Ignite Creation Date:
2025-12-24 @ 9:56 PM
Ignite Modification Date:
2025-12-30 @ 10:16 PM
Study NCT ID:
NCT01319032
Status:
UNKNOWN
Last Update Posted:
2011-03-21
First Post:
2011-03-17
Is NOT Gene Therapy:
True
Has Adverse Events:
False
Brief Title:
Genetic Polymorphism and Israeli Top-level Swimmers' Performance and Expertise
Sponsor:
Organization:
Raw JSON
{'hasResults': False, 'derivedSection': {'miscInfoModule': {'versionHolder': '2025-12-24'}}, 'protocolSection': {'designModule': {'bioSpec': {'retention': 'SAMPLES_WITH_DNA', 'description': 'Whole blood'}, 'studyType': 'OBSERVATIONAL', 'designInfo': {'timePerspective': 'PROSPECTIVE', 'observationalModel': 'COHORT'}, 'enrollmentInfo': {'type': 'ESTIMATED', 'count': 200}}, 'statusModule': {'overallStatus': 'UNKNOWN', 'lastKnownStatus': 'NOT_YET_RECRUITING', 'startDateStruct': {'date': '2011-04'}, 'expandedAccessInfo': {'hasExpandedAccess': False}, 'statusVerifiedDate': '2011-03', 'completionDateStruct': {'date': '2012-12', 'type': 'ESTIMATED'}, 'lastUpdateSubmitDate': '2011-03-17', 'studyFirstSubmitDate': '2011-03-17', 'studyFirstSubmitQcDate': '2011-03-17', 'lastUpdatePostDateStruct': {'date': '2011-03-21', 'type': 'ESTIMATED'}, 'studyFirstPostDateStruct': {'date': '2011-03-21', 'type': 'ESTIMATED'}, 'primaryCompletionDateStruct': {'date': '2011-12', 'type': 'ESTIMATED'}}, 'outcomesModule': {'primaryOutcomes': [{'measure': 'Identification of genes associated with swimming performance', 'timeFrame': 'One year'}]}, 'oversightModule': {'oversightHasDmc': True}, 'conditionsModule': {'conditions': ['Genetic Polymorphism Connected to Top-level Swimmers']}, 'referencesModule': {'references': [{'pmid': '26284168', 'type': 'DERIVED', 'citation': 'Ben-Zaken S, Eliakim A, Nemet D, Rabinovich M, Kassem E, Meckel Y. ACTN3 Polymorphism: Comparison Between Elite Swimmers and Runners. Sports Med Open. 2015;1(1):13. doi: 10.1186/s40798-015-0023-y. Epub 2015 Jun 14.'}]}, 'descriptionModule': {'briefSummary': 'In a study conducted in our laboratory few years ago, we genotyped 22 genes in 2 athletic groups (endurance and sprinters) and in age and gender matched nonathletic controls. Few of these genes were found to be associated with athletic performance and area of specificity. Since then a few more genes have been found that are related to athletic performance, and we intend to study various genes related to 3 genetic cascade: genes associated with body fluid balance and homeostasis, genes associated with muscle strength, and genes associated with bioenergy. The results of this study compared with athletic level will provide deeper insight into the genetic mechanisms involved in performance.'}, 'eligibilityModule': {'sex': 'ALL', 'stdAges': ['CHILD', 'ADULT'], 'maximumAge': '40 Years', 'minimumAge': '13 Years', 'samplingMethod': 'PROBABILITY_SAMPLE', 'studyPopulation': 'Swimmers training at the Wingate Institute', 'healthyVolunteers': True, 'eligibilityCriteria': 'Inclusion Criteria:\n\n* Top-level swimmers\n* Other swimmers\n\nExclusion Criteria:\n\n* All others'}, 'identificationModule': {'nctId': 'NCT01319032', 'briefTitle': "Genetic Polymorphism and Israeli Top-level Swimmers' Performance and Expertise", 'organization': {'class': 'OTHER_GOV', 'fullName': 'Hillel Yaffe Medical Center'}, 'orgStudyIdInfo': {'id': '0013-11-HYMC'}}, 'armsInterventionsModule': {'armGroups': [{'label': 'I. Top-level swimmers', 'interventionNames': ['Other: Extraction of whole blood']}, {'label': 'II. Control', 'description': 'Other swimmers', 'interventionNames': ['Other: Extraction of whole blood']}], 'interventions': [{'name': 'Extraction of whole blood', 'type': 'OTHER', 'description': 'Extraction of DNA from whole blood', 'armGroupLabels': ['I. Top-level swimmers', 'II. Control']}]}, 'contactsLocationsModule': {'locations': [{'city': 'Netanya', 'country': 'Israel', 'contacts': [{'name': 'Sigal Ben Zaken, PhD', 'role': 'PRINCIPAL_INVESTIGATOR'}], 'facility': 'Wingate Institute', 'geoPoint': {'lat': 32.33291, 'lon': 34.85992}}], 'centralContacts': [{'name': 'Sigal Ben Zaken, PhD', 'role': 'CONTACT', 'phone': '972-52-2209853'}]}, 'sponsorCollaboratorsModule': {'leadSponsor': {'name': 'Hillel Yaffe Medical Center', 'class': 'OTHER_GOV'}, 'collaborators': [{'name': 'Wingate Institute', 'class': 'OTHER'}], 'responsibleParty': {'oldNameTitle': 'Eias Kassem, MD', 'oldOrganization': 'Hillel Yaffe Medical Center'}}}}