Ignite Creation Date:
2025-12-24 @ 9:48 PM
Ignite Modification Date:
2025-12-30 @ 1:45 AM
Study NCT ID:
NCT01055132
Status:
COMPLETED
Last Update Posted:
2018-06-19
First Post:
2010-01-22
Is NOT Gene Therapy:
True
Has Adverse Events:
True
Brief Title:
Dispensing Evaluation of New Daily Disposable Toric Soft Contact Lens.
Sponsor:
Organization:
Raw JSON
{'hasResults': True, 'derivedSection': {'miscInfoModule': {'versionHolder': '2025-12-24'}, 'conditionBrowseModule': {'meshes': [{'id': 'D001251', 'term': 'Astigmatism'}], 'ancestors': [{'id': 'D012030', 'term': 'Refractive Errors'}, {'id': 'D005128', 'term': 'Eye Diseases'}]}}, 'resultsSection': {'moreInfoModule': {'pointOfContact': {'email': 'RFrankl1@its.jnj.com', 'phone': '1-904-443-1379', 'title': 'Ross Franklin', 'organization': 'Johnson & Johnson Vision Care'}, 'certainAgreement': {'otherDetails': 'Publications require agreement and written approval from Sponsor.', 'restrictionType': 'OTHER', 'piSponsorEmployee': False, 'restrictiveAgreement': True}}, 'adverseEventsModule': {'eventGroups': [{'id': 'EG000', 'title': 'Etafilcon A Toric / Nelfilcon A Toric', 'description': 'etafilcon A toric contact lens worn daily during first period of a maximum of 9 days, nelfilcon A toric contact lens worn during second period of a maximum of 9 days', 'otherNumAtRisk': 69, 'otherNumAffected': 0, 'seriousNumAtRisk': 69, 'seriousNumAffected': 0}], 'frequencyThreshold': '5'}, 'outcomeMeasuresModule': {'outcomeMeasures': [{'type': 'PRIMARY', 'title': 'Monocular Visual Acuity on LogMAR Scale', 'denoms': [{'units': 'Participants', 'counts': [{'value': '67', 'groupId': 'OG000'}, {'value': '67', 'groupId': 'OG001'}]}], 'groups': [{'id': 'OG000', 'title': 'Etafilcon A Toric (Test Lens)', 'description': 'Etafilcon A toric is a daily disposable hydrogel toric lens with the addition of a wetting agent, developed for a wider ranged of prescriptions; worn for 5-9 days'}, {'id': 'OG001', 'title': 'Nelfilcon A Toric (Active Comparator)', 'description': 'An existing, daily disposable toric contact lens; worn 5-9 days'}], 'classes': [{'categories': [{'measurements': [{'value': '-0.065', 'spread': '0.0777', 'groupId': 'OG000'}, {'value': '-0.038', 'spread': '0.1057', 'groupId': 'OG001'}]}]}], 'analyses': [{'groupIds': ['OG000', 'OG001'], 'paramType': 'Least-square mean difference', 'ciNumSides': 'TWO_SIDED', 'ciPctValue': '95', 'paramValue': '-0.037', 'ciLowerLimit': '-0.041', 'ciUpperLimit': '-0.0013', 'dispersionType': 'STANDARD_ERROR_OF_MEAN', 'dispersionValue': '0.0072', 'estimateComment': 'Comparison between study lenses was carried out using 2-sided 95% confidence interval of the least-square mean difference(test minus control). The non-inferiority was concluded if the upper limit of the confidence limit is below 0.05 LogMAR.', 'groupDescription': 'Ho:The test lens is non-inferior to the active comparator lens for monocular visual performance on logMAR scale at 1-week follow-up. A non-inferiority margin of 0.05 logMAR was used.', 'statisticalMethod': 'linear mixed model', 'nonInferiorityType': 'NON_INFERIORITY_OR_EQUIVALENCE', 'statisticalComment': 'Sequence of wear, period and lens were included as fixed effects; site, patient, eye\\*patient, period\\*patient and period\\*eye\\*patient as random effects.', 'nonInferiorityComment': 'Based on historical data, a minimum of 42 subjects is needed to achieve 80% power with 0.05 type I error.'