Ignite Creation Date:
2025-12-24 @ 9:24 PM
Ignite Modification Date:
2025-12-28 @ 12:28 AM
Study NCT ID:
NCT04389632
Status:
RECRUITING
Last Update Posted:
2025-12-09
First Post:
2020-05-12
Is NOT Gene Therapy:
True
Has Adverse Events:
False
Brief Title:
A Study of Sigvotatug Vedotin in Advanced Solid Tumors
Sponsor:
Organization:
Raw JSON
{'hasResults': False, 'derivedSection': {'miscInfoModule': {'versionHolder': '2025-12-24'}, 'conditionBrowseModule': {'meshes': [{'id': 'D002289', 'term': 'Carcinoma, Non-Small-Cell Lung'}, {'id': 'D000077195', 'term': 'Squamous Cell Carcinoma of Head and Neck'}, {'id': 'D000077277', 'term': 'Esophageal Squamous Cell Carcinoma'}, {'id': 'C562730', 'term': 'Adenocarcinoma Of Esophagus'}, {'id': 'D010051', 'term': 'Ovarian Neoplasms'}, {'id': 'D001749', 'term': 'Urinary Bladder Neoplasms'}, {'id': 'D002583', 'term': 'Uterine Cervical Neoplasms'}, {'id': 'D013274', 'term': 'Stomach Neoplasms'}, {'id': 'D004938', 'term': 'Esophageal Neoplasms'}], 'ancestors': [{'id': 'D002283', 'term': 'Carcinoma, Bronchogenic'}, {'id': 'D001984', 'term': 'Bronchial Neoplasms'}, {'id': 'D008175', 'term': 'Lung Neoplasms'}, {'id': 'D012142', 'term': 'Respiratory Tract Neoplasms'}, {'id': 'D013899', 'term': 'Thoracic Neoplasms'}, {'id': 'D009371', 'term': 'Neoplasms by Site'}, {'id': 'D009369', 'term': 'Neoplasms'}, {'id': 'D008171', 'term': 'Lung Diseases'}, {'id': 'D012140', 'term': 'Respiratory Tract Diseases'}, {'id': 'D002294', 'term': 'Carcinoma, Squamous Cell'}, {'id': 'D002277', 'term': 'Carcinoma'}, {'id': 'D009375', 'term': 'Neoplasms, Glandular and Epithelial'}, {'id': 'D009370', 'term': 'Neoplasms by Histologic Type'}, {'id': 'D006258', 'term': 'Head and Neck Neoplasms'}, {'id': 'D018307', 'term': 'Neoplasms, Squamous Cell'}, {'id': 'D005770', 'term': 'Gastrointestinal Neoplasms'}, {'id': 'D004067', 'term': 'Digestive System Neoplasms'}, {'id': 'D004066', 'term': 'Digestive System Diseases'}, {'id': 'D004935', 'term': 'Esophageal Diseases'}, {'id': 'D005767', 'term': 'Gastrointestinal Diseases'}, {'id': 'D004701', 'term': 'Endocrine Gland Neoplasms'}, {'id': 'D010049', 'term': 'Ovarian Diseases'}, {'id': 'D000291', 'term': 'Adnexal Diseases'}, {'id': 'D005831', 'term': 'Genital Diseases, Female'}, {'id': 'D052776', 'term': 'Female Urogenital Diseases'}, {'id': 'D005261', 'term': 'Female Urogenital Diseases and Pregnancy Complications'}, {'id': 'D000091642', 'term': 'Urogenital Diseases'}, {'id': 'D005833', 'term': 'Genital Neoplasms, Female'}, {'id': 'D014565', 'term': 'Urogenital Neoplasms'}, {'id': 'D000091662', 'term': 'Genital Diseases'}, {'id': 'D004700', 'term': 'Endocrine System Diseases'}, {'id': 'D006058', 'term': 'Gonadal Disorders'}, {'id': 'D014571', 'term': 'Urologic Neoplasms'}, {'id': 'D001745', 'term': 'Urinary Bladder Diseases'}, {'id': 'D014570', 'term': 'Urologic Diseases'}, {'id': 'D052801', 'term': 'Male Urogenital Diseases'}, {'id': 'D014594', 'term': 'Uterine Neoplasms'}, {'id': 'D002577', 'term': 'Uterine Cervical Diseases'}, {'id': 'D014591', 'term': 'Uterine Diseases'}, {'id': 'D013272', 'term': 'Stomach Diseases'}]}, 'interventionBrowseModule': {'meshes': [{'id': 'C582435', 'term': 'pembrolizumab'}, {'id': 'D002945', 'term': 'Cisplatin'}, {'id': 'D016190', 'term': 'Carboplatin'}], 'ancestors': [{'id': 'D017606', 'term': 'Chlorine Compounds'}, {'id': 'D007287', 'term': 'Inorganic Chemicals'}, {'id': 'D017672', 'term': 'Nitrogen Compounds'}, {'id': 'D017671', 'term': 'Platinum Compounds'}, {'id': 'D056831', 'term': 'Coordination Complexes'}, {'id': 'D009930', 'term': 'Organic Chemicals'}]}}, 'protocolSection': {'designModule': {'phases': ['PHASE1'], 'studyType': 'INTERVENTIONAL', 'designInfo': {'allocation': 'NA', 'maskingInfo': {'masking': 'NONE'}, 'primaryPurpose': 'TREATMENT', 'interventionModel': 'SEQUENTIAL'}, 'enrollmentInfo': {'type': 'ESTIMATED', 'count': 1006}}, 'statusModule': {'overallStatus': 'RECRUITING', 'startDateStruct': {'date': '2020-06-08', 'type': 'ACTUAL'}, 'expandedAccessInfo': {'hasExpandedAccess': False}, 'statusVerifiedDate': '2025-12', 'completionDateStruct': {'date': '2029-03-22', 'type': 'ESTIMATED'}, 'lastUpdateSubmitDate': '2025-12-08', 'studyFirstSubmitDate': '2020-05-12', 'studyFirstSubmitQcDate': '2020-05-12', 'lastUpdatePostDateStruct': {'date': '2025-12-09', 'type': 'ESTIMATED'}, 'studyFirstPostDateStruct': {'date': '2020-05-15', 'type': 'ACTUAL'}, 'primaryCompletionDateStruct': {'date': '2027-06-16', 'type': 'ESTIMATED'}}, 'outcomesModule': {'primaryOutcomes': [{'measure': 'Number of participants with adverse events (AEs)', 'timeFrame': 'Through 30-37 days following last dose of sigvotatug vedotin. For participants receiving pembrolizumab up to 90 days after last dose of pembrolizumab; up to 3 years', 'description': 'Any untoward medical occurrence in a clinical investigational participant administered a medicinal product and which does not necessarily have a causal relationship with this treatment.'}, {'measure': 'Number of patients with laboratory abnormalities', 'timeFrame': 'Through 30-37 days following last dose of sigvotatug vedotin; up to 3 years'}, {'measure': 'Number of participants with dose-limiting toxicities (DLTs)', 'timeFrame': 'Through 30-37 days following last dose of sigvotatug vedotin; up to 3 years'}], 'secondaryOutcomes': [{'measure': 'Confirmed objective response rate (ORR) per Response Evaluation Criteria in Solid Tumors (RECIST) v1.1 by investigator assessment', 'timeFrame': 'Up to approximately 3 years', 'description': 'The proportion of participants with complete response (CR) or partial response (PR) which is subsequently confirmed as assessed according to RECIST v1.1.'