Ignite Creation Date:
2025-12-24 @ 7:52 PM
Ignite Modification Date:
2025-12-31 @ 7:56 AM
Study NCT ID:
NCT00752804
Status:
COMPLETED
Last Update Posted:
2022-12-15
First Post:
2008-09-12
Is NOT Gene Therapy:
True
Has Adverse Events:
False
Brief Title:
Uremic Toxins in the ICU: Patients After Cardiac Surgery
Sponsor:
Organization:
Raw JSON
{'hasResults': False, 'derivedSection': {'miscInfoModule': {'versionHolder': '2025-12-24'}, 'conditionBrowseModule': {'meshes': [{'id': 'D051437', 'term': 'Renal Insufficiency'}], 'ancestors': [{'id': 'D007674', 'term': 'Kidney Diseases'}, {'id': 'D014570', 'term': 'Urologic Diseases'}, {'id': 'D052776', 'term': 'Female Urogenital Diseases'}, {'id': 'D005261', 'term': 'Female Urogenital Diseases and Pregnancy Complications'}, {'id': 'D000091642', 'term': 'Urogenital Diseases'}, {'id': 'D052801', 'term': 'Male Urogenital Diseases'}]}}, 'protocolSection': {'designModule': {'phases': ['NA'], 'studyType': 'INTERVENTIONAL', 'designInfo': {'allocation': 'RANDOMIZED', 'maskingInfo': {'masking': 'NONE'}, 'primaryPurpose': 'TREATMENT', 'interventionModel': 'CROSSOVER'}, 'enrollmentInfo': {'type': 'ACTUAL', 'count': 9}}, 'statusModule': {'overallStatus': 'COMPLETED', 'startDateStruct': {'date': '2008-07-31', 'type': 'ACTUAL'}, 'expandedAccessInfo': {'hasExpandedAccess': False}, 'statusVerifiedDate': '2022-12', 'completionDateStruct': {'date': '2013-12-31', 'type': 'ACTUAL'}, 'lastUpdateSubmitDate': '2022-12-14', 'studyFirstSubmitDate': '2008-09-12', 'studyFirstSubmitQcDate': '2008-09-12', 'lastUpdatePostDateStruct': {'date': '2022-12-15', 'type': 'ACTUAL'}, 'studyFirstPostDateStruct': {'date': '2008-09-15', 'type': 'ESTIMATED'}, 'primaryCompletionDateStruct': {'date': '2013-10-04', 'type': 'ACTUAL'}}, 'outcomesModule': {'primaryOutcomes': [{'measure': 'Toxin removal', 'timeFrame': 'During dialysis'}]}, 'oversightModule': {'oversightHasDmc': False}, 'conditionsModule': {'keywords': ['ICU patients with acute renal failure after cardiac surgery'], 'conditions': ['Renal Failure']}, 'referencesModule': {'seeAlsoLinks': [{'url': 'http://www.uzgent.be', 'label': 'Website of the University Hospital Ghent'}]}, 'descriptionModule': {'briefSummary': 'Study of the kinetics of uremic toxins in the ICU patients with acute renal failure, in order to optimize the dialysis dose: patients after cardiac surgery.The sampling of blood and dialysate will be done during dialyses with different durations (4, 6 and 8h)'}, 'eligibilityModule': {'sex': 'ALL', 'stdAges': ['ADULT', 'OLDER_ADULT'], 'minimumAge': '18 Years', 'healthyVolunteers': False, 'eligibilityCriteria': 'Inclusion Criteria:\n\n* ICU patients after cardiac surgery with acute renal failure'}, 'identificationModule': {'nctId': 'NCT00752804', 'briefTitle': 'Uremic Toxins in the ICU: Patients After Cardiac Surgery', 'organization': {'class': 'OTHER', 'fullName': 'University Hospital, Ghent'}, 'officialTitle': 'Study of the Kinetics of Uremic Toxins in the ICU Patients With Acute Renal Failure, in Order to Optimize the Dialysis Dose: Patients After Cardiac Surgery', 'orgStudyIdInfo': {'id': '2008/374'}}, 'armsInterventionsModule': {'armGroups': [{'type': 'EXPERIMENTAL', 'label': '1', 'description': 'Dialysis during 4 hours', 'interventionNames': ['Procedure: Dialysis during 4 hours']}, {'type': 'ACTIVE_COMPARATOR', 'label': '2', 'description': 'Dialysis during 6 hours', 'interventionNames': ['Procedure: Dialysis during 6 hours']}, {'type': 'ACTIVE_COMPARATOR', 'label': '3', 'description': 'Dialysis during 8 hours', 'interventionNames': ['Procedure: Dialysis during 8 hours']}], 'interventions': [{'name': 'Dialysis during 4 hours', 'type': 'PROCEDURE', 'description': 'Blood and dialysate sampling', 'armGroupLabels': ['1']}, {'name': 'Dialysis during 6 hours', 'type': 'PROCEDURE', 'description': 'Blood and dialysate sampling', 'armGroupLabels': ['2']}, {'name': 'Dialysis during 8 hours', 'type': 'PROCEDURE', 'description': 'Blood and dialysate sampling', 'armGroupLabels': ['3']}]}, 'contactsLocationsModule': {'locations': [{'zip': '9000', 'city': 'Ghent', 'country': 'Belgium', 'facility': 'University Hospital Ghent', 'geoPoint': {'lat': 51.05, 'lon': 3.71667}}], 'overallOfficials': [{'name': 'Raymond Vanholder, MD, PhD', 'role': 'PRINCIPAL_INVESTIGATOR', 'affiliation': 'University Hospital, Ghent'}]}, 'sponsorCollaboratorsModule': {'leadSponsor': {'name': 'University Hospital, Ghent', 'class': 'OTHER'}, 'responsibleParty': {'type': 'SPONSOR'}}}}