Ignite Creation Date:
2025-12-24 @ 1:10 PM
Ignite Modification Date:
2025-12-28 @ 12:27 AM
Study NCT ID:
NCT03811561
Status:
ACTIVE_NOT_RECRUITING
Last Update Posted:
2025-12-23
First Post:
2019-01-18
Is NOT Gene Therapy:
True
Has Adverse Events:
False
Brief Title:
A Research Study to Look at How Semaglutide Compared to Placebo Affects Diabetic Eye Disease in People With Type 2 Diabetes
Sponsor:
Organization:
Raw JSON
{'hasResults': False, 'derivedSection': {'miscInfoModule': {'versionHolder': '2025-12-24'}, 'conditionBrowseModule': {'meshes': [{'id': 'D003924', 'term': 'Diabetes Mellitus, Type 2'}], 'ancestors': [{'id': 'D003920', 'term': 'Diabetes Mellitus'}, {'id': 'D044882', 'term': 'Glucose Metabolism Disorders'}, {'id': 'D008659', 'term': 'Metabolic Diseases'}, {'id': 'D009750', 'term': 'Nutritional and Metabolic Diseases'}, {'id': 'D004700', 'term': 'Endocrine System Diseases'}]}, 'interventionBrowseModule': {'meshes': [{'id': 'C000591245', 'term': 'semaglutide'}]}}, 'protocolSection': {'designModule': {'phases': ['PHASE3'], 'studyType': 'INTERVENTIONAL', 'designInfo': {'allocation': 'RANDOMIZED', 'maskingInfo': {'masking': 'QUADRUPLE', 'whoMasked': ['PARTICIPANT', 'CARE_PROVIDER', 'INVESTIGATOR', 'OUTCOMES_ASSESSOR'], 'maskingDescription': 'Sponsor staff involved in the clinical trial is masked according to company standard procedures.'}, 'primaryPurpose': 'TREATMENT', 'interventionModel': 'PARALLEL'}, 'enrollmentInfo': {'type': 'ESTIMATED', 'count': 1500}}, 'statusModule': {'overallStatus': 'ACTIVE_NOT_RECRUITING', 'startDateStruct': {'date': '2019-05-08', 'type': 'ACTUAL'}, 'expandedAccessInfo': {'hasExpandedAccess': False}, 'statusVerifiedDate': '2025-12', 'completionDateStruct': {'date': '2027-11-07', 'type': 'ESTIMATED'}, 'lastUpdateSubmitDate': '2025-12-22', 'studyFirstSubmitDate': '2019-01-18', 'studyFirstSubmitQcDate': '2019-01-18', 'lastUpdatePostDateStruct': {'date': '2025-12-23', 'type': 'ESTIMATED'}, 'studyFirstPostDateStruct': {'date': '2019-01-22', 'type': 'ACTUAL'}, 'primaryCompletionDateStruct': {'date': '2026-12-25', 'type': 'ESTIMATED'}}, 'outcomesModule': {'primaryOutcomes': [{'measure': 'Presence of at least 3 steps Early Treatment Diabetic Retinopathy Study (ETDRS) subject level progression.', 'timeFrame': 'Year 5', 'description': 'Percentage of subjects (yes/no).'}], 'secondaryOutcomes': [{'measure': 'Time from randomisation to first at least 3 steps ETDRS subject level progression or central involved diabetic macular oedema (ciDME) in either eye.', 'timeFrame': 'Up to 5 years', 'description': 'Measured in months.'}, {'measure': 'Change in visual acuity in the worse seeing eye.', 'timeFrame': 'Week 0, Year 5', 'description': 'Measured in number of letters using the ETDRS protocol.'}, {'measure': 'Change in visual acuity in the better seeing eye.', 'timeFrame': 'Week 0, Year 5', 'description': 'Measured in number of letters using the ETDRS protocol.'}, {'measure': 'Occurrence of treatment for diabetic retinopathy or diabetic macular oedema in either eye with focal/grid laser photocoagulation.', 'timeFrame': 'Week 0-Year 5', 'description': 'Percentage of subjects (yes/no).'}, {'measure': 'Occurrence of treatment for diabetic retinopathy or diabetic macular oedema in either eye with pan-retinal laser photocoagulation.', 'timeFrame': 'Week 0-Year 5', 'description': 'Percentage of subjects (yes/no).'}, {'measure': 'Occurrence of treatment for diabetic retinopathy or diabetic macular oedema in either eye with intravitreal injection with anti-vascular endothelial growth factor (VEGF).', 'timeFrame': 'Week 0-Year 5', 'description': 'Percentage of subjects (yes/no).'}, {'measure': 'Occurrence of treatment for diabetic retinopathy or diabetic macular oedema in either eye with intravitreal injection with steroid.', 'timeFrame': 'Week 0-Year 5', 'description': 'Percentage of subjects (yes/no).'}, {'measure': 'Occurrence of treatment for diabetic retinopathy or diabetic macular oedema in either eye with vitrectomy.', 'timeFrame': 'Week 0-Year 5', 'description': 'Percentage of subjects (yes/no).'}, {'measure': 'Presence of at least 3 steps ETDRS subject level improvement.', 'timeFrame': 'Year 5', 'description': 'Percentage of subjects (yes/no).'}, {'measure': 'Presence of at least 2 steps ETDRS subject level progression.', 'timeFrame': 'Year 5', 'description': 'Percentage of subjects (yes/no).'}, {'measure': 'Presence of at least 2 steps ETDRS subject level improvement.', 'timeFrame': 'Year 5', 'description': 'Percentage of subjects (yes/no).'}, {'measure': 'Presence of persistent visual acuity up to 38 ETDRS letters in either eye.', 'timeFrame': 'Year 5', 'description': 'Percentage of subjects (yes/no).'}, {'measure': 'Presence of persistent at least 2 lines (10 letters) ETDRS worsening in visual acuity in either eye from baseline.', 'timeFrame': 'Year 5', 'description': 'Percentage of subjects (yes/no).'}, {'measure': 'Presence of persistent at least 3 lines (15 letters) ETDRS worsening in visual acuity in either eye from baseline.', 'timeFrame': 'Year 5', 'description': 'Percentage of subjects (yes/no).'}, {'measure': 'Presence of persistent at least 2 lines (10 letters) ETDRS improvement in visual acuity in either eye from baseline.', 'timeFrame': 'Year 5', 'description': 'Percentage of subjects (yes/no).'}, {'measure': 'Persistent at least 3 lines (15 letters) ETDRS improvement in visual acuity in either eye from baseline.', 'timeFrame': 'Year 5', 'description': 'Percentage of subjects (yes/no).'}, {'measure': 'Presence of ciDME in either eye.', 'timeFrame': 'Year 5', 'description': 'Percentage of subjects (yes/no).'}, {'measure': 'Change in glycosylated haemoglobin (HbA1c).', 'timeFrame': 'Week 0, Year 5', 'description': 'Measured in %-points.'}, {'measure': 'Change in body weight.', 'timeFrame': 'Week 0, Year 5', 'description': 'Measured in kg.'}, {'measure': 'Change in systolic and diastolic blood pressure.', 'timeFrame': 'Week 0, Year 5', 'description': 'Measured in mmHg.'}, {'measure': 'Change in Lipids: Total-cholesterol, High density lipoprotein (HDL)-cholesterol, low density lipoprotein (LDL)-cholesterol and triglycerides.', 'timeFrame': 'Week 0, Year 5', 'description': 'Measured in mmol/L'}]}, 'oversightModule': {'oversightHasDmc': True, 'isFdaRegulatedDrug': True, 'isFdaRegulatedDevice': False}, 'conditionsModule': {'conditions': ['Diabetes Mellitus, Type 2']}, 'descriptionModule': {'briefSummary': 'This study will look at the long-term effects of semaglutide (active medicine) on diabetic eye disease when compared to placebo (dummy medicine). The study will be performed in people with type 2 diabetes. Participants will either get semaglutide or placebo in addition to their diabetes medicines - which treatment the participant gets is decided by chance. Participants will inject the study medicine using a pen-injector. The medicine must be injected in a skin fold in the stomach, thigh or upper arm once a week. The study will last for 5 years.'