Ignite Creation Date:
2025-12-24 @ 7:32 PM
Ignite Modification Date:
2025-12-29 @ 4:11 PM
Study NCT ID:
NCT05106803
Status:
COMPLETED
Last Update Posted:
2021-11-04
First Post:
2021-10-24
Is NOT Gene Therapy:
True
Has Adverse Events:
False
Brief Title:
Antibiotic Profile of Pathogenic Bacteria Isolated in Public Hospitals in Northern Jordan
Sponsor:
Organization:
Raw JSON
{'hasResults': False, 'derivedSection': {'miscInfoModule': {'versionHolder': '2025-12-24'}, 'conditionBrowseModule': {'meshes': [{'id': 'D001424', 'term': 'Bacterial Infections'}, {'id': 'D013530', 'term': 'Surgical Wound Infection'}], 'ancestors': [{'id': 'D001423', 'term': 'Bacterial Infections and Mycoses'}, {'id': 'D007239', 'term': 'Infections'}, {'id': 'D014946', 'term': 'Wound Infection'}, {'id': 'D011183', 'term': 'Postoperative Complications'}, {'id': 'D010335', 'term': 'Pathologic Processes'}, {'id': 'D013568', 'term': 'Pathological Conditions, Signs and Symptoms'}]}, 'interventionBrowseModule': {'meshes': [{'id': 'D002939', 'term': 'Ciprofloxacin'}, {'id': 'D015662', 'term': 'Trimethoprim, Sulfamethoxazole Drug Combination'}, {'id': 'D009643', 'term': 'Norfloxacin'}, {'id': 'D004917', 'term': 'Erythromycin'}, {'id': 'D002701', 'term': 'Chloramphenicol'}, {'id': 'D005839', 'term': 'Gentamicins'}, {'id': 'D013752', 'term': 'Tetracycline'}, {'id': 'D014640', 'term': 'Vancomycin'}, {'id': 'D019980', 'term': 'Amoxicillin-Potassium Clavulanate Combination'}, {'id': 'D000077723', 'term': 'Cefepime'}, {'id': 'D010406', 'term': 'Penicillins'}, {'id': 'D000667', 'term': 'Ampicillin'}, {'id': 'D002981', 'term': 'Clindamycin'}, {'id': 'D010068', 'term': 'Oxacillin'}], 'ancestors': [{'id': 'D024841', 'term': 'Fluoroquinolones'}, {'id': 'D042462', 'term': '4-Quinolones'}, {'id': 'D015363', 'term': 'Quinolones'}, {'id': 'D011804', 'term': 'Quinolines'}, {'id': 'D006574', 'term': 'Heterocyclic Compounds, 2-Ring'}, {'id': 'D000072471', 'term': 'Heterocyclic Compounds, Fused-Ring'}, {'id': 'D006571', 'term': 'Heterocyclic Compounds'}, {'id': 'D013420', 'term': 'Sulfamethoxazole'}, {'id': 'D000096926', 'term': 'Benzenesulfonamides'}, {'id': 'D013449', 'term': 'Sulfonamides'}, {'id': 'D000577', 'term': 'Amides'}, {'id': 'D009930', 'term': 'Organic Chemicals'}, {'id': 'D013424', 'term': 'Sulfanilamides'}, {'id': 'D000814', 'term': 'Aniline Compounds'}, {'id': 'D000588', 'term': 'Amines'}, {'id': 'D001555', 'term': 'Benzene Derivatives'}, {'id': 'D006841', 'term': 'Hydrocarbons, Aromatic'}, {'id': 'D006844', 'term': 'Hydrocarbons, Cyclic'}, {'id': 'D006838', 'term': 'Hydrocarbons'}, {'id': 'D013450', 'term': 'Sulfones'}, {'id': 'D013457', 'term': 'Sulfur Compounds'}, {'id': 'D014295', 'term': 'Trimethoprim'}, {'id': 'D011743', 'term': 'Pyrimidines'}, {'id': 'D006573', 'term': 'Heterocyclic Compounds, 1-Ring'}, {'id': 'D004338', 'term': 'Drug Combinations'}, {'id': 'D004364', 'term': 'Pharmaceutical Preparations'}, {'id': 'D018942', 'term': 'Macrolides'}, {'id': 'D061065', 'term': 'Polyketides'}, {'id': 'D007783', 'term': 