Ignite Creation Date:
2025-12-24 @ 7:02 PM
Ignite Modification Date:
2025-12-25 @ 4:36 PM
Study NCT ID:
NCT07221357
Status:
RECRUITING
Last Update Posted:
2025-12-18
First Post:
2025-10-23
Is NOT Gene Therapy:
False
Has Adverse Events:
False
Brief Title:
A Study to Evaluate the Safety and Efficacy of Pumitamig in Combination With Chemotherapy Versus Bevacizumab in Combination With Chemotherapy in Participants With Previously Untreated, Unresectable, or Metastatic Colorectal Cancer
Sponsor:
Organization:
Raw JSON
{'hasResults': False, 'derivedSection': {'miscInfoModule': {'versionHolder': '2025-12-24'}, 'conditionBrowseModule': {'meshes': [{'id': 'D015179', 'term': 'Colorectal Neoplasms'}], 'ancestors': [{'id': 'D007414', 'term': 'Intestinal Neoplasms'}, {'id': 'D005770', 'term': 'Gastrointestinal Neoplasms'}, {'id': 'D004067', 'term': 'Digestive System Neoplasms'}, {'id': 'D009371', 'term': 'Neoplasms by Site'}, {'id': 'D009369', 'term': 'Neoplasms'}, {'id': 'D004066', 'term': 'Digestive System Diseases'}, {'id': 'D005767', 'term': 'Gastrointestinal Diseases'}, {'id': 'D003108', 'term': 'Colonic Diseases'}, {'id': 'D007410', 'term': 'Intestinal Diseases'}, {'id': 'D012002', 'term': 'Rectal Diseases'}]}, 'interventionBrowseModule': {'meshes': [{'id': 'C410216', 'term': 'Folfox protocol'}, {'id': 'C480833', 'term': 'IFL protocol'}, {'id': 'D000068258', 'term': 'Bevacizumab'}], 'ancestors': [{'id': 'D061067', 'term': 'Antibodies, Monoclonal, Humanized'}, {'id': 'D000911', 'term': 'Antibodies, Monoclonal'}, {'id': 'D000906', 'term': 'Antibodies'}, {'id': 'D007136', 'term': 'Immunoglobulins'}, {'id': 'D007162', 'term': 'Immunoproteins'}, {'id': 'D001798', 'term': 'Blood Proteins'}, {'id': 'D011506', 'term': 'Proteins'}, {'id': 'D000602', 'term': 'Amino Acids, Peptides, and Proteins'}, {'id': 'D012712', 'term': 'Serum Globulins'}, {'id': 'D005916', 'term': 'Globulins'}]}}, 'protocolSection': {'designModule': {'phases': ['PHASE2', 'PHASE3'], 'studyType': 'INTERVENTIONAL', 'designInfo': {'allocation': 'RANDOMIZED', 'maskingInfo': {'masking': 'DOUBLE', 'whoMasked': ['PARTICIPANT', 'INVESTIGATOR']}, 'primaryPurpose': 'TREATMENT', 'interventionModel': 'PARALLEL'}, 'enrollmentInfo': {'type': 'ESTIMATED', 'count': 990}}, 'statusModule': {'overallStatus': 'RECRUITING', 'startDateStruct': {'date': '2026-03-04', 'type': 'ESTIMATED'}, 'expandedAccessInfo': {'hasExpandedAccess': False}, 'statusVerifiedDate': '2025-12', 'completionDateStruct': {'date': '2034-03-11', 'type': 'ESTIMATED'}, 'lastUpdateSubmitDate': '2025-12-17', 'studyFirstSubmitDate': '2025-10-23', 'studyFirstSubmitQcDate': '2025-10-23', 'lastUpdatePostDateStruct': {'date': '2025-12-18', 'type': 'ESTIMATED'}, 'studyFirstPostDateStruct': {'date': '2025-10-27', 'type': 'ESTIMATED'}, 'primaryCompletionDateStruct': {'date': '2030-02-02', 'type': 'ESTIMATED'}}, 'outcomesModule': {'primaryOutcomes': [{'measure': 'Objective Response (OR) (confirmed complete response (CR) or partial response (PR)) by Response Evaluation Criteria in Solid Tumors (RECIST) v1.1 per investigator