}, 'eligibilityModule': {'sex': 'ALL', 'stdAges': ['ADULT', 'OLDER_ADULT'], 'minimumAge': '18 Years', 'healthyVolunteers': False, 'eligibilityCriteria': "Inclusion Criteria:\n\n* Male or female, age greater than or equal to 18 years at the time of signing informed consent\n* Diagnosed with type 2 diabetes mellitus.\n* HbA1c of 7.0-10.0% (53-86 mmol/mol) (both inclusive).\n* Eye inclusion criteria (both eyes must meet all criteria):\n* Early Treatment Diabetic Retinopathy Study (ETDRS) level of 10-75 (both inclusive) evaluated by fundus photography and confirmed by central reading centre\n* No ocular or intraocular treatment for diabetic retinopathy or diabetic macular oedema six months prior to the day of screening.\n* No anticipated need for ocular or intraocular treatment for diabetic retinopathy or diabetic macular oedema within three months after randomisation.\n* Best-corrected visual acuity greater than or equal to 30 letters using the ETDRS visual acuity protocol\n* No previous treatment with pan-retinal laser photocoagulation\n* No substantial non-diabetic ocular condition that, in the opinion of the ophthalmologist, would impact diabetic retinopathy or diabetic macular oedema progression during the trial\n* No substantial media opacities that would preclude successful imaging\n\nExclusion Criteria:\n\n* Any of the following: myocardial infarction, stroke, hospitalization for unstable angina pectoris or transient ischaemic attack within the past 60 days prior to the day of screening\n* Planned coronary, carotid or peripheral artery revascularisation known on the day of screening\n* Subjects presently classified as being in New York Heart Association (NYHA) Class IV\n* Renal impairment measured as estimated Glomerular Filtration Rate (eGFR) value of eGFR less than 30 ml/min/1.73 m\\^2\n* Personal or first degree relative(s) history of multiple endocrine neoplasia type 2 or medullary thyroid carcinoma\n* Presence or history of malignant neoplasms within the past 5 years prior to the day of screening. Basal and squamous cell skin cancer and any carcinoma in-situ are allowed\n* Female who is pregnant, breast-feeding or intends to become pregnant or is of child-bearing potential and not using highly effective contraceptive methods\n* Concurrent treatment with any GLP-1 receptor agonist or DPP-4 inhibitor from randomisation.\n* Receipt of any investigational medicinal product within 30 days before screening\n* Previous participation in this trial. Participation is defined as randomisation\n* Known or suspected hypersensitivity to trial products or related products\n* Any disorder, which in the investigator's opinion might jeopardise subject's safety or compliance with the protocol"}, 'identificationModule': {'nctId': 'NCT03811561', 'acronym': 'FOCUS', 'briefTitle': 'A Research Study to Look at How Semaglutide Compared to Placebo Affects Diabetic Eye Disease in People With Type 2 Diabetes', 'organization': {'class': 'INDUSTRY', 'fullName': 'Novo Nordisk A/S'}, 'officialTitle': 'Long-term Effects of Semaglutide on Diabetic Retinopathy in Subjects With Type 2 Diabetes', 'orgStudyIdInfo': {'id': 'NN9535-4352'}, 'secondaryIdInfos': [{'id': 'U1111-1201-6256', 'type': 'OTHER', 'domain': 'World Health Organization (WHO)'}, {'id': '2017-003619-20', 'type': 'REGISTRY', 'domain': 'European Medicines Agency (EudraCT)'}]}, 'armsInterventionsModule': {'armGroups': [{'type': 'EXPERIMENTAL', 'label': 'Semaglutide', 'description': 'Participants will receive semaglutide once weekly as subcutaneous (s.c., under the skin) injection added to standard of care.', 'interventionNames': ['Drug: Semaglutide']}, {'type': 'PLACEBO_COMPARATOR', 'label': 'Placebo', 'description': 'Participants will receive placebo (semaglutide) once weekly as subcutaneous subcutaneous (s.c., under the skin) injection added to standard of care.', 'interventionNames': ['Drug: Placebo (semaglutide)']}], 'interventions': [{'name': 'Semaglutide', 'type': 'DRUG', 'description': 'Participants will get one dose of semaglutide once weekly in addition to their diabetes medicines - which treatment they get is decided by chance. Participants will inject the study medicine using a pre-filled PDS290 pen-injector. The medicine must be injected in a skin fold in the stomach, thigh or upper arm once a week. Participants will start with once-weekly doses of 0.25 mg for 4 weeks, then the dose will be gradually increased to 0.5 mg once weekly for 4 weeks, and finally to 1.0 mg once weekly (maximum dose) up to 260 weeks (5 years).', 'armGroupLabels': ['Semaglutide']}, {'name': 'Placebo (semaglutide)', 'type': 'DRUG', 'description': 'Participants will get one dose of placebo (semaglutide) once weekly in addition to their diabetes medicines - which treatment they get is decided by chance. Participants will inject the study medicine using a pre-filled PDS290 pen-injector. The medicine must be injected in a skin fold in the stomach, thigh or upper arm once a week. Participants will start with once-weekly doses of 0.25 mg for 4 weeks, then the dose will be gradually increased to 0.5 mg once weekly for 4 weeks, and finally to 1.0 mg once weekly (maximum dose) up to 260 weeks (5 years).', 'armGroupLabels': ['Placebo']}]}, 'contactsLocationsModule': {'locations': [{'zip': '85050', 'city': 'Phoenix', 'state': 'Arizona', 'country': 'United States', 'facility': 'Synexus Rsch /Cnt Phnx Med C', 'geoPoint': {'lat': 33.44838, 'lon': -112.07404}}, {'zip': '85715', 'city': 'Tucson', 'state': 'Arizona', 'country': 'United States', 'facility': 'Del Sol Research Management, LLC', 'geoPoint': {'lat': 32.22174, 'lon': -110.92648}}, {'zip': '85723', 'city': 'Tucson', 'state': 'Arizona', 'country': 'United States', 'facility': 'South Arizona VA Healthcare System', 'geoPoint': {'lat': 32.22174, 'lon': -110.92648}}, {'zip': '85741', 'city': 'Tucson', 'state': 'Arizona', 'country': 'United States', 'facility': 'Synexus Cln Rsrch Inc - Orange Gro FP', 'geoPoint': {'lat': 32.22174, 'lon': -110.92648}}, {'zip': '92118', 'city': 'Coronado', 