}], 'paramType': 'MEAN', 'timeFrame': 'After 5 to 9 days of lens wear', 'description': "Distance (4 meter) high contrast standard resolution (ETDRS) acuity was measured twice for each eye. Visual acuity describes the acuteness or sharpness of vision; the ability to perceive small details. Visual acuity is a measure of spacial resolution of the visual processing system; it's tested by requiring the person being tested to identify characters (like letters and numbers)on a chart from a set distance. LogMAR charts are used to assess visual acuity for research studies. LogMAR means Minimum Angle of Resolution. This has lead to the assertion that research is done using a logarithmic progression in size of letters on a test chart gives the most accurate visual acuity measurement. The reason for this is, unlike other charts, LogMAR chart has equal gradation between the letters on the line and the space between the lines. And, there is a fixed number of letters per line.", 'unitOfMeasure': 'logMAR', 'dispersionType': 'Standard Deviation', 'reportingStatus': 'POSTED', 'populationDescription': 'Analysis was conducted on subjects who successfully complete the study.'}, {'type': 'PRIMARY', 'title': 'Binocular Visual Acuity on LogMAR Scale', 'denoms': [{'units': 'Participants', 'counts': [{'value': '67', 'groupId': 'OG000'}, {'value': '67', 'groupId': 'OG001'}]}], 'groups': [{'id': 'OG000', 'title': 'Etafilcon A Toric (Test Lens)', 'description': 'Etafilcon A toric is a daily disposable hydrogel toric lens with the addition of a wetting agent, developed for a wider ranged of prescriptions; worn for 5-9 days'}, {'id': 'OG001', 'title': 'Nelfilcon A Toric Lens (Active Comparator)', 'description': 'An existing, daily disposable toric contact lens; worn 5-9 days'}], 'classes': [{'categories': [{'measurements': [{'value': '-0.122', 'spread': '0.0718', 'groupId': 'OG000'}, {'value': '-0.108', 'spread': '0.0766', 'groupId': 'OG001'}]}]}], 'analyses': [{'groupIds': ['OG000', 'OG001'], 'paramType': 'Least-square mean difference', 'ciNumSides': 'TWO_SIDED', 'ciPctValue': '95', 'paramValue': '-0.015', 'ciLowerLimit': '-0.027', 'ciUpperLimit': '-0.003', 'dispersionType': 'STANDARD_ERROR_OF_MEAN', 'dispersionValue': '0.0062', 'estimateComment': 'Comparison between study lenses was carried out using 2-sided 95% confidence interval of the least-square mean difference (test minus control). The non-inferiority was concluded if the upper limit of the confidence limit is below 0.05 LogMAR.', 'groupDescription': 'Ho:The test lens is non-inferior to the active comparator lens for Binocular visual performance on logMAR scale at 1-week follow-up. A non-inferiority margin of 0.05 logMAR was used.', 'statisticalMethod': 'linear mixed model', 'nonInferiorityType': 'NON_INFERIORITY_OR_EQUIVALENCE', 'statisticalComment': 'Sequence of wear,lens period and lens were included in the model as fixed effects; site, patient, period\\*patient were included as random effects.', 'nonInferiorityComment': 'Based on historical data, a minimum of 42 subjects is needed to achieve a minimum of 80% power with 0.05 type I error.'}], 'paramType': 'MEAN', 'timeFrame': 'After 5 to 9 days of lens wear', 'description': "Distance (4 meter) high contrast standard resolution (ETDRS) acuity was measured twice binocularly. Distance (4 meter) high contrast standard resolution (ETDRS) acuity was measured twice for each eye. Visual acuity describes the acuteness or sharpness of vision; the ability to perceive small details. Visual acuity is a measure of spacial resolution of the visual processing system; it's tested by requiring the person being tested to identify characters (like letters and numbers)on a chart from a set distance. LogMAR charts are used to assess visual acuity for research studies. LogMAR means Minimum