assessment', 'timeFrame': 'Up to 5 years', 'description': 'Phase 2'}, {'measure': 'Progression Free Survival (PFS) by RECIST v1.1 per blinded independent central review (BICR)', 'timeFrame': 'Up to 5 years', 'description': 'Phase 3'}], 'secondaryOutcomes': [{'measure': 'PFS by RECIST v1.1 per investigator assessment', 'timeFrame': 'Up to 5 years', 'description': 'Phase 2'}, {'measure': 'Duration of Response (DOR) (CR or PR) by RECIST v1.1 per investigator assessment', 'timeFrame': 'Up to 5 years', 'description': 'Phase 2'}, {'measure': 'Time to Response (TTR) (CR or PR) by RECIST v1.1 per investigator assessment', 'timeFrame': 'Up to 5 years', 'description': 'Phase 2'}, {'measure': 'Disease control (Best Overall Response (BOR) of confirmed CR, confirmed PR, or Stable Disease (SD)) by RECIST v1.1 per investigator assessment', 'timeFrame': 'Up to 5 years', 'description': 'Phase 2'}, {'measure': 'Recommended dose of Pumitamig for Phase 3', 'timeFrame': 'Up to 5 years', 'description': 'Phase 2'}, {'measure': 'Overall Survival (OS)', 'timeFrame': 'Up to 5 years', 'description': 'Phase 3'}, {'measure': 'OR by RECIST v1.1 per BICR', 'timeFrame': 'Up to 5 years', 'description': 'Phase 3'}, {'measure': 'DOR by RECIST v1.1 per BICR', 'timeFrame': 'Up to 5 years', 'description': 'Phase 3'}]}, 'oversightModule': {'oversightHasDmc': True, 'isFdaRegulatedDrug': True, 'isFdaRegulatedDevice': False}, 'conditionsModule': {'keywords': ['Metastatic Colorectal Cancer (mCRC)'], 'conditions': ['Untreated, Unresectable, or Metastatic Colorectal Cancer']}, 'referencesModule': {'seeAlsoLinks': [{'url': 'https://www.bms.com/researchers-and-partners/clinical-trials-and-research.html', 'label': 'BMS Clinical Trial Information'}, {'url': 'https://www.bmsclinicaltrials.com/us/en/clinical-trials/NCT07221357.html', 'label': 'BMS Clinical Trial Patient Recruiting'}]}, 'descriptionModule': {'briefSummary': 'The purpose of this study is to evaluate the safety and efficacy of pumitamig in combination with chemotherapy versus bevacizumab in combination with chemotherapy in participants with previously untreated, unresectable, or metastatic colorectal cancer'}, 'eligibilityModule': {'sex': 'ALL', 'stdAges': ['ADULT', 'OLDER_ADULT'], 'minimumAge': '18 Years', 'healthyVolunteers': False, 'eligibilityCriteria': 'Inclusion Criteria\n\n* Participant must previously untreated, histologically confirmed recurrent or metastatic colorectal adenocarcinoma, not amenable to curative surgery.\n* Participant must have no known presence of mismatch repair deficient (dMMR) or microsatellite instability-high (MSI-H) colorectal cancer (CRC) per historical results (a validated test should be used).\n* Participant must have no known presence of the gene that encodes the protein B-Raf (BRAF) V600E mutation per local testing.\n* Participant must have measurable disease as defined by Response Evaluation Criteria in Solid Tumors (RECIST) v1.1.\n\nExclusion Criteria\n\n* Participant must not have any untreated known central nervous system (CNS) metastases including brain, leptomeningeal and/or spinal cord compression.