'state': 'California', 'country': 'United States', 'facility': 'Southern California Res Ctr', 'geoPoint': {'lat': 32.68589, 'lon': -117.18309}}, {'zip': '92627', 'city': 'Costa Mesa', 'state': 'California', 'country': 'United States', 'facility': 'FDRC', 'geoPoint': {'lat': 33.64113, 'lon': -117.91867}}, {'zip': '90250', 'city': 'Hawthorne', 'state': 'California', 'country': 'United States', 'facility': 'Advanced Investigative Medicine, Inc.', 'geoPoint': {'lat': 33.9164, 'lon': -118.35257}}, {'zip': '92648', 'city': 'Huntington Beach', 'state': 'California', 'country': 'United States', 'facility': 'Diabetes/Lipid Mgmt & Res Ctr', 'geoPoint': {'lat': 33.6603, 'lon': -117.99923}}, {'zip': '92037', 'city': 'La Jolla', 'state': 'California', 'country': 'United States', 'facility': 'Scripps Whittier Diabetes Inst', 'geoPoint': {'lat': 32.84727, 'lon': -117.2742}}, {'zip': '90717', 'city': 'Lomita', 'state': 'California', 'country': 'United States', 'facility': 'Torrance Clin Res Inst, Inc.', 'geoPoint': {'lat': 33.79224, 'lon': -118.31507}}, {'zip': '90010', 'city': 'Los Angeles', 'state': 'California', 'country': 'United States', 'facility': 'Angel City Research, Inc.', 'geoPoint': {'lat': 34.05223, 'lon': -118.24368}}, {'zip': '90017', 'city': 'Los Angeles', 'state': 'California', 'country': 'United States', 'facility': 'Downtown LA Res Ctr. Inc.', 'geoPoint': {'lat': 34.05223, 'lon': -118.24368}}, {'zip': '92555', 'city': 'Moreno Valley', 'state': 'California', 'country': 'United States', 'facility': 'Riverside University Health System Medical Center', 'geoPoint': {'lat': 33.93752, 'lon': -117.23059}}, {'zip': '91730-3063', 'city': 'Rancho Cucamonga', 'state': 'California', 'country': 'United States', 'facility': 'Rancho Cucamonga Clinical Research', 'geoPoint': {'lat': 34.1064, 'lon': -117.59311}}, {'zip': '95821', 'city': 'Sacramento', 'state': 'California', 'country': 'United States', 'facility': 'Clinical Trials Research_Sacramento_0', 'geoPoint': {'lat': 38.58157, 'lon': -121.4944}}, {'zip': '90404', 'city': 'Santa Monica', 'state': 'California', 'country': 'United States', 'facility': 'UCLA Diabetes Center at Santa Monica', 'geoPoint': {'lat': 34.01949, 'lon': -118.49138}}, {'zip': '93003', 'city': 'Ventura', 'state': 'California', 'country': 'United States', 'facility': 'Coastal Metabolic Research Center', 'geoPoint': {'lat': 34.27834, 'lon': -119.29317}}, {'zip': '94598', 'city': 'Walnut Creek', 'state': 'California', 'country': 'United States', 'facility': 'Diablo Clinical Research, Inc.', 'geoPoint': {'lat': 37.90631, 'lon': -122.06496}}, {'zip': '80045', 'city': 'Aurora', 'state': 'Colorado', 'country': 'United States', 'facility': 'Barbara Davis Center', 'geoPoint': {'lat': 39.72943, 'lon': -104.83192}}, {'zip': '80045', 'city': 'Aurora', 'state': 'Colorado', 'country': 'United States', 'facility': 'Rocky Mount Reg VA Med-DN', 'geoPoint': {'lat': 39.72943, 'lon': -104.83192}}, {'zip': '06708', 'city': 'Waterbury', 'state': 'Connecticut', 'country': 'United States', 'facility': 'Chase Medical Research LLC', 'geoPoint': {'lat': 41.55815, 'lon': -73.0515}}, {'zip': '33756', 'city': 'Clearwater', 'state': 'Florida', 'country': 'United States', 'facility': 'Innovative Research of W FL', 'geoPoint': {'lat': 27.96585, 'lon': -82.8001}}, {'zip': '32216', 'city': 'Jacksonville', 'state': 'Florida', 'country': 'United States', 'facility': 'Est Cst Inst for Rsrch,Jksnvil', 'geoPoint': {'lat': 30.33218, 'lon': -81.65565}}, {'zip': '33175', 'city': 'Miami', 'state': 'Florida', 'country': 'United States', 'facility': 'Reyes Clinical Research, Inc', 'geoPoint': {'lat': 25.77427, 'lon': -80.19366}}, {'zip': '34471', 'city': 'Ocala', 'state': 'Florida', 'country': 'United States', 'facility': 'Renstar Medical Research', 'geoPoint': {'lat': 29.1872, 'lon': -82.14009}}, {'zip': '30318', 'city': 'Atlanta', 'state': 'Georgia', 'country': 'United States', 'facility': 'Atlanta Diabetes Associates', 'geoPoint': {'lat': 33.749, 'lon': -84.38798}}, {'zip': '30076', 'city': 'Roswell', 'state': 'Georgia', 'country': 'United States', 'facility': 'Endo Res Solutions Inc', 'geoPoint': {'lat': 34.02316, 'lon': -84.36159}}, {'zip': '60607', 'city': 'Chicago', 'state': 'Illinois', 'country': 'United States', 'facility': 'Apex Medical Research Inc', 'geoPoint': {'lat': 41.85003, 'lon': -87.65005}}, {'zip': '60637', 'city': 'Chicago', 'state': 'Illinois', 'country': 'United States', 'facility': 'The University Of Chicago', 'geoPoint': {'lat': 41.85003, 'lon': -87.65005}}, {'zip': '46123', 'city': 'Avon', 'state': 'Indiana', 'country': 'United States', 'facility': 'American Health Network of Indiana, LLC_Avon', 'geoPoint': {'lat': 39.76282, 'lon': -86.39972}}, {'zip': '46140', 'city': 'Greenfield', 'state': 'Indiana', 'country': 'United States', 'facility': 'American Health Network of Indiana, LLC_Greenfield', 'geoPoint': {'lat': 39.78504, 'lon': -85.76942}}, {'zip': '50266', 'city': 'West Des Moines', 'state': 'Iowa', 'country': 'United States', 'facility': 'Iowa Diab & Endo Res Center', 'geoPoint': {'lat': 41.57721, 'lon': -93.71133}}, {'zip': '40502', 'city': 'Lexington', 'state': 'Kentucky', 'country': 'United States', 'facility': 'VA Medical Center', 'geoPoint': {'lat': 37.98869, 'lon': -84.47772}}, {'zip': '40503', 'city': 'Lexington', 'state': 'Kentucky', 'country': 'United States', 'facility': 'Kentucky Diabetes-Endocrinology Center', 'geoPoint': {'lat': 37.98869, 'lon': -84.47772}}, {'zip': '40503', 'city': 'Lexington', 'state': 'Kentucky', 'country': 'United States', 'facility': 'The Research Group of Lexington LLC', 'geoPoint': {'lat': 37.98869, 'lon': -84.47772}}, {'zip': '40213', 'city': 'Louisville', 'state': 'Kentucky', 'country': 'United States', 'facility': 'L-MARC Research Center', 'geoPoint': {'lat': 38.25424, 'lon': -85.75941}}, {'zip': '42001', 'city': 'Paducah', 'state': 'Kentucky', 'country': 'United States', 'facility': 'Four Rivers Clinical Research Inc', 'geoPoint': {'lat': 37.08339, 'lon': -88.60005}}, {'zip': '20782', 'city': 'Hyattsville', 'state': 'Maryland', 'country': 'United States', 'facility': 'MedStar Hlth Res Institute', 'geoPoint': {'lat': 38.95594, 'lon': -76.94553}}, {'zip': '02115', 'city': 'Boston', 'state': 'Massachusetts', 'country': 'United States', 'facility': "Brigham & Women's Hospital", 'geoPoint': {'lat': 42.35843, 'lon': -71.05977}}, {'zip': '02118', 'city': 'Boston', 'state': 'Massachusetts', 'country': 'United States', 'facility': 'Boston Medical Center_Cary', 'geoPoint': {'lat': 