}, {'measure': 'Duration of objective response (DOR) per RECIST v1.1 by investigator assessment', 'timeFrame': 'Up to approximately 3 years', 'description': 'The time from the first documentation of objective response (CR or PR that is subsequently confirmed) to the first documentation of progressive disease (PD) or to death due to any cause'}, {'measure': 'Progression-free survival (PFS) per RECIST v1.1 by investigator assessment', 'timeFrame': 'Up to approximately 3 years', 'description': 'The time from the start of any study treatment to the first documentation of PD, or death due to any cause'}, {'measure': 'Overall survival (OS)', 'timeFrame': 'Up to approximately 3 years', 'description': 'The time from the start of any study treatment to the date of death due to any cause'}, {'measure': 'Area under the concentration-time curve (AUC)', 'timeFrame': 'Through 30-37 days following last dose of sigvotatug vedotin; up to 3 years', 'description': 'Pharmacokinetic (PK) endpoint'}, {'measure': 'Concentration at the end of infusion (Ceoi)', 'timeFrame': 'Through 30-37 days following last dose of sigvotatug vedotin; up to 3 years', 'description': 'PK endpoint'}, {'measure': 'Maximum observed concentration (Cmax)', 'timeFrame': 'Through 30-37 days following last dose of sigvotatug vedotin; up to 3 years', 'description': 'PK endpoint'}, {'measure': 'Time to maximum observed concentration (Tmax)', 'timeFrame': 'Through 30-37 days following last dose of sigvotatug vedotin; up to 3 years', 'description': 'PK endpoint'}, {'measure': 'Trough concentration (Ctrough)', 'timeFrame': 'Through 30-37 days following last dose of sigvotatug vedotin; up to 3 years', 'description': 'PK endpoint'}, {'measure': 'Apparent terminal elimination half-life (t1/2)', 'timeFrame': 'Through 30-37 days following last dose of sigvotatug vedotin; up to 3 years', 'description': 'PK endpoint'}, {'measure': 'Number of participants with antidrug antibodies (ADAs)', 'timeFrame': 'Through 30-37 days following last dose of sigvotatug vedotin; up to 3 years'}]}, 'oversightModule': {'oversightHasDmc': True, 'isFdaRegulatedDrug': True, 'isFdaRegulatedDevice': False}, 'conditionsModule': {'keywords': ['NSCLC', 'HNSCC', 'cSCC', 'ESCC', 'EAC', 'GEJ', 'HGSOC', 'Advanced HER2-Negative Breast Cancer', 'High Grade Serous Ovarian Cancer', 'Non-Small Cell Lung Cancer', 'Head and Neck Squamous Cell Cancer', 'Esophageal Cancer', 'Bladder Cancer', 'Cervical Cancer', 'Gastric Cancer', 'Seattle Genetics'], 'conditions': ['Carcinoma, Non-Small Cell Lung', 'Squamous Cell Carcinoma of Head and Neck', 'HER2 Negative Breast Neoplasms', 'Esophageal Squamous Cell Carcinoma', 'Esophageal Adenocarcinoma', 'Gastroesophageal Junction Adenocarcinoma', 'Ovarian Neoplasms', 'Cutaneous Squamous Cell Cancer', 'Exocrine Pancreatic Adenocarcinoma', 'Urinary Bladder Neoplasms', 'Uterine Cervical Neoplasms', 'Stomach Neoplasms']}, 'referencesModule': {'references': [{'pmid': '37619980', 'type': 'DERIVED', 'citation': 'Lyon RP, Jonas M, Frantz C, Trueblood ES, Yumul R, Westendorf L, Hale CJ, Stilwell JL, Yeddula N, Snead KM, Kumar V, Patilea-Vrana GI, Klussman K, Ryan MC. SGN-B6A: A New Vedotin Antibody-Drug Conjugate Directed to Integrin Beta-6 for Multiple Carcinoma Indications. Mol Cancer Ther. 2023 Dec 1;22(12):1444-1453. doi: 10.1158/1535-7163.MCT-22-0817.'}], 'seeAlsoLinks': [{'url': 'https://pmiform.com/clinical-trial-info-request?StudyID=SGNB6A-001', 'label': 'To obtain contact information for a study center near you, click here.'}]}, 'descriptionModule': {'briefSummary': 'This trial will look at a drug called sigvotatug vedotin (SGN-B6A) alone and with pembrolizumab, with or without chemotherapy, to find out whether it is safe for people who have solid tumors. It will study sigvotatug vedotin to find out what its side effects are. A side effect is anything the drug does besides treating cancer. It will also study whether sigvotatug vedotin works to treat solid tumors.\n\nThe study will have four parts.\n\n* Part A of the study will find out how much sigvotatug vedotin should be given to participants.\n* Part B will use the dose found in Part A to find out how safe sigvotatug vedotin is and if it works to treat solid tumors.\n* Part C of the study will find out how safe sigvotatug vedotin is in combination with these other drugs.\n* Part D will include people who have not received treatment. This part of the study will find out how safe sigvotatug vedotin is in combination with these other drugs and if these combinations work to treat solid tumors.\n* In Parts C and D, participants will receive sigvotatug vedotin with either:\n\n * Pembrolizumab or,\n * Pembrolizumab and carboplatin, or\n * Pembrolizumab and cisplatin.'}, 'eligibilityModule': {'sex': 'ALL', 'stdAges': ['ADULT', 'OLDER_ADULT'], 'minimumAge': '18 Years', 'healthyVolunteers': False, 'eligibilityCriteria': "Inclusion Criteria:\n\n* Disease indication\n\n * Participants must have histologically or cytologically confirmed metastatic or unresectable solid malignancy within one of the tumor types listed below (dependent on study part).\n\n * Non-small cell lung cancer (NSCLC)\n * Head and neck squamous cell cancer (HNSCC)\n * Advanced HER2-negative breast cancer\n * Esophageal squamous cell carcinoma (ESCC)\n * Esophageal/Gastro-esophageal junction adenocarcinoma (EAC/GEJ)\n * Cutaneous squamous cell cancer (cSCC)\n * Exocrine pancreatic adenocarcinoma\n * Bladder cancer\n * Cervical cancer\n * Gastric cancer\n * High grade serous ovarian cancer (HGSOC)\n * Part A only: Participants must have disease that is relapsed or refractory or be intolerant to standard-of-care therapies and should have no appropriate standard-of-care therapeutic options.\n * Part B only: Participants must have disease that is relapsed or refractory or be intolerant to standard-of-care therapies. Participants must have received platinum-based therapy and a PD-1/PD-(L)1 inhibitor, if applicable and available.\n * Part C only: For pembrolizumab combination cohorts, participants must be eligible for pembrolizumab per local standard of care. For pembrolizumab with cisplatin or carboplatin, participants must be eligible for both pembrolizumab and the platinum agent per local standard of care. Participants must be treatment naïve for locally advanced or metastatic systemic therapy (prior definitively intended or \\[neo\\]adjuvant therapy is allowed).\n * Part D only: Participants must be treatment naïve for locally advanced or metastatic systemic therapy.\n* Participants enrolled in the following study parts should have a tumor site accessible for biopsy and agree to biopsy as follows:\n\n * Disease-specific expansion cohorts (Part B and Part D): A baseline fresh tumor biopsy is required. An archival biopsy collected within 90 days prior to first dose of study drug may be used.\n * Biology expansion cohort: pretreatment biopsy and on-treatment (Cycle 1) biopsy\n* An Eastern Cooperative Oncology Group (ECOG) Performance Status of 0 or 1\n* Measurable disease per the RECIST v1.1 at baseline\n\nExclusion Criteria\n\n* History of another malignancy within 3 years before first dose of study drug, or any evidence of residual disease from a previously diagnosed malignancy. Exceptions are malignancies with a negligible risk of metastasis or death.