Raw JSON
{'hasResults': False, 'derivedSection': {'miscInfoModule': {'versionHolder': '2025-12-24'}, 'conditionBrowseModule': {'meshes': [{'id': 'D016889', 'term': 'Endometrial Neoplasms'}, {'id': 'C565324', 'term': 'Parkinson Disease 4, Autosomal Dominant Lewy Body'}], 'ancestors': [{'id': 'D014594', 'term': 'Uterine Neoplasms'}, {'id': 'D005833', 'term': 'Genital Neoplasms, Female'}, {'id': 'D014565', 'term': 'Urogenital Neoplasms'}, {'id': 'D009371', 'term': 'Neoplasms by Site'}, {'id': 'D009369', 'term': 'Neoplasms'}, {'id': 'D014591', 'term': 'Uterine Diseases'}, {'id': 'D005831', 'term': 'Genital Diseases, Female'}, {'id': 'D052776', 'term': 'Female Urogenital Diseases'}, {'id': 'D005261', 'term': 'Female Urogenital Diseases and Pregnancy Complications'}, {'id': 'D000091642', 'term': 'Urogenital Diseases'}, {'id': 'D000091662', 'term': 'Genital Diseases'}]}, 'interventionBrowseModule': {'meshes': [{'id': 'C582435', 'term': 'pembrolizumab'}, {'id': 'D016190', 'term': 'Carboplatin'}, {'id': 'D017239', 'term': 'Paclitaxel'}, {'id': 'D000077143', 'term': 'Docetaxel'}], 'ancestors': [{'id': 'D056831', 'term': 'Coordination Complexes'}, {'id': 'D009930', 'term': 'Organic Chemicals'}, {'id': 'D043823', 'term': 'Taxoids'}, {'id': 'D043822', 'term': 'Cyclodecanes'}, {'id': 'D003516', 'term': 'Cycloparaffins'}, {'id': 'D006840', 'term': 'Hydrocarbons, Alicyclic'}, {'id': 'D006844', 'term': 'Hydrocarbons, Cyclic'}, {'id': 'D006838', 'term': 'Hydrocarbons'}, {'id': 'D004224', 'term': 'Diterpenes'}, {'id': 'D013729', 'term': 'Terpenes'}]}}, 'protocolSection': {'designModule': {'phases': ['PHASE3'], 'studyType': 'INTERVENTIONAL', 'designInfo': {'allocation': 'RANDOMIZED', 'maskingInfo': {'masking': 'SINGLE', 'whoMasked': ['OUTCOMES_ASSESSOR']}, 'primaryPurpose': 'TREATMENT', 'interventionModel': 'PARALLEL', 'interventionModelDescription': 'Participants are allocated to a single induction arm, then assigned randomly to either one of two maintenance treatment arms or one of two subsequent treatment arms.'}, 'enrollmentInfo': {'type': 'ESTIMATED', 'count': 1123}}, 'statusModule': {'overallStatus': 'RECRUITING', 'startDateStruct': {'date': '2025-05-22', 'type': 'ACTUAL'}, 'expandedAccessInfo': {'hasExpandedAccess': False}, 'statusVerifiedDate': '2025-12', 'completionDateStruct': {'date': '2032-05-24', 'type': 'ESTIMATED'}, 'lastUpdateSubmitDate': '2025-12-23', 'studyFirstSubmitDate': '2025-04-23', 'studyFirstSubmitQcDate': '2025-04-23', 'lastUpdatePostDateStruct': {'date': '2025-12-24', 'type': 'ACTUAL'}, 'studyFirstPostDateStruct': {'date': '2025-05-01', 'type': 'ACTUAL'}, 'primaryCompletionDateStruct': {'date': '2032-05-24', 'type': 'ESTIMATED'}}, 'outcomesModule': {'primaryOutcomes': [{'measure': 'Maintenance Treatment: Progression-Free Survival (PFS)', 'timeFrame': 'Up to approximately 44 months', 'description': 'PFS is defined as the time from randomization to the first documented progressive disease (PD) or death due to any cause, whichever occurs first as assessed by Response Criteria in Solid Tumors Version 1.1 (RECIST 1.1) as evaluated by the blinded independent central review (BICR). PD is defined as ≥20% increase in the sum of diameters of target lesions. In addition to the relative increase of 20%, the sum must also demonstrate an absolute increase of ≥5 mm. The appearance of one or more new lesions is also considered PD.'