42.35843, 'lon': -71.05977}}, {'zip': '02215', 'city': 'Boston', 'state': 'Massachusetts', 'country': 'United States', 'facility': 'Joslin Center For Diabetes', 'geoPoint': {'lat': 42.35843, 'lon': -71.05977}}, {'zip': '02215', 'city': 'Boston', 'state': 'Massachusetts', 'country': 'United States', 'facility': 'Joslin Diabetes Center', 'geoPoint': {'lat': 42.35843, 'lon': -71.05977}}, {'zip': '48109', 'city': 'Ann Arbor', 'state': 'Michigan', 'country': 'United States', 'facility': 'Michigan Medicine', 'geoPoint': {'lat': 42.27756, 'lon': -83.74088}}, {'zip': '55432', 'city': 'Richfield', 'state': 'Minnesota', 'country': 'United States', 'facility': 'Synexus Clinical Research US, Inc._Tempe_0', 'geoPoint': {'lat': 44.8833, 'lon': -93.283}}, {'zip': '63017', 'city': 'Chesterfield', 'state': 'Missouri', 'country': 'United States', 'facility': 'Diabetes & Endo Specialists Inc', 'geoPoint': {'lat': 38.66311, 'lon': -90.57707}}, {'zip': '89148', 'city': 'Las Vegas', 'state': 'Nevada', 'country': 'United States', 'facility': 'Palm Research Center Inc-Vegas', 'geoPoint': {'lat': 36.17497, 'lon': -115.13722}}, {'zip': '03060', 'city': 'Nashua', 'state': 'New Hampshire', 'country': 'United States', 'facility': 'Southern New Hampshire Diabete', 'geoPoint': {'lat': 42.76537, 'lon': -71.46757}}, {'zip': '87108', 'city': 'Albuquerque', 'state': 'New Mexico', 'country': 'United States', 'facility': 'Lovelace Scientific Resources Inc', 'geoPoint': {'lat': 35.08449, 'lon': -106.65114}}, {'zip': '87131', 'city': 'Albuquerque', 'state': 'New Mexico', 'country': 'United States', 'facility': 'University of New Mexico', 'geoPoint': {'lat': 35.08449, 'lon': -106.65114}}, {'zip': '10016', 'city': 'New York', 'state': 'New York', 'country': 'United States', 'facility': 'NYC Research, Inc.', 'geoPoint': {'lat': 40.71427, 'lon': -74.00597}}, {'zip': '28803', 'city': 'Asheville', 'state': 'North Carolina', 'country': 'United States', 'facility': 'Mountain Diabetes & Endocrine Center', 'geoPoint': {'lat': 35.60095, 'lon': -82.55402}}, {'zip': '27514', 'city': 'Chapel Hill', 'state': 'North Carolina', 'country': 'United States', 'facility': 'University of North Carolina', 'geoPoint': {'lat': 35.9132, 'lon': -79.05584}}, {'zip': '28226', 'city': 'Charlotte', 'state': 'North Carolina', 'country': 'United States', 'facility': 'OnSite Clinical Solutions, LLC', 'geoPoint': {'lat': 35.22709, 'lon': -80.84313}}, {'zip': '44060', 'city': 'Mentor', 'state': 'Ohio', 'country': 'United States', 'facility': 'Your Diabetes Endocrine Nutrition Group, Inc.', 'geoPoint': {'lat': 41.66616, 'lon': -81.33955}}, {'zip': '43614', 'city': 'Toledo', 'state': 'Ohio', 'country': 'United States', 'facility': 'University of Toledo Medical Center', 'geoPoint': {'lat': 41.66394, 'lon': -83.55521}}, {'zip': '73104', 'city': 'Oklahoma City', 'state': 'Oklahoma', 'country': 'United States', 'facility': 'Harold Hamm Diabetes Center', 'geoPoint': {'lat': 35.46756, 'lon': -97.51643}}, {'zip': '19114', 'city': 'Philadelphia', 'state': 'Pennsylvania', 'country': 'United States', 'facility': 'Aria Endocrine Metabolic Assoc', 'geoPoint': {'lat': 39.95238, 'lon': -75.16362}}, {'zip': '19114', 'city': 'Philadelphia', 'state': 'Pennsylvania', 'country': 'United States', 'facility': 'Tristar Clin Investigations, PC', 'geoPoint': {'lat': 39.95238, 'lon': -75.16362}}, {'zip': '37620-7352', 'city': 'Bristol', 'state': 'Tennessee', 'country': 'United States', 'facility': 'Holston Medical Group Pc', 'geoPoint': {'lat': 36.59511, 'lon': -82.18874}}, {'zip': '37411', 'city': 'Chattanooga', 'state': 'Tennessee', 'country': 'United States', 'facility': 'Univ Diab & Endo Consultants', 'geoPoint': {'lat': 35.04563, 'lon': -85.30968}}, {'zip': '37660', 'city': 'Kingsport', 'state': 'Tennessee', 'country': 'United States', 'facility': 'Holston Medical Group', 'geoPoint': {'lat': 36.54843, 'lon': -82.56182}}, {'zip': '37212', 'city': 'Nashville', 'state': 'Tennessee', 'country': 'United States', 'facility': 'Vanderbilt Diab Obes Clin Tri', 'geoPoint': {'lat': 36.16589, 'lon': -86.78444}}, {'zip': '78705', 'city': 'Austin', 'state': 'Texas', 'country': 'United States', 'facility': 'Central Texas Clinical Research', 'geoPoint': {'lat': 30.26715, 'lon': -97.74306}}, {'zip': '78731', 'city': 'Austin', 'state': 'Texas', 'country': 'United States', 'facility': 'Texas Diab & Endo, P.A.', 'geoPoint': {'lat': 30.26715, 'lon': -97.74306}}, {'zip': '75230', 'city': 'Dallas', 'state': 'Texas', 'country': 'United States', 'facility': 'Velocity Clinical Res-Dallas', 'geoPoint': {'lat': 32.78306, 'lon': -96.80667}}, {'zip': '75390-9302', 'city': 'Dallas', 'state': 'Texas', 'country': 'United States', 'facility': 'UT Southwestern Med Cntr', 'geoPoint': {'lat': 32.78306, 'lon': -96.80667}}, {'zip': '78229', 'city': 'San Antonio', 'state': 'Texas', 'country': 'United States', 'facility': 'Clinical Trials of Texas, LLC', 'geoPoint': {'lat': 29.42412, 'lon': -98.49363}}, {'zip': '78230', 'city': 'San Antonio', 'state': 'Texas', 'country': 'United States', 'facility': 'VIP Trials', 'geoPoint': {'lat': 29.42412, 'lon': -98.49363}}, {'zip': '78231', 'city': 'Shavano Park', 'state': 'Texas', 'country': 'United States', 'facility': 'Consano Clinical Research, LLC', 'geoPoint': {'lat': 29.58495, 'lon': -98.55252}}, {'zip': '77478', 'city': 'Sugar Land', 'state': 'Texas', 'country': 'United States', 'facility': 'Simcare Medical Research, LLC', 'geoPoint': {'lat': 29.61968, 'lon': -95.63495}}, {'zip': '84107', 'city': 'Murray', 'state': 'Utah', 'country': 'United States', 'facility': 'Synexus Clinical Research US, INC.', 'geoPoint': {'lat': 40.66689, 'lon': -111.88799}}, {'zip': '99202', 'city': 'Spokane', 'state': 'Washington', 'country': 'United States', 'facility': 'MultiCare Inst for Res & Innov', 'geoPoint': {'lat': 47.65966, 'lon': -117.42908}}, {'zip': '01228-000', 'city': 'São Paulo', 'state': 'São Paulo', 'country': 'Brazil', 'facility': 'CPQuali Pesquisa Clínica Ltda', 'geoPoint': {'lat': -23.5475, 'lon': -46.63611}}, {'zip': '5801', 'city': 'Pleven', 'country': 'Bulgaria', 'facility': 'DCC I- Pleven EOOD Endocrinology', 'geoPoint': {'lat': 43.41791, 'lon': 24.61666}}, {'zip': '5806', 'city': 'Pleven', 'country': 'Bulgaria', 'facility': 'MHAT Sveti Pantaleimon - Pleven, Internal Diseases', 'geoPoint': {'lat': 43.41791, 'lon': 24.61666}}, {'zip': '4000', 'city': 'Plovdiv', 'country': 'Bulgaria', 'facility': 'MHAT Med Line Clinic', 'geoPoint': {'lat': 42.15387, 'lon': 24.75001}}, {'zip': '4002', 'city': 