Ignite Creation Date:
2025-12-24 @ 7:47 PM
Ignite Modification Date:
2025-12-29 @ 8:48 AM
Study NCT ID:
NCT05680103
Status:
UNKNOWN
Last Update Posted:
2023-03-01
First Post:
2022-12-25
Is NOT Gene Therapy:
True
Has Adverse Events:
False
Brief Title:
Correlation Between Occlussion Types , in Patients With Temporomandibular Disorders.
Sponsor:
Organization:
Raw JSON
{'hasResults': False, 'derivedSection': {'miscInfoModule': {'versionHolder': '2025-12-24'}, 'conditionBrowseModule': {'meshes': [{'id': 'D013705', 'term': 'Temporomandibular Joint Disorders'}], 'ancestors': [{'id': 'D017271', 'term': 'Craniomandibular Disorders'}, {'id': 'D008336', 'term': 'Mandibular Diseases'}, {'id': 'D007571', 'term': 'Jaw Diseases'}, {'id': 'D009140', 'term': 'Musculoskeletal Diseases'}, {'id': 'D007592', 'term': 'Joint Diseases'}, {'id': 'D009135', 'term': 'Muscular Diseases'}, {'id': 'D009057', 'term': 'Stomatognathic Diseases'}]}}, 'protocolSection': {'designModule': {'studyType': 'OBSERVATIONAL', 'designInfo': {'timePerspective': 'CROSS_SECTIONAL', 'observationalModel': 'COHORT'}, 'enrollmentInfo': {'type': 'ESTIMATED', 'count': 200}, 'targetDuration': '2 Weeks', 'patientRegistry': True}, 'statusModule': {'overallStatus': 'UNKNOWN', 'lastKnownStatus': 'NOT_YET_RECRUITING', 'startDateStruct': {'date': '2023-03', 'type': 'ESTIMATED'}, 'expandedAccessInfo': {'hasExpandedAccess': False}, 'statusVerifiedDate': '2023-02', 'completionDateStruct': {'date': '2024-02', 'type': 'ESTIMATED'}, 'lastUpdateSubmitDate': '2023-02-26', 'studyFirstSubmitDate': '2022-12-25', 'studyFirstSubmitQcDate': '2022-12-25', 'lastUpdatePostDateStruct': {'date': '2023-03-01', 'type': 'ACTUAL'}, 'studyFirstPostDateStruct': {'date': '2023-01-11', 'type': 'ACTUAL'}, 'primaryCompletionDateStruct': {'date': '2024-01', 'type': 'ESTIMATED'}}, 'outcomesModule': {'primaryOutcomes': [{'measure': 'Prevalence of ADDwR in patients with class III malocclusion', 'timeFrame': 'baseline', 'description': 'lateral cephalometry will be taken for patients with TMDs and then measurements will be done to calculate SNA and SNB to see Prevalence of ADDwR in patients with class III malocclusion'}], 'secondaryOutcomes': [{'measure': 'Prevalence of ADDwR in patients with class I and class II malocclusion', 'timeFrame': 'baseline', 'description': 'lateral cephalometry will be taken for patients with TMDs and then measurements will be done to calculate SNA and SNB to see Prevalence of ADDwR in patients with class I and class II malocclusion'}]}, 'oversightModule': {'isFdaRegulatedDrug': False, 'isFdaRegulatedDevice': False}, 'conditionsModule': {'conditions': ['Temporomandibular Disorder']}, 'referencesModule': {'references': [{'pmid': '20633336', 'type': 'BACKGROUND', 'citation': 'Maizlin ZV, Nutiu N, Dent PB, Vos PM, Fenton DM, Kirby JM, Vora P, Gillies JH, Clement JJ. Displacement of the temporomandibular joint disk: correlation between clinical findings and MRI characteristics. J Can Dent Assoc. 2010;76:a3.'}, {'pmid': '21723023', 'type': 'BACKGROUND', 'citation': 'Cai XY, Jin JM, Yang C. Changes in disc position, disc length, and condylar height in the temporomandibular joint with anterior disc displacement: a longitudinal retrospective magnetic resonance imaging study. J Oral Maxillofac Surg. 2011 Nov;69(11):e340-6. doi: 10.1016/j.joms.2011.02.038. Epub 2011 Jul 1.'}]}, 'descriptionModule': {'briefSummary': 'study to find if there is correlation between occlusion types and TMD or not', 'detailedDescription': 'The relationship among occlusion, condylar position and temporomandibular disorders (TMDs) has been part of an extensive discussion in the dental field. There is a strong belief that the discrepancy between the centric relation (CR) and the intercuspal position (ICP) could predispose to the presence of TMDs . It was suggested in the past in the earlier studies that TMD is more common among the individuals who have Angle class II and class III , malocclusion , open bite , and cross bite . In the 1990s, studies suggested that some occlusal and skeletal characteristics as anterior open bite, unilateral posterior crossbite, overjet greater than 6-7mm, absence of five or more posterior teeth and CR to maximum intercuspation (MI) discrepancy greater than 2mm could be considered occlusal risk factors for TMDs . In their study, Oyetola et al. reported that 25% of the evaluated TMD patients had malocclusion Yet, recently with studies and systematic reviews , this idea ( alocclusion is the main cause of TMD) started to lose its support, and many studies showed that sensitivity to nociceptive stimulations and psychological factors are of more importance in the etiology of TMD'}, 'eligibilityModule': {'sex': 'ALL', 'stdAges': ['CHILD', 'ADULT'], 'maximumAge': '50 Years', 'minimumAge': '16 Years', 'samplingMethod': 'NON_PROBABILITY_SAMPLE', 'studyPopulation': 'patients with TMDs and have teeth for dental occlussion', 'healthyVolunteers': True, 'eligibilityCriteria': 'Inclusion Criteria:\n\n1. Patients above 16 years old and below 50\n2. Patients with TMD diagnosed (stage 2 Wilkes classification , anterior disc displacement with reduction, )\n3. Provided informed consent.\n4. No history of systemic condition affecting TMJ\n5. No previous orthodontic ttt\n\nExclusion Criteria:\n\n1. Ear diseases.\n2. History of facial trauma.\n3. Neurological or oncological disease.'}, 'identificationModule': {'nctId': 'NCT05680103', 'briefTitle': 'Correlation Between Occlussion Types , in Patients With Temporomandibular Disorders.', 'organization': {'class': 'OTHER', 'fullName': 'Cairo University'}, 'officialTitle': 'Correlation Between Occlussion Types , in Patients With Temporomandibular Disorders. : A Cross Sectional Study', 'orgStudyIdInfo': {'id': 'occlussion and TMDs'}}, 'armsInterventionsModule': {'interventions': [{'name': 'lateral cephalometry', 'type': 'RADIATION', 'description': 'lateral x-ray beam to capture lateral cephalometry of patients'}]}, 'contactsLocationsModule': {'centralContacts': [{'name': 'Mina Habib, Bds', 'role': 'CONTACT', 'email': 'mina_armia@dentistry.cu.edu.eg', 'phone': '+201207337835'}, {'name': 'Omnia ABD - Elaziz, PhD', 'role': 'CONTACT', 'email': 'omniya.abdelaziz@gmail.com'}]}, 'sponsorCollaboratorsModule': {'leadSponsor': {'name': 'Cairo University', 'class': 'OTHER'}, 'responsibleParty': {'type': 'PRINCIPAL_INVESTIGATOR', 'investigatorTitle': 'Principal Investigator', 'investigatorFullName': 'Mina Armia Zaki', 'investigatorAffiliation': 'Cairo University'}}}}