}, {'measure': 'Maintenance Treatment: Overall Survival (OS)', 'timeFrame': 'Up to approximately 54 months', 'description': 'OS is defined as time from randomization to death due to any cause.'}], 'secondaryOutcomes': [{'measure': 'Maintenance Treatment: Progression-Free Survival 2 (PFS2) as Assessed by Investigator', 'timeFrame': 'Up to approximately 54 months', 'description': 'PFS2 is defined as the time from randomization to the documented subsequent objective disease progression after initiation of new anticancer therapy or death due to any cause, whichever occurs first. PFS2 as assessed by the investigator will be presented.'}, {'measure': 'Maintenance Treatment: Number of Participants Who Experience One or More Adverse Events (AEs)', 'timeFrame': 'Up to approximately 27 months', 'description': 'An AE is any untoward medical occurrence in a clinical study participant, temporally associated with the use of study intervention, whether or not considered related to the study intervention.'}, {'measure': 'Maintenance Treatment: Number of Participants Who Discontinue Study Intervention Due to an AE', 'timeFrame': 'Up to approximately 24 months', 'description': 'An AE is any untoward medical occurrence in a clinical study participant, temporally associated with the use of study intervention, whether or not considered related to the study intervention.'}, {'measure': 'Maintenance Treatment: Change from baseline in European Organization for the Research and Treatment of Cancer Quality of Life Questionnaire Core 30 (EORTC QLQ-C30) Global Health Status (Item 29) and Quality of Life (Item 30) Item Mean Score', 'timeFrame': 'Baseline and up to approximately 24 months', 'description': 'EORTC QLQ-C30 is a 30-item scale to assess the overall quality of life of cancer patients. Participant responses to the questions "How would you rate your overall health during the past week?" and "How would you rate your overall quality of life during the past week?" are scored on a 7- point scale (1= Very poor to 7=Excellent). Using linear transformation, raw scores are standardized, so that scores range from 0 to 100. A higher score indicates a better overall health status. The change from baseline in EORTC QLQ-C30 Items 29 and 30 mean score will be presented.'}, {'measure': 'Maintenance Treatment: Change from baseline in EORTC QLQ-C30 Physical Functioning (Items 1-5) Combined Score', 'timeFrame': 'Baseline and up to approximately 24 months', 'description': "EORTC QLQ-C30 is a 30-item scale to assess the overall quality of life of cancer patients. The physical functioning score is based on participant responses to questions scored on a 4-point scale (1 = 'Not at All' to 4 = 'Very Much'). Higher scores indicate better physical functioning. The change from baseline in EORTC QLQ-C30 Physical Functioning (Items 1-5) combined score will be presented."}, {'measure': 'Maintenance Treatment: Change from baseline in EORTC QLQ-C30 Role Functioning (Items 6 and 7) Combined Score', 'timeFrame': 'Baseline and up to approximately 24 months', 'description': "EORTC QLQ-C30 is a 30-item scale to assess the overall quality of life of cancer patients. The role functioning score is based on participant responses to questions scored on a 4-point scale (1 = 'Not at All' to 4 = 'Very Much'). Higher scores indicate better role functioning. The change from baseline in EORTC QLQ-C30 Role Functioning (Items 6 and 7) combined score will be presented."