'Plovdiv', 'country': 'Bulgaria', 'facility': 'UMHAT Sveti Georgi EAD, Plovdiv, Clinic of Endocrinology', 'geoPoint': {'lat': 42.15387, 'lon': 24.75001}}, {'zip': '4003', 'city': 'Plovdiv', 'country': 'Bulgaria', 'facility': 'MHAT MC-Sv Ivan Rilski EOOD', 'geoPoint': {'lat': 42.15387, 'lon': 24.75001}}, {'zip': '1233', 'city': 'Sofia', 'country': 'Bulgaria', 'facility': '"DCC VII - Sofia", Endocrinology Consulting Room', 'geoPoint': {'lat': 42.69751, 'lon': 23.32415}}, {'zip': '1233', 'city': 'Sofia', 'country': 'Bulgaria', 'facility': 'DCC VII - Sofia EOOD, Endocrinology', 'geoPoint': {'lat': 42.69751, 'lon': 23.32415}}, {'zip': '1233', 'city': 'Sofia', 'country': 'Bulgaria', 'facility': 'MHAT Knyaginya Klementina - Sofia EAD', 'geoPoint': {'lat': 42.69751, 'lon': 23.32415}}, {'zip': '1431', 'city': 'Sofia', 'country': 'Bulgaria', 'facility': 'USHATE Akad. Ivan Penchev EAD, Second Clinic of Endocrinology', 'geoPoint': {'lat': 42.69751, 'lon': 23.32415}}, {'zip': '1606', 'city': 'Sofia', 'country': 'Bulgaria', 'facility': 'IV MHAT - Sofia EAD', 'geoPoint': {'lat': 42.69751, 'lon': 23.32415}}, {'zip': '1618', 'city': 'Sofia', 'country': 'Bulgaria', 'facility': '"DCC XX - Sofia" EOOD, Endocrinology Consulting Room', 'geoPoint': {'lat': 42.69751, 'lon': 23.32415}}, {'zip': '1680', 'city': 'Sofia', 'country': 'Bulgaria', 'facility': 'Medical centre Vitclinic EOOD', 'geoPoint': {'lat': 42.69751, 'lon': 23.32415}}, {'zip': 'T6G 2E1', 'city': 'Edmonton', 'state': 'Alberta', 'country': 'Canada', 'facility': 'Alberta Diabetes Institute', 'geoPoint': {'lat': 53.55014, 'lon': -113.46871}}, {'zip': 'L4K 4M2', 'city': 'Concord', 'state': 'Ontario', 'country': 'Canada', 'facility': 'LMC Clinical Res Thornhill', 'geoPoint': {'lat': 43.80011, 'lon': -79.48291}}, {'zip': 'M9R 4E1', 'city': 'Etobicoke', 'state': 'Ontario', 'country': 'Canada', 'facility': 'LMC Endo Ctr (Etobicoke) Ltd', 'geoPoint': {'lat': 43.64415, 'lon': -79.56985}}, {'zip': 'L6M 1M1', 'city': 'Oakville', 'state': 'Ontario', 'country': 'Canada', 'facility': 'LMC Oakville', 'geoPoint': {'lat': 43.45011, 'lon': -79.68292}}, {'zip': 'K1H7W9', 'city': 'Ottawa', 'state': 'Ontario', 'country': 'Canada', 'facility': 'The Ottawa Hospital_Riverside', 'geoPoint': {'lat': 45.41117, 'lon': -75.69812}}, {'zip': 'M4G 3E8', 'city': 'Toronto', 'state': 'Ontario', 'country': 'Canada', 'facility': 'LMC Endo Centres Ltd.(Bayview)', 'geoPoint': {'lat': 43.70643, 'lon': -79.39864}}, {'zip': 'H4A 2C6', 'city': 'Montreal', 'state': 'Quebec', 'country': 'Canada', 'facility': 'LMC Clinical Research, Inc. (Montreal Glen)', 'geoPoint': {'lat': 45.50884, 'lon': -73.58781}}, {'zip': 'H9R 4S3', 'city': 'Pointe-Claire', 'state': 'Quebec', 'country': 'Canada', 'facility': 'Centricity Res Pointe-Claire', 'geoPoint': {'lat': 45.44868, 'lon': -73.81669}}, {'zip': 'H4T 1Z9', 'city': 'Saint-Laurent', 'state': 'Quebec', 'country': 'Canada', 'facility': 'LMC Clin Rsrch Inc. (Montreal)', 'geoPoint': {'lat': 45.50008, 'lon': -73.66585}}, {'zip': '62500', 'city': 'Brno', 'country': 'Czechia', 'facility': 'Fakultni nemocnice Brno', 'geoPoint': {'lat': 49.19522, 'lon': 16.60796}}, {'zip': '500 05', 'city': 'Hradec Králové', 'country': 'Czechia', 'facility': 'Fakultni nemocnice Hradec Kralove', 'geoPoint': {'lat': 50.20923, 'lon': 15.83277}}, {'zip': '100 00', 'city': 'Prague', 'country': 'Czechia', 'facility': 'Diabetologie Krupska', 'geoPoint': {'lat': 50.08804, 'lon': 14.42076}}, {'zip': '100 34', 'city': 'Prague', 'country': 'Czechia', 'facility': 'Fakultni nemocnice Kralovske Vinohrady_Praha', 'geoPoint': {'lat': 50.08804, 'lon': 14.42076}}, {'zip': '140 00', 'city': 'Prague', 'country': 'Czechia', 'facility': 'Institut klinicke a experimentalni mediciny', 'geoPoint': {'lat': 50.08804, 'lon': 14.42076}}, {'zip': '140 00', 'city': 'Prague', 'country': 'Czechia', 'facility': 'MUDr. Michala Pelikanova', 'geoPoint': {'lat': 50.08804, 'lon': 14.42076}}, {'zip': '66299', 'city': 'Friedrichsthal', 'country': 'Germany', 'facility': 'Praxis Denger/Pfitzner, Friedrichsthal', 'geoPoint': {'lat': 49.32786, 'lon': 7.09622}}, {'zip': '21073', 'city': 'Hamburg', 'country': 'Germany', 'facility': 'Diabetologische Schwerpunktpraxis Harburg- Dr. med.Paschen,', 'geoPoint': {'lat': 53.55073, 'lon': 9.99302}}, {'zip': '21109', 'city': 'Hamburg', 'country': 'Germany', 'facility': 'Diabetes-Zentrum-Wilhelmsburg GbR', 'geoPoint': {'lat': 53.55073, 'lon': 9.99302}}, {'zip': '22607', 'city': 'Hamburg', 'country': 'Germany', 'facility': 'Wendisch/Dahl Hamburg (DZHW)', 'geoPoint': {'lat': 53.55073, 'lon': 9.99302}}, {'zip': '22607', 'city': 'Hamburg', 'country': 'Germany', 'facility': 'Wendisch/Dahl Hamburg', 'geoPoint': {'lat': 53.55073, 'lon': 9.99302}}, {'zip': '48145', 'city': 'Münster', 'country': 'Germany', 'facility': 'Institut für Diabetesforschung GmbH Münster - Dr. med. Rose', 'geoPoint': {'lat': 51.96236, 'lon': 7.62571}}, {'zip': '48153', 'city': 'Münster', 'country': 'Germany', 'facility': 'MedicalCenter am Clemenshospital - Schwerpunktpraxis für Diabetologie und Ernährungsmedizin', 'geoPoint': {'lat': 51.96236, 'lon': 7.62571}}, {'zip': '66780', 'city': 'Rehlingen-Siersburg', 'country': 'Germany', 'facility': 'Praxis Dr. med. Wenzl-Bauer', 'geoPoint': {'lat': 49.37565, 'lon': 6.68439}}, {'zip': '66386', 'city': 'Saint Ingbert-Oberwürzbach', 'country': 'Germany', 'facility': 'Zentrum für klinische Studien Alexander Segner'}, {'zip': '12462', 'city': 'Athens', 'state': 'Attica', 'country': 'Greece', 'facility': 'University Hospital of Athens ATTIKON', 'geoPoint': {'lat': 37.98376, 'lon': 23.72784}}, {'zip': '115 25', 'city': 'Athens', 'country': 'Greece', 'facility': 'Iatriko Psychicou Private Clinic', 'geoPoint': {'lat': 37.98376, 'lon': 23.72784}}, {'zip': '11527', 'city': 'Athens', 'country': 'Greece', 'facility': '"Laiko" General Hospital of Athens', 'geoPoint': {'lat': 37.98376, 'lon': 23.72784}}, {'zip': 'GR-11527', 'city': 'Athens', 'country': 'Greece', 'facility': '"Laiko" General Hospital of Athens', 'geoPoint': {'lat': 37.98376, 'lon': 23.72784}}, {'zip': 'GR-17562', 'city': 'Athens', 'country': 'Greece', 'facility': "Iatriko Athinon 'Palaiou Falirou'", 'geoPoint': {'lat': 37.98376, 'lon': 23.72784}}, {'zip': 'GR-12462', 'city': 'Haidari-Athens', 'country': 'Greece', 'facility': 'University Hospital of Athens ATTIKON'}, {'zip': '54642', 'city': 'Thessaloniki', 'country': 'Greece', 'facility': '"Ippokrateio" G.H. of Thessaloniki', 'geoPoint': {'lat': 40.64072, 'lon': 22.93493}}, {'zip': '57001', 