Angle of Resolution. This has lead to the assertion that research is done using a logarithmic progression in size of letters on a test chart gives the most accurate visual acuity measurement. The reason for this is, unlike other charts, LogMAR chart has equal gradation between the letters on the line and the space between the lines. And, there is a fixed number of letters per line.", 'unitOfMeasure': 'LogMAR', 'dispersionType': 'Standard Deviation', 'reportingStatus': 'POSTED', 'populationDescription': 'Analysis was conducted on subjects who successfully complete the study.'}, {'type': 'PRIMARY', 'title': 'Subject Reported Overall Lens Comfort Using the Contact Lens User Evaluation (CLUE)TM Questionnaire', 'denoms': [{'units': 'Participants', 'counts': [{'value': '67', 'groupId': 'OG000'}, {'value': '67', 'groupId': 'OG001'}]}], 'groups': [{'id': 'OG000', 'title': 'Etafilcon A (Test Lens)', 'description': 'Etafilcon A toric is a daily disposable hydrogel toric lens with the addition of a wetting agent, developed for a wider ranged of prescriptions; worn 5-9 days'}, {'id': 'OG001', 'title': 'Nelfilcon A (Active Comparator)', 'description': 'An existing, daily disposable toric contact lens; worn for 5-9 days'}], 'classes': [{'categories': [{'measurements': [{'value': '56.4', 'spread': '9.12', 'groupId': 'OG000'}, {'value': '44.0', 'spread': '9.34', 'groupId': 'OG001'}]}]}], 'analyses': [{'groupIds': ['OG000', 'OG001'], 'paramType': 'Least-square mean difference', 'ciNumSides': 'TWO_SIDED', 'ciPctValue': '95', 'paramValue': '11.9', 'ciLowerLimit': '4.05', 'ciUpperLimit': '19.79', 'dispersionType': 'STANDARD_ERROR_OF_MEAN', 'dispersionValue': '3.93', 'estimateComment': 'Comparison between study lenses was carried out using 2-sided 95% confidence interval of the least-square mean difference (test minus control). The non-inferiority was concluded if the lower limit of the confidence interval is higher than -5.', 'groupDescription': 'Ho:The test lens is non-inferior to the active comparator lens for comfort at 1-week follow-up. A non-inferiority margin of -5 units was used.', 'statisticalMethod': 'linear mixed model', 'nonInferiorityType': 'NON_INFERIORITY_OR_EQUIVALENCE', 'statisticalComment': 'Sequence of lens wear, lens period and lens type were included in the model as fixed effects; and Site and patient as random effects.', 'nonInferiorityComment': 'Based on historical data, a minimum of 42 subjects is needed to achieve a minimum of 80% power with 0.05 type I error.'}], 'paramType': 'MEAN', 'timeFrame': 'After 5 to 9 days of lens wear', 'description': 'The Contact Lens User Evaluation(CLUE)TM questionnaire is a validated patient-reported outcomes questionnaire to assess patient experience attributes of soft, disposable contact lenses (comfort, vision, handling, and packaging) in a contact-lens wearing population in the US, ages 18-65. Scores follow a normal distribution with a population average score of 60 (SD 20), where higher scores indicate a more favorable/positive response. 97% of the scores fall within 0 and 120 (mean +/-3\\*SD).', 'unitOfMeasure': 'units on a scale', 'dispersionType': 'Standard Deviation', 'reportingStatus': 'POSTED', 'populationDescription': 'Analysis was conducted on subjects who successfully complete the study.'