}, {'measure': 'Maintenance Treatment: Change from baseline in EORTC QLQ Endometrial Cancer Symptom Score (QLQ-EN24)', 'timeFrame': 'Baseline and up to approximately 24 months', 'description': 'The EORTC-QLQ-EN24 is a 24-item questionnaire developed to be used in conjunction with the EORTC-QLQ-C30 to assess the quality of life of endometrial cancer patients. Participant responses are scored on a 4-point scale (1=not at all to 4=very much). A higher score indicates a better quality of life. The change from baseline in EORTC QLQ-E24 back and pelvis pain score will be presented.'}]}, 'oversightModule': {'oversightHasDmc': True, 'isFdaRegulatedDrug': True, 'isFdaRegulatedDevice': False}, 'conditionsModule': {'keywords': ['Programmed Cell Death-1 (PD1, PD-1)', 'Programmed Cell Death 1 Ligand 1 (PDL1, PD-L1)', 'Programmed Cell Death 1 Ligand 2 (PDL2, PD-L2)', 'Trophoblast cell surface antigen 2 (TROP2)'], 'conditions': ['Endometrial Cancer']}, 'referencesModule': {'seeAlsoLinks': [{'url': 'https://www.merckclinicaltrials.com/', 'label': 'Merck Clinical Trials Information'}]}, 'descriptionModule': {'briefSummary': 'Researchers are looking for new ways to treat people with proficient mismatch repair (pMMR) endometrial cancer (EC) that is advanced or recurrent.\n\n* EC is a type of cancer that starts in the tissues inside the uterus (womb)\n* pMMR indicates that certain normal proteins are present in the cancer cells\n* Advanced means the cancer has spread locally or to other parts of the body (metastatic) and cannot be removed with surgery\n* Recurrent means the cancer came back after surgery\n\nSacituzumab tirumotecan (also known as sac-TMT) and pembrolizumab are the study medicines. Sac-TMT is an antibody drug conjugate (ADC). An ADC attaches to specific targets on cancer cells and delivers treatment to destroy those cells.\n\nThe goal of this study is to learn if people who receive sac-TMT with pembrolizumab live longer and without the cancer getting worse compared to people who receive pembrolizumab alone.', 'detailedDescription': 'All participants undergo an initial Induction Phase of six cycles, each cycle consisting of pembrolizumab + carboplatin + paclitaxel or docetaxel. Each cycle is three weeks. Participants whose cancer does not progress enter the Maintenance Treatment Phase and are then randomly assigned to pembrolizumab + sac-TMT or pembrolizumab monotherapy. Participants whose cancer does progress will have the possibility to enter the Subsequent Treatment Phase and are then randomly assigned to pembrolizumab + sac-TMT or sac-TMT monotherapy.'}, 'eligibilityModule': {'sex': 'FEMALE', 'stdAges': ['ADULT', 'OLDER_ADULT'], 'minimumAge': '18 Years', 'healthyVolunteers': False, 'eligibilityCriteria': "Key inclusion criteria include but are not limited to:\n\n* Has a histologically confirmed diagnosis of primary advanced or recurrent endometrial carcinoma that has been confirmed as proficient mismatch repair (pMMR)\n* Has radiographically evaluable disease, with measurable Stage III or either measurable or non-measurable Stage IV or recurrent disease per Response Evaluation Criteria In Solid Tumors version 1.1 (RECIST 1.1), as assessed by the investigator.