'Lactones'}, {'id': 'D011409', 'term': 'Propylene Glycols'}, {'id': 'D006018', 'term': 'Glycols'}, {'id': 'D000438', 'term': 'Alcohols'}, {'id': 'D009578', 'term': 'Nitrobenzenes'}, {'id': 'D009574', 'term': 'Nitro Compounds'}, {'id': 'D000617', 'term': 'Aminoglycosides'}, {'id': 'D006027', 'term': 'Glycosides'}, {'id': 'D002241', 'term': 'Carbohydrates'}, {'id': 'D013754', 'term': 'Tetracyclines'}, {'id': 'D009279', 'term': 'Naphthacenes'}, {'id': 'D011084', 'term': 'Polycyclic Aromatic Hydrocarbons'}, {'id': 'D011083', 'term': 'Polycyclic Compounds'}, {'id': 'D006020', 'term': 'Glycopeptides'}, {'id': 'D006001', 'term': 'Glycoconjugates'}, {'id': 'D010455', 'term': 'Peptides'}, {'id': 'D000602', 'term': 'Amino Acids, Peptides, and Proteins'}, {'id': 'D019818', 'term': 'Clavulanic Acid'}, {'id': 'D002969', 'term': 'Clavulanic Acids'}, {'id': 'D047090', 'term': 'beta-Lactams'}, {'id': 'D007769', 'term': 'Lactams'}, {'id': 'D000658', 'term': 'Amoxicillin'}, {'id': 'D010400', 'term': 'Penicillin G'}, {'id': 'D002511', 'term': 'Cephalosporins'}, {'id': 'D013843', 'term': 'Thiazines'}, {'id': 'D008034', 'term': 'Lincomycin'}, {'id': 'D055231', 'term': 'Lincosamides'}, {'id': 'D011759', 'term': 'Pyrrolidines'}]}}, 'protocolSection': {'designModule': {'studyType': 'OBSERVATIONAL', 'designInfo': {'timePerspective': 'PROSPECTIVE', 'observationalModel': 'CASE_CONTROL'}, 'enrollmentInfo': {'type': 'ACTUAL', 'count': 24}, 'patientRegistry': False}, 'statusModule': {'overallStatus': 'COMPLETED', 'startDateStruct': {'date': '2019-08-01', 'type': 'ACTUAL'}, 'expandedAccessInfo': {'hasExpandedAccess': False}, 'statusVerifiedDate': '2021-10', 'completionDateStruct': {'date': '2019-10-01', 'type': 'ACTUAL'}, 'lastUpdateSubmitDate': '2021-10-24', 'studyFirstSubmitDate': '2021-10-24', 'studyFirstSubmitQcDate': '2021-10-24', 'lastUpdatePostDateStruct': {'date': '2021-11-04', 'type': 'ACTUAL'}, 'studyFirstPostDateStruct': {'date': '2021-11-04', 'type': 'ACTUAL'}, 'primaryCompletionDateStruct': {'date': '2019-10-01', 'type': 'ACTUAL'}}, 'outcomesModule': {'primaryOutcomes': [{'measure': 'Positive culture', 'timeFrame': 'August 2019 to October 2019', 'description': 'Positive swab culture from the wound'}], 'secondaryOutcomes': [{'measure': 'Gram stain and type of Bacteria', 'timeFrame': 'August 2019 to October 2019', 'description': 'Gram stain and type of Bacteria grown in culture media'}, {'measure': 'Antibiotic Susceptibility', 'timeFrame': 'August 2019 to October 2019', 'description': 'Antibiotic Susceptibility to the isolated organisms'}]}, 'oversightModule': {'isUsExport': False, 'oversightHasDmc': False, 'isFdaRegulatedDrug': True, 'isFdaRegulatedDevice': False}, 'conditionsModule': {'keywords': ['antimicrobial', 'hospital', 'post-surgical infection', 'surgery'], 'conditions': ['Bacterial Infections', 'Antibiotic Resistant Infection', 'Surgical Site Infection']}, 'descriptionModule': {'briefSummary': 'The main aim of the study was to identify the various pathogens associated with surgical site infections and their antibiotic susceptibility in a governmental hospital in northern Jordan.', 'detailedDescription': 'Background: Surgical site infections are hospital-acquired, vary from one hospital to another, and can cause significant postoperative morbidity, mortality, and prolonged hospital stay.