'city': 'Thessaloniki', 'country': 'Greece', 'facility': '"Thermi" Private Hosital', 'geoPoint': {'lat': 40.64072, 'lon': 22.93493}}, {'zip': 'GR-57001', 'city': 'Thessaloniki', 'country': 'Greece', 'facility': '"Thermi" Private Hosital', 'geoPoint': {'lat': 40.64072, 'lon': 22.93493}}, {'zip': '522001', 'city': 'Guntur', 'state': 'Andhra Pradesh', 'country': 'India', 'facility': 'Endolife Specialty Hospitals', 'geoPoint': {'lat': 16.29974, 'lon': 80.45729}}, {'zip': '395002', 'city': 'Surat', 'state': 'Gujarat', 'country': 'India', 'facility': 'Nirmal Hospital Pvt. Ltd.', 'geoPoint': {'lat': 21.19594, 'lon': 72.83023}}, {'zip': '560 099', 'city': 'Bangalore', 'state': 'Karnataka', 'country': 'India', 'facility': 'Narayana Hrudayalya Institute of Cardiac Sciences', 'geoPoint': {'lat': 12.97194, 'lon': 77.59369}}, {'zip': '560010', 'city': 'Bangalore', 'state': 'Karnataka', 'country': 'India', 'facility': 'Diacon Hospital Private Limited', 'geoPoint': {'lat': 12.97194, 'lon': 77.59369}}, {'zip': '682041', 'city': 'Kochi', 'state': 'Kerala', 'country': 'India', 'facility': 'Amrita Institute Of Medical Sciences & Research Centre', 'geoPoint': {'lat': 9.93988, 'lon': 76.26022}}, {'zip': '695031', 'city': 'Thiruvananthapuram', 'state': 'Kerala', 'country': 'India', 'facility': 'Indian Institute of Diabetes', 'geoPoint': {'lat': 8.4855, 'lon': 76.94924}}, {'zip': '695033', 'city': 'Thiruvnanthapuram', 'state': 'Kerala', 'country': 'India', 'facility': 'Indian Institute of Diabetes'}, {'zip': '400008', 'city': 'Mumbai', 'state': 'Maharashtra', 'country': 'India', 'facility': 'BYL Nair Hospital and T N Medical College Department of endo', 'geoPoint': {'lat': 19.07283, 'lon': 72.88261}}, {'zip': '400012', 'city': 'Mumbai', 'state': 'Maharashtra', 'country': 'India', 'facility': 'Seth GS medical college and KEM Hospital', 'geoPoint': {'lat': 19.07283, 'lon': 72.88261}}, {'zip': '440009', 'city': 'Nagpur', 'state': 'Maharashtra', 'country': 'India', 'facility': 'Government Medical College and Super Speciality Hospital, Nagpur', 'geoPoint': {'lat': 21.14631, 'lon': 79.08491}}, {'zip': '440015', 'city': 'Nagpur', 'state': 'Maharashtra', 'country': 'India', 'facility': 'DEW Medicare & Trinity hospital', 'geoPoint': {'lat': 21.14631, 'lon': 79.08491}}, {'zip': '411004', 'city': 'Pune', 'state': 'Maharashtra', 'country': 'India', 'facility': 'Deenanath Mangeshkar Hospital & Research Centre', 'geoPoint': {'lat': 18.51957, 'lon': 73.85535}}, {'zip': '110029', 'city': 'Ansari Nagar, New Delhi 110029', 'state': 'New Delhi', 'country': 'India', 'facility': 'All India Institute of Medical Sciences'}, {'zip': '110076', 'city': 'Delhi', 'state': 'New Delhi', 'country': 'India', 'facility': 'Apollo Hospital', 'geoPoint': {'lat': 28.65195, 'lon': 77.23149}}, {'zip': '110076', 'city': 'Delhi', 'state': 'New Delhi', 'country': 'India', 'facility': 'Indraprastha Apollo Hospital', 'geoPoint': {'lat': 28.65195, 'lon': 77.23149}}, {'zip': '110029', 'city': 'New Dehli', 'state': 'New Delhi', 'country': 'India', 'facility': 'All India Institute of Medical Sciences'}, {'zip': '141001', 'city': 'Ludhiana', 'state': 'Punjab', 'country': 'India', 'facility': 'Dayanand Medical College & Hospital_Ludhiana', 'geoPoint': {'lat': 30.91204, 'lon': 75.85379}}, {'zip': '141008', 'city': 'Ludhiana', 'state': 'Punjab', 'country': 'India', 'facility': 'Christian Medical College and Hospital', 'geoPoint': {'lat': 30.91204, 'lon': 75.85379}}, {'zip': '600086', 'city': 'Chennai', 'state': 'Tamil Nadu', 'country': 'India', 'facility': 'Madras Diabetes Research Foundation', 'geoPoint': {'lat': 13.08784, 'lon': 80.27847}}, {'zip': '625 020', 'city': 'Madurai', 'state': 'Tamil Nadu', 'country': 'India', 'facility': 'Arthur Asirvatham hospital,', 'geoPoint': {'lat': 9.919, 'lon': 78.11953}}, {'zip': '700020', 'city': 'Kolkata', 'state': 'West Bengal', 'country': 'India', 'facility': 'SSKM', 'geoPoint': {'lat': 22.56263, 'lon': 88.36304}}, {'zip': '700054', 'city': 'Kolkata', 'state': 'West Bengal', 'country': 'India', 'facility': 'Apollo Gleneagles Hospital', 'geoPoint': {'lat': 22.56263, 'lon': 88.36304}}, {'zip': '700054', 'city': 'Kolkata', 'state': 'West Bengal', 'country': 'India', 'facility': 'Apollo Multispeciality Hospital, Kolkata', 'geoPoint': {'lat': 22.56263, 'lon': 88.36304}}, {'zip': '600034', 'city': 'Hyderabad', 'country': 'India', 'facility': 'Care Hospital', 'geoPoint': {'lat': 17.38405, 'lon': 78.45636}}, {'zip': '400031', 'city': 'Mumbai', 'country': 'India', 'facility': 'Aditya Jyot Hospital', 'geoPoint': {'lat': 19.07283, 'lon': 72.88261}}, {'zip': '31096', 'city': 'Haifa', 'country': 'Israel', 'facility': 'Rambam MC - Diabetes and obesity center of excellence', 'geoPoint': {'lat': 32.81303, 'lon': 34.99928}}, {'zip': '91120', 'city': 'Jerusalem', 'country': 'Israel', 'facility': 'Hadassah Ein Karam MC - Diabetes Unit', 'geoPoint': {'lat': 31.76904, 'lon': 35.21633}}, {'zip': '44281', 'city': 'Kfar Saba', 'country': 'Israel', 'facility': 'Meir MC - Diabetes unit', 'geoPoint': {'lat': 32.175, 'lon': 34.90694}}, {'zip': '49100', 'city': 'Petah Tikva', 'country': 'Israel', 'facility': 'Rabin MC Beilinson - Endo unit', 'geoPoint': {'lat': 32.08707, 'lon': 34.88747}}, {'zip': '64239', 'city': 'Tel Aviv', 'country': 'Israel', 'facility': 'Sourasky MC - Institute of Endocrinology, metabolism and hypertension', 'geoPoint': {'lat': 32.08088, 'lon': 34.78057}}, {'zip': '52621', 'city': 'Tel Litwinsky', 'country': 'Israel', 'facility': 'Sheba MC - Endocrinology Clinic', 'geoPoint': {'lat': 32.05096, 'lon': 34.84588}}, {'zip': '3001', 'city': 'Jelgava', 'country': 'Latvia', 'facility': 'Zemgales diabetes centre', 'geoPoint': {'lat': 56.65, 'lon': 23.71278}}, {'zip': '5001', 'city': 'Ogre', 'country': 'Latvia', 'facility': 'Teterovska practice', 'geoPoint': {'lat': 56.8162, 'lon': 24.61401}}, {'zip': '1002', 'city': 'Riga', 'country': 'Latvia', 'facility': 'P. Stradins Clinical University Hospital', 'geoPoint': {'lat': 56.946, 'lon': 24.10589}}, {'zip': '1011', 'city': 'Riga', 'country': 'Latvia', 'facility': 'Medical Centre Pulss 5', 'geoPoint': {'lat': 56.946, 'lon': 24.10589}}, {'zip': 'LV-1024', 'city': 'Riga', 'country': 'Latvia', 'facility': 'Juglas Medicine Center', 'geoPoint': {'lat': 56.946, 'lon': 24.10589}}, {'zip': '14080', 'city': 'Distrito Federal', 'state': 'México, D.F.', 'country': 'Mexico', 'facility': 'Instituto Nacional de Nutricion - Unidad de Inv de Enf Metab', 'geoPoint': {'lat': 16.59, 'lon': -93.02694}}, {'zip': '64460', 'city': 