\n* Has received no prior systemic therapy for endometrial carcinoma except the following conditions as pre-specified by the protocol: 1 prior line of systemic platinum-based adjuvant and/or neoadjuvant chemotherapy in the setting of curative-intent, prior radiation with or without radiosensitizing chemotherapy if \\>2 weeks before the start of induction treatment, or prior hormonal therapy for treatment of endometrial carcinoma that was discontinued ≥1 week before the start of induction treatment\n\nKey exclusion criteria include but are not limited to:\n\n* Has carcinosarcoma, neuroendocrine tumors or endometrial sarcoma, including stromal sarcoma, leiomyosarcoma, adenosarcoma, or other types of sarcomas\n* Has endometrial carcinoma of any histology that is mismatch repair deficient (dMMR)\n* Is a candidate for curative-intent surgery or curative-intent radiotherapy at the time of enrollment\n* Has a history of documented severe dry eye syndrome, severe Meibomian gland disease and/or blepharitis, or severe corneal disease that prevents/delays corneal healing\n* Has active inflammatory bowel disease requiring immunosuppressive medication or previous history of inflammatory bowel disease\n* Has uncontrolled, significant cardiovascular disease or cerebrovascular disease\n* Human Immunodeficiency Virus-infected participants with a history of Kaposi's sarcoma and/or Multicentric Castleman's Disease\n* Received prior therapy in any setting with any of the following: anti-programmed cell death 1 protein, anti-programmed cell death ligand 1, anti-programmed cell death ligand 2 agent, or with an agent directed to another stimulatory or coinhibitory T-cell receptor; trophoblast cell surface antigen 2-targeted antibody drug conjugate; or topoisomerase I inhibitor-containing antibody drug conjugate"}, 'identificationModule': {'nctId': 'NCT06952504', 'acronym': 'TroFuse-033', 'briefTitle': 'A Study to Compare Sacituzumab Tirumotecan (MK-2870) in Combination With Pembrolizumab (MK-3475) Versus Pembrolizumab Alone as Treatment in Participants With Mismatch Repair Proficient Endometrial Cancer (MK-2870-033/TroFuse-033/GOG-3119/ENGOT-en29)', 'organization': {'class': 'INDUSTRY', 'fullName': 'Merck Sharp & Dohme LLC'}, 'officialTitle': 'A Phase 3 Randomized, Open-label, Multicenter Study to Compare the Efficacy and Safety of Sacituzumab Tirumotecan (Sac-TMT, MK-2870) in Combination With Pembrolizumab Versus Pembrolizumab Alone as First-line Maintenance Treatment in Participants With Mismatch Repair Proficient Endometrial Cancer (TroFuse-033/GOG-3119/ENGOT-en29)', 'orgStudyIdInfo': {'id': '2870-033'}, 'secondaryIdInfos': [{'id': '2024-519331-42-00', 'type': 'REGISTRY', 'domain': 'EU CT'}, {'id': 'U1111-1315-0794', 'type': 'REGISTRY', 'domain': 'UTN'}, {'id': 'GOG-3119', 'type': 'OTHER', 'domain': 'Gynecologic Oncology Group'}, {'id': 'ENGOT-en29', 'type': 'OTHER', 'domain': 'European Network for Gynaecological Oncological Trial groups'}, {'id': 'TroFuse-033', 'type': 'OTHER', 'domain': 'MSD'}, {'id': 'jRCT2011250020', 'type': 'REGISTRY', 'domain': 'Japan Registry of Clinical Trial (jRCT)'}]}, 'armsInterventionsModule': {'armGroups': [{'type': 'EXPERIMENTAL', 'label': 'Maintenance Treatment Arm A: Pembrolizumab + Sacituzumab Tirumotecan', 'description': 'During the Induction Phase, participants receive pembrolizumab 200 mg, carboplatin area under the curve (AUC) 5 (mg/mL/min), and paclitaxel 175 mg/m2 or docetaxel 75 mg/m2 on Day 1 of each 3-week cycle for 6 cycles (up to approximately 4 months).