Ignite Creation Date:
2025-12-24 @ 7:43 PM
Ignite Modification Date:
2026-02-25 @ 11:47 PM
Study NCT ID:
NCT02573103
Status:
COMPLETED
Last Update Posted:
2018-07-12
First Post:
2015-09-28
Is Gene Therapy:
True
Has Adverse Events:
False
Brief Title:
Air Pollution and Cardiovascular Disease
Sponsor:
Organization:
Raw JSON
{'hasResults': False, 'derivedSection': {'miscInfoModule': {'versionHolder': '2025-12-24'}, 'conditionBrowseModule': {'meshes': [{'id': 'D008659', 'term': 'Metabolic Diseases'}], 'ancestors': [{'id': 'D009750', 'term': 'Nutritional and Metabolic Diseases'}]}}, 'protocolSection': {'designModule': {'bioSpec': {'retention': 'SAMPLES_WITHOUT_DNA', 'description': 'plasma and urine'}, 'studyType': 'OBSERVATIONAL', 'designInfo': {'timePerspective': 'PROSPECTIVE', 'observationalModel': 'COHORT'}, 'enrollmentInfo': {'type': 'ACTUAL', 'count': 73}, 'patientRegistry': False}, 'statusModule': {'overallStatus': 'COMPLETED', 'startDateStruct': {'date': '2014-11'}, 'expandedAccessInfo': {'hasExpandedAccess': False}, 'statusVerifiedDate': '2018-07', 'completionDateStruct': {'date': '2016-01', 'type': 'ACTUAL'}, 'lastUpdateSubmitDate': '2018-07-10', 'studyFirstSubmitDate': '2015-09-28', 'studyFirstSubmitQcDate': '2015-10-07', 'lastUpdatePostDateStruct': {'date': '2018-07-12', 'type': 'ACTUAL'}, 'studyFirstPostDateStruct': {'date': '2015-10-09', 'type': 'ESTIMATED'}, 'primaryCompletionDateStruct': {'date': '2016-01', 'type': 'ACTUAL'}}, 'outcomesModule': {'primaryOutcomes': [{'measure': 'Dyslipidemia', 'timeFrame': 'One year', 'description': 'Analyzed HDL by Beckman AU5800'}], 'secondaryOutcomes': [{'measure': 'System oxidative stress', 'timeFrame': 'One year', 'description': 'Analyzed oxidative stress biomarkers,such as MDA by HPLC'}]}, 'oversightModule': {'oversightHasDmc': True}, 'conditionsModule': {'conditions': ['Metabolic Disorder']}, 'descriptionModule': {'briefSummary': 'To determine the effects of ambient airpollution exposures on cardiovascular responses among healthy adults without cardiovascular disease.'}, 'eligibilityModule': {'sex': 'ALL', 'stdAges': ['ADULT'], 'maximumAge': '50 Years', 'minimumAge': '18 Years', 'samplingMethod': 'NON_PROBABILITY_SAMPLE', 'studyPopulation': 'We will maintain enrollment criteria of the in-progress study being healthy adults without CV disease or risk factors', 'healthyVolunteers': True, 'eligibilityCriteria': 'Inclusion Criteria:\n\n* without CV disease or risk factors (e.g., hypertension, diabetes, or treated hyperlipidemia). Subjects are non-smokers in non-smoking household.\n\nExclusion Criteria:\n\n* Screening visit BP\\>140/90 mm Hg, fasting glucose \\>126 mg/dL, or positive urine pregnancy test (females). Subjects cannot be taking any medications or over-the-counter drugs that affect CV function.'}, 'identificationModule': {'nctId': 'NCT02573103', 'briefTitle': 'Air Pollution and Cardiovascular Disease', 'organization': {'class': 'OTHER', 'fullName': 'Peking University'}, 'officialTitle': 'Air Pollution and Cardiovascular Disease', 'orgStudyIdInfo': {'id': 'WHuang'}}, 'contactsLocationsModule': {'overallOfficials': [{'name': 'Wei Huang, PhD', 'role': 'PRINCIPAL_INVESTIGATOR', 'affiliation': 'Peking University School of Public Health'}]}, 'sponsorCollaboratorsModule': {'leadSponsor': {'name': 'WeiHuang', 'class': 'OTHER'}, 'responsibleParty': {'type': 'SPONSOR_INVESTIGATOR', 'investigatorTitle': 'Peking University School of Public Health', 'investigatorFullName': 'WeiHuang', 'investigatorAffiliation': 'Peking University'}}}}