lon': -117.85311}}, {'zip': '95661', 'city': 'Roseville', 'state': 'California', 'status': 'RECRUITING', 'country': 'United States', 'contacts': [{'name': 'Kristie A. Bobolis', 'role': 'CONTACT', 'email': 'bobolis@surewest.net', 'phone': '916-782-5106'}, {'name': 'Kristie A. Bobolis', 'role': 'PRINCIPAL_INVESTIGATOR'}], 'facility': 'Sutter Cancer Centers Radiation Oncology Services-Roseville', 'geoPoint': {'lat': 38.75212, 'lon': -121.28801}}, {'zip': '93105', 'city': 'Santa Barbara', 'state': 'California', 'status': 'RECRUITING', 'country': 'United States', 'contacts': [{'name': 'Frederic C. Kass', 'role': 'CONTACT', 'email': 'fkass@ccsb.org', 'phone': '805-563-5854'}, {'name': 'Frederic C. Kass', 'role': 'PRINCIPAL_INVESTIGATOR'}], 'facility': 'Cancer Center of Santa Barbara', 'geoPoint': {'lat': 34.42083, 'lon': -119.69819}}, {'zip': '33428', 'city': 'Boca Raton', 'state': 'Florida', 'status': 'RECRUITING', 'country': 'United States', 'contacts': [{'name': 'Louise E. Morrell', 'role': 'CONTACT', 'email': 'LMorrell@brrh.com', 'phone': '561-955-2141'}, {'name': 'Louise E. Morrell', 'role': 'PRINCIPAL_INVESTIGATOR'}], 'facility': 'Lynn Regional Cancer Center - West', 'geoPoint': {'lat': 26.35869, 'lon': -80.0831}}, {'zip': '33308', 'city': 'Fort Lauderdale', 'state': 'Florida', 'status': 'RECRUITING', 'country': 'United States', 'contacts': [{'name': 'Zdenka E. Segota', 'role': 'CONTACT', 'email': 'Ena.segota@holy-cross.com', 'phone': '954-267-7709'}, {'name': 'Zdenka E. Segota', 'role': 'PRINCIPAL_INVESTIGATOR'}], 'facility': 'Holy Cross Hospital', 'geoPoint': {'lat': 26.12231, 'lon': -80.14338}}, {'zip': '83854', 'city': 'Post Falls', 'state': 'Idaho', 'status': 'RECRUITING', 'country': 'United States', 'contacts': [{'name': 'Jeffrey W. Allen', 'role': 'CONTACT', 'email': 'Mhander@kh.org', 'phone': '208-625-4728'}, {'name': 'Jeffrey W. Allen', 'role': 'PRINCIPAL_INVESTIGATOR'}], 'facility': 'Kootenai Cancer Center', 'geoPoint': {'lat': 47.71796, 'lon': -116.95159}}, {'zip': '60612', 'city': 'Chicago', 'state': 'Illinois', 'status': 'RECRUITING', 'country': 'United States', 'contacts': [{'name': 'Pamela Ganschow', 'role': 'CONTACT', 'email': 'pganschow@cookcountyhhs.org', 'phone': '312-864-4436'}, {'name': 'Pamela Ganschow', 'role': 'PRINCIPAL_INVESTIGATOR'}], 'facility': 'John H Stroger Jr Hospital of Cook County', 'geoPoint': {'lat': 41.85003, 'lon': -87.65005}}, {'zip': '60612', 'city': 'Chicago', 'state': 'Illinois', 'status': 'RECRUITING', 'country': 'United States', 'contacts': [{'name': 'Lydia Usha', 'role': 'CONTACT', 'email': 'Lydia_Usha@rush.edu', 'phone': '312-563-2200'}, {'name': 'Lydia Usha', 'role': 'PRINCIPAL_INVESTIGATOR'}], 'facility': 'Rush University Medical Center', 'geoPoint': {'lat': 41.85003, 'lon': -87.65005}}, {'zip': '52403', 'city': 'Cedar Rapids', 