\n* Known active central nervous system metastases. Participants with previously treated brain metastases may participate provided they:\n\n * are clinically stable for at least 4 weeks prior to study entry after brain metastasis treatment,\n * have no new or enlarging brain metastases, and\n * are off of corticosteroids prescribed for symptoms associated with brain metastases for at least 7 days prior to first dose of study drug.\n * In Part D, participants with untreated, asymptomatic CNS metastases smaller than 1 cm may be enrolled without definitive treatment as long as they have no neurological symptoms, no or minimal surrounding edema, and no requirements for corticosteroids.\n* Carcinomatous meningitis\n* Previous receipt of an MMAE-containing agent or an agent targeting integrin beta-6\n* Pre-existing neuropathy Grade 1 or greater per the National Cancer Institute's Common Terminology Criteria for Adverse Events, version 5.0 (NCI CTCAE v5.0) for Parts C and D cohorts with cisplatin or carboplatin; Grade 2 or greater per the NCI CTCAE v5.0 for all other cohorts\n* Any uncontrolled Grade 3 or higher (per NCI CTCAE v5.0) viral, bacterial, or fungal infection within 2 weeks prior to the first dose of sigvotatug vedotin.\n\n * Routine antimicrobial prophylaxis is permitted\n* Grade ≥3 pulmonary disease unrelated to underlying malignancy. This includes clinically severe pulmonary function compromise resulting from clinically significant pulmonary illnesses\n* Part C and D: Prior therapy with a PD-1 inhibitor, anti-PD-(L)1, or anti PD-L2 agent or with an agent directed to another stimulatory or co-inhibitory T-cell receptor and was discontinued from that treatment due to a Grade 3 or higher immune-mediated adverse event (IMAE).\n* History of noninfectious interstitial lung disease (ILD) or pneumonitis that required steroids, current ILD or pneumonitis, or suspected ILD or pneumonitis that cannot be ruled out by imaging at screening\n* Known diffusing capacity of the lung for carbon monoxide (DLCO; adjusted for hemoglobin) \\<50% predicted\n* Investigator site staff directly involved in the conduct of the study and their family members, site staff otherwise supervised by the investigator, and sponsor and sponsor delegate employees directly involved in the conduct of the study and their family members."}, 'identificationModule': {'nctId': 'NCT04389632', 'briefTitle': 'A Study of Sigvotatug Vedotin in Advanced Solid Tumors', 'organization': {'class': 'INDUSTRY', 'fullName': 'Seagen Inc.'}, 'officialTitle': 'A Phase 1 Study of Sigvotatug Vedotin in Advanced Solid Tumors', 'orgStudyIdInfo': {'id': 'SGNB6A-001'}, 'secondaryIdInfos': [{'id': 'C5751001', 'type': 'OTHER', 'domain': 'Alias Study Number'}, {'id': '2023-508469-34-00', 'type': 'REGISTRY', 'domain': 'CTIS (EU)'}]}, 'armsInterventionsModule': {'armGroups': [{'type': 'EXPERIMENTAL', 'label': 'Part A: Dose escalation', 'description': 'sigvotatug vedotin monotherapy', 'interventionNames': ['Drug: sigvotatug vedotin']}, {'type': 'EXPERIMENTAL', 'label': 'Part B: Dose expansion', 'description': 'sigvotatug vedotin monotherapy', 'interventionNames': ['Drug: sigvotatug vedotin']}, {'type': 'EXPERIMENTAL', 'label': 'Part C: sigvotatug vedotin combination therapy in NSCLC, HNSCC, ESCC', 'description': 'sigvotatug vedotin + pembrolizumab +/- (carboplatin or cisplatin)', 'interventionNames': ['Drug: sigvotatug vedotin', 'Drug: pembrolizumab', 'Drug: cisplatin', 'Drug: carboplatin']}, {'type': 'EXPERIMENTAL', 'label': 'Part D: sigvotatug vedotin combination therapy in 1L NSCLC', 'description': 'sigvotatug vedotin + pembrolizumab +/- (carboplatin)', 'interventionNames': ['Drug: sigvotatug vedotin', 'Drug: pembrolizumab', 'Drug: carboplatin']}, {'type': 'EXPERIMENTAL', 'label': 'Part D: sigvotatug vedotin combination therapy in 1L HNSCC', 'description': 'sigvotatug vedotin + pembrolizumab +/- (carboplatin or cisplatin)', 'interventionNames': ['Drug: sigvotatug vedotin', 'Drug: pembrolizumab', 'Drug: cisplatin', 'Drug: carboplatin']}], 'interventions': [{'name': 'sigvotatug vedotin', 'type': 'DRUG', 'otherNames': ['SGN-B6A', 'PF-08046047'], 'description': 'Administered into the vein (IV; intravenously)', 'armGroupLabels': ['Part A: Dose escalation', 'Part B: Dose expansion', 'Part C: sigvotatug vedotin combination therapy in NSCLC, HNSCC, ESCC', 'Part D: sigvotatug vedotin combination therapy in 1L HNSCC', 'Part D: sigvotatug vedotin combination therapy in 1L NSCLC']}, {'name': 'pembrolizumab', 'type': 'DRUG', 'otherNames': ['Keytruda'], 'description': '200mg every 3 weeks or 400mg every 6 weeks, given by IV', 'armGroupLabels': ['Part C: sigvotatug vedotin combination therapy in NSCLC, HNSCC, ESCC', 'Part D: sigvotatug vedotin combination therapy in 1L HNSCC', 'Part D: sigvotatug vedotin combination therapy in 1L NSCLC']}, {'name': 'cisplatin', 'type': 'DRUG', 'description': '75 mg/m2 every 3 weeks, given by IV', 'armGroupLabels': ['Part C: sigvotatug vedotin combination therapy in NSCLC, HNSCC, ESCC', 'Part D: sigvotatug vedotin combination therapy in 1L HNSCC']}, {'name': 'carboplatin', 'type': 'DRUG', 'description': 'AUC 5 mg/mL per min every 3 weeks, given by IV', 'armGroupLabels': ['Part C: sigvotatug vedotin combination therapy in NSCLC, HNSCC, ESCC', 'Part D: sigvotatug vedotin combination therapy in 1L HNSCC', 'Part D: sigvotatug vedotin combination therapy in 1L NSCLC']}]}, 'contactsLocationsModule': {'locations': [{'zip': '99508', 'city': 'Anchorage', 'state': 'Alaska', 'status': 'NOT_YET_RECRUITING', 'country': 'United States', 'facility': 'Alaska Oncology and Hematology', 'geoPoint': {'lat': 61.21806, 'lon': -149.90028}}, {'zip': '72703', 'city': 'Fayetteville', 'state': 'Arkansas', 'status': 'RECRUITING', 'country': 'United States', 'facility': 'Highlands Oncology Group', 'geoPoint': {'lat': 36.06258, 'lon': -94.15743}}, {'zip': '72758', 'city': 'Rogers', 'state': 'Arkansas', 'status': 'RECRUITING', 'country': 'United States', 'facility': 'Highlands Oncology Group', 'geoPoint': {'lat': 36.33202, 'lon': -94.11854}}, {'zip': '72762', 'city': 'Springdale', 'state': 'Arkansas', 'status': 'RECRUITING', 'country': 'United States', 'facility': 'Highlands Oncology Group', 'geoPoint': {'lat': 