}, {'type': 'PRIMARY', 'title': 'Subject Reported Overall Quality of Vision Using the Contact Lens User Evaluation(CLUE)TM Questionnaire.', 'denoms': [{'units': 'Participants', 'counts': [{'value': '67', 'groupId': 'OG000'}, {'value': '67', 'groupId': 'OG001'}]}], 'groups': [{'id': 'OG000', 'title': 'Etafilcon A (Test Lens)', 'description': 'Etafilcon A toric is a daily disposable hydrogel toric lens with the addition of a wetting agent, developed for a wider ranged of prescriptions; worn for 5-9 days'}, {'id': 'OG001', 'title': 'Nelfilcon A (Active Comparator)', 'description': 'An existing, daily disposable toric contact lens; worn for 5-9 days.'}], 'classes': [{'categories': [{'measurements': [{'value': '52.7', 'spread': '8.64', 'groupId': 'OG000'}, {'value': '44.7', 'spread': '9.41', 'groupId': 'OG001'}]}]}], 'analyses': [{'groupIds': ['OG000', 'OG001'], 'paramType': 'least-square mean difference', 'ciNumSides': 'TWO_SIDED', 'ciPctValue': '95', 'paramValue': '7.7', 'ciLowerLimit': '0.58', 'ciUpperLimit': '14.80', 'dispersionType': 'STANDARD_ERROR_OF_MEAN', 'dispersionValue': '3.55', 'estimateComment': 'Comparison between study lenses was carried out using 2-sided 95% confidence interval of the least-square mean difference (test minus control). The non-inferiority was concluded if the lower limit of the confidence interval is higher than -5.', 'groupDescription': 'Ho:The test lens is non-inferior to the active comparator lens for overall quality of vision at 1-week follow-up. A non-inferiority margin of -5 units was used.', 'statisticalMethod': 'linear mixed model', 'nonInferiorityType': 'NON_INFERIORITY_OR_EQUIVALENCE', 'statisticalComment': 'Sequence of lens wear, lens period and lens type were included in the model as fixed effects; and site and patient as random effects.', 'nonInferiorityComment': 'Based on historical data, a minimum of 42 subjects is needed to achieve a minimum of 80% power with 0.05 type I error.'}], 'paramType': 'MEAN', 'timeFrame': 'After 5 to 9 days of lens wear', 'description': 'The Contact Lens User Evaluation(CLUE)TM questionnaire is a validated patient-reported outcomes questionnaire to assess patient experience attributes of soft, disposable contact lenses (comfort, vision, handling, and packaging) in a contact-lens wearing population in the US, ages 18-65. Scores follow a normal distribution with a population average score of 60 (SD 20), where higher scores indicate a more favorable/positive response. 97% of the scores fall within 0 and 120 (mean +/-3\\*SD).', 'unitOfMeasure': 'units on a scale', 'dispersionType': 'Standard Deviation', 'reportingStatus': 'POSTED', 'populationDescription': 'Analysis was conducted on subjects who successfully complete the study.'}]}, 'participantFlowModule': {'groups': [{'id': 'FG000', 'title': 'Etafilcon A Toric Lens First/ Nelfilcon A Toric Lens Second', 'description': 'Etafilcon A toric contact lens worn daily during first period of 5 - 9 days, then nelfilcon A toric contact lens worn daily during second period of 5 - 9 days'}, {'id': 'FG001', 'title': 'Nelfilcon A Toric Lens First/Etafilcon A Toric Lens Second', 'description': 'Nelfilcon A toric contact lens worn daily during first period of 5 - 9 days, then etafilcon A toric contact lens worn daily during second period of 5 - 9 days'}], 'periods': [{'title': 'Period 1 (5-9 Days)', 'milestones': [{'type': 'STARTED', 'achievements': [{'groupId': 'FG000', 'numSubjects': '36'}, {'groupId': 'FG001', 'numSubjects': '33'}]}, {'type': 'COMPLETED', 'achievements': [{'groupId': 'FG000', 'numSubjects': '35'}, {'groupId': 'FG001', 'numSubjects': '33'}]}, {'type': 'NOT COMPLETED', 'achievements': [{'groupId': 'FG000', 'numSubjects': '1'}, {'groupId': 'FG001', 'numSubjects': '0'}]}], 'dropWithdraws': [{'type': 'unsatisfactory lens fitting performance', 'reasons': [{'groupId': 'FG000', 'numSubjects': '1'}, {'groupId': 'FG001', 'numSubjects': '0'}]}]}, {'title': 