'state': 'Iowa', 'status': 'RECRUITING', 'country': 'United States', 'contacts': [{'name': 'Amie Hass', 'role': 'CONTACT', 'email': 'ahass@mercycare.org', 'phone': '319-398-6732'}, {'name': 'Amie Hass', 'role': 'PRINCIPAL_INVESTIGATOR'}], 'facility': 'Mercy Hospital', 'geoPoint': {'lat': 42.00833, 'lon': -91.64407}}, {'zip': '20814', 'city': 'Bethesda', 'state': 'Maryland', 'status': 'RECRUITING', 'country': 'United States', 'contacts': [{'name': 'Carolyn B. Hendricks', 'role': 'CONTACT', 'email': 'carolyn.hendricks53@verizon.net', 'phone': '301-897-1503'}, {'name': 'Carolyn B. Hendricks', 'role': 'PRINCIPAL_INVESTIGATOR'}], 'facility': 'Suburban Hospital', 'geoPoint': {'lat': 38.98067, 'lon': -77.10026}}, {'zip': '21702', 'city': 'Frederick', 'state': 'Maryland', 'status': 'RECRUITING', 'country': 'United States', 'contacts': [{'name': 'Patricia A. Rice', 'role': 'CONTACT', 'email': 'price@fmh.org', 'phone': '301-418-5010'}, {'name': 'Patricia A. Rice', 'role': 'PRINCIPAL_INVESTIGATOR'}], 'facility': 'Frederick Oncology Hematology Associates', 'geoPoint': {'lat': 39.41427, 'lon': -77.41054}}, {'zip': '02135', 'city': 'Brighton', 'state': 'Massachusetts', 'status': 'RECRUITING', 'country': 'United States', 'contacts': [{'name': 'Beth B. Herrick', 'role': 'CONTACT', 'email': 'Beth.Herrick@steward.org', 'phone': '617-789-3232'}, {'name': 'Beth B. Herrick', 'role': 'PRINCIPAL_INVESTIGATOR'}], 'facility': "Steward Saint Elizabeth's Medical Center", 'geoPoint': {'lat': 42.3501, 'lon': -71.15644}}, {'zip': '08822', 'city': 'Flemington', 'state': 'New Jersey', 'status': 'RECRUITING', 'country': 'United States', 'contacts': [{'name': 'Kenneth B. Blankstein', 'role': 'CONTACT', 'email': 'kblankstein@hhpnj.org', 'phone': '908-788-2566'}, {'name': 'Kenneth B. Blankstein', 'role': 'PRINCIPAL_INVESTIGATOR'}], 'facility': 'Hunterdon Medical Center', 'geoPoint': {'lat': 40.51233, 'lon': -74.85933}}, {'zip': '87102', 'city': 'Albuquerque', 'state': 'New Mexico', 'status': 'RECRUITING', 'country': 'United States', 'contacts': [{'name': 'Malcolm H. Purdy', 'role': 'CONTACT', 'email': 'malcolm.purdy@ardenthealth.com', 'phone': '505-727-3040'}, {'name': 'Malcolm H. Purdy', 'role': 'PRINCIPAL_INVESTIGATOR'}], 'facility': 'Lovelace Medical Center-Downtown', 'geoPoint': {'lat': 35.08449, 'lon': -106.65114}}, {'zip': '87109', 'city': 'Albuquerque', 'state': 'New Mexico', 'status': 'RECRUITING', 'country': 'United States', 'contacts': [{'name': 'Annette C. Fontaine', 'role': 'CONTACT', 'email': 'afontaine@nmohc.com', 'phone': '505-480-1462'}, {'name': 'Annette C. Fontaine', 'role': 'PRINCIPAL_INVESTIGATOR'}], 'facility': 'New Mexico Oncology Hematology Consultants', 'geoPoint': {'lat': 35.08449, 'lon': -106.65114}}, {'zip': '87110', 'city': 'Albuquerque', 'state': 'New Mexico', 'status': 'RECRUITING', 