\n* Participant must not have any prior malignancy active within the previous 2 years, except for locally curable cancers that have been apparently cured and considered to be of low risk of recurrence.\n* Participant must not have significant cardiovascular disease, such as myocardial infarction, unstable angina, arterial thrombosis or cerebrovascular accident within 6 months prior to randomization, uncontrolled hypertension (≥ 160 systolic, ≥ 100 diastolic mm Hg) despite optimal medical management, or congenital long QT syndrome.\n* Participant must not have prior systemic treatment with an anti-PD-1, anti-programmed death (ligand)-1 (PD-L1), anti-PD-L2, CD137 agonists, or anti-cytotoxic T-lymphocyte associated protein 4 (CTLA-4) antibody, or any other antibody or drug specifically targeting T cell co-stimulation or checkpoint pathways or chemotherapy.\n* Other protocol-defined Inclusion/Exclusion criteria apply.'}, 'identificationModule': {'nctId': 'NCT07221357', 'briefTitle': 'A Study to Evaluate the Safety and Efficacy of Pumitamig in Combination With Chemotherapy Versus Bevacizumab in Combination With Chemotherapy in Participants With Previously Untreated, Unresectable, or Metastatic Colorectal Cancer', 'organization': {'class': 'INDUSTRY', 'fullName': 'Bristol-Myers Squibb'}, 'officialTitle': 'ROSETTA CRC-203: A Blinded, Randomized Phase 2/3 Study of Pumitamig in Combination With Chemotherapy Versus Bevacizumab in Combination With Chemotherapy in Participants With Previously Untreated, Unresectable, or Metastatic Colorectal Cancer', 'orgStudyIdInfo': {'id': 'CA266-0003'}, 'secondaryIdInfos': [{'id': '2025-523224-45', 'type': 'OTHER', 'domain': 'EU CT Number'}, {'id': 'U1111-1325-6505', 'type': 'OTHER', 'domain': 'UTN'}]}, 'armsInterventionsModule': {'armGroups': [{'type': 'EXPERIMENTAL', 'label': 'Arm A1', 'interventionNames': ['Drug: Pumitamig', 'Drug: FOLFOX', 'Drug: FOLFIRI']}, {'type': 'EXPERIMENTAL', 'label': 'Arm A2', 'interventionNames': ['Drug: Pumitamig', 'Drug: FOLFOX', 'Drug: FOLFIRI']}, {'type': 'OTHER', 'label': 'Arm B', 'interventionNames': ['Drug: FOLFOX', 'Drug: FOLFIRI', 'Drug: Bevacizumab']}, {'type': 'EXPERIMENTAL', 'label': 'Arm C', 'interventionNames': ['Drug: Pumitamig', 'Drug: FOLFOX', 'Drug: FOLFIRI', 'Drug: CAPOX']}, {'type': 'OTHER', 'label': 'Arm D', 'interventionNames': ['Drug: FOLFOX', 'Drug: FOLFIRI', 'Drug: Bevacizumab', 'Drug: CAPOX']}], 'interventions': [{'name': 'Pumitamig', 'type': 'DRUG', 'otherNames': ['BMS-986545', 'BNT327', 'PM8002'], 'description': 'Specified dose on specified days', 'armGroupLabels': ['Arm A1', 'Arm A2', 'Arm C']}, {'name': 'FOLFOX', 'type': 'DRUG', 'description': 'Specified dose on specified days', 'armGroupLabels': ['Arm A1', 'Arm A2', 'Arm B', 'Arm C', 'Arm D']}, {'name': 'FOLFIRI', 'type': 'DRUG', 'description': 'Specified dose on specified days', 'armGroupLabels': ['Arm A1', 'Arm A2', 'Arm B', 'Arm C', 'Arm D']}, {'name': 'Bevacizumab', 'type': 'DRUG', 'description': 'Specified dose on specified days', 