'Period 2 (5-9 Days)', 'milestones': [{'type': 'STARTED', 'achievements': [{'groupId': 'FG000', 'numSubjects': '35'}, {'groupId': 'FG001', 'numSubjects': '33'}]}, {'type': 'COMPLETED', 'achievements': [{'groupId': 'FG000', 'numSubjects': '35'}, {'groupId': 'FG001', 'numSubjects': '32'}]}, {'type': 'NOT COMPLETED', 'achievements': [{'groupId': 'FG000', 'numSubjects': '0'}, {'groupId': 'FG001', 'numSubjects': '1'}]}], 'dropWithdraws': [{'type': 'Unsatisfactory lens fitting performance', 'reasons': [{'groupId': 'FG000', 'numSubjects': '0'}, {'groupId': 'FG001', 'numSubjects': '1'}]}]}], 'preAssignmentDetails': 'One subject failed screening, and did not enter group assignment'}, 'baselineCharacteristicsModule': {'denoms': [{'units': 'Participants', 'counts': [{'value': '69', 'groupId': 'BG000'}]}], 'groups': [{'id': 'BG000', 'title': 'All Subjects', 'description': 'All subjects who completed the study.'}], 'measures': [{'title': 'Age, Continuous', 'classes': [{'categories': [{'measurements': [{'value': '29.1', 'spread': '5.27', 'groupId': 'BG000'}]}]}], 'paramType': 'MEAN', 'unitOfMeasure': 'years', 'dispersionType': 'STANDARD_DEVIATION'}, {'title': 'Sex: Female, Male', 'classes': [{'categories': [{'title': 'Female', 'measurements': [{'value': '45', 'groupId': 'BG000'}]}, {'title': 'Male', 'measurements': [{'value': '24', 'groupId': 'BG000'}]}]}], 'paramType': 'COUNT_OF_PARTICIPANTS', 'unitOfMeasure': 'Participants'}, {'title': 'Region of Enrollment', 'classes': [{'title': 'United States', 'categories': [{'measurements': [{'value': '69', 'groupId': 'BG000'}]}]}], 'paramType': 'NUMBER', 'unitOfMeasure': 'participants'}]}}, 'protocolSection': {'designModule': {'phases': ['NA'], 'studyType': 'INTERVENTIONAL', 'designInfo': {'allocation': 'RANDOMIZED', 'maskingInfo': {'masking': 'SINGLE', 'whoMasked': ['PARTICIPANT']}, 'primaryPurpose': 'TREATMENT', 'interventionModel': 'CROSSOVER'}, 'enrollmentInfo': {'type': 'ACTUAL', 'count': 70}}, 'statusModule': {'overallStatus': 'COMPLETED', 'startDateStruct': {'date': '2010-01'}, 'expandedAccessInfo': {'hasExpandedAccess': False}, 'statusVerifiedDate': '2015-05', 'completionDateStruct': {'date': '2010-02', 'type': 'ACTUAL'}, 'lastUpdateSubmitDate': '2018-06-18', 'studyFirstSubmitDate': '2010-01-22', 'resultsFirstSubmitDate': '2011-11-03', 'studyFirstSubmitQcDate': '2010-01-22', 'lastUpdatePostDateStruct': {'date': '2018-06-19', 'type': 'ACTUAL'}, 'resultsFirstSubmitQcDate': '2013-01-04', 'studyFirstPostDateStruct': {'date': '2010-01-25', 'type': 'ESTIMATED'}, 'resultsFirstPostDateStruct': {'date': '2013-02-07', 'type': 'ESTIMATED'}, 'primaryCompletionDateStruct': {'date': '2010-02', 'type': 'ACTUAL'}}, 'outcomesModule': {'primaryOutcomes': [{'measure': 'Monocular Visual Acuity on LogMAR Scale', 'timeFrame': 'After 5 to 9 days of lens wear', 'description': "Distance (4 meter) high contrast standard resolution (ETDRS) acuity was measured twice for each eye. Visual acuity describes the acuteness or sharpness of vision; the ability to perceive small details. Visual acuity is a measure of spacial resolution of the visual processing system; it's tested by requiring the person being tested to identify characters (like letters and numbers)on a chart from a set distance. LogMAR charts are used to assess visual acuity for research studies. LogMAR means Minimum Angle of Resolution. This has lead to the assertion that research is done using a logarithmic progression in size of letters on a test chart gives the most accurate visual acuity measurement. The reason for this is, unlike other charts, LogMAR chart has equal gradation between the letters on the line and the space between the lines. And, there is a fixed number of letters per line."