'country': 'United States', 'contacts': [{'name': 'Kenneth J. Smith', 'role': 'CONTACT', 'phone': '505-559-6143'}, {'name': 'Kenneth J. Smith', 'role': 'PRINCIPAL_INVESTIGATOR'}], 'facility': 'Presbyterian Kaseman Hospital', 'geoPoint': {'lat': 35.08449, 'lon': -106.65114}}, {'zip': '10549-3417', 'city': 'Mount Kisco', 'state': 'New York', 'status': 'RECRUITING', 'country': 'United States', 'contacts': [{'name': 'Nancy Cohen', 'role': 'CONTACT', 'email': 'NCohen@nwhc.net', 'phone': '914-242-7649'}, {'name': 'Nancy Cohen', 'role': 'PRINCIPAL_INVESTIGATOR'}], 'facility': 'Mount Kisco Medical Group at Northern Westchester Hospital', 'geoPoint': {'lat': 41.20426, 'lon': -73.72708}}, {'zip': '12601', 'city': 'Poughkeepsie', 'state': 'New York', 'status': 'RECRUITING', 'country': 'United States', 'contacts': [{'name': 'Jonathan Clyman', 'role': 'CONTACT', 'email': 'jclyman@Health-quest.org', 'phone': '845-483-6279'}, {'name': 'Jonathan Clyman', 'role': 'PRINCIPAL_INVESTIGATOR'}], 'facility': 'Health Quest Medical Practice PC-Cardio Thoracic', 'geoPoint': {'lat': 41.70037, 'lon': -73.92097}}, {'zip': '44710', 'city': 'Canton', 'state': 'Ohio', 'status': 'RECRUITING', 'country': 'United States', 'contacts': [{'name': 'Shruti Trehan', 'role': 'CONTACT', 'email': 'Shruti.trehan@aultman.com', 'phone': '330-363-2286'}, {'name': 'Shruti Trehan', 'role': 'PRINCIPAL_INVESTIGATOR'}], 'facility': 'Aultman Health Foundation', 'geoPoint': {'lat': 40.79895, 'lon': -81.37845}}, {'zip': '97701', 'city': 'Bend', 'state': 'Oregon', 'status': 'RECRUITING', 'country': 'United States', 'contacts': [{'name': 'Coralia B. Calomeni', 'role': 'CONTACT', 'email': 'cbcalomeni@stcharleshealthcare.org', 'phone': '541-706-5800'}, {'name': 'Coralia B. Calomeni', 'role': 'PRINCIPAL_INVESTIGATOR'}], 'facility': 'Saint Charles Health System', 'geoPoint': {'lat': 44.05817, 'lon': -121.31531}}, {'zip': '19301', 'city': 'Paoli', 'state': 'Pennsylvania', 'status': 'RECRUITING', 'country': 'United States', 'contacts': [{'name': 'Michael B. Dabrow', 'role': 'CONTACT', 'email': 'DabrowM@MLHS.ORG'}, {'name': 'Michael B. Dabrow', 'role': 'PRINCIPAL_INVESTIGATOR'}], 'facility': 'Paoli Memorial Hospital', 'geoPoint': {'lat': 40.04205, 'lon': -75.47631}}, {'zip': '19611', 'city': 'West Reading', 'state': 'Pennsylvania', 'status': 'RECRUITING', 'country': 'United States', 'contacts': [{'name': 'Terrence P. Cescon', 'role': 'CONTACT', 'email': 'CesconT@readinghospital.org', 'phone': '484-628-8000'}, {'name': 'Terrence P. Cescon', 'role': 'PRINCIPAL_INVESTIGATOR'}], 'facility': 'Reading Hospital', 'geoPoint': {'lat': 40.3337, 'lon': -75.94743}}, {'zip': '79106', 'city': 'Amarillo', 'state': 'Texas', 'status': 'RECRUITING', 'country': 'United States', 'contacts': [{'name': 'Anita Ravipati', 'role': 'CONTACT', 'email': 'aravipati@harringtoncc.org'}, {'name': 