36.18674, 'lon': -94.12881}}, {'zip': '92805', 'city': 'Anaheim', 'state': 'California', 'status': 'RECRUITING', 'country': 'United States', 'facility': 'Providence Medical Foundation', 'geoPoint': {'lat': 33.83529, 'lon': -117.9145}}, {'zip': '92835', 'city': 'Fullerton', 'state': 'California', 'status': 'RECRUITING', 'country': 'United States', 'facility': 'Providence Medical Foundation', 'geoPoint': {'lat': 33.87029, 'lon': -117.92534}}, {'zip': '92835', 'city': 'Fullerton', 'state': 'California', 'status': 'RECRUITING', 'country': 'United States', 'facility': 'Providence St. Jude Medical Center Virginia K Crosson and Infusion Center', 'geoPoint': {'lat': 33.87029, 'lon': -117.92534}}, {'zip': '90720', 'city': 'Los Alamitos', 'state': 'California', 'status': 'NOT_YET_RECRUITING', 'country': 'United States', 'facility': 'Cancer and Blood Research Center, LLC', 'geoPoint': {'lat': 33.80307, 'lon': -118.07256}}, {'zip': '90720', 'city': 'Los Alamitos', 'state': 'California', 'status': 'NOT_YET_RECRUITING', 'country': 'United States', 'facility': 'Cancer and Blood Specialty Clinic', 'geoPoint': {'lat': 33.80307, 'lon': -118.07256}}, {'zip': '90095', 'city': 'Los Angeles', 'state': 'California', 'status': 'RECRUITING', 'country': 'United States', 'facility': 'Ronald Reagan UCLA Medical Center', 'geoPoint': {'lat': 34.05223, 'lon': -118.24368}}, {'zip': '90095', 'city': 'Los Angeles', 'state': 'California', 'status': 'RECRUITING', 'country': 'United States', 'facility': 'The Regents of the University of California', 'geoPoint': {'lat': 34.05223, 'lon': -118.24368}}, {'zip': '90095', 'city': 'Los Angeles', 'state': 'California', 'status': 'RECRUITING', 'country': 'United States', 'facility': 'UCLA Department of Medicine-Hematology/Oncology', 'geoPoint': {'lat': 34.05223, 'lon': -118.24368}}, {'zip': '90404', 'city': 'Santa Monica', 'state': 'California', 'status': 'RECRUITING', 'country': 'United States', 'facility': 'UCLA Department of Medicine - Hematology & Oncology', 'geoPoint': {'lat': 34.01949, 'lon': -118.49138}}, {'zip': '90505', 'city': 'Torrance', 'state': 'California', 'status': 'NOT_YET_RECRUITING', 'country': 'United States', 'facility': 'Cancer AND Blood Specialty Clinic', 'geoPoint': {'lat': 33.83585, 'lon': -118.34063}}, {'zip': '33913', 'city': 'Fort Myers', 'state': 'Florida', 'status': 'RECRUITING', 'country': 'United States', 'facility': 'American Oncology Partners, PA. a Florida professional service corporation, d/b/a Vista Oncology', 'geoPoint': {'lat': 26.62168, 'lon': -81.84059}}, {'zip': '33916', 'city': 'Fort Myers', 'state': 'Florida', 'status': 'RECRUITING', 'country': 'United States', 'facility': 'Florida Cancer Specialists & Research Institute, LLC', 'geoPoint': {'lat': 26.62168, 'lon': -81.84059}}, {'zip': '33916', 'city': 'Fort Myers', 'state': 'Florida', 'status': 'RECRUITING', 'country': 'United States', 'facility': 'Florida cancer Specialists', 'geoPoint': {'lat': 26.62168, 'lon': -81.84059}}, {'zip': '33021', 'city': 'Hollywood', 'state': 'Florida', 'status': 'RECRUITING', 'country': 'United States', 'facility': 'Memorial Cancer Institute', 'geoPoint': {'lat': 26.0112, 'lon': -80.14949}}, {'zip': '33021', 'city': 'Hollywood', 'state': 'Florida', 'status': 'RECRUITING', 'country': 'United States', 'facility': 'Memorial Healthcare System', 'geoPoint': {'lat': 26.0112, 'lon': -80.14949}}, {'zip': '32827', 'city': 'Orlando', 'state': 'Florida', 'status': 'RECRUITING', 'country': 'United States', 'facility': 'Florida cancer Specialists', 'geoPoint': {'lat': 28.53834, 'lon': -81.37924}}, {'zip': '33028', 'city': 'Pembroke Pines', 'state': 'Florida', 'status': 'RECRUITING', 'country': 'United States', 'facility': 'Memorial Cancer Institute at Memorial Hospital West', 'geoPoint': {'lat': 26.00315, 'lon': -80.22394}}, {'zip': '33028', 'city': 'Pembroke Pines', 'state': 'Florida', 'status': 'RECRUITING', 'country': 'United States', 'facility': 'Memorial Hospital West', 'geoPoint': {'lat': 26.00315, 'lon': -80.22394}}, {'zip': '60409', 'city': 'Calumet City', 'state': 'Illinois', 'status': 'RECRUITING', 'country': 'United States', 'facility': 'Ingalls Family Care Center', 'geoPoint': {'lat': 41.61559, 'lon': -87.52949}}, {'zip': '60611', 'city': 'Chicago', 'state': 'Illinois', 'status': 'RECRUITING', 'country': 'United States', 'facility': 'UChicago Medicine - River East', 'geoPoint': {'lat': 41.85003, 'lon': -87.65005}}, {'zip': '60637', 'city': 'Chicago', 'state': 'Illinois', 'status': 'RECRUITING', 'country': 'United States', 'facility': 'The University Of Chicago', 'geoPoint': {'lat': 41.85003, 'lon': -87.65005}}, {'zip': '60637', 'city': 'Chicago', 'state': 'Illinois', 'status': 'RECRUITING', 'country': 'United States', 'facility': 'University of Chicago Medical Center', 'geoPoint': {'lat': 41.85003, 'lon': -87.65005}}, {'zip': '60422', 'city': 'Flossmoor', 'state': 'Illinois', 'status': 'RECRUITING', 'country': 'United States', 'facility': 'UChicago Medicine at Ingalls - Flossmoor', 'geoPoint': {'lat': 41.54281, 'lon': -87.68477}}, {'zip': '60426', 'city': 'Harvey', 'state': 'Illinois', 'status': 'RECRUITING', 'country': 'United States', 'facility': 'UChicago Medicine Ingalls Memorial', 'geoPoint': {'lat': 41.61003, 'lon': -87.64671}}, {'zip': '60451', 'city': 'New Lenox', 'state': 'Illinois', 'status': 'RECRUITING', 'country': 'United States', 'facility': 'University of Chicago Comprehensive Cancer Center at Silver Cross Hospital', 'geoPoint': {'lat': 41.51198, 'lon': -87.96561}}, {'zip': '60462', 'city': 'Orland Park', 'state': 'Illinois', 'status': 'RECRUITING', 'country': 'United States', 'facility': 'The University of Chicago Medicine Center for Advanced Care Orland Park', 'geoPoint': {'lat': 41.63031, 'lon': -87.85394}}, {'zip': '62702', 'city': 'Springfield', 'state': 'Illinois', 'status': 'RECRUITING', 'country': 'United States', 'facility': 'Southern Illinois University - Simmons Cancer Institute', 'geoPoint': {'lat': 39.80172, 'lon': -89.64371}}, {'zip': '62702', 'city': 'Springfield', 'state': 'Illinois', 'status': 'RECRUITING', 'country': 'United States', 'facility': 'Springfield Clinic Radiology - 800 Building', 'geoPoint': {'lat': 39.80172, 'lon': -89.64371}}, {'zip': '62702', 'city': 'Springfield', 'state': 'Illinois', 'status': 'RECRUITING', 'country': 'United States', 'facility': 'Springfield Clinic', 'geoPoint': {'lat': 39.80172, 'lon': -89.64371}}, {'zip': '62703', 