}, {'measure': 'Binocular Visual Acuity on LogMAR Scale', 'timeFrame': 'After 5 to 9 days of lens wear', 'description': "Distance (4 meter) high contrast standard resolution (ETDRS) acuity was measured twice binocularly. Distance (4 meter) high contrast standard resolution (ETDRS) acuity was measured twice for each eye. Visual acuity describes the acuteness or sharpness of vision; the ability to perceive small details. Visual acuity is a measure of spacial resolution of the visual processing system; it's tested by requiring the person being tested to identify characters (like letters and numbers)on a chart from a set distance. LogMAR charts are used to assess visual acuity for research studies. LogMAR means Minimum Angle of Resolution. This has lead to the assertion that research is done using a logarithmic progression in size of letters on a test chart gives the most accurate visual acuity measurement. The reason for this is, unlike other charts, LogMAR chart has equal gradation between the letters on the line and the space between the lines. And, there is a fixed number of letters per line."}, {'measure': 'Subject Reported Overall Lens Comfort Using the Contact Lens User Evaluation (CLUE)TM Questionnaire', 'timeFrame': 'After 5 to 9 days of lens wear', 'description': 'The Contact Lens User Evaluation(CLUE)TM questionnaire is a validated patient-reported outcomes questionnaire to assess patient experience attributes of soft, disposable contact lenses (comfort, vision, handling, and packaging) in a contact-lens wearing population in the US, ages 18-65. Scores follow a normal distribution with a population average score of 60 (SD 20), where higher scores indicate a more favorable/positive response. 97% of the scores fall within 0 and 120 (mean +/-3\\*SD).'}, {'measure': 'Subject Reported Overall Quality of Vision Using the Contact Lens User Evaluation(CLUE)TM Questionnaire.', 'timeFrame': 'After 5 to 9 days of lens wear', 'description': 'The Contact Lens User Evaluation(CLUE)TM questionnaire is a validated patient-reported outcomes questionnaire to assess patient experience attributes of soft, disposable contact lenses (comfort, vision, handling, and packaging) in a contact-lens wearing population in the US, ages 18-65. Scores follow a normal distribution with a population average score of 60 (SD 20), where higher scores indicate a more favorable/positive response. 97% of the scores fall within 0 and 120 (mean +/-3\\*SD).'}]}, 'oversightModule': {'oversightHasDmc': False}, 'conditionsModule': {'conditions': ['Astigmatism']}, 'descriptionModule': {'briefSummary': 'The purpose of this study is to determine the relative performance of a new daily disposable toric soft contact lens against a daily disposable toric contact lens currently available in market, specifically with regards to the comfort and vision with the lens.'}, 'eligibilityModule': {'sex': 'ALL', 'stdAges': ['ADULT'], 'maximumAge': '40 Years', 'minimumAge': '18 Years', 'healthyVolunteers': False, 'eligibilityCriteria': "Inclusion Criteria:\n\n* The subject must be between 18 and 40 years old.\n* The subject must have normal eyes.\n* The subject must appear able and willing to adhere to the instructions set forth in this clinical protocol.\n* The subject must read and sign the STATEMENT OF INFORMED CONSENT and be provided a copy of the form.\n* The subject must have a subjective distance spectacle prescription in the range of -1.75 to -5.00D in each eye.