'armGroupLabels': ['Arm B', 'Arm D']}, {'name': 'CAPOX', 'type': 'DRUG', 'description': 'Specified dose on specified days', 'armGroupLabels': ['Arm C', 'Arm D']}]}, 'contactsLocationsModule': {'locations': [{'zip': '90033', 'city': 'Los Angeles', 'state': 'California', 'status': 'NOT_YET_RECRUITING', 'country': 'United States', 'contacts': [{'name': 'Site 0263', 'role': 'CONTACT'}], 'facility': 'Local Institution - 0263', 'geoPoint': {'lat': 34.05223, 'lon': -118.24368}}, {'zip': '92868', 'city': 'Orange', 'state': 'California', 'status': 'NOT_YET_RECRUITING', 'country': 'United States', 'contacts': [{'name': 'Site 0345', 'role': 'CONTACT'}], 'facility': 'Local Institution - 0345', 'geoPoint': {'lat': 33.78779, 'lon': -117.85311}}, {'zip': '95816', 'city': 'Sacramento', 'state': 'California', 'status': 'NOT_YET_RECRUITING', 'country': 'United States', 'contacts': [{'name': 'Site 0317', 'role': 'CONTACT'}], 'facility': 'Local Institution - 0317', 'geoPoint': {'lat': 38.58157, 'lon': -121.4944}}, {'zip': '90404', 'city': 'Santa Monica', 'state': 'California', 'status': 'NOT_YET_RECRUITING', 'country': 'United States', 'contacts': [{'name': 'Site 0330', 'role': 'CONTACT'}], 'facility': 'Local Institution - 0330', 'geoPoint': {'lat': 34.01949, 'lon': -118.49138}}, {'zip': '94305', 'city': 'Stanford', 'state': 'California', 'status': 'NOT_YET_RECRUITING', 'country': 'United States', 'contacts': [{'name': 'Site 0293', 'role': 'CONTACT'}], 'facility': 'Local Institution - 0293', 'geoPoint': {'lat': 37.42411, 'lon': -122.16608}}, {'zip': '33990', 'city': 'Cape Coral', 'state': 'Florida', 'status': 'NOT_YET_RECRUITING', 'country': 'United States', 'contacts': [{'name': 'Site 0574', 'role': 'CONTACT'}], 'facility': 'Local Institution - 0574', 'geoPoint': {'lat': 26.56285, 'lon': -81.94953}}, {'zip': '33705', 'city': 'St. Petersburg', 'state': 'Florida', 'status': 'NOT_YET_RECRUITING', 'country': 'United States', 'contacts': [{'name': 'Site 0575', 'role': 'CONTACT'}], 'facility': 'Local Institution - 0575', 'geoPoint': {'lat': 27.77086, 'lon': -82.67927}}, {'zip': '33612', 'city': 'Tampa', 'state': 'Florida', 'status': 'NOT_YET_RECRUITING', 'country': 'United States', 'contacts': [{'name': 'Site 0269', 'role': 'CONTACT'}], 'facility': 'Local Institution - 0269', 'geoPoint': {'lat': 27.94752, 'lon': -82.45843}}, {'zip': '30096', 'city': 'Duluth', 'state': 'Georgia', 'status': 'NOT_YET_RECRUITING', 'country': 'United States', 'contacts': [{'name': 'Site 0276', 'role': 'CONTACT'}], 'facility': 'Local Institution - 0276', 'geoPoint': {'lat': 34.00288, 'lon': -84.14464}}, {'zip': '30060', 'city': 'Marietta', 'state': 'Georgia', 'status': 'NOT_YET_RECRUITING', 'country': 'United States', 'contacts': [{'name': 'Site 0369', 'role': 'CONTACT'}], 'facility': 'Local Institution - 0369', 'geoPoint': {'lat': 33.9526, 'lon': -84.54993}}, {'zip': '60637', 'city': 'Chicago', 'state': 'Illinois', 'status': 'NOT_YET_RECRUITING', 'country': 'United States', 'contacts': [{'name': 'Site 0433', 'role': 'CONTACT'}], 'facility': 'Local Institution - 