\n\nDuring the Maintenance Treatment Phase, participants receive sac-TMT 4 mg/kg on Days 1, 15, and 29 of each 6-week cycle and pembrolizumab 400 mg on Day 1 of each 6-week cycle for up to 14 cycles (up to approximately 19 months).', 'interventionNames': ['Biological: Pembrolizumab', 'Drug: Carboplatin', 'Drug: Paclitaxel', 'Drug: Docetaxel', 'Biological: Sacituzumab Tirumotecan']}, {'type': 'ACTIVE_COMPARATOR', 'label': 'Maintenance Treatment Arm B: Pembrolizumab Monotherapy', 'description': 'During the Induction Phase, participants receive pembrolizumab 200 mg, carboplatin AUC 5 (mg/mL/min), and paclitaxel 175 mg/m2 or docetaxel 75 mg/m2 on Day 1 of each 3-week cycle for 6 cycles (up to approximately 4 months).\n\nDuring the Maintenance Treatment Phase, participants receive pembrolizumab 400 mg on Day 1 of each 6-week cycle for up to 14 cycles (up to approximately 19 months).', 'interventionNames': ['Biological: Pembrolizumab', 'Drug: Carboplatin', 'Drug: Paclitaxel', 'Drug: Docetaxel']}, {'type': 'EXPERIMENTAL', 'label': 'Subsequent Treatment Arm A: Pembrolizumab + Sacituzumab Tirumotecan', 'description': 'During the Induction Phase, participants receive pembrolizumab 200 mg, carboplatin AUC 5 (mg/mL/min), and paclitaxel 175 mg/m2 or docetaxel 75 mg/m2 on Day 1 of each 3-week cycle for 6 cycles (up to approximately 4 months).\n\nDuring the Subsequent Treatment Phase, participants receive sac-TMT 4 mg/kg on Days 1, 15, and 29 of each 6-week cycle until discontinuation criteria is met and pembrolizumab 400 mg on Day 1 of each 6-week cycle for up to 14 cycles (up to approximately 19 months).', 'interventionNames': ['Biological: Pembrolizumab', 'Drug: Carboplatin', 'Drug: Paclitaxel', 'Drug: Docetaxel', 'Biological: Sacituzumab Tirumotecan']}, {'type': 'ACTIVE_COMPARATOR', 'label': 'Subsequent Treatment Arm B: Sacituzumab Tirumotecan Monotherapy', 'description': 'During the Induction Phase, participants receive pembrolizumab 200 mg, carboplatin AUC 5 (mg/mL/min), and paclitaxel 175 mg/m2 or docetaxel 75 mg/m2 on Day 1 of each 3-week cycle for 6 cycles (up to approximately 4 months).\n\nDuring the Subsequent Treatment Phase, participants receive sac-TMT 4 mg/kg on Days 1, 15, and 29 of each 6-week cycle until discontinuation criteria is met.', 'interventionNames': ['Drug: Carboplatin', 'Drug: Paclitaxel', 'Drug: Docetaxel', 'Biological: Sacituzumab Tirumotecan']}], 'interventions': [{'name': 'Pembrolizumab', 'type': 'BIOLOGICAL', 'otherNames': ['KEYTRUDA®', 'MK-3475', 'SCH 900475'], 'description': 'Intravenous (IV) Infusion', 'armGroupLabels': ['Maintenance Treatment Arm A: Pembrolizumab + Sacituzumab Tirumotecan', 'Maintenance Treatment Arm B: Pembrolizumab Monotherapy', 'Subsequent Treatment Arm A: Pembrolizumab + Sacituzumab Tirumotecan']}, {'name': 'Carboplatin', 'type': 'DRUG', 'description': 'During the Induction Phase, participants receive carboplatin AUC 5 (mg/mL/min) on Day 1 of each 3-week cycle for 6 cycles (up to approximately 4 months) via IV infusion.', 'armGroupLabels': ['Maintenance Treatment Arm A: Pembrolizumab + Sacituzumab Tirumotecan', 'Maintenance Treatment Arm B: Pembrolizumab Monotherapy', 'Subsequent Treatment Arm A: Pembrolizumab + Sacituzumab Tirumotecan', 'Subsequent Treatment Arm B: Sacituzumab Tirumotecan Monotherapy']}, {'name': 'Paclitaxel', 'type': 'DRUG', 'description': 'During the Induction Phase, participants receive paclitaxel 