\n* The subject must manifest -1.25 to -2.00 D of refractive astigmatism in each eye.\n* The subject's refractive cylinder axis must be 180 degrees plus or minus 30 degrees in each eye.\n* The subject must be an adapted wearer of soft toric contact lenses in both eyes.\n* The subject's best visual acuity (BVA) must be better than or equal to 20/25 in each eye.\n* Subjects must already possess a wearable pair of spectacles.\n\nExclusion Criteria:\n\n* Ocular or systemic allergies or disease that may interfere with contact lens wear.\n* Systemic disease or autoimmune disease or use of medication, which may interfere with contact lens wear.\n* Clinically significant (grade 3 or 4) corneal edema, corneal vascularization, corneal staining or any other abnormality of the cornea, which may contraindicate contact lens wear.\n* Clinically significant (grade 3 or 4) tarsal abnormalities that might interfere with contact lens wear.\n* Any ocular infection.\n* Any corneal distortion resulting from previous hard or rigid gas permeable contact lens wear.\n* Pregnancy or lactation\n* Any infectious disease (e.g., hepatitis, tuberculosis) or an immunosuppressive disease (e.g., HIV).\n* Diabetes\n* Strabismus"}, 'identificationModule': {'nctId': 'NCT01055132', 'briefTitle': 'Dispensing Evaluation of New Daily Disposable Toric Soft Contact Lens.', 'organization': {'class': 'INDUSTRY', 'fullName': 'Johnson & Johnson Vision Care, Inc.'}, 'officialTitle': 'Dispensing Evaluation of New Daily Disposable Toric Soft Contact Lens.', 'orgStudyIdInfo': {'id': 'CR-1476AG'}}, 'armsInterventionsModule': {'armGroups': [{'type': 'OTHER', 'label': 'Etafilcon A toric contact lens/Nelfilcon A toric', 'description': 'Etafilcon A toric contact lens first, then nelfilcon A toric second', 'interventionNames': ['Device: Etafilcon A toric contact lens', 'Device: Nelfilcon A toric contact lens']}, {'type': 'OTHER', 'label': 'Nelfilcon A toric/ Etafilcon A toric', 'description': 'Nelfilcon A toric contact lens first, then etafilcon A toric toric second', 'interventionNames': ['Device: Etafilcon A toric contact lens', 'Device: Nelfilcon A toric contact lens']}], 'interventions': [{'name': 'Etafilcon A toric contact lens', 'type': 'DEVICE', 'description': 'contact lens to correct astigmatism', 'armGroupLabels': ['Etafilcon A toric contact lens/Nelfilcon A toric', 'Nelfilcon A toric/ Etafilcon A toric']}, {'name': 'Nelfilcon A toric contact lens', 'type': 'DEVICE', 'description': 'contact lens to correct astigmatism', 'armGroupLabels': ['Etafilcon A toric contact lens/Nelfilcon A toric', 'Nelfilcon A toric/ Etafilcon A toric']}]}, 'contactsLocationsModule': {'locations': [{'zip': '90049', 'city': 'Los Angeles', 'state': 'California', 'country': 'United States', 'geoPoint': {'lat': 34.05223, 'lon': -118.24368}}, {'zip': '32205', 'city': 'Jacksonville', 'state': 'Florida', 'country': 'United States', 'geoPoint': {'lat': 30.33218, 'lon': -81.65565}}, {'zip': '32256', 'city': 'Jacksonville', 'state': 'Florida', 'country': 'United States', 'geoPoint': {'lat': 30.33218, 'lon': -81.65565}}, {'zip': '30060', 'city': 'Marietta', 'state': 'Georgia', 'country': 'United States', 'geoPoint': {'lat': 33.9526, 'lon': -84.54993}}, {'zip': '10001', 'city': 'New York', 'state': 'New York', 'country': 'United States', 'geoPoint': {'lat': 40.71427, 'lon': -74.00597}}, {'zip': '02886', 'city': 'Warwick', 'state': 'Rhode Island', 'country': 'United States', 'geoPoint': {'lat': 41.7001, 'lon': -71.41617}}]}, 'sponsorCollaboratorsModule': {'leadSponsor': {'name': 'Johnson & Johnson Vision Care, Inc.', 'class': 'INDUSTRY'}, 'responsibleParty': {'type': 'SPONSOR'}}}}