Ignite Creation Date:
2025-12-24 @ 10:10 PM
Ignite Modification Date:
2025-12-25 @ 7:45 PM
Study NCT ID:
NCT01273935
Status:
COMPLETED
Last Update Posted:
2011-01-11
First Post:
2011-01-10
Is NOT Gene Therapy:
False
Has Adverse Events:
False
Brief Title:
Dose-Dependent Effect of Early Antiplatelet Therapy in Acute Ischemic Stroke
Sponsor:
Organization:
Raw JSON
{'hasResults': False, 'derivedSection': {'miscInfoModule': {'versionHolder': '2025-12-24'}}, 'protocolSection': {'designModule': {'studyType': 'OBSERVATIONAL', 'designInfo': {'timePerspective': 'RETROSPECTIVE', 'observationalModel': 'CASE_ONLY'}, 'enrollmentInfo': {'type': 'ACTUAL', 'count': 400}}, 'statusModule': {'overallStatus': 'COMPLETED', 'startDateStruct': {'date': '2010-01'}, 'expandedAccessInfo': {'hasExpandedAccess': False}, 'statusVerifiedDate': '2010-01', 'completionDateStruct': {'date': '2010-12', 'type': 'ACTUAL'}, 'lastUpdateSubmitDate': '2011-01-10', 'studyFirstSubmitDate': '2011-01-10', 'studyFirstSubmitQcDate': '2011-01-10', 'lastUpdatePostDateStruct': {'date': '2011-01-11', 'type': 'ESTIMATED'}, 'studyFirstPostDateStruct': {'date': '2011-01-11', 'type': 'ESTIMATED'}}, 'outcomesModule': {'primaryOutcomes': [{'measure': 'Result of platelet function test', 'description': 'Aggregometry result of antiplatelet therapy'}]}, 'oversightModule': {'oversightHasDmc': False}, 'conditionsModule': {'keywords': ['Aspirin, Acute Cerebrovascular Ischemia, Platelet Function'], 'conditions': ['Test the Efficacy of Antiplatelet Regimes in Acute Stroke']}, 'descriptionModule': {'briefSummary': 'The aim of this study is to evaluate the low-response prevalence of early antiplatelet therapy and to test the influence of different aspirin dosages in patients with acute ischemic strokes (AIS).', 'detailedDescription': 'Antiplatelet agents are important therapeutic options in treating patients with acute ischemic strokes to prevent recurrent ischemic events or death. The aim of this study was to evaluate the low-response prevalence of early antiplatelet therapy and the influence of different aspirin dosages in patients with acute ischemic strokes (AIS).'}, 'eligibilityModule': {'sex': 'ALL', 'stdAges': ['ADULT', 'OLDER_ADULT'], 'minimumAge': '18 Years', 'samplingMethod': 'NON_PROBABILITY_SAMPLE', 'studyPopulation': 'Patients admitted to the stroke unit', 'healthyVolunteers': False, 'eligibilityCriteria': 'Inclusion Criteria:\n\n* suspected acute cerebrovascular ischemic events and patients who were admitted to the stroke unit where antiplatelet therapy was initiated\n\nExclusion Criteria:\n\n* severe liver disorders, current gastrointestinal disorders, congestive heart failure, life-threatening malignancies and a personal or family history of bleeding disorders'}, 'identificationModule': {'nctId': 'NCT01273935', 'briefTitle': 'Dose-Dependent Effect of Early Antiplatelet Therapy in Acute Ischemic Stroke', 'organization': {'class': 'OTHER', 'fullName': 'Ruhr University of Bochum'}, 'officialTitle': 'Dose-Dependent Effect of Early Antiplatelet Therapy in Acute Ischemic Stroke', 'orgStudyIdInfo': {'id': 'MevesASS01'}}, 'armsInterventionsModule': {'armGroups': [{'label': 'Responder', 'description': 'Responder versus Non-Responder as a result of platelet function test'}, {'label': 'Non-Responder', 'description': 'According to the result of platelet function test'}]}, 'contactsLocationsModule': {'locations': [{'zip': 'D-44791', 'city': 'Bochum', 'state': 'North Rhine-Westphalia', 'country': 'Germany', 'facility': 'Department of Neurology, St. Josef - Hospital, Ruhr-University', 'geoPoint': {'lat': 51.48165, 'lon': 7.21648}}], 'overallOfficials': [{'name': 'Saskia H Meves, MD', 'role': 'PRINCIPAL_INVESTIGATOR', 'affiliation': 'Department of Neurology, St. Josef - Hospital, Bochum, Germany'}]}, 'sponsorCollaboratorsModule': {'leadSponsor': {'name': 'Ruhr University of Bochum', 'class': 'OTHER'}, 'responsibleParty': {'oldNameTitle': 'Medical Faculty Ruhr-University Bochum', 'oldOrganization': 'Dekanat der Medizinischen Fakultät, Forschungsreferat - FoRUM'}}}}