'city': 'Springfield', 'state': 'Illinois', 'status': 'RECRUITING', 'country': 'United States', 'facility': 'Springfield Clinic Main Campus', 'geoPoint': {'lat': 39.80172, 'lon': -89.64371}}, {'zip': '62703', 'city': 'Springfield', 'state': 'Illinois', 'status': 'RECRUITING', 'country': 'United States', 'facility': 'Springfield Clinic Radiology - Main Campus', 'geoPoint': {'lat': 39.80172, 'lon': -89.64371}}, {'zip': '62781', 'city': 'Springfield', 'state': 'Illinois', 'status': 'RECRUITING', 'country': 'United States', 'facility': 'Springfield Memorial Hospital', 'geoPoint': {'lat': 39.80172, 'lon': -89.64371}}, {'zip': '60477', 'city': 'Tinley Park', 'state': 'Illinois', 'status': 'RECRUITING', 'country': 'United States', 'facility': 'UChicago Medicine at Ingalls - Tinley Park', 'geoPoint': {'lat': 41.57337, 'lon': -87.78449}}, {'zip': '46307', 'city': 'Crown Point', 'state': 'Indiana', 'status': 'RECRUITING', 'country': 'United States', 'facility': 'UChicago Medicine - Northwest Indiana', 'geoPoint': {'lat': 41.41698, 'lon': -87.36531}}, {'zip': '46804', 'city': 'Fort Wayne', 'state': 'Indiana', 'status': 'RECRUITING', 'country': 'United States', 'facility': 'Fort Wayne Medical Oncology and Hematology, Inc', 'geoPoint': {'lat': 41.1306, 'lon': -85.12886}}, {'zip': '46219', 'city': 'Indianapolis', 'state': 'Indiana', 'status': 'RECRUITING', 'country': 'United States', 'facility': 'Community Health Network, Inc', 'geoPoint': {'lat': 39.76838, 'lon': -86.15804}}, {'zip': '46227', 'city': 'Indianapolis', 'state': 'Indiana', 'status': 'RECRUITING', 'country': 'United States', 'facility': 'Community Health Network, Inc.', 'geoPoint': {'lat': 39.76838, 'lon': -86.15804}}, {'zip': '46250', 'city': 'Indianapolis', 'state': 'Indiana', 'status': 'RECRUITING', 'country': 'United States', 'facility': 'Community Health Network Investigational Drug Services', 'geoPoint': {'lat': 39.76838, 'lon': -86.15804}}, {'zip': '46250', 'city': 'Indianapolis', 'state': 'Indiana', 'status': 'RECRUITING', 'country': 'United States', 'facility': 'Community Health Network, Inc.', 'geoPoint': {'lat': 39.76838, 'lon': -86.15804}}, {'zip': '46256', 'city': 'Indianapolis', 'state': 'Indiana', 'status': 'RECRUITING', 'country': 'United States', 'facility': 'Community Health Network', 'geoPoint': {'lat': 39.76838, 'lon': -86.15804}}, {'zip': '66205', 'city': 'Fairway', 'state': 'Kansas', 'status': 'RECRUITING', 'country': 'United States', 'facility': 'The University of Kansas Cancer Center, Investigational Drug Services', 'geoPoint': {'lat': 39.02223, 'lon': -94.6319}}, {'zip': '66205', 'city': 'Fairway', 'state': 'Kansas', 'status': 'RECRUITING', 'country': 'United States', 'facility': 'The University of Kansas Clinical Research Center', 'geoPoint': {'lat': 39.02223, 'lon': -94.6319}}, {'zip': '66160', 'city': 'Kansas City', 'state': 'Kansas', 'status': 'RECRUITING', 'country': 'United States', 'facility': 'The University of Kansas Hospital', 'geoPoint': {'lat': 39.11417, 'lon': -94.62746}}, {'zip': '66160', 'city': 'Kansas City', 'state': 'Kansas', 'status': 'RECRUITING', 'country': 'United States', 'facility': 'The University of Kansas Medical Center Medical Office Building', 'geoPoint': {'lat': 39.11417, 'lon': -94.62746}}, {'zip': '66160', 'city': 'Kansas City', 'state': 'Kansas', 'status': 'RECRUITING', 'country': 'United States', 'facility': 'University of Kansas Hospital Cambridge North Tower A', 'geoPoint': {'lat': 39.11417, 'lon': -94.62746}}, {'zip': '66160', 'city': 'Kansas City', 'state': 'Kansas', 'status': 'RECRUITING', 'country': 'United States', 'facility': 'University of Kansas Medical Center Research Institute', 'geoPoint': {'lat': 39.11417, 'lon': -94.62746}}, {'zip': '66211', 'city': 'Overland Park', 'state': 'Kansas', 'status': 'RECRUITING', 'country': 'United States', 'facility': 'The University of Kansas Cancer Center - Indian Creek Campus', 'geoPoint': {'lat': 38.98223, 'lon': -94.67079}}, {'zip': '66205', 'city': 'Westwood', 'state': 'Kansas', 'status': 'RECRUITING', 'country': 'United States', 'facility': 'The University of Kansas Cancer Center - Westwood', 'geoPoint': {'lat': 39.04056, 'lon': -94.6169}}, {'zip': '66205', 'city': 'Westwood', 'state': 'Kansas', 'status': 'RECRUITING', 'country': 'United States', 'facility': 'University of Kansas Cancer Center', 'geoPoint': {'lat': 39.04056, 'lon': -94.6169}}, {'zip': '02114', 'city': 'Boston', 'state': 'Massachusetts', 'status': 'RECRUITING', 'country': 'United States', 'facility': 'Massachusetts General Hospital', 'geoPoint': {'lat': 42.35843, 'lon': -71.05977}}, {'zip': '02115', 'city': 'Boston', 'state': 'Massachusetts', 'status': 'RECRUITING', 'country': 'United States', 'facility': "Brigham & Women's Hospital", 'geoPoint': {'lat': 42.35843, 'lon': -71.05977}}, {'zip': '02215', 'city': 'Boston', 'state': 'Massachusetts', 'status': 'RECRUITING', 'country': 'United States', 'facility': 'Beth Israel Deaconess Medical Center,East Campus Research Pharmacy', 'geoPoint': {'lat': 42.35843, 'lon': -71.05977}}, {'zip': '02215', 'city': 'Boston', 'state': 'Massachusetts', 'status': 'RECRUITING', 'country': 'United States', 'facility': 'Beth Israel Deaconess Medical Center', 'geoPoint': {'lat': 42.35843, 'lon': -71.05977}}, {'zip': '02215', 'city': 'Boston', 'state': 'Massachusetts', 'status': 'RECRUITING', 'country': 'United States', 'facility': 'Dana Farber Cancer Institute', 'geoPoint': {'lat': 42.35843, 'lon': -71.05977}}, {'zip': '02459', 'city': 'Newton', 'state': 'Massachusetts', 'status': 'RECRUITING', 'country': 'United States', 'facility': 'Dana-Farber Cancer Institute - Chestnut Hill', 'geoPoint': {'lat': 42.33704, 'lon': -71.20922}}, {'zip': '55433', 'city': 'Coon Rapids', 'state': 'Minnesota', 'status': 'RECRUITING', 'country': 'United States', 'facility': 'Allina Health Cancer Institute - Mercy Hospital', 'geoPoint': {'lat': 45.11997, 'lon': -93.28773}}, {'zip': '55407', 'city': 'Minneapolis', 'state': 'Minnesota', 'status': 'RECRUITING', 'country': 'United States', 'facility': 'Allina Health Cancer Institute - Abbott Northwestern Hospital', 'geoPoint': {'lat': 44.97997, 'lon': -93.26384}}, {'zip': '55102', 'city': 'Saint Paul', 'state': 'Minnesota', 'status': 'RECRUITING', 'country': 'United States', 'facility': 'Allina Health Cancer Institute', 'geoPoint': {'lat': 44.94441, 'lon': -93.09327}}, {'zip': '89169', 'city': 'Las Vegas', 'state': 