Ignite Creation Date:
2025-12-24 @ 9:19 PM
Ignite Modification Date:
2025-12-29 @ 9:53 PM
Study NCT ID:
NCT01262404
Status:
UNKNOWN
Last Update Posted:
2010-12-17
First Post:
2010-12-16
Is NOT Gene Therapy:
True
Has Adverse Events:
False
Brief Title:
Imaging Cerebral and Sub-cerebral Correlates of Meditative States
Sponsor:
Organization:
Raw JSON
{'hasResults': False, 'derivedSection': {'miscInfoModule': {'versionHolder': '2025-12-24'}}, 'protocolSection': {'designModule': {'studyType': 'OBSERVATIONAL', 'designInfo': {'timePerspective': 'CROSS_SECTIONAL', 'observationalModel': 'COHORT'}, 'enrollmentInfo': {'type': 'ESTIMATED', 'count': 58}}, 'statusModule': {'overallStatus': 'UNKNOWN', 'lastKnownStatus': 'RECRUITING', 'startDateStruct': {'date': '2010-01'}, 'expandedAccessInfo': {'hasExpandedAccess': False}, 'statusVerifiedDate': '2010-12', 'completionDateStruct': {'date': '2011-10', 'type': 'ESTIMATED'}, 'lastUpdateSubmitDate': '2010-12-16', 'studyFirstSubmitDate': '2010-12-16', 'studyFirstSubmitQcDate': '2010-12-16', 'lastUpdatePostDateStruct': {'date': '2010-12-17', 'type': 'ESTIMATED'}, 'studyFirstPostDateStruct': {'date': '2010-12-17', 'type': 'ESTIMATED'}, 'primaryCompletionDateStruct': {'date': '2011-10', 'type': 'ESTIMATED'}}, 'oversightModule': {'oversightHasDmc': True}, 'conditionsModule': {'conditions': ['Stress']}, 'descriptionModule': {'briefSummary': 'Three groups of subjects are trained to practice mindfulness meditation, compassion meditation, or attend a health training control class. Individuals from each group will undergo structural and functional brain imaging before and after training. The hypothesis is that the compassion meditation group will show the largest changes in brain structure and function. In a second series of experiments, the subjects practicing a Tibetan meditation practice will be undergo MRI thermometry imaging to construct detailed three dimensional temperature maps of their bodies before, during, and after they perform this practice.', 'detailedDescription': 'Structural (MRI) Imaging will be used to measure changes in cortical thickness in the pre and post training groups. Function (fMRI) Imaging will be used to measure changes in cortical and sub-cortical responses to a series of affectively controlled visual images, presented during scanning. MRI Thermometry Imaging will be used to construct three dimensional temperature maps of subjects while performing meditation in the scanner.'}, 'eligibilityModule': {'sex': 'ALL', 'stdAges': ['ADULT', 'OLDER_ADULT'], 'maximumAge': '65 Years', 'minimumAge': '18 Years', 'samplingMethod': 'NON_PROBABILITY_SAMPLE', 'studyPopulation': 'Community Sample', 'healthyVolunteers': True, 'eligibilityCriteria': 'Inclusion Criteria:\n\n* Age 18-65 for the mindfulness-compassion study\n* Prior training in gtummo meditation for the gtummo study\n\nExclusion Criteria:\n\n* Previous experience with meditation for the mindfulness-compassion study'}, 'identificationModule': {'nctId': 'NCT01262404', 'acronym': 'calm', 'briefTitle': 'Imaging Cerebral and Sub-cerebral Correlates of Meditative States', 'organization': {'class': 'OTHER', 'fullName': 'Boston University'}, 'officialTitle': 'Imaging Cerebral and Sub-cerebral Correlates of Meditative States', 'orgStudyIdInfo': {'id': 'BU-Emory-01'}, 'secondaryIdInfos': [{'id': 'AT005728-01', 'type': 'OTHER_GRANT', 'domain': 'NCCAM'}]}, 'armsInterventionsModule': {'armGroups': [{'label': 'HealthEd,Minfdulness,Compassion', 'description': 'HealthEd receives training health education. Mindfulness receives training in mindfulness meditation. Compassion receives training in compassion meditation.'}]}, 'contactsLocationsModule': {'locations': [{'zip': '02215', 'city': 'Boston', 'state': 'Massachusetts', 'status': 'RECRUITING', 'country': 'United States', 'contacts': [{'name': 'Eric L Schwartz, PhD', 'role': 'PRINCIPAL_INVESTIGATOR'}], 'facility': 'Boston University Dept. of Cognitive and Neural Systems', 'geoPoint': {'lat': 42.35843, 'lon': -71.05977}}], 'centralContacts': [{'name': 'Terri Sivilli, AB', 'role': 'CONTACT', 'email': 'tsivil@emory.edu', 'phone': '404 778 2256'}], 'overallOfficials': [{'name': 'Eric L Schwartz, PhD', 'role': 'PRINCIPAL_INVESTIGATOR', 'affiliation': 'Boston University'}]}, 'sponsorCollaboratorsModule': {'leadSponsor': {'name': 'Boston University', 'class': 'OTHER'}, 'collaborators': [{'name': 'Emory University', 'class': 'OTHER'}], 'responsibleParty': {'oldNameTitle': 'Professor Eric L. Schwartz', 'oldOrganization': 'Boston University'}}}}