175 mg/m2 on Day 1 of each 3-week cycle for 6 cycles (up to approximately 4 months) via IV infusion.', 'armGroupLabels': ['Maintenance Treatment Arm A: Pembrolizumab + Sacituzumab Tirumotecan', 'Maintenance Treatment Arm B: Pembrolizumab Monotherapy', 'Subsequent Treatment Arm A: Pembrolizumab + Sacituzumab Tirumotecan', 'Subsequent Treatment Arm B: Sacituzumab Tirumotecan Monotherapy']}, {'name': 'Docetaxel', 'type': 'DRUG', 'description': 'During the Induction Phase, participants may receive docetaxel (in place of paclitaxel) 75 mg/m2 on Day 1 of each 3-week cycle for 6 cycles (up to approximately 4 months) via IV infusion.', 'armGroupLabels': ['Maintenance Treatment Arm A: Pembrolizumab + Sacituzumab Tirumotecan', 'Maintenance Treatment Arm B: Pembrolizumab Monotherapy', 'Subsequent Treatment Arm A: Pembrolizumab + Sacituzumab Tirumotecan', 'Subsequent Treatment Arm B: Sacituzumab Tirumotecan Monotherapy']}, {'name': 'Sacituzumab Tirumotecan', 'type': 'BIOLOGICAL', 'otherNames': ['sac-TMT', 'MK-2870', 'SKB264'], 'description': 'IV Infusion', 'armGroupLabels': ['Maintenance Treatment Arm A: Pembrolizumab + Sacituzumab Tirumotecan', 'Subsequent Treatment Arm A: Pembrolizumab + Sacituzumab Tirumotecan', 'Subsequent Treatment Arm B: Sacituzumab Tirumotecan Monotherapy']}]}, 'contactsLocationsModule': {'locations': [{'zip': '36604', 'city': 'Mobile', 'state': 'Alabama', 'status': 'RECRUITING', 'country': 'United States', 'contacts': [{'name': 'Study Coordinator', 'role': 'CONTACT', 'phone': '251-665-8000'}], 'facility': 'University of South Alabama, Mitchell Cancer Institute ( Site 6033)', 'geoPoint': {'lat': 30.69436, 'lon': -88.04305}}, {'zip': '99508', 'city': 'Anchorage', 'state': 'Alaska', 'status': 'RECRUITING', 'country': 'United States', 'contacts': [{'name': 'Study Coordinator', 'role': 'CONTACT', 'phone': '907-562-4673'}], 'facility': "Alaska Women's Cancer Care ( Site 6036)", 'geoPoint': {'lat': 61.21806, 'lon': -149.90028}}, {'zip': '92868', 'city': 'Orange', 'state': 'California', 'status': 'RECRUITING', 'country': 'United States', 'contacts': [{'name': 'Study Coordinator', 'role': 'CONTACT', 'phone': '949-813-1517'}], 'facility': 'University of California, Irvine (UCI) Health - UC Irvine Medical Center ( Site 6020)', 'geoPoint': {'lat': 33.78779, 'lon': -117.85311}}, {'zip': '20010', 'city': 'Washington D.C.', 'state': 'District of Columbia', 'status': 'RECRUITING', 'country': 'United States', 'contacts': [{'name': 'Study Coordinator', 'role': 'CONTACT', 'phone': '888-577-8839'}], 'facility': 'MedStar Washington Hospital Center ( Site 5005)', 'geoPoint': {'lat': 38.89511, 'lon': -77.03637}}, {'zip': '33901', 'city': 'Fort Myers', 'state': 'Florida', 'status': 'RECRUITING', 'country': 'United States', 'contacts': [{'name': 'Study Coordinator', 'role': 'CONTACT', 'phone': '239-274-9930'}], 'facility': 'Florida Cancer Specialists - South ( Site 7003)', 'geoPoint': {'lat': 26.62168, 'lon': -81.84059}}, {'zip': '32608', 'city': 'Gainesville', 'state': 'Florida', 'status': 'RECRUITING', 'country': 'United States', 'contacts': [{'name': 'Study Coordinator', 'role': 'CONTACT', 'phone': '352-273-7832'}], 'facility': 'UF Health Davis Cancer Pavilion and Shands Med Plaza ( Site 6026)', 'geoPoint': {'lat': 29.65163, 'lon': -82.32483}}, {'zip': '33140', 'city': 'Miami Beach', 'state': 'Florida', 'status': 'RECRUITING', 'country': 'United States', 