0433', 'geoPoint': {'lat': 41.85003, 'lon': -87.65005}}, {'zip': '52242', 'city': 'Iowa City', 'state': 'Iowa', 'status': 'NOT_YET_RECRUITING', 'country': 'United States', 'contacts': [{'name': 'Site 0335', 'role': 'CONTACT'}], 'facility': 'Local Institution - 0335', 'geoPoint': {'lat': 41.66113, 'lon': -91.53017}}, {'zip': '21287', 'city': 'Baltimore', 'state': 'Maryland', 'status': 'NOT_YET_RECRUITING', 'country': 'United States', 'contacts': [{'name': 'Site 0262', 'role': 'CONTACT'}], 'facility': 'Local Institution - 0262', 'geoPoint': {'lat': 39.29038, 'lon': -76.61219}}, {'zip': '20904', 'city': 'Silver Spring', 'state': 'Maryland', 'status': 'NOT_YET_RECRUITING', 'country': 'United States', 'contacts': [{'name': 'Site 0580', 'role': 'CONTACT'}], 'facility': 'Local Institution - 0580', 'geoPoint': {'lat': 38.99067, 'lon': -77.02609}}, {'zip': '02114', 'city': 'Boston', 'state': 'Massachusetts', 'status': 'NOT_YET_RECRUITING', 'country': 'United States', 'contacts': [{'name': 'Site 0471', 'role': 'CONTACT'}], 'facility': 'Local Institution - 0471', 'geoPoint': {'lat': 42.35843, 'lon': -71.05977}}, {'zip': '48109', 'city': 'Ann Arbor', 'state': 'Michigan', 'status': 'NOT_YET_RECRUITING', 'country': 'United States', 'contacts': [{'name': 'Site 0430', 'role': 'CONTACT'}], 'facility': 'Local Institution - 0430', 'geoPoint': {'lat': 42.27756, 'lon': -83.74088}}, {'zip': '49546', 'city': 'Grand Rapids', 'state': 'Michigan', 'status': 'NOT_YET_RECRUITING', 'country': 'United States', 'contacts': [{'name': 'Site 0254', 'role': 'CONTACT'}], 'facility': 'Local Institution - 0254', 'geoPoint': {'lat': 42.96336, 'lon': -85.66809}}, {'zip': '55369', 'city': 'Maple Grove', 'state': 'Minnesota', 'status': 'NOT_YET_RECRUITING', 'country': 'United States', 'contacts': [{'name': 'Site 0572', 'role': 'CONTACT'}], 'facility': 'Local Institution - 0572', 'geoPoint': {'lat': 45.07246, 'lon': -93.45579}}, {'zip': '63110', 'city': 'St Louis', 'state': 'Missouri', 'status': 'NOT_YET_RECRUITING', 'country': 'United States', 'contacts': [{'name': 'Site 0336', 'role': 'CONTACT'}], 'facility': 'Local Institution - 0336', 'geoPoint': {'lat': 38.62727, 'lon': -90.19789}}, {'zip': '68198', 'city': 'Omaha', 'state': 'Nebraska', 'status': 'NOT_YET_RECRUITING', 'country': 'United States', 'contacts': [{'name': 'Site 0334', 'role': 'CONTACT'}], 'facility': 'Local Institution - 0334', 'geoPoint': {'lat': 41.25626, 'lon': -95.94043}}, {'zip': '14263', 'city': 'Buffalo', 'state': 'New York', 'status': 'NOT_YET_RECRUITING', 'country': 'United States', 'contacts': [{'name': 'Site 0302', 'role': 'CONTACT'}], 'facility': 'Local Institution - 0302', 'geoPoint': {'lat': 42.88645, 'lon': -78.87837}}, {'zip': '11042', 'city': 'Lake Success', 'state': 'New York', 'status': 'NOT_YET_RECRUITING', 'country': 'United States', 'contacts': [{'name': 'Site 0429', 'role': 'CONTACT'}], 'facility': 'Local Institution - 0429', 'geoPoint': {'lat': 40.77066, 'lon': -73.71763}}, {'zip': '11501-389', 'city': 'Mineola', 'state': 'New York', 'status': 'NOT_YET_RECRUITING', 