\n\nAim: The main aim of the study was to identify the various pathogens associated with surgical site infections and their antibiotic susceptibility in a governmental hospital in northern Jordan.\n\nMethods: Postsurgical wound samples were collected and processed in a microbiology laboratory using standard microbiological techniques. Antibiotic susceptibility tests were performed using 13 antibiotics covering the gram-positive and gram-negative bacteria using the disc diffusion test.'}, 'eligibilityModule': {'sex': 'ALL', 'stdAges': ['CHILD', 'ADULT', 'OLDER_ADULT'], 'samplingMethod': 'PROBABILITY_SAMPLE', 'studyPopulation': 'A hospital-based prospective study was carried out in Public-Teaching Hospital in northern Jordan with a total capacity of 400 beds, All patients meet the criteria of getting post-operative wound infections in different surgical wards and ICUs.', 'eligibilityCriteria': 'Inclusion Criteria:\n\n* Post-Surgical Wound Infection\n\nExclusion Criteria:\n\n\\-'}, 'identificationModule': {'nctId': 'NCT05106803', 'briefTitle': 'Antibiotic Profile of Pathogenic Bacteria Isolated in Public Hospitals in Northern Jordan', 'organization': {'class': 'OTHER', 'fullName': 'Yarmouk University'}, 'officialTitle': 'Antibiotic Profile of Pathogenic Bacteria Isolated From Postsurgical Site Infections in Public Hospitals in Northern Jordan', 'orgStudyIdInfo': {'id': 'Antibiotic profile in Jordan'}}, 'armsInterventionsModule': {'armGroups': [{'label': 'Wound infection', 'description': 'Patients with surgical site infection as diagnosed by the attending physician', 'interventionNames': ['Drug: ciprofloxacin']}], 'interventions': [{'name': 'ciprofloxacin', 'type': 'DRUG', 'otherNames': ['trimethoprim-sulfamethoxazole', 'norfloxacin', 'erythromycin', 'chloramphenicol', 'gentamicin', 'tetracycline', 'vancomycin', 'amoxicillin/clavulanic acid', 'cefepime', 'penicillin', 'ampicillin', 'clindamycin', 'oxacillin'], 'description': 'Antibiotics used in vitro n the study', 'armGroupLabels': ['Wound infection']}]}, 'contactsLocationsModule': {'locations': [{'zip': '21163', 'city': 'Irbid', 'country': 'Jordan', 'facility': 'Yarmouk University', 'geoPoint': {'lat': 32.55556, 'lon': 35.85}}], 'overallOfficials': [{'name': 'Raed M Ennab', 'role': 'PRINCIPAL_INVESTIGATOR', 'affiliation': 'Department of Clinical Sciences, Faculty Of Medicine, Yarmouk University'}]}, 'ipdSharingStatementModule': {'ipdSharing': 'NO'}, 'sponsorCollaboratorsModule': {'leadSponsor': {'name': 'Yarmouk University', 'class': 'OTHER'}, 'responsibleParty': {'type': 'PRINCIPAL_INVESTIGATOR', 'investigatorTitle': 'Assistant Professor', 'investigatorFullName': 'Raed M Ennab', 'investigatorAffiliation': 'Yarmouk University'}}}}