Ignite Creation Date:
2025-12-24 @ 8:02 PM
Ignite Modification Date:
2025-12-25 @ 5:35 PM
Study NCT ID:
NCT00231504
Status:
COMPLETED
Last Update Posted:
2010-01-06
First Post:
2005-10-03
Is NOT Gene Therapy:
False
Has Adverse Events:
False
Brief Title:
Study of Follicle Stimulating Hormone (FSH) Receptor in Women With Low Antral Follicle Count
Sponsor:
Organization:
Raw JSON
{'hasResults': False, 'derivedSection': {'miscInfoModule': {'versionHolder': '2025-12-24'}, 'interventionBrowseModule': {'meshes': [{'id': 'D001800', 'term': 'Blood Specimen Collection'}], 'ancestors': [{'id': 'D013048', 'term': 'Specimen Handling'}, {'id': 'D019411', 'term': 'Clinical Laboratory Techniques'}, {'id': 'D019937', 'term': 'Diagnostic Techniques and Procedures'}, {'id': 'D003933', 'term': 'Diagnosis'}, {'id': 'D011677', 'term': 'Punctures'}, {'id': 'D013514', 'term': 'Surgical Procedures, Operative'}, {'id': 'D008919', 'term': 'Investigative Techniques'}]}}, 'protocolSection': {'designModule': {'bioSpec': {'retention': 'SAMPLES_WITH_DNA', 'description': 'DNA'}, 'studyType': 'OBSERVATIONAL', 'designInfo': {'timePerspective': 'PROSPECTIVE', 'observationalModel': 'COHORT'}, 'enrollmentInfo': {'type': 'ACTUAL', 'count': 82}}, 'statusModule': {'overallStatus': 'COMPLETED', 'startDateStruct': {'date': '2005-10'}, 'expandedAccessInfo': {'hasExpandedAccess': False}, 'statusVerifiedDate': '2007-03', 'completionDateStruct': {'date': '2009-05', 'type': 'ACTUAL'}, 'lastUpdateSubmitDate': '2010-01-05', 'studyFirstSubmitDate': '2005-10-03', 'studyFirstSubmitQcDate': '2005-10-03', 'lastUpdatePostDateStruct': {'date': '2010-01-06', 'type': 'ESTIMATED'}, 'studyFirstPostDateStruct': {'date': '2005-10-04', 'type': 'ESTIMATED'}, 'primaryCompletionDateStruct': {'date': '2009-03', 'type': 'ACTUAL'}}, 'oversightModule': {'oversightHasDmc': True}, 'conditionsModule': {'keywords': ['Polymorphism P1', 'Polymorphism P2', 'FSH Receptor', 'Antral follicle count', 'FSH receptor polymorphism'], 'conditions': ['Antral Follicle Deficit', 'Fertility']}, 'descriptionModule': {'briefSummary': 'The deficit in the total number of antral follicles is associated with a reduction of the ovarian fertility potential in young women.\n\nThe principal objective of this study is to evaluate the relationship between FSH receptor polymorphism and antral follicle count.\n\nThe investigators have designed a study of FSH receptor polymorphisms P1 and P2 as an association with a low antral follicle count in the ovary.', 'detailedDescription': 'The present study will compare the prevalence of FSH receptor polymorphisms P1 and P2 in women having reduced follicle count (1 to 9 antral follicles) or normal follicle count (13 to 20 antral follicles) determined by ultrasound scans.'}, 'eligibilityModule': {'sex': 'FEMALE', 'stdAges': ['ADULT'], 'maximumAge': '35 Years', 'minimumAge': '18 Years', 'samplingMethod': 'NON_PROBABILITY_SAMPLE', 'studyPopulation': 'YOUNG WOMAN', 'healthyVolunteers': True, 'eligibilityCriteria': 'Inclusion Criteria:\n\n* 18 to 35 years old\n* 1 to 9 or 13 to 20 antral follicles\n* Caucasian, occidental Europe\n* Presence of both ovaries\n* Informed consent\n\nExclusion Criteria:\n\n* Ovarian anomalies\n* Menopause\n* Pregnancy\n* Other diseases'}, 'identificationModule': {'nctId': 'NCT00231504', 'briefTitle': 'Study of Follicle Stimulating Hormone (FSH) Receptor in Women With Low Antral Follicle Count', 'organization': {'class': 'OTHER', 'fullName': 'Assistance Publique - Hôpitaux de Paris'}, 'officialTitle': 'Study of Follicle Stimulating Hormone (FSH) Receptor in Women With Low Antral Follicle Count', 'orgStudyIdInfo': {'id': 'P041013'}, 'secondaryIdInfos': [{'id': 'CRC04140'}]}, 'armsInterventionsModule': {'interventions': [{'name': 'Blood samples', 'type': 'PROCEDURE', 'description': 'Blood samples'}]}, 'contactsLocationsModule': {'locations': [{'zip': '92140', 'city': 'Paris', 'country': 'France', 'facility': 'Antoine Beclere Hospital, Obstetrics and Gynaecology and Reproduction Medicine Service', 'geoPoint': {'lat': 48.85341, 'lon': 2.3488}}], 'overallOfficials': [{'name': 'Renato FANCHIN, MD', 'role': 'PRINCIPAL_INVESTIGATOR', 'affiliation': 'Assistance Publique - Hôpitaux de Paris'}]}, 'sponsorCollaboratorsModule': {'leadSponsor': {'name': 'Assistance Publique - Hôpitaux de Paris', 'class': 'OTHER'}, 'responsibleParty': {'oldNameTitle': 'Christophe Aucan', 'oldOrganization': 'Department Clinical Rechearch of Developpement'}}}}