Ignite Creation Date:
2025-12-24 @ 9:42 PM
Ignite Modification Date:
2026-01-01 @ 7:19 AM
Study NCT ID:
NCT05122832
Status:
COMPLETED
Last Update Posted:
2023-03-14
First Post:
2021-09-29
Is NOT Gene Therapy:
True
Has Adverse Events:
False
Brief Title:
Prevalence of NCD Risk Factors in Kazakhstan
Sponsor:
Organization:
Raw JSON
{'hasResults': False, 'derivedSection': {'miscInfoModule': {'versionHolder': '2025-12-24'}, 'conditionBrowseModule': {'meshes': [{'id': 'D000073296', 'term': 'Noncommunicable Diseases'}], 'ancestors': [{'id': 'D020969', 'term': 'Disease Attributes'}, {'id': 'D010335', 'term': 'Pathologic Processes'}, {'id': 'D013568', 'term': 'Pathological Conditions, Signs and Symptoms'}]}, 'interventionBrowseModule': {'meshes': [{'id': 'D006403', 'term': 'Hematologic Tests'}, {'id': 'D013147', 'term': 'Spirometry'}], 'ancestors': [{'id': 'D019411', 'term': 'Clinical Laboratory Techniques'}, {'id': 'D019937', 'term': 'Diagnostic Techniques and Procedures'}, {'id': 'D003933', 'term': 'Diagnosis'}, {'id': 'D008919', 'term': 'Investigative Techniques'}, {'id': 'D012129', 'term': 'Respiratory Function Tests'}, {'id': 'D003948', 'term': 'Diagnostic Techniques, Respiratory System'}]}}, 'protocolSection': {'designModule': {'studyType': 'OBSERVATIONAL', 'designInfo': {'timePerspective': 'CROSS_SECTIONAL', 'observationalModel': 'OTHER'}, 'enrollmentInfo': {'type': 'ACTUAL', 'count': 20400}, 'patientRegistry': False}, 'statusModule': {'overallStatus': 'COMPLETED', 'startDateStruct': {'date': '2021-10-23', 'type': 'ACTUAL'}, 'expandedAccessInfo': {'hasExpandedAccess': False}, 'statusVerifiedDate': '2023-03', 'completionDateStruct': {'date': '2022-08-20', 'type': 'ACTUAL'}, 'lastUpdateSubmitDate': '2023-03-13', 'studyFirstSubmitDate': '2021-09-29', 'studyFirstSubmitQcDate': '2021-11-04', 'lastUpdatePostDateStruct': {'date': '2023-03-14', 'type': 'ACTUAL'}, 'studyFirstPostDateStruct': {'date': '2021-11-17', 'type': 'ACTUAL'}, 'primaryCompletionDateStruct': {'date': '2022-08-20', 'type': 'ACTUAL'}}, 'outcomesModule': {'primaryOutcomes': [{'measure': 'tobacco use', 'timeFrame': '1 year', 'description': 'currently smoke tobacco, currently smoke tobacco daily, age started smoking, daily smokers smoking manufactured cigarettes'}, {'measure': 'alcohol consumption', 'timeFrame': '1 year', 'description': 'lifetime abstainers, past 12 month abstainers, currently drink (drank alcohol in the past 30 days), heavy episodic drinking (6 or more drinks on any occasion in the past 30 days).'}, {'measure': 'physical activity', 'timeFrame': '1 year', 'description': 'insufficient physical activity (defined as \\< 150 minutes of moderate-intensity activity per week, or equivalent), physical activity on average per day (minutes), not engaging in vigorous activity.'}, {'measure': 'unhealthy diet', 'timeFrame': '1 year', 'description': 'days fruit consumed in a typical week, servings of fruit consumed on average per day, days vegetables consumed in a typical week, servings of vegetables consumed on average per day, less than 5 servings of fruit and/or vegetables on average per day, always or often add salt or salty sauce to their food before eating or as they are eating, always or often eat processed foods high in salt.'