'Anita Ravipati', 'role': 'PRINCIPAL_INVESTIGATOR'}], 'facility': 'The Don and Sybil Harrington Cancer Center', 'geoPoint': {'lat': 35.222, 'lon': -101.8313}}, {'zip': '77030', 'city': 'Houston', 'state': 'Texas', 'status': 'NOT_YET_RECRUITING', 'country': 'United States', 'contacts': [{'name': 'April D. Sorrell', 'role': 'CONTACT', 'phone': '713-798-6970'}, {'name': 'April D. Sorrell', 'role': 'PRINCIPAL_INVESTIGATOR'}], 'facility': 'Baylor College of Medicine/Dan L Duncan Comprehensive Cancer Center', 'geoPoint': {'lat': 29.76328, 'lon': -95.36327}}, {'zip': '78041', 'city': 'Laredo', 'state': 'Texas', 'status': 'RECRUITING', 'country': 'United States', 'contacts': [{'name': 'Gary W. Unzeitig', 'role': 'CONTACT', 'email': 'drgwu@laredobreastcare.com', 'phone': '956-726-3691'}, {'name': 'Gary W. Unzeitig', 'role': 'PRINCIPAL_INVESTIGATOR'}], 'facility': "Doctor's Hospital of Laredo", 'geoPoint': {'lat': 27.50641, 'lon': -99.50754}}, {'zip': '79410', 'city': 'Lubbock', 'state': 'Texas', 'status': 'RECRUITING', 'country': 'United States', 'contacts': [{'name': 'Isaac Tafur', 'role': 'CONTACT', 'email': 'oncmd98@yahoo.com', 'phone': '806-725-7993'}, {'name': 'Isaac Tafur', 'role': 'PRINCIPAL_INVESTIGATOR'}], 'facility': 'Covenant Medical Center', 'geoPoint': {'lat': 33.57786, 'lon': -101.85517}}, {'zip': '54935', 'city': 'Fond du Lac', 'state': 'Wisconsin', 'status': 'RECRUITING', 'country': 'United States', 'contacts': [{'name': 'Michael W. Jones', 'role': 'CONTACT', 'phone': '920-926-4100'}, {'name': 'Michael W. Jones', 'role': 'PRINCIPAL_INVESTIGATOR'}], 'facility': 'Saint Agnes Hospital/Agnesian Cancer Center', 'geoPoint': {'lat': 43.775, 'lon': -88.43883}}, {'zip': '53188', 'city': 'Waukesha', 'state': 'Wisconsin', 'status': 'RECRUITING', 'country': 'United States', 'contacts': [{'name': 'Christopher R. Hake', 'role': 'CONTACT', 'email': 'chakemd@gmail.com', 'phone': '262-928-5539'}, {'name': 'Christopher R. Hake', 'role': 'PRINCIPAL_INVESTIGATOR'}], 'facility': 'ProHealth Waukesha Memorial Hospital', 'geoPoint': {'lat': 43.01168, 'lon': -88.23148}}, {'zip': '82001', 'city': 'Cheyenne', 'state': 'Wyoming', 'status': 'RECRUITING', 'country': 'United States', 'contacts': [{'name': 'Jennifer Van Horn', 'role': 'CONTACT', 'email': 'Jennifer.VanHorn@crmcwy.org', 'phone': '307-996-1517'}, {'name': 'Jennifer Van Horn', 'role': 'PRINCIPAL_INVESTIGATOR'}], 'facility': 'Cheyenne Regional Medical Center-West', 'geoPoint': {'lat': 41.13998, 'lon': -104.82025}}, {'city': 'Bogotá', 'state': 'Cundinamarca', 'status': 'RECRUITING', 'country': 'Colombia', 'contacts': [{'name': 'Sandra X. Franco', 'role': 'CONTACT', 'email': 'sfranco@clinicadelcountry.com', 'phone': '011 57 1 5300470'}, {'name': 'Sandra X. Franco', 'role': 'PRINCIPAL_INVESTIGATOR'}], 'facility': 'Clinica del