Ignite Creation Date:
2025-12-24 @ 9:42 PM
Ignite Modification Date:
2026-02-20 @ 8:09 PM
Study NCT ID:
NCT01784432
Status:
COMPLETED
Last Update Posted:
2013-02-05
First Post:
2012-09-15
Is NOT Gene Therapy:
True
Has Adverse Events:
False
Brief Title:
Effects of Low-level Laser Therapy on Global Gene Expression of Young Males Submitted to Physical Strength Training
Sponsor:
Organization:
Raw JSON
{'hasResults': False, 'derivedSection': {'miscInfoModule': {'versionHolder': '2025-12-24'}, 'interventionBrowseModule': {'meshes': [{'id': 'D028022', 'term': 'Low-Level Light Therapy'}, {'id': 'D007834', 'term': 'Lasers'}, {'id': 'D053685', 'term': 'Laser Therapy'}], 'ancestors': [{'id': 'D013812', 'term': 'Therapeutics'}, {'id': 'D010789', 'term': 'Phototherapy'}, {'id': 'D055096', 'term': 'Optical Devices'}, {'id': 'D004864', 'term': 'Equipment and Supplies'}, {'id': 'D055618', 'term': 'Radiation Equipment and Supplies'}, {'id': 'D055011', 'term': 'Ablation Techniques'}, {'id': 'D013514', 'term': 'Surgical Procedures, Operative'}]}}, 'protocolSection': {'designModule': {'phases': ['NA'], 'studyType': 'INTERVENTIONAL', 'designInfo': {'allocation': 'RANDOMIZED', 'maskingInfo': {'masking': 'NONE'}, 'primaryPurpose': 'TREATMENT', 'interventionModel': 'FACTORIAL'}, 'enrollmentInfo': {'type': 'ACTUAL', 'count': 30}}, 'statusModule': {'overallStatus': 'COMPLETED', 'startDateStruct': {'date': '2011-01'}, 'expandedAccessInfo': {'hasExpandedAccess': False}, 'statusVerifiedDate': '2013-02', 'completionDateStruct': {'date': '2012-09', 'type': 'ACTUAL'}, 'lastUpdateSubmitDate': '2013-02-03', 'studyFirstSubmitDate': '2012-09-15', 'studyFirstSubmitQcDate': '2013-02-03', 'lastUpdatePostDateStruct': {'date': '2013-02-05', 'type': 'ESTIMATED'}, 'studyFirstPostDateStruct': {'date': '2013-02-05', 'type': 'ESTIMATED'}, 'primaryCompletionDateStruct': {'date': '2012-01', 'type': 'ACTUAL'}}, 'outcomesModule': {'otherOutcomes': [{'measure': 'Immunohistochemical analysis', 'timeFrame': '12 weeks', 'description': 'Immunohistochemical analysis to quantify morphology and cells of muscle tissue as satellite cells.'}], 'primaryOutcomes': [{'measure': 'Global gene expression by microarray analysis', 'timeFrame': '12 weeks'}], 'secondaryOutcomes': [{'measure': 'Muscle performance in leg press device', 'timeFrame': '12 weeks'}, {'measure': 'Muscle performance in isokinetic dynamometer', 'timeFrame': '12 weeks'}]}, 'oversightModule': {'oversightHasDmc': True}, 'conditionsModule': {'keywords': ['low-level laser therapy', 'muscle performance', 'strength training', 'gene expression', 'microarrays'], 'conditions': ['Healthy']}, 'referencesModule': {'references': [{'pmid': '21086010', 'type': 'BACKGROUND', 'citation': 'Ferraresi C, de Brito Oliveira T, de Oliveira Zafalon L, de Menezes Reiff RB, Baldissera V, de Andrade Perez SE, Matheucci Junior E, Parizotto NA. Effects of low level laser therapy (808 nm) on physical strength training in humans. Lasers Med Sci. 2011 May;26(3):349-58. doi: 10.1007/s10103-010-0855-0. Epub 2010 Nov 18.'}, {'pmid': '21870127', 'type': 'BACKGROUND', 'citation': 'Vieira WH, Ferraresi C, Perez SE, Baldissera V, Parizotto NA. Effects of low-level laser therapy (808 nm) on isokinetic muscle performance of young women submitted to endurance training: a randomized controlled clinical trial. Lasers Med Sci. 2012 Mar;27(2):497-504. doi: 10.1007/s10103-011-0984-0. Epub 2011 Aug 26.'