Ignite Creation Date:
2025-12-24 @ 7:22 PM
Ignite Modification Date:
2025-12-28 @ 5:49 PM
Study NCT ID:
NCT04705103
Status:
UNKNOWN
Last Update Posted:
2021-01-12
First Post:
2021-01-08
Is NOT Gene Therapy:
True
Has Adverse Events:
False
Brief Title:
Development of AI Model for Uveitis Progression and Prognosis
Sponsor:
Organization:
Raw JSON
{'hasResults': False, 'derivedSection': {'miscInfoModule': {'versionHolder': '2025-12-24'}, 'conditionBrowseModule': {'meshes': [{'id': 'D014605', 'term': 'Uveitis'}], 'ancestors': [{'id': 'D014603', 'term': 'Uveal Diseases'}, {'id': 'D005128', 'term': 'Eye Diseases'}]}}, 'protocolSection': {'designModule': {'studyType': 'OBSERVATIONAL', 'designInfo': {'timePerspective': 'PROSPECTIVE', 'observationalModel': 'COHORT'}, 'enrollmentInfo': {'type': 'ESTIMATED', 'count': 450}, 'targetDuration': '6 Months', 'patientRegistry': True}, 'statusModule': {'overallStatus': 'UNKNOWN', 'lastKnownStatus': 'NOT_YET_RECRUITING', 'startDateStruct': {'date': '2021-01-10', 'type': 'ESTIMATED'}, 'expandedAccessInfo': {'hasExpandedAccess': False}, 'statusVerifiedDate': '2021-01', 'completionDateStruct': {'date': '2022-12-30', 'type': 'ESTIMATED'}, 'lastUpdateSubmitDate': '2021-01-08', 'studyFirstSubmitDate': '2021-01-08', 'studyFirstSubmitQcDate': '2021-01-08', 'lastUpdatePostDateStruct': {'date': '2021-01-12', 'type': 'ACTUAL'}, 'studyFirstPostDateStruct': {'date': '2021-01-12', 'type': 'ACTUAL'}, 'primaryCompletionDateStruct': {'date': '2022-11-30', 'type': 'ESTIMATED'}}, 'outcomesModule': {'primaryOutcomes': [{'measure': 'uveitis progression', 'timeFrame': 'up to 1 month', 'description': 'uveitis progression is divided into remission, relapse, or initial'}]}, 'oversightModule': {'isFdaRegulatedDrug': False, 'isFdaRegulatedDevice': False}, 'conditionsModule': {'conditions': ['Uveitis']}, 'descriptionModule': {'briefSummary': 'Uveitis is a recurrent inflammation of the eye that can lead to vision loss with various and complicated etiologies. There are many difficulties in uveitis management due to the requirement of long-term monitoring and treatment. This study intends to establish a longitudinal cohort of uveitis patients to colloect multimodal clinical data including visual acuity, intraocular pressure, anterior segment photography, fundus photography, fluoroscopy and other ophthalmic examinations, and final diagnosis in order to use artificial intelligence and deep learning technology to extract ocular features, explore the association with the progression and prognosis of uveitis and finally establish a disease management model for uveitis.'}, 'eligibilityModule': {'sex': 'ALL', 'stdAges': ['CHILD', 'ADULT', 'OLDER_ADULT'], 'samplingMethod': 'PROBABILITY_SAMPLE', 'studyPopulation': '1. Initial stage of uveitis: The first episode of uveitis without treatment;\n2. Remission of uveitis: Uveitis caused by various reasons in the stable disease period of more than 3 months without treatment;\n3. Relapse of uveitis: After discontinuation of uveitis treatment, the disease stabilized for more than 3 months.', 'healthyVolunteers': False, 'eligibilityCriteria': 'Inclusion Criteria:\n\n* Participants who were diagnosed as uveitis, including the initial stage or relapse, or remission of uveitis.\n\nExclusion Criteria:\n\n* Participants who cannnot cooperate with ocualr examination.'}, 'identificationModule': {'nctId': 'NCT04705103', 'briefTitle': 'Development of AI Model for Uveitis Progression and Prognosis', 'organization': {'class': 'OTHER', 'fullName': 'Sun Yat-sen University'}, 'officialTitle': 'Development of Artificial Intelligence Prediction Model for Uveitis Progression and Prognosis', 'orgStudyIdInfo': {'id': '2020KYPJ185'}}, 'armsInterventionsModule': {'armGroups': [{'label': 'initial'}, {'label': 'relapse'}, {'label': 'inactive'}]}, 'contactsLocationsModule': {'centralContacts': [{'name': 'Haotian Lin, M.D.,Ph.D', 'role': 'CONTACT', 'email': 'gddlht@aliyun.com', 'phone': '13802793086'}, {'name': 'shuyi Zhang, M.D.', 'role': 'CONTACT', 'email': 'shuyi_z@163.com', 'phone': '15622177115'}]}, 'ipdSharingStatementModule': {'ipdSharing': 'UNDECIDED'}, 'sponsorCollaboratorsModule': {'leadSponsor': {'name': 'Sun Yat-sen University', 'class': 'OTHER'}, 'responsibleParty': {'type': 'PRINCIPAL_INVESTIGATOR', 'investigatorTitle': 'Professor', 'investigatorFullName': 'Haotian Lin', 'investigatorAffiliation': 'Sun Yat-sen University'}}}}