}, {'measure': 'BMI', 'timeFrame': '1 year', 'description': 'overweight (BMI ≥ 25 kg/m2), obese (BMI ≥ 30 kg/m2), normal weight'}, {'measure': 'raised blood pressure', 'timeFrame': '1 year', 'description': 'systolic blood pressure - SBP (mmHg), including those currently on medication for raised BP, diastolic blood pressure - DBP (mmHg), including those currently on medication for raised BP, raised BP (SBP ≥ 140 and/or DBP ≥ 90 mmHg or currently on medication for raised BP), raised BP (SBP ≥ 140 and/or DBP ≥ 90 mmHg or currently on medication for raised BP) who are not currently on medication for raised BP.'}, {'measure': 'raised blood glucose', 'timeFrame': '1 year', 'description': 'fasting blood glucose, including those currently on medication for raised blood glucose, impaired fasting glycaemia (plasma venous value ≥6.1 mmol/L (110 mg/dl) and \\<7.0 mmol/L (126 mg/dl)), raised fasting blood glucose (plasma venous value ≥ 7.0 mmol/L (126 mg/dl)) or currently on medication for raised blood glucose.'}, {'measure': 'abnormal blood lipids', 'timeFrame': '1 year', 'description': 'total blood cholesterol, including those currently on medication for raised cholesterol, raised total cholesterol,'}]}, 'oversightModule': {'isFdaRegulatedDrug': False, 'isFdaRegulatedDevice': False}, 'conditionsModule': {'conditions': ['Non-Communicable Chronic Diseases']}, 'referencesModule': {'references': [{'pmid': '38420037', 'type': 'DERIVED', 'citation': 'Baspakova A, Abitova AZ, Mussin NM, Kaliyev AA, Yerimbetova G, Zhumagaliyeva S, Ashimova Z, Zhilisbayeva KR, Umbetova AA, Nurtazina AU, Tamadon A. Sex differentials in the prevalence of behavioral risk factors and non-communicable diseases in adult populations of West Kazakhstan. Front Public Health. 2024 Feb 14;12:1333887. doi: 10.3389/fpubh.2024.1333887. eCollection 2024.'}, {'pmid': '37679536', 'type': 'DERIVED', 'citation': 'Nursultanova L, Kabulbayev K, Ospanova D, Tazhiyeva A, Datkhayev U, Saliev T, Tanabayeva S, Fakhradiyev I. Prevalence of chronic kidney disease in Kazakhstan: evidence from a national cross-sectional study. Sci Rep. 2023 Sep 7;13(1):14710. doi: 10.1038/s41598-023-42031-2.'}]}, 'descriptionModule': {'briefSummary': 'This is a cross-sectional study that aims to study the prevalence of risk factors of noncommunicable diseases in people aged 18 to 69 years using the standardized and adopted STEPS questionnaire in the Republic of Kazakhstan.', 'detailedDescription': 'The WHO STEPwise Approach to NCD Risk Factor Surveillance (STEPS) is a simple, standardized method for collecting, analysing and disseminating data on key NCD risk factors in countries. The survey instrument covers key behavioral risk factors: tobacco use, alcohol consumption, physical activity, unhealthy diet, as well as key biological risk factors: overweight and obesity, raised blood pressure, raised blood glucose, and abnormal blood lipids.'}, 'eligibilityModule': {'sex': 'ALL', 'stdAges': ['ADULT', 'OLDER_ADULT'], 'maximumAge': '69 Years', 'minimumAge': '18 Years', 'samplingMethod': 'PROBABILITY_SAMPLE', 'studyPopulation': 'All ethnic groups in Kazakhstan', 'eligibilityCriteria': 'Inclusion Criteria:\n\n* Age Limits 18-69 years'}, 'identificationModule': {'nctId': 'NCT05122832', 'briefTitle': 'Prevalence of NCD Risk Factors in Kazakhstan', 'organization': {'class': 'OTHER', 'fullName': 'Asfendiyarov Kazakh National Medical University'}, 'officialTitle': 'Preventive and Personalized Medicine (2021-2023)', 'orgStudyIdInfo': {'id': '1197'}}, 'armsInterventionsModule': {'armGroups': [{'label': 