'contacts': [{'name': 'Study Coordinator', 'role': 'CONTACT', 'phone': '305-674-2625'}], 'facility': 'Mount Sinai Cancer Center ( Site 6031)', 'geoPoint': {'lat': 25.79065, 'lon': -80.13005}}, {'zip': '33701', 'city': 'St. Petersburg', 'state': 'Florida', 'status': 'RECRUITING', 'country': 'United States', 'contacts': [{'name': 'Study Coordinator', 'role': 'CONTACT', 'phone': '727-522-0558'}], 'facility': 'Florida Cancer Specialists ( Site 7002)', 'geoPoint': {'lat': 27.77086, 'lon': -82.67927}}, {'zip': '33401', 'city': 'West Palm Beach', 'state': 'Florida', 'status': 'RECRUITING', 'country': 'United States', 'contacts': [{'name': 'Study Coordinator', 'role': 'CONTACT', 'phone': '561-366-4100'}], 'facility': 'Florida Cancer Specialists East ( Site 7001)', 'geoPoint': {'lat': 26.71534, 'lon': -80.05337}}, {'zip': '31405', 'city': 'Savannah', 'state': 'Georgia', 'status': 'RECRUITING', 'country': 'United States', 'contacts': [{'name': 'Study Coordinator', 'role': 'CONTACT', 'phone': '912-819-5704'}], 'facility': "St. Joseph's/Candler Health System ( Site 6021)", 'geoPoint': {'lat': 32.08354, 'lon': -81.09983}}, {'zip': '60637', 'city': 'Chicago', 'state': 'Illinois', 'status': 'RECRUITING', 'country': 'United States', 'contacts': [{'name': 'Study Coordinator', 'role': 'CONTACT', 'phone': '773-702-1220'}], 'facility': 'University of Chicago Medical Center ( Site 5002)', 'geoPoint': {'lat': 41.85003, 'lon': -87.65005}}, {'zip': '46845', 'city': 'Fort Wayne', 'state': 'Indiana', 'status': 'RECRUITING', 'country': 'United States', 'contacts': [{'name': 'Study Coordinator', 'role': 'CONTACT', 'phone': '800-724-8326'}], 'facility': 'Parkview Research Center ( Site 6008)', 'geoPoint': {'lat': 41.1306, 'lon': -85.12886}}, {'zip': '70433', 'city': 'Covington', 'state': 'Louisiana', 'status': 'RECRUITING', 'country': 'United States', 'contacts': [{'name': 'Study Coordinator', 'role': 'CONTACT', 'phone': '985-317-6005'}], 'facility': "Women's Cancer Care ( Site 6010)", 'geoPoint': {'lat': 30.47549, 'lon': -90.10042}}, {'zip': '71103', 'city': 'Shreveport', 'state': 'Louisiana', 'status': 'RECRUITING', 'country': 'United States', 'contacts': [{'name': 'Study Coordinator', 'role': 'CONTACT', 'phone': '318-408-1198'}], 'facility': 'TRIALS 365 ( Site 6005)', 'geoPoint': {'lat': 32.52515, 'lon': -93.75018}}, {'zip': '04074', 'city': 'Scarborough', 'state': 'Maine', 'status': 'RECRUITING', 'country': 'United States', 'contacts': [{'name': 'Study Coordinator', 'role': 'CONTACT', 'phone': '207-396-7089'}], 'facility': 'Maine Medical Center - Scarborough Campus ( Site 6042)', 'geoPoint': {'lat': 43.57814, 'lon': -70.32172}}, {'zip': '55404', 'city': 'Minneapolis', 'state': 'Minnesota', 'status': 'RECRUITING', 'country': 'United States', 'contacts': [{'name': 'Study Coordinator', 'role': 'CONTACT', 'phone': '817-837-8660'}], 'facility': 'Minnesota Oncology Hematology, PA ( Site 8003)', 'geoPoint': {'lat': 44.97997, 'lon': -93.26384}}, {'zip': '39216', 'city': 'Jackson', 'state': 'Mississippi', 'status': 'RECRUITING', 'country': 'United States', 'contacts': [{'name': 'Study Coordinator', 'role': 'CONTACT', 'phone': '601-200-4970'}], 'facility': "St. Dominic's Hospital ( Site 5004)", 'geoPoint': {'lat': 32.29876, 'lon': -90.18481}}, {'zip': '07666', 'city': 'Teaneck', 'state': 'New Jersey', 'status': 'RECRUITING', 'country': 'United States', 'contacts': [{'name': 