}]}, 'descriptionModule': {'briefSummary': 'Muscle performance is largely influenced by modulations in gene expressions of muscle tissue. In this context, low-level laser therapy has been used to improve muscle performance in experimental models and human researches. Thereby, the investigators examined modulations on global gene expression of muscle tissue influenced by exercise associated to low-level laser therapy.', 'detailedDescription': 'This study assessed muscle performance in isokinetic dynamometry and leg press device; global gene expression of muscle tissue by microarray analysis'}, 'eligibilityModule': {'sex': 'MALE', 'stdAges': ['ADULT'], 'maximumAge': '28 Years', 'minimumAge': '18 Years', 'healthyVolunteers': True, 'eligibilityCriteria': 'Inclusion Criteria:\n\n* healthy males aged between 18 and 28 years;\n* body mass index (BMI) equal to or less than 26 kg/m2;\n* moderated pattern of physical activity\n\nExclusion Criteria:\n\n* previous injury to the femoral quadriceps or hamstring muscles (within 6 months prior to study),\n* osseous or articular disorder in the lower limbs,\n* cardiovascular system disorders,\n* systemic disease, and\n* taking prescription medicines or using dietary supplements such as muscle mass builders'}, 'identificationModule': {'nctId': 'NCT01784432', 'briefTitle': 'Effects of Low-level Laser Therapy on Global Gene Expression of Young Males Submitted to Physical Strength Training', 'organization': {'class': 'OTHER', 'fullName': 'Universidade Federal de Sao Carlos'}, 'officialTitle': 'Effects of Low-level Laser Therapy on Global Gene Expression of Young Males Submitted to Physical Strength Training', 'orgStudyIdInfo': {'id': 'CAAE: 0150.0.135.000-10'}}, 'armsInterventionsModule': {'armGroups': [{'type': 'ACTIVE_COMPARATOR', 'label': 'Low-level laser therapy and training', 'description': 'Effects of low-level laser therapy on muscle performance during physical strength training and gene expression of muscle tissue.', 'interventionNames': ['Device: Low-level laser therapy and training']}, {'type': 'ACTIVE_COMPARATOR', 'label': 'Training without low-level laser therapy', 'description': 'Effects of physical strength training without low-level laser therapy on muscle performance and gene expression of muscle tissue', 'interventionNames': ['Other: Training']}], 'interventions': [{'name': 'Low-level laser therapy and training', 'type': 'DEVICE', 'otherNames': ['Laser', 'Laser therapy', 'Low-level laser therapy'], 'armGroupLabels': ['Low-level laser therapy and training']}, {'name': 'Training', 'type': 'OTHER', 'armGroupLabels': ['Training without low-level laser therapy']}]}, 'contactsLocationsModule': {'locations': [{'zip': '13565-905', 'city': 'São Carlos', 'state': 'São Paulo', 'country': 'Brazil', 'facility': 'Federal University of São Carlos', 'geoPoint': {'lat': -22.0175, 'lon': -47.89083}}], 'overallOfficials': [{'name': 'Cleber Ferraresi, MSc', 'role': 'PRINCIPAL_INVESTIGATOR', 'affiliation': 'Universidade Federal de Sao Carlos'}, {'name': 'Nivaldo A Parizotto, PhD', 'role': 'STUDY_DIRECTOR', 'affiliation': 'Universidade Federal de Sao Carlos'}, {'name': 'Vanderlei S Bagnato, PhD', 'role': 'STUDY_DIRECTOR', 'affiliation': 'University of Sao Paulo'}]}, 'sponsorCollaboratorsModule': {'leadSponsor': {'name': 'Universidade Federal de Sao Carlos', 'class': 'OTHER'}, 'collaborators': [{'name': 'Fundação de Amparo à Pesquisa do Estado de São Paulo', 'class': 'OTHER_GOV'}, {'name': 'Centro de Pequisas de Ótica e Fotônica', 'class': 'OTHER'}, {'name': 'Faculty of Medicine of Ribeirão Preto (FMRP-USP)', 'class': 'OTHER'}, {'name': 'Fundação Hemocentro de Ribeirão Preto', 'class': 'UNKNOWN'}], 'responsibleParty': {'type': 'PRINCIPAL_INVESTIGATOR', 'investigatorTitle': 'MSc', 'investigatorFullName': 'Cleber Ferraresi', 'investigatorAffiliation': 'Universidade Federal de Sao Carlos'}}}}