Ignite Creation Date:
2025-12-24 @ 7:19 PM
Ignite Modification Date:
2025-12-27 @ 8:10 AM
Study NCT ID:
NCT01113203
Status:
COMPLETED
Last Update Posted:
2010-04-29
First Post:
2010-04-27
Is NOT Gene Therapy:
True
Has Adverse Events:
False
Brief Title:
Chronic and Acute Effects of Resistance Exercise on Older Subjects' Blood Pressure
Sponsor:
Organization:
Raw JSON
{'hasResults': False, 'derivedSection': {'miscInfoModule': {'versionHolder': '2025-12-24'}, 'interventionBrowseModule': {'meshes': [{'id': 'D055070', 'term': 'Resistance Training'}], 'ancestors': [{'id': 'D005081', 'term': 'Exercise Therapy'}, {'id': 'D012046', 'term': 'Rehabilitation'}, {'id': 'D000359', 'term': 'Aftercare'}, {'id': 'D003266', 'term': 'Continuity of Patient Care'}, {'id': 'D005791', 'term': 'Patient Care'}, {'id': 'D013812', 'term': 'Therapeutics'}, {'id': 'D026741', 'term': 'Physical Therapy Modalities'}, {'id': 'D064797', 'term': 'Physical Conditioning, Human'}, {'id': 'D015444', 'term': 'Exercise'}, {'id': 'D009043', 'term': 'Motor Activity'}, {'id': 'D009068', 'term': 'Movement'}, {'id': 'D009142', 'term': 'Musculoskeletal Physiological Phenomena'}, {'id': 'D055687', 'term': 'Musculoskeletal and Neural Physiological Phenomena'}]}}, 'protocolSection': {'designModule': {'phases': ['NA'], 'studyType': 'INTERVENTIONAL', 'designInfo': {'allocation': 'RANDOMIZED', 'maskingInfo': {'masking': 'NONE'}, 'primaryPurpose': 'PREVENTION', 'interventionModel': 'PARALLEL'}, 'enrollmentInfo': {'type': 'ACTUAL', 'count': 25}}, 'statusModule': {'overallStatus': 'COMPLETED', 'startDateStruct': {'date': '2008-01'}, 'expandedAccessInfo': {'hasExpandedAccess': False}, 'statusVerifiedDate': '2010-04', 'completionDateStruct': {'date': '2008-12', 'type': 'ACTUAL'}, 'lastUpdateSubmitDate': '2010-04-28', 'studyFirstSubmitDate': '2010-04-27', 'studyFirstSubmitQcDate': '2010-04-28', 'lastUpdatePostDateStruct': {'date': '2010-04-29', 'type': 'ESTIMATED'}, 'studyFirstPostDateStruct': {'date': '2010-04-29', 'type': 'ESTIMATED'}, 'primaryCompletionDateStruct': {'date': '2008-12', 'type': 'ACTUAL'}}, 'outcomesModule': {'primaryOutcomes': [{'measure': 'blood pressure', 'timeFrame': '16 weeks', 'description': 'Blood pressure was measured by auscultatory, oscillometric and photoplethysmographic device'}], 'secondaryOutcomes': [{'measure': 'cardiovascular hemodynamics', 'timeFrame': '16 weeks', 'description': 'cardiac output (CO2 rebreathing technique)'}, {'measure': 'cardiovascular autonomic modulation', 'timeFrame': '16 weeks', 'description': 'Spectral analysis of heart rate and blood pressure variabillity'}]}, 'oversightModule': {'oversightHasDmc': False}, 'conditionsModule': {'keywords': ['resistance training', 'blood pressure', 'hemodynamics', 'autonomic', 'Elderly Subjects'], 'conditions': ['Blood Pressure']}, 'referencesModule': {'references': [{'pmid': '23175179', 'type': 'DERIVED', 'citation': 'Queiroz AC, Kanegusuku H, Chehuen MR, Costa LA, Wallerstein LF, Dias da Silva VJ, Mello MT, Ugrinowitsch C, Forjaz CL. Cardiac work remains high after strength exercise in elderly. Int J Sports Med. 2013 May;34(5):391-7. doi: 10.1055/s-0032-1323779. Epub 2012 Nov 22.'