'Monterrey', 'state': 'Nuevo León', 'country': 'Mexico', 'facility': 'Hospital Universitario Dr. José Eleuterio González_Monterrey', 'geoPoint': {'lat': 25.68435, 'lon': -100.31721}}, {'zip': '15-276', 'city': 'Bialystok', 'state': 'Podlaskie Voivodeship', 'country': 'Poland', 'facility': 'Uniwersytecki Szpital Kliniczny w Bialymstoku', 'geoPoint': {'lat': 53.13333, 'lon': 23.16433}}, {'zip': '85-048', 'city': 'Bydgoszcz', 'country': 'Poland', 'facility': 'In-Vivo Sp. z o.o.', 'geoPoint': {'lat': 53.1235, 'lon': 18.00762}}, {'zip': '41-500', 'city': 'Chorzów', 'country': 'Poland', 'facility': 'B_Serwis Popenda Sp.J.', 'geoPoint': {'lat': 50.30582, 'lon': 18.9742}}, {'zip': '80-382', 'city': 'Gdansk', 'country': 'Poland', 'facility': 'Synexus Polska Sp. z o.o. Oddzial w Gdansku', 'geoPoint': {'lat': 54.35227, 'lon': 18.64912}}, {'zip': '80-858', 'city': 'Gdansk', 'country': 'Poland', 'facility': 'NZOZ Gdanska Poradnia Cukrzycowa Sp.z o.o.', 'geoPoint': {'lat': 54.35227, 'lon': 18.64912}}, {'zip': '40-081', 'city': 'Katowice', 'country': 'Poland', 'facility': 'Centrum Medyczne Pratia Katowice', 'geoPoint': {'lat': 50.2597, 'lon': 19.02173}}, {'zip': '40-156', 'city': 'Katowice', 'country': 'Poland', 'facility': 'Clinical Medical Research Korfantego - Ambulatoryjna Opieka', 'geoPoint': {'lat': 50.2597, 'lon': 19.02173}}, {'zip': '31-501', 'city': 'Krakow', 'country': 'Poland', 'facility': 'FutureMeds Sp. z o.o.', 'geoPoint': {'lat': 50.06143, 'lon': 19.93658}}, {'zip': '90-302', 'city': 'Lodz', 'country': 'Poland', 'facility': 'Santa Sp. z o.o, Santa Familia Centrum Badan, Profilaktyki i Leczenia', 'geoPoint': {'lat': 51.77058, 'lon': 19.47395}}, {'zip': '90-338', 'city': 'Lodz', 'country': 'Poland', 'facility': 'Centrum Terapii Wspolczesnej J.M. Jasnorzewska S.K.A.', 'geoPoint': {'lat': 51.77058, 'lon': 19.47395}}, {'zip': '94-047', 'city': 'Lodz', 'country': 'Poland', 'facility': 'Prywatny Gabinet Lekarski Jan Ruxer', 'geoPoint': {'lat': 51.77058, 'lon': 19.47395}}, {'zip': '60-821', 'city': 'Poznan', 'country': 'Poland', 'facility': 'NZOZ "DiabMed" Poradnia Diabetologiczna', 'geoPoint': {'lat': 52.40692, 'lon': 16.92993}}, {'zip': '61-251', 'city': 'Poznan', 'country': 'Poland', 'facility': 'Gaja Poradnie Lekarskie', 'geoPoint': {'lat': 52.40692, 'lon': 16.92993}}, {'zip': '09-100', 'city': 'Płońsk', 'country': 'Poland', 'facility': 'SPZZOZ im. Marszalka J. Pilsudskiego w Plonsku', 'geoPoint': {'lat': 52.62348, 'lon': 20.37552}}, {'zip': '41-800', 'city': 'Zabrze', 'country': 'Poland', 'facility': 'SPSK nr 1 im. prof. Stanisława Szyszko Śląskiego Uniwersytetu Medycznego w Katowicach, ul. 3-go Maja 13/15 41-800 Zabrze', 'geoPoint': {'lat': 50.32492, 'lon': 18.78576}}, {'zip': '90-302', 'city': 'Lodz', 'state': 'Łódź Voivodeship', 'country': 'Poland', 'facility': 'Santa Sp. z o.o, Santa Familia Centrum Badan, Profilaktyki i Leczenia', 'geoPoint': {'lat': 51.77058, 'lon': 19.47395}}, {'zip': '4464-513', 'city': 'Senhora Da Hora, Matosinhos', 'state': 'Matosinhos', 'country': 'Portugal', 'facility': 'ULS De Matosinhos E.P.E.- Hospital Pedro Hispano'}, {'zip': '2805-267', 'city': 'Almada', 'country': 'Portugal', 'facility': 'ULS Almada-Seixal E.P.E. - Hospital Garcia de Orta', 'geoPoint': {'lat': 38.67902, 'lon': -9.1569}}, {'zip': '3814-501', 'city': 'Aveiro', 'country': 'Portugal', 'facility': 'ULS Da Regiao De Aveiro E.P.E. - Hospital Infante D. Pedro', 'geoPoint': {'lat': 40.64575, 'lon': -8.64643}}, {'zip': '3000-561', 'city': 'Coimbra', 'country': 'Portugal', 'facility': 'Unidade Local de Saúde de Coimbra, E.P.E.', 'geoPoint': {'lat': 40.20686, 'lon': -8.41996}}, {'zip': '4835-044', 'city': 'Guimarães', 'country': 'Portugal', 'facility': 'ULS Do Alto Ave, E.P.E. - Hospital Senhora da Oliveira - Guimarães', 'geoPoint': {'lat': 41.44443, 'lon': -8.29619}}, {'zip': '1250-230', 'city': 'Lisbon', 'country': 'Portugal', 'facility': 'APDP - Associação Protectora dos Diabéticos de Portugal', 'geoPoint': {'lat': 38.72509, 'lon': -9.1498}}, {'zip': '4200-319', 'city': 'Porto', 'country': 'Portugal', 'facility': 'Centro Hospitalar de São João', 'geoPoint': {'lat': 41.1485, 'lon': -8.61097}}, {'zip': '4200-319', 'city': 'Porto', 'country': 'Portugal', 'facility': 'Unidade Local de Saude de Sao Joao E.P.E', 'geoPoint': {'lat': 41.1485, 'lon': -8.61097}}, {'zip': '2910-446', 'city': 'Setúbal', 'country': 'Portugal', 'facility': 'ULS Da Arrábida, E.P.E._Hospital de São Bernardo', 'geoPoint': {'lat': 38.5244, 'lon': -8.8882}}, {'zip': '020475', 'city': 'Bucharest', 'state': 'Bucurestii', 'country': 'Romania', 'facility': 'Institutul National De Diabet Nutritie Si Boli Metabolice Prof.Dr.N.Paulescu Bucuresti- Ion Movila', 'geoPoint': {'lat': 44.43225, 'lon': 26.10626}}, {'zip': '400006', 'city': 'Cluj-Napoca', 'state': 'Cluj', 'country': 'Romania', 'facility': 'Clinic of Diabetes Cluj', 'geoPoint': {'lat': 46.76667, 'lon': 23.6}}, {'zip': '300456', 'city': 'Timișoara', 'state': 'Timiș County', 'country': 'Romania', 'facility': 'SC Centru Medical Dr. Negrisanu SRL', 'geoPoint': {'lat': 45.75372, 'lon': 21.22571}}, {'zip': '300736', 'city': 'Timișoara', 'state': 'Timiș County', 'country': 'Romania', 'facility': '3rd Clinic for Nutrition-Spitalulul Județean de Urgenta', 'geoPoint': {'lat': 45.75372, 'lon': 21.22571}}, {'zip': '010825', 'city': 'Bucharest', 'country': 'Romania', 'facility': '"Carol Davila" Military Emergency Hospital', 'geoPoint': {'lat': 44.43225, 'lon': 26.10626}}, {'zip': '011025', 'city': 'Bucharest', 'country': 'Romania', 'facility': 'Sana Monitoring SRL', 'geoPoint': {'lat': 44.43225, 'lon': 26.10626}}, {'zip': '020359', 'city': 'Bucharest', 'country': 'Romania', 'facility': 'SC Clinica Diabnutrimed S.R.L.', 'geoPoint': {'lat': 44.43225, 'lon': 26.10626}}, {'zip': '656043', 'city': 'Barnaul', 'country': 'Russia', 'facility': 'Multispecialty Medical Clinic Anturium LLC', 'geoPoint': {'lat': 53.36199, 'lon': 83.72786}}, {'zip': '420012', 'city': "Kazan'", 'country': 'Russia', 'facility': 'Kazan Federal University', 'geoPoint': {'lat': 55.78874, 'lon': 49.12214}}, {'zip': '420061', 'city': "Kazan'", 'country': 'Russia', 'facility': 'PIH "Clin Hosp "RZD-Medicina" former Kazan OJSC Rus Railways', 'geoPoint': {'lat': 55.78874, 'lon': 49.12214}}, {'zip': '420097', 'city': "Kazan'", 'country': 'Russia', 'facility': 'Kazan Federal University', 'geoPoint': {'lat': 55.78874, 'lon': 49.12214}}, {'zip': '117292', 'city': 'Moscow', 'country': 'Russia', 'facility': "FSBI 'I.I. Dedov National Medical Research Center of