'The study Group', 'description': 'Population of Kazakhstan', 'interventionNames': ['Diagnostic Test: Blood test', 'Diagnostic Test: STEPwise Approach to NCD Risk Factor Surveillance (STEPS)', 'Diagnostic Test: Spirometry']}], 'interventions': [{'name': 'Blood test', 'type': 'DIAGNOSTIC_TEST', 'description': 'Glucose Glycosylated hemoglobin Triglycerides Total cholesterol HDL Cholesterol LDL Cholesterol Creatinine COVID-19 Antibody IgM to N protein SARS-Cov-2 (Abbott) COVID-19 Antibody IgG to N protein SARS-Cov-2 (Abbott)', 'armGroupLabels': ['The study Group']}, {'name': 'STEPwise Approach to NCD Risk Factor Surveillance (STEPS)', 'type': 'DIAGNOSTIC_TEST', 'description': 'The WHO STEPwise Approach to NCD Risk Factor Surveillance (STEPS) is a simple, standardized method for collecting, analysing and disseminating data on key NCD risk factors in countries. The survey instrument covers key behavioral risk factors: tobacco use, alcohol consumption, physical activity, unhealthy diet, as well as key biological risk factors: overweight and obesity, raised blood pressure, raised blood glucose, and abnormal blood lipids. Through the use of expanded modules, the survey instrument can be expanded to cover a range of topics beyond these risk factors, such as oral health, sexual health and road safety.', 'armGroupLabels': ['The study Group']}, {'name': 'Spirometry', 'type': 'DIAGNOSTIC_TEST', 'description': 'Spirometry is a common office test used to assess how well your lungs work by measuring how much air you inhale, how much you exhale and how quickly you exhale.', 'armGroupLabels': ['The study Group']}]}, 'contactsLocationsModule': {'locations': [{'zip': '050020', 'city': 'Almaty', 'country': 'Kazakhstan', 'facility': 'Kazakhstan', 'geoPoint': {'lat': 43.25249, 'lon': 76.9115}}], 'overallOfficials': [{'name': 'Timur M Saliev', 'role': 'PRINCIPAL_INVESTIGATOR', 'affiliation': 'S.D. Asfendiyarov Kazakh National Medical University'}, {'name': 'Ildar Fakhradiyev, PhD', 'role': 'STUDY_CHAIR', 'affiliation': 'S.D. Asfendiyarov Kazakh National Medical University'}, {'name': 'Mukhtar B Kulimbet, MD/MSc', 'role': 'STUDY_DIRECTOR', 'affiliation': 'S.D. Asfendiyarov Kazakh National Medical University'}, {'name': 'Zhumaly A Kauyzbay, PhD, AP', 'role': 'PRINCIPAL_INVESTIGATOR', 'affiliation': 'Joint Stock Company - South Kazakhstan Medical Academy'}, {'name': 'Samat S Saparbayev, PhD', 'role': 'PRINCIPAL_INVESTIGATOR', 'affiliation': 'West Kazakhstan Marat Ospanov Medical University'}, {'name': 'Alma U Nurtazina, MD/PhD', 'role': 'PRINCIPAL_INVESTIGATOR', 'affiliation': 'NCJSC Semey Medical University'}, {'name': 'Bayan A Ainabekova, MD/DMSc', 'role': 'PRINCIPAL_INVESTIGATOR', 'affiliation': 'NCJSC Astana Medical University'}, {'name': 'Anar A Turmukhambetova, DMSc', 'role': 'PRINCIPAL_INVESTIGATOR', 'affiliation': 'NCJSC Karaganda Medical University'}, {'name': 'Maksut K Kulzhanov, DMSc', 'role': 'PRINCIPAL_INVESTIGATOR', 'affiliation': 'Kazakhstan\'s Medical University "KSPH"'}]}, 'sponsorCollaboratorsModule': {'leadSponsor': {'name': 'Asfendiyarov Kazakh National Medical University', 'class': 'OTHER'}, 'responsibleParty': {'type': 'PRINCIPAL_INVESTIGATOR', 'investigatorTitle': 'Head of the Laboratory of Experimental Medicine', 'investigatorFullName': 'Ildar Fakhradiyev', 'investigatorAffiliation': 'Asfendiyarov Kazakh National Medical University'}}}}