'country': 'United States', 'contacts': [{'name': 'Site 0270', 'role': 'CONTACT'}], 'facility': 'Local Institution - 0270', 'geoPoint': {'lat': 40.74927, 'lon': -73.64068}}, {'zip': '43210', 'city': 'Columbus', 'state': 'Ohio', 'status': 'NOT_YET_RECRUITING', 'country': 'United States', 'contacts': [{'name': 'Site 0339', 'role': 'CONTACT'}], 'facility': 'Local Institution - 0339', 'geoPoint': {'lat': 39.96118, 'lon': -82.99879}}, {'zip': '97239', 'city': 'Portland', 'state': 'Oregon', 'status': 'NOT_YET_RECRUITING', 'country': 'United States', 'contacts': [{'name': 'Site 0308', 'role': 'CONTACT'}], 'facility': 'Local Institution - 0308', 'geoPoint': {'lat': 45.52345, 'lon': -122.67621}}, {'zip': '18103', 'city': 'Allentown', 'state': 'Pennsylvania', 'status': 'NOT_YET_RECRUITING', 'country': 'United States', 'contacts': [{'name': 'Site 0348', 'role': 'CONTACT'}], 'facility': 'Local Institution - 0348', 'geoPoint': {'lat': 40.60843, 'lon': -75.49018}}, {'zip': '15212', 'city': 'Pittsburgh', 'state': 'Pennsylvania', 'status': 'NOT_YET_RECRUITING', 'country': 'United States', 'contacts': [{'name': 'Site 0294', 'role': 'CONTACT'}], 'facility': 'Local Institution - 0294', 'geoPoint': {'lat': 40.44062, 'lon': -79.99589}}, {'zip': '57104', 'city': 'Sioux Falls', 'state': 'South Dakota', 'status': 'NOT_YET_RECRUITING', 'country': 'United States', 'contacts': [{'name': 'Site 0312', 'role': 'CONTACT'}], 'facility': 'Local Institution - 0312', 'geoPoint': {'lat': 43.54369, 'lon': -96.72796}}, {'zip': '37203', 'city': 'Nashville', 'state': 'Tennessee', 'status': 'NOT_YET_RECRUITING', 'country': 'United States', 'contacts': [{'name': 'Site 0333', 'role': 'CONTACT'}], 'facility': 'Local Institution - 0333', 'geoPoint': {'lat': 36.16589, 'lon': -86.78444}}, {'zip': '37203', 'city': 'Nashville', 'state': 'Tennessee', 'status': 'NOT_YET_RECRUITING', 'country': 'United States', 'contacts': [{'name': 'Site 0570', 'role': 'CONTACT'}], 'facility': 'Local Institution - 0570', 'geoPoint': {'lat': 36.16589, 'lon': -86.78444}}, {'zip': '76012', 'city': 'Arlington', 'state': 'Texas', 'status': 'RECRUITING', 'country': 'United States', 'contacts': [{'name': 'Laith Abushahin, Site 0573', 'role': 'CONTACT'}], 'facility': 'Texas Oncology Dallas Fort Worth West (DFWW) - Arlington Cancer Center North', 'geoPoint': {'lat': 32.73569, 'lon': -97.10807}}, {'zip': '78705', 'city': 'Austin', 'state': 'Texas', 'status': 'RECRUITING', 'country': 'United States', 'contacts': [{'name': 'Vivian Cline, Site 0571', 'role': 'CONTACT', 'phone': '512-427-9400'}], 'facility': 'Texas Oncology, PA', 'geoPoint': {'lat': 30.26715, 'lon': -97.74306}}, {'zip': '77030', 'city': 'Houston', 'state': 'Texas', 'status': 'NOT_YET_RECRUITING', 'country': 'United States', 'contacts': [{'name': 'Site 0252', 'role': 'CONTACT'}], 'facility': 'Local Institution - 0252', 'geoPoint': {'lat': 29.76328, 'lon': -95.36327}}, {'zip': '75702', 'city': 'Longview', 'state': 'Texas', 'status': 'NOT_YET_RECRUITING', 'country': 'United States', 'contacts': [{'name': 'Site 0576', 'role': 'CONTACT'}], 