'Nevada', 'status': 'RECRUITING', 'country': 'United States', 'facility': 'Comprehensive Cancer Centers of Nevada', 'geoPoint': {'lat': 36.17497, 'lon': -115.13722}}, {'zip': '11702', 'city': 'Babylon', 'state': 'New York', 'status': 'RECRUITING', 'country': 'United States', 'facility': 'North Shore Hematology Oncology Associates P.C. DBA New York Cancer and Blood Specialists', 'geoPoint': {'lat': 40.69566, 'lon': -73.32568}}, {'zip': '11210', 'city': 'Brooklyn', 'state': 'New York', 'status': 'RECRUITING', 'country': 'United States', 'facility': 'North Shore Hematology Oncology Associates P.C. DBA New York Cancer and Blood Specialists', 'geoPoint': {'lat': 40.6501, 'lon': -73.94958}}, {'zip': '11042', 'city': 'New Hyde Park', 'state': 'New York', 'status': 'RECRUITING', 'country': 'United States', 'facility': 'North Shore Hematology Oncology Associates P.C. DBA New York Cancer and Blood Specialists', 'geoPoint': {'lat': 40.7351, 'lon': -73.68791}}, {'zip': '10028', 'city': 'New York', 'state': 'New York', 'status': 'RECRUITING', 'country': 'United States', 'facility': 'North Shore Hematology Oncology Associates P.C. DBA New York Cancer and Blood Specialists', 'geoPoint': {'lat': 40.71427, 'lon': -74.00597}}, {'zip': '10032', 'city': 'New York', 'state': 'New York', 'status': 'RECRUITING', 'country': 'United States', 'facility': 'Columbia University Irving Medical Center', 'geoPoint': {'lat': 40.71427, 'lon': -74.00597}}, {'zip': '11772', 'city': 'Patchogue', 'state': 'New York', 'status': 'RECRUITING', 'country': 'United States', 'facility': 'North Shore Hematology Oncology Associates P.C. DBA New York Cancer and Blood Specialists', 'geoPoint': {'lat': 40.76565, 'lon': -73.01511}}, {'zip': '11776', 'city': 'Port Jefferson Station', 'state': 'New York', 'status': 'RECRUITING', 'country': 'United States', 'facility': 'North Shore Hematology Oncology Associates P.C. DBA New York Cancer and Blood Specialists', 'geoPoint': {'lat': 40.92538, 'lon': -73.04733}}, {'zip': '11901', 'city': 'Riverhead', 'state': 'New York', 'status': 'RECRUITING', 'country': 'United States', 'facility': 'North Shore Hematology Oncology Associates P.C. DBA New York Cancer and Blood Specialists', 'geoPoint': {'lat': 40.91704, 'lon': -72.66204}}, {'zip': '11967', 'city': 'Shirley', 'state': 'New York', 'status': 'RECRUITING', 'country': 'United States', 'facility': 'North Shore Hematology Oncology Associates P.C. DBA New York Cancer and Blood Specialists', 'geoPoint': {'lat': 40.80149, 'lon': -72.8676}}, {'zip': '10469', 'city': 'The Bronx', 'state': 'New York', 'status': 'RECRUITING', 'country': 'United States', 'facility': 'North Shore Hematology Oncology Associates P.C. DBA New York Cancer and Blood Specialists', 'geoPoint': {'lat': 40.84985, 'lon': -73.86641}}, {'zip': '44106', 'city': 'Cleveland', 'state': 'Ohio', 'status': 'ACTIVE_NOT_RECRUITING', 'country': 'United States', 'facility': 'University Hospitals Cleveland Medical Center', 'geoPoint': {'lat': 41.4995, 'lon': -81.69541}}, {'zip': '73104', 'city': 'Oklahoma City', 'state': 'Oklahoma', 'status': 'RECRUITING', 'country': 'United States', 'facility': 'OU Health University of Oklahoma Medical Center', 'geoPoint': {'lat': 35.46756, 'lon': -97.51643}}, {'zip': '73104', 'city': 'Oklahoma City', 'state': 'Oklahoma', 'status': 'RECRUITING', 'country': 'United States', 'facility': 'Stephenson Cancer Center (chemo location)', 'geoPoint': {'lat': 35.46756, 'lon': -97.51643}}, {'zip': '73104', 'city': 'Oklahoma City', 'state': 'Oklahoma', 'status': 'RECRUITING', 'country': 'United States', 'facility': 'University of Oklahoma Health Science Center', 'geoPoint': {'lat': 35.46756, 'lon': -97.51643}}, {'zip': '97213', 'city': 'Portland', 'state': 'Oregon', 'status': 'RECRUITING', 'country': 'United States', 'facility': 'Providence Cancer Institute Franz Clinic', 'geoPoint': {'lat': 45.52345, 'lon': -122.67621}}, {'zip': '97225', 'city': 'Portland', 'state': 'Oregon', 'status': 'RECRUITING', 'country': 'United States', 'facility': 'Providence Oncology and Hematology Care Clinic - Westside', 'geoPoint': {'lat': 45.52345, 'lon': -122.67621}}, {'zip': '97225', 'city': 'Portland', 'state': 'Oregon', 'status': 'RECRUITING', 'country': 'United States', 'facility': 'Providence St. Vincent Medical Center- Investigational Drug Services', 'geoPoint': {'lat': 45.52345, 'lon': -122.67621}}, {'zip': '97225', 'city': 'Portland', 'state': 'Oregon', 'status': 'RECRUITING', 'country': 'United States', 'facility': 'Providence St. Vincent Medical Center', 'geoPoint': {'lat': 45.52345, 'lon': -122.67621}}, {'zip': '57104', 'city': 'Sioux Falls', 'state': 'South Dakota', 'status': 'RECRUITING', 'country': 'United States', 'facility': 'Sanford Cancer Center', 'geoPoint': {'lat': 43.54369, 'lon': -96.72796}}, {'zip': '57105', 'city': 'Sioux Falls', 'state': 'South Dakota', 'status': 'RECRUITING', 'country': 'United States', 'facility': 'Sanford USD Medical Center', 'geoPoint': {'lat': 43.54369, 'lon': -96.72796}}, {'zip': '37203', 'city': 'Nashville', 'state': 'Tennessee', 'status': 'RECRUITING', 'country': 'United States', 'facility': 'US Oncology Research LLC', 'geoPoint': {'lat': 36.16589, 'lon': -86.78444}}, {'zip': '77024', 'city': 'Houston', 'state': 'Texas', 'status': 'RECRUITING', 'country': 'United States', 'facility': 'Oncology Consultants, PA', 'geoPoint': {'lat': 29.76328, 'lon': -95.36327}}, {'zip': '77030', 'city': 'Houston', 'state': 'Texas', 'status': 'RECRUITING', 'country': 'United States', 'facility': 'Oncology Consultants, PA.', 'geoPoint': {'lat': 29.76328, 'lon': -95.36327}}, {'zip': '77030', 'city': 'Houston', 'state': 'Texas', 'status': 'RECRUITING', 'country': 'United States', 'facility': 'The University of Texas M.D. Anderson Cancer Center', 'geoPoint': {'lat': 29.76328, 'lon': -95.36327}}, {'zip': '75063', 'city': 'Irving', 'state': 'Texas', 'status': 'RECRUITING', 'country': 'United States', 'facility': 'US Oncology Investigational Product Center (IPC)', 'geoPoint': {'lat': 32.81402, 'lon': -96.94889}}, {'zip': '77581', 'city': 'Pearland', 'state': 'Texas', 'status': 'NOT_YET_RECRUITING', 'country': 'United States', 'facility': 'Houston Medical Imaging', 'geoPoint': {'lat': 29.56357, 'lon': -95.28605}}, {'zip': '78229', 'city': 'San Antonio', 'state': 'Texas', 'status': 'ACTIVE_NOT_RECRUITING', 'country': 'United States', 'facility': 'South Texas Accelerated Research Therapeutics, LLC', 