'Study Coordinator', 'role': 'CONTACT', 'phone': '201-227-6200'}], 'facility': 'Holy Name Medical Center ( Site 6011)', 'geoPoint': {'lat': 40.8976, 'lon': -74.01597}}, {'zip': '87131', 'city': 'Albuquerque', 'state': 'New Mexico', 'status': 'RECRUITING', 'country': 'United States', 'contacts': [{'name': 'Study Coordinator', 'role': 'CONTACT', 'phone': '505-272-4946'}], 'facility': 'University of New Mexico Comprehensive Cancer Center ( Site 6046)', 'geoPoint': {'lat': 35.08449, 'lon': -106.65114}}, {'zip': '11501', 'city': 'Mineola', 'state': 'New York', 'status': 'RECRUITING', 'country': 'United States', 'contacts': [{'name': 'Study Coordinator', 'role': 'CONTACT', 'phone': '516-708-4821'}], 'facility': 'Perlmutter Cancer Center at NYU Langone Hospital - Long Island ( Site 6055)', 'geoPoint': {'lat': 40.74927, 'lon': -73.64068}}, {'zip': '10016', 'city': 'New York', 'state': 'New York', 'status': 'RECRUITING', 'country': 'United States', 'contacts': [{'name': 'Study Coordinator', 'role': 'CONTACT', 'phone': '212-731-6455'}], 'facility': 'Laura and Isaac Perlmutter Cancer Center at NYU Langone ( Site 6004)', 'geoPoint': {'lat': 40.71427, 'lon': -74.00597}}, {'zip': '27710', 'city': 'Durham', 'state': 'North Carolina', 'status': 'RECRUITING', 'country': 'United States', 'contacts': [{'name': 'Study Coordinator', 'role': 'CONTACT', 'phone': '919-684-3780'}], 'facility': 'Duke Cancer Institute ( Site 6049)', 'geoPoint': {'lat': 35.99403, 'lon': -78.89862}}, {'zip': '28374', 'city': 'Pinehurst', 'state': 'North Carolina', 'status': 'RECRUITING', 'country': 'United States', 'contacts': [{'name': 'Study Coordinator', 'role': 'CONTACT', 'phone': '910-715-8684'}], 'facility': 'FirstHealth of the Carolinas ( Site 6037)', 'geoPoint': {'lat': 35.19543, 'lon': -79.46948}}, {'zip': '45459', 'city': 'Centerville', 'state': 'Ohio', 'status': 'RECRUITING', 'country': 'United States', 'contacts': [{'name': 'Study Coordinator', 'role': 'CONTACT', 'phone': '937-438-7800'}], 'facility': 'Miami Valley Hospital South ( Site 6014)', 'geoPoint': {'lat': 39.62839, 'lon': -84.15938}}, {'zip': '74146', 'city': 'Tulsa', 'state': 'Oklahoma', 'status': 'RECRUITING', 'country': 'United States', 'contacts': [{'name': 'Study Coordinator', 'role': 'CONTACT', 'phone': '918-505-3200'}], 'facility': 'Oklahoma Cancer Specialists and Research Institute, LLC ( Site 6047)', 'geoPoint': {'lat': 36.15398, 'lon': -95.99277}}, {'zip': '18015', 'city': 'Bethlehem', 'state': 'Pennsylvania', 'status': 'RECRUITING', 'country': 'United States', 'contacts': [{'name': 'Study Coordinator', 'role': 'CONTACT', 'phone': '484-503-4673'}], 'facility': "St. Luke's University Health Network ( Site 6041)", 'geoPoint': {'lat': 40.62593, 'lon': -75.37046}}, {'zip': '19104', 'city': 'Philadelphia', 'state': 'Pennsylvania', 'status': 'RECRUITING', 'country': 'United States', 'contacts': [{'name': 'Study Coordinator', 'role': 'CONTACT', 'phone': '215-662-2487'}], 'facility': 'Hospital of the University of Pennsylvania ( Site 5007)', 'geoPoint': {'lat': 39.95238, 'lon': -75.16362}}, {'zip': '19104', 'city': 'Philadelphia', 'state': 'Pennsylvania', 'status': 'RECRUITING', 'country': 'United States', 'contacts': [{'name': 'Study Coordinator', 'role': 'CONTACT', 'phone': '215-662-2487'}], 'facility': 'Hospital of the University of Pennsylvania ( Site 6023)', 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