'facility': 'Local Institution - 0576', 'geoPoint': {'lat': 32.5007, 'lon': -94.74049}}, {'zip': '84102', 'city': 'Salt Lake City', 'state': 'Utah', 'status': 'NOT_YET_RECRUITING', 'country': 'United States', 'contacts': [{'name': 'Site 0426', 'role': 'CONTACT'}], 'facility': 'Local Institution - 0426', 'geoPoint': {'lat': 40.76078, 'lon': -111.89105}}, {'zip': '22031', 'city': 'Fairfax', 'state': 'Virginia', 'status': 'NOT_YET_RECRUITING', 'country': 'United States', 'contacts': [{'name': 'Site 0278', 'role': 'CONTACT'}], 'facility': 'Local Institution - 0278', 'geoPoint': {'lat': 38.84622, 'lon': -77.30637}}, {'zip': '23502', 'city': 'Norfolk', 'state': 'Virginia', 'status': 'NOT_YET_RECRUITING', 'country': 'United States', 'contacts': [{'name': 'Site 0577', 'role': 'CONTACT'}], 'facility': 'Local Institution - 0577', 'geoPoint': {'lat': 36.84681, 'lon': -76.28522}}, {'zip': '98026-8032', 'city': 'Edmonds', 'state': 'Washington', 'status': 'NOT_YET_RECRUITING', 'country': 'United States', 'contacts': [{'name': 'Site 0491', 'role': 'CONTACT'}], 'facility': 'Local Institution - 0491', 'geoPoint': {'lat': 47.81065, 'lon': -122.37736}}, {'zip': '98109', 'city': 'Seattle', 'state': 'Washington', 'status': 'NOT_YET_RECRUITING', 'country': 'United States', 'contacts': [{'name': 'Site 0253', 'role': 'CONTACT'}], 'facility': 'Local Institution - 0253', 'geoPoint': {'lat': 47.60621, 'lon': -122.33207}}, {'zip': '98684', 'city': 'Vancouver', 'state': 'Washington', 'status': 'NOT_YET_RECRUITING', 'country': 'United States', 'contacts': [{'name': 'Site 0578', 'role': 'CONTACT'}], 'facility': 'Local Institution - 0578', 'geoPoint': {'lat': 45.63873, 'lon': -122.66149}}, {'zip': 'C1199ABB', 'city': 'ABB', 'state': 'Buenos Aires F.D.', 'status': 'NOT_YET_RECRUITING', 'country': 'Argentina', 'contacts': [{'name': 'Site 0071', 'role': 'CONTACT'}], 'facility': 'Local Institution - 0071'}, {'zip': '1039', 'city': 'Buenos Aires', 'status': 'NOT_YET_RECRUITING', 'country': 'Argentina', 'contacts': [{'name': 'Site 0174', 'role': 'CONTACT'}], 'facility': 'Local Institution - 0174', 'geoPoint': {'lat': -34.61315, 'lon': -58.37723}}, {'zip': 'C1280AEB', 'city': 'Buenos Aires', 'status': 'NOT_YET_RECRUITING', 'country': 'Argentina', 'contacts': [{'name': 'Site 0073', 'role': 'CONTACT'}], 'facility': 'Local Institution - 0073', 'geoPoint': {'lat': -34.61315, 'lon': -58.37723}}, {'zip': 'C1426ANZ', 'city': 'Buenos Aires', 'status': 'NOT_YET_RECRUITING', 'country': 'Argentina', 'contacts': [{'name': 'Site 0069', 'role': 'CONTACT'}], 'facility': 'Local Institution - 0069', 'geoPoint': {'lat': -34.61315, 'lon': -58.37723}}, {'zip': 'C1431FWO', 'city': 'Buenos Aires', 'status': 'NOT_YET_RECRUITING', 'country': 'Argentina', 'contacts': [{'name': 'Site 0172', 'role': 'CONTACT'}], 'facility': 'Local Institution - 0172', 'geoPoint': {'lat': -34.61315, 'lon': -58.37723}}, {'zip': '2170', 'city': 'Liverpool', 'state': 'New South Wales', 'status': 'NOT_YET_RECRUITING', 'country': 'Australia', 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