'geoPoint': {'lat': 29.42412, 'lon': -98.49363}}, {'zip': '75701', 'city': 'Tyler', 'state': 'Texas', 'status': 'NOT_YET_RECRUITING', 'country': 'United States', 'facility': 'UT Health East Texas HOPE Cancer Center', 'geoPoint': {'lat': 32.35126, 'lon': -95.30106}}, {'zip': '75708', 'city': 'Tyler', 'state': 'Texas', 'status': 'NOT_YET_RECRUITING', 'country': 'United States', 'facility': 'UT Health East Texas Hope Cancer Center', 'geoPoint': {'lat': 32.35126, 'lon': -95.30106}}, {'zip': '77598', 'city': 'Webster', 'state': 'Texas', 'status': 'NOT_YET_RECRUITING', 'country': 'United States', 'facility': 'Tranquil Clinical Research', 'geoPoint': {'lat': 29.53773, 'lon': -95.11826}}, {'zip': '22031', 'city': 'Fairfax', 'state': 'Virginia', 'status': 'RECRUITING', 'country': 'United States', 'facility': 'Virginia Cancer Specialists', 'geoPoint': {'lat': 38.84622, 'lon': -77.30637}}, {'zip': '98026', 'city': 'Edmonds', 'state': 'Washington', 'status': 'RECRUITING', 'country': 'United States', 'facility': 'Swedish Cancer Institute - Edmonds Campus', 'geoPoint': {'lat': 47.81065, 'lon': -122.37736}}, {'zip': '98026', 'city': 'Edmonds', 'state': 'Washington', 'status': 'RECRUITING', 'country': 'United States', 'facility': 'Swedish Cancer Institute Edmonds Campus', 'geoPoint': {'lat': 47.81065, 'lon': -122.37736}}, {'zip': '98502', 'city': 'Olympia', 'state': 'Washington', 'status': 'RECRUITING', 'country': 'United States', 'facility': 'American Oncology Network Vista Oncology Division-West office', 'geoPoint': {'lat': 47.04491, 'lon': -122.90169}}, {'zip': '98506', 'city': 'Olympia', 'state': 'Washington', 'status': 'RECRUITING', 'country': 'United States', 'facility': 'American Oncology Network Vista Oncology Division-East office', 'geoPoint': {'lat': 47.04491, 'lon': -122.90169}}, {'zip': '98104', 'city': 'Seattle', 'state': 'Washington', 'status': 'RECRUITING', 'country': 'United States', 'facility': 'Swedish Cancer Institute', 'geoPoint': {'lat': 47.60621, 'lon': -122.33207}}, {'zip': '98122', 'city': 'Seattle', 'state': 'Washington', 'status': 'RECRUITING', 'country': 'United States', 'facility': 'Swedish Medical Center', 'geoPoint': {'lat': 47.60621, 'lon': -122.33207}}, {'zip': '98405', 'city': 'Tacoma', 'state': 'Washington', 'status': 'RECRUITING', 'country': 'United States', 'facility': 'Exigent Research, LLC', 'geoPoint': {'lat': 47.25288, 'lon': -122.44429}}, {'zip': '98405', 'city': 'Tacoma', 'state': 'Washington', 'status': 'NOT_YET_RECRUITING', 'country': 'United States', 'facility': 'Northwest Medical Specialities, PLLC', 'geoPoint': {'lat': 47.25288, 'lon': -122.44429}}, {'zip': '49100', 'city': 'Angers', 'status': 'RECRUITING', 'country': 'France', 'facility': "Center Hospitalier Universitaire d' Angers", 'geoPoint': {'lat': 47.47156, 'lon': -0.55202}}, {'zip': '54519', 'city': 'Moselle', 'status': 'NOT_YET_RECRUITING', 'country': 'France', 'facility': 'Institut de Cancérologie de Lorraine'}, {'zip': '06189', 'city': 'Nice', 'status': 'RECRUITING', 'country': 'France', 'facility': 'Centre de Lutte contre le Cancer (CLCC) - Centre Antoine Lacassagne', 'geoPoint': {'lat': 43.70313, 'lon': 7.26608}}, {'zip': '86021', 'city': 'Poitiers', 'status': 'RECRUITING', 'country': 'France', 'facility': 'Centre Hospitalier Universitaire de Poitiers', 'geoPoint': {'lat': 46.58261, 'lon': 0.34348}}, {'zip': '94805.', 'city': 'Villejuif', 'status': 'RECRUITING', 'country': 'France', 'facility': "lnstitut Gustave Roussy, Departement d'lnnovation Therapeutique et d'Essais Precoces (DITEP)", 'geoPoint': {'lat': 48.7939, 'lon': 2.35992}}, {'zip': '10408', 'city': 'Goyang-si', 'state': 'Gyeonggi-do', 'status': 'RECRUITING', 'country': 'South Korea', 'facility': 'National Cancer Center', 'geoPoint': {'lat': 37.65639, 'lon': 126.835}}, {'zip': '28644', 'city': 'Cheongju-si', 'status': 'RECRUITING', 'country': 'South Korea', 'facility': 'Chungbuk National University Hospital', 'geoPoint': {'lat': 36.63722, 'lon': 127.48972}}, {'zip': '03722', 'city': 'Seoul', 'status': 'RECRUITING', 'country': 'South Korea', 'facility': 'Severance Hospital Yonsei University Health System', 'geoPoint': {'lat': 37.566, 'lon': 126.9784}}, {'zip': '06351', 'city': 'Seoul', 'status': 'NOT_YET_RECRUITING', 'country': 'South Korea', 'facility': 'Samsung Medical Center', 'geoPoint': {'lat': 37.566, 'lon': 126.9784}}, {'zip': '06591', 'city': 'Seoul', 'status': 'RECRUITING', 'country': 'South Korea', 'facility': 'The Catholic University of Korea', 'geoPoint': {'lat': 37.566, 'lon': 126.9784}}, {'zip': '07061', 'city': 'Seoul', 'status': 'RECRUITING', 'country': 'South Korea', 'facility': 'Seoul National University Boramae Medical Center', 'geoPoint': {'lat': 37.566, 'lon': 126.9784}}, {'zip': '08308', 'city': 'Seoul', 'status': 'NOT_YET_RECRUITING', 'country': 'South Korea', 'facility': 'Korea University Guro Hospital', 'geoPoint': {'lat': 37.566, 'lon': 126.9784}}, {'zip': '28050', 'city': 'Madrid', 'state': 'Agrigento', 'status': 'RECRUITING', 'country': 'Spain', 'facility': 'Farmacia Ensayos Hospital HM Universitario Sanchinarro', 'geoPoint': {'lat': 40.4165, 'lon': -3.70256}}, {'zip': '03203', 'city': 'Elche', 'state': 'Alicante', 'status': 'RECRUITING', 'country': 'Spain', 'facility': 'Elche General University Hospital', 'geoPoint': {'lat': 38.26218, 'lon': -0.70107}}, {'zip': '39008', 'city': 'Santander', 'state': 'Cantabria', 'status': 'RECRUITING', 'country': 'Spain', 'facility': 'Equipo de Farmacia Oncológica- Ensayos Clínicos Servicio de Farmacia Hospital Universitario Marqués', 'geoPoint': {'lat': 43.46589, 'lon': -3.80493}}, {'zip': '08023', 'city': 'Barcelona', 'state': 'Catalonia', 'status': 'RECRUITING', 'country': 'Spain', 'facility': 'Hospital HM Nou Delfos', 'geoPoint': {'lat': 41.38879, 'lon': 2.15899}}, {'zip': '08023', 'city': 'Barcelona', 'state': 'OTH', 'status': 'RECRUITING', 'country': 'Spain', 'facility': 'NEXT Oncology Barcelona - IOB - Hospital Quironsalud Barcelona', 'geoPoint': {'lat': 41.38879, 'lon': 2.15899}}, {'zip': '08023', 'city': 'Barcelona', 'status': 'RECRUITING', 'country': 'Spain', 'facility': 'Farmacia Ensayos clínicos, Unidad START Barcelona', 'geoPoint': {'lat': 41.38879, 'lon': 2.15899}}, {'zip': '08023', 'city': 'Barcelona', 'status': 'RECRUITING', 'country': 'Spain', 'facility': 'Hospital HM Nou Delfos - START Barcelona', 'geoPoint': {'lat': 41.38879, 'lon': 2.15899}}, {'zip': '08023', 'city': 