}]}, 'descriptionModule': {'briefSummary': 'The study aimed to evaluate the chronic and acute effects of high-intensity resistance training on blood pressure and its hemodynamic and neural determinators in healthy normotensive older subjects.', 'detailedDescription': 'To investigate the chronic and acute effects of resistance training on blood pressure and its hemodynamic and neural determinators in elderly, 24 healthy normotensive older subjects were randomly divided into 2 groups: trained and control. The trained group was submitted a progressive high-intensity resistance training. Before and after 16 weeks, as well as, before and after the one training session, blood pressure (clinic and ambulatory), cardiac output (CO2 rebreathing), and autonomic modulation (spectral analysis of heart rate and blood pressure variabilities) were measured'}, 'eligibilityModule': {'sex': 'ALL', 'stdAges': ['ADULT', 'OLDER_ADULT'], 'maximumAge': '80 Years', 'minimumAge': '60 Years', 'healthyVolunteers': True, 'eligibilityCriteria': 'Inclusion Criteria:\n\n* Age 60 to 80 years\n* Normotensives\n* Nonactive\n\nExclusion Criteria:\n\n* Cardiovascular disease\n* Cardiovascular medication\n* Orthopedic problems'}, 'identificationModule': {'nctId': 'NCT01113203', 'acronym': 'RTBP', 'briefTitle': "Chronic and Acute Effects of Resistance Exercise on Older Subjects' Blood Pressure", 'organization': {'class': 'OTHER', 'fullName': 'University of Sao Paulo'}, 'officialTitle': "Chronic and Acute Effects of Resistance Exercise on Older Subjects' Blood Pressure", 'orgStudyIdInfo': {'id': 'CNPq471600/2008-3'}}, 'armsInterventionsModule': {'armGroups': [{'type': 'EXPERIMENTAL', 'label': 'Resistance training', 'description': 'Progressive high intensity resistance training performed twice a week for 16 weeks, and achieving in 7 exercises for the main muscles, the protocol of 4 sets of 6RM and 2 of 4RM.', 'interventionNames': ['Behavioral: Resistance training']}], 'interventions': [{'name': 'Resistance training', 'type': 'BEHAVIORAL', 'otherNames': ['strength training, weight training'], 'description': 'Progressive high intensity resistance training performed twice a week for 16 weeks, and achieving in 7 exercises for the main muscles, the protocol of 4 sets of 6RM and 2 of 4RM.', 'armGroupLabels': ['Resistance training']}]}, 'contactsLocationsModule': {'locations': [{'zip': '05508-030', 'city': 'São Paulo', 'state': 'São Paulo', 'country': 'Brazil', 'facility': 'School of Physical Education and Sport, University of São Paulo', 'geoPoint': {'lat': -23.5475, 'lon': -46.63611}}], 'overallOfficials': [{'name': 'Claudia LM Forjaz, PhD', 'role': 'PRINCIPAL_INVESTIGATOR', 'affiliation': 'School of Physical Education and Sport, University of São Paulo'}]}, 'sponsorCollaboratorsModule': {'leadSponsor': {'name': 'University of Sao Paulo', 'class': 'OTHER'}, 'collaborators': [{'name': 'Conselho Nacional de Desenvolvimento Científico e Tecnológico', 'class': 'OTHER_GOV'}, {'name': 'Fundação de Amparo à Pesquisa do Estado de São Paulo', 'class': 'OTHER_GOV'}, {'name': 'Coordenação de Aperfeiçoamento de Pessoal de Nível Superior.', 'class': 'OTHER_GOV'}, {'name': 'Associacao Fundo de Incentivo a Psicofarmcologia', 'class': 'OTHER'}, {'name': 'Federal University of São Paulo', 'class': 'OTHER'}, {'name': 'Delboni Auriemo', 'class': 'UNKNOWN'}], 'responsibleParty': {'oldNameTitle': 'Cláudia Lúcia de Moraes Forjaz', 'oldOrganization': 'School of Physical Education, University of São Paulo'}}}}