Country'}, {'city': 'Medellín', 'status': 'RECRUITING', 'country': 'Colombia', 'contacts': [{'name': 'Alicia M. Cock-Rada', 'role': 'CONTACT', 'email': 'alicia@oncogenetica.co', 'phone': '574 3409393'}, {'name': 'Alicia M. Cock-Rada', 'role': 'PRINCIPAL_INVESTIGATOR'}], 'facility': 'Instituto de Cancerologia Las Americas', 'geoPoint': {'lat': 6.245, 'lon': -75.57151}}, {'zip': 'CP 44340', 'city': 'Guadalajara', 'state': 'Jalisco', 'status': 'RECRUITING', 'country': 'Mexico', 'contacts': [{'name': 'Adrian Daneri-Navarro', 'role': 'CONTACT', 'email': 'Daneri@cucs.udg.mx', 'phone': '33 10585261', 'phoneExt': '33871'}, {'name': 'Adrian Daneri-Navarro', 'role': 'PRINCIPAL_INVESTIGATOR'}], 'facility': 'University of Guadalajara', 'geoPoint': {'lat': 20.67738, 'lon': -103.34749}}, {'zip': '14080', 'city': 'Mexico City', 'state': 'Tlalpan', 'status': 'RECRUITING', 'country': 'Mexico', 'contacts': [{'name': 'Yanin Chavarri', 'role': 'CONTACT', 'email': 'yanin.chavarrig@incmnsz.mx', 'phone': '525554870900', 'phoneExt': '2254'}, {'name': 'Yanin Chavarri', 'role': 'PRINCIPAL_INVESTIGATOR'}], 'facility': 'Salvador Zubiran National Institute of Health Sciences and Nutrition', 'geoPoint': {'lat': 19.42847, 'lon': -99.12766}}, {'city': 'Nuevo León', 'status': 'RECRUITING', 'country': 'Mexico', 'contacts': [{'name': 'Cynthia Villarreal-Garza', 'role': 'CONTACT', 'email': 'cynthiavg@gmail.com', 'phone': '528183898395'}, {'name': 'Cynthia Villarreal-Garza', 'role': 'PRINCIPAL_INVESTIGATOR'}], 'facility': 'Monterrey Institute of Technology-TecSalud', 'geoPoint': {'lat': 32.4095, 'lon': -115.18896}}, {'zip': 'Lima 34', 'city': 'Lima', 'status': 'RECRUITING', 'country': 'Peru', 'contacts': [{'name': 'Julio E. Abugattas Saba', 'role': 'CONTACT', 'email': 'jabugattas@inen.sld.pe', 'phone': '51993579810'}, {'name': 'Julio E. Abugattas Saba', 'role': 'PRINCIPAL_INVESTIGATOR'}], 'facility': 'Instituto Nacional de Enfermedades Neoplasicas', 'geoPoint': {'lat': -12.04318, 'lon': -77.02824}}, {'zip': '00936', 'city': 'San Juan', 'status': 'RECRUITING', 'country': 'Puerto Rico', 'contacts': [{'name': 'Marcia R. Cruz-Correa', 'role': 'CONTACT', 'email': 'marcia.cruz1@upr.edu', 'phone': '787-772-8300'}, {'name': 'Marcia R. Cruz-Correa', 'role': 'PRINCIPAL_INVESTIGATOR'}], 'facility': 'University of Puerto Rico', 'geoPoint': {'lat': 18.46633, 'lon': -66.10572}}], 'centralContacts': [{'name': 'Stephen Gruber', 'role': 'CONTACT', 'email': 'sgruber@coh.org'}], 'overallOfficials': [{'name': 'Stephen Gruber, MD', 'role': 'PRINCIPAL_INVESTIGATOR', 'affiliation': 'City of Hope Medical Center'}]}, 'sponsorCollaboratorsModule': {'leadSponsor': {'name': 'City of Hope Medical Center', 'class': 'OTHER'}, 'collaborators': [{'name': 'National Cancer Institute (NCI)', 'class': 'NIH'}], 'responsibleParty': {'type': 'SPONSOR'}}}}