'Barcelona', 'status': 'RECRUITING', 'country': 'Spain', 'facility': 'Hospital Quiron Salud Barcelona', 'geoPoint': {'lat': 41.38879, 'lon': 2.15899}}, {'zip': '08035', 'city': 'Barcelona', 'status': 'RECRUITING', 'country': 'Spain', 'facility': 'Area general-Planta Baixa | Unitat d\'investigacio en terapia Molecular del Cancer "la Caixa"', 'geoPoint': {'lat': 41.38879, 'lon': 2.15899}}, {'zip': '08035', 'city': 'Barcelona', 'status': 'RECRUITING', 'country': 'Spain', 'facility': "Hospital Vall d'Hebron", 'geoPoint': {'lat': 41.38879, 'lon': 2.15899}}, {'zip': '03203', 'city': 'Elche', 'status': 'RECRUITING', 'country': 'Spain', 'facility': 'Elche General University Hospital', 'geoPoint': {'lat': 38.26218, 'lon': -0.70107}}, {'zip': '10407', 'city': 'Jerez de la Frontera', 'status': 'RECRUITING', 'country': 'Spain', 'facility': 'Hospital Universitario De Jerez', 'geoPoint': {'lat': 36.68645, 'lon': -6.13606}}, {'zip': '10407', 'city': 'Jerez de la Frontera', 'status': 'RECRUITING', 'country': 'Spain', 'facility': 'UGC Farmacia Ensayos clinicos - Hospital Universitario de Jerez', 'geoPoint': {'lat': 36.68645, 'lon': -6.13606}}, {'zip': '11407', 'city': 'Jerez de la Frontera', 'status': 'RECRUITING', 'country': 'Spain', 'facility': 'Hospital Universitario de Jerez', 'geoPoint': {'lat': 36.68645, 'lon': -6.13606}}, {'zip': '28015', 'city': 'Madrid', 'status': 'RECRUITING', 'country': 'Spain', 'facility': 'Fundación de Investigación Hm Hospitales, C.I.F. G-83643841', 'geoPoint': {'lat': 40.4165, 'lon': -3.70256}}, {'zip': '28034', 'city': 'Madrid', 'status': 'RECRUITING', 'country': 'Spain', 'facility': 'Hospital Universitario Ramon y Cajal', 'geoPoint': {'lat': 40.4165, 'lon': -3.70256}}, {'zip': '28034', 'city': 'Madrid', 'status': 'RECRUITING', 'country': 'Spain', 'facility': 'Servicio de Radiologia Hospital Universitario Ramon y Cajal', 'geoPoint': {'lat': 40.4165, 'lon': -3.70256}}, {'zip': '28041', 'city': 'Madrid', 'status': 'RECRUITING', 'country': 'Spain', 'facility': 'Hospital Universitario 12 de Octubre', 'geoPoint': {'lat': 40.4165, 'lon': -3.70256}}, {'zip': '28041', 'city': 'Madrid', 'status': 'RECRUITING', 'country': 'Spain', 'facility': 'Hospital Universitario 12 Octubre', 'geoPoint': {'lat': 40.4165, 'lon': -3.70256}}, {'zip': '28050', 'city': 'Madrid', 'status': 'RECRUITING', 'country': 'Spain', 'facility': 'Hospital HM Sanchinarro, START-Madrid-CIOCC', 'geoPoint': {'lat': 40.4165, 'lon': -3.70256}}, {'zip': '129004', 'city': 'Málaga', 'status': 'RECRUITING', 'country': 'Spain', 'facility': 'Quironsalud Malaga', 'geoPoint': {'lat': 36.72016, 'lon': -4.42034}}, {'zip': '7000', 'city': 'Chur', 'status': 'RECRUITING', 'country': 'Switzerland', 'facility': 'Kantonsspital Graubunden', 'geoPoint': {'lat': 46.84986, 'lon': 9.53287}}, {'zip': '1011', 'city': 'Lausanne', 'status': 'RECRUITING', 'country': 'Switzerland', 'facility': 'University Hospital Lausanne CHUV', 'geoPoint': {'lat': 46.516, 'lon': 6.63282}}, {'zip': 'CH-1011', 'city': 'Lausanne', 'status': 'RECRUITING', 'country': 'Switzerland', 'facility': 'CHUV - Service de pharmacie BH-04, Essais cliniques', 'geoPoint': {'lat': 46.516, 'lon': 6.63282}}, {'zip': '80756', 'city': 'Kaohsiung City', 'state': 'R.o.c.', 'status': 'RECRUITING', 'country': 'Taiwan', 'facility': 'Kaohsiung Medical University Hospital', 'geoPoint': {'lat': 22.61626, 'lon': 120.31333}}, {'zip': '100, R.O.C', 'city': 'Taipei', 'status': 'NOT_YET_RECRUITING', 'country': 'Taiwan', 'facility': 'National Taiwan University Hospital', 'geoPoint': {'lat': 25.05306, 'lon': 121.52639}}, {'zip': '11217', 'city': 'Taipei', 'status': 'RECRUITING', 'country': 'Taiwan', 'facility': 'Taipei Veterans General Hospital.', 'geoPoint': {'lat': 25.05306, 'lon': 121.52639}}, {'zip': 'SM2 5PT', 'city': 'Sutton', 'state': 'Queensland', 'status': 'RECRUITING', 'country': 'United Kingdom', 'facility': 'The Royal Marsden Hospital (Surrey)', 'geoPoint': {'lat': 51.35, 'lon': -0.2}}, {'zip': 'SM2 5PT', 'city': 'Sutton', 'state': 'Surrey', 'status': 'RECRUITING', 'country': 'United Kingdom', 'facility': 'Royal Marsden Hospital', 'geoPoint': {'lat': 51.35, 'lon': -0.2}}, {'zip': 'B15 2TH', 'city': 'Birmingham', 'status': 'RECRUITING', 'country': 'United Kingdom', 'facility': 'Queen Elizabeth Hospital', 'geoPoint': {'lat': 52.48142, 'lon': -1.89983}}, {'zip': 'B15 2TH', 'city': 'Birmingham', 'status': 'RECRUITING', 'country': 'United Kingdom', 'facility': 'University Hospitals Birmingham NHS Foundation Trust', 'geoPoint': {'lat': 52.48142, 'lon': -1.89983}}, {'zip': 'SW3 6JJ', 'city': 'London', 'status': 'RECRUITING', 'country': 'United Kingdom', 'facility': 'The Royal Marsden NHS Foundation Trust', 'geoPoint': {'lat': 51.50853, 'lon': -0.12574}}, {'zip': 'W1G 6AD', 'city': 'London', 'status': 'RECRUITING', 'country': 'United Kingdom', 'facility': 'Sarah Cannon Research Institute', 'geoPoint': {'lat': 51.50853, 'lon': -0.12574}}, {'zip': 'W1G 7AF', 'city': 'London', 'status': 'RECRUITING', 'country': 'United Kingdom', 'facility': 'Diagnostic centre', 'geoPoint': {'lat': 51.50853, 'lon': -0.12574}}, {'zip': 'W1G 8BJ', 'city': 'London', 'status': 'RECRUITING', 'country': 'United Kingdom', 'facility': 'The Harley Street Clinic', 'geoPoint': {'lat': 51.50853, 'lon': -0.12574}}, {'zip': 'W1G 8PP', 'city': 'London', 'status': 'RECRUITING', 'country': 'United Kingdom', 'facility': 'Radiology', 'geoPoint': {'lat': 51.50853, 'lon': -0.12574}}], 'centralContacts': [{'name': 'Pfizer CT.gov Call Center', 'role': 'CONTACT', 'email': 'ClinicalTrials.gov_Inquiries@pfizer.com', 'phone': '1-800-718-1021'}], 'overallOfficials': [{'name': 'Pfizer CT.gov Call Center', 'role': 'STUDY_DIRECTOR', 'affiliation': 'Pfizer'}]}, 'ipdSharingStatementModule': {'ipdSharing': 'NO', 'description': "Pfizer will provide access to individual de-identified participant data and related study documents (e.g. protocol, Statistical Analysis Plan (SAP), Clinical Study Report (CSR)) upon request from qualified researchers, and subject to certain criteria, conditions, and exceptions. Further details on Pfizer's data sharing criteria and process for requesting access can be found at: https://www.pfizer.com/science/clinical\\_trials/trial\\_data\\_and\\_results/data\\_requests."}, 'sponsorCollaboratorsModule': {'leadSponsor': {'name': 'Seagen, a wholly owned subsidiary of Pfizer', 'class': 'INDUSTRY'}, 'responsibleParty': {'type': 'SPONSOR'}}}}