Endocrinology' of the MH of Russia", 'geoPoint': {'lat': 55.75204, 'lon': 37.61781}}, {'zip': '117292', 'city': 'Moscow', 'country': 'Russia', 'facility': 'National Medical Research Center of Endocrinology', 'geoPoint': {'lat': 55.75204, 'lon': 37.61781}}, {'zip': '143026', 'city': 'Moscow', 'country': 'Russia', 'facility': 'Branch of limited liability company "Hadassah Medical LTD"', 'geoPoint': {'lat': 55.75204, 'lon': 37.61781}}, {'zip': '630087', 'city': 'Novosibirsk', 'country': 'Russia', 'facility': 'State Novosibirsk regional clinical hospital', 'geoPoint': {'lat': 55.02259, 'lon': 82.93175}}, {'zip': '194354', 'city': 'Saint Petersburg', 'country': 'Russia', 'facility': 'City Consultative & Diagnostic Centre #1', 'geoPoint': {'lat': 59.93863, 'lon': 30.31413}}, {'zip': '196084', 'city': 'Saint Petersburg', 'country': 'Russia', 'facility': 'Diagnistic Centre "Energo"', 'geoPoint': {'lat': 59.93863, 'lon': 30.31413}}, {'zip': '197110', 'city': 'Saint Petersburg', 'country': 'Russia', 'facility': 'Consultative & Diagnostic Center with a Outpatient Hospital', 'geoPoint': {'lat': 59.93863, 'lon': 30.31413}}, {'zip': '194044', 'city': 'Saint-Peterburg', 'country': 'Russia', 'facility': 'Llc "International Medical Center "Time"'}, {'zip': '410031', 'city': 'Saratov', 'country': 'Russia', 'facility': 'SHI Saratov City Clinical Hospital #9', 'geoPoint': {'lat': 51.54048, 'lon': 45.9901}}, {'zip': '410039', 'city': 'Saratov', 'country': 'Russia', 'facility': 'Regional clinical cardiology dispensary', 'geoPoint': {'lat': 51.54048, 'lon': 45.9901}}, {'zip': '620102', 'city': 'Yekaterinburg', 'country': 'Russia', 'facility': 'Sverdlovsk Regional Clinical Hospital #1', 'geoPoint': {'lat': 56.85733, 'lon': 60.61529}}, {'zip': '21000', 'city': 'Novi Sad', 'state': 'Vojvodina', 'country': 'Serbia', 'facility': 'Clin. Centre Vojvodina, Clin. endocr., diab. and met. dis.', 'geoPoint': {'lat': 45.25167, 'lon': 19.83694}}, {'zip': '11000', 'city': 'Belgrade', 'country': 'Serbia', 'facility': 'CHC Zvezdara, Clinical department for endocrinology', 'geoPoint': {'lat': 44.80401, 'lon': 20.46513}}, {'zip': '11000', 'city': 'Belgrade', 'country': 'Serbia', 'facility': 'Endocrinology, Diabetes and Metabolism Diseases Clinic', 'geoPoint': {'lat': 44.80401, 'lon': 20.46513}}, {'zip': '11080', 'city': 'Belgrade', 'country': 'Serbia', 'facility': 'Clinical Hospital Center Bezanijska Kosa', 'geoPoint': {'lat': 44.80401, 'lon': 20.46513}}, {'zip': '18000', 'city': 'Niš', 'country': 'Serbia', 'facility': 'Clinical Centre Nis, Endocrinology, Diabetes and Metabolism', 'geoPoint': {'lat': 43.32472, 'lon': 21.90333}}, {'zip': '82606', 'city': 'Bratislava', 'country': 'Slovakia', 'facility': 'V. interna klinika LF UK a UNB', 'geoPoint': {'lat': 48.14816, 'lon': 17.10674}}, {'zip': '833 05', 'city': 'Bratislava', 'country': 'Slovakia', 'facility': 'Nemocnica akademika L. Derera, UNB', 'geoPoint': {'lat': 48.14816, 'lon': 17.10674}}, {'zip': '01001', 'city': 'Žilina', 'country': 'Slovakia', 'facility': 'Diabetologicka ambulancia, Dia Zilina s.r.o.', 'geoPoint': {'lat': 49.22315, 'lon': 18.73941}}, {'zip': '01001', 'city': 'Žilina', 'country': 'Slovakia', 'facility': 'Medivasa s.r.o., Diabetologicka ambulancia', 'geoPoint': {'lat': 49.22315, 'lon': 18.73941}}, {'zip': '01001', 'city': 'Žilina', 'country': 'Slovakia', 'facility': 'MEDIVASA, s.r.o., Diabetologicka ambulancia', 'geoPoint': {'lat': 49.22315, 'lon': 18.73941}}, {'zip': '15006', 'city': 'A Coruña', 'country': 'Spain', 'facility': 'Complejo Hospitalario Universitario A Coruña', 'geoPoint': {'lat': 43.37135, 'lon': -8.396}}, {'zip': '08035', 'city': 'Barcelona', 'country': 'Spain', 'facility': "Hospital Vall d'Hebron", 'geoPoint': {'lat': 41.38879, 'lon': 2.15899}}, {'zip': '08907', 'city': "L'Hospitalet de Llobregat", 'country': 'Spain', 'facility': 'Hospital de Bellvitge', 'geoPoint': {'lat': 41.35967, 'lon': 2.10028}}, {'zip': '31008', 'city': 'Pamplona', 'country': 'Spain', 'facility': 'Clinica Universitaria de Navarra', 'geoPoint': {'lat': 42.81687, 'lon': -1.64323}}, {'zip': '41009', 'city': 'Seville', 'country': 'Spain', 'facility': 'Hospital Virgen de la Macarena', 'geoPoint': {'lat': 37.38283, 'lon': -5.97317}}, {'zip': '46026', 'city': 'Valencia', 'country': 'Spain', 'facility': 'Hospital La Fe - Endocrinología y Nutrición', 'geoPoint': {'lat': 39.47391, 'lon': -0.37966}}, {'zip': 'HG2 7SX', 'city': 'Harrogate', 'state': 'North Yorkshire', 'country': 'United Kingdom', 'facility': 'Harrogate District Hospital', 'geoPoint': {'lat': 53.99078, 'lon': -1.5373}}, {'zip': 'NG7 2UH', 'city': 'Nottingham', 'state': 'Nottinghamshire', 'country': 'United Kingdom', 'facility': "Queen's Medical Centre University Hospital", 'geoPoint': {'lat': 52.9536, 'lon': -1.15047}}, {'zip': 'NG7 2UH', 'city': 'Nottingham', 'state': 'Nottinghamshire', 'country': 'United Kingdom', 'facility': 'University Hospital, Queens Medical Centre', 'geoPoint': {'lat': 52.9536, 'lon': -1.15047}}, {'zip': 'BA21 4AT', 'city': 'Yeovil', 'state': 'Somerset', 'country': 'United Kingdom', 'facility': 'Yeovil District Hospital - Clinical Research Unit', 'geoPoint': {'lat': 50.94159, 'lon': -2.63211}}, {'zip': 'SE5 9RS', 'city': 'London', 'country': 'United Kingdom', 'facility': 'Kings College Hospital', 'geoPoint': {'lat': 51.50853, 'lon': -0.12574}}, {'zip': 'NR4 7UQ', 'city': 'Norfolk', 'country': 'United Kingdom', 'facility': 'Norfolk and Norwich University Hospital'}, {'zip': 'CV10 7DJ', 'city': 'Nuneaton', 'country': 'United Kingdom', 'facility': 'George Eliot Hospital NHS Trust', 'geoPoint': {'lat': 52.52323, 'lon': -1.46523}}, {'zip': 'CV10 7DJ', 'city': 'Nuneaton', 'country': 'United Kingdom', 'facility': 'George Eliot Hospital', 'geoPoint': {'lat': 52.52323, 'lon': -1.46523}}, {'zip': 'BA21 4AT', 'city': 'Somerset', 'country': 'United Kingdom', 'facility': 'Clinical Research Unit'}, {'zip': 'TR1 3LJ', 'city': 'Truro', 'country': 'United Kingdom', 'facility': 'Royal Cornwall Hospital (Treliske)', 'geoPoint': {'lat': 50.26526, 'lon': -5.05436}}], 'overallOfficials': [{'name': 'Clinical Reporting Anchor and Disclosure (1452)', 'role': 'STUDY_DIRECTOR', 'affiliation': 'Novo Nordisk A/S'}]}, 'ipdSharingStatementModule': {'url': 'http://novonordisk-trials.com', 'ipdSharing': 'YES', 'description': 'According to the Novo Nordisk disclosure commitment on novonordisk-trials.com'}, 'sponsorCollaboratorsModule': {'leadSponsor': {'name': 'Novo Nordisk A/S', 'class': 'INDUSTRY'}, 'responsibleParty': {'type': 'SPONSOR'}}}}