Ignite Creation Date:
2025-12-24 @ 12:47 PM
Ignite Modification Date:
2025-12-27 @ 9:36 PM
Study NCT ID:
NCT02741661
Status:
COMPLETED
Last Update Posted:
2016-09-27
First Post:
2016-04-13
Is Gene Therapy:
True
Has Adverse Events:
False
Brief Title:
Influence of Myocardial Shortening on Coronary Tortuosity
Sponsor:
Organization:
Raw JSON
{'hasResults': False, 'derivedSection': {'miscInfoModule': {'versionHolder': '2025-12-24'}, 'conditionBrowseModule': {'meshes': [{'id': 'D003324', 'term': 'Coronary Artery Disease'}], 'ancestors': [{'id': 'D003327', 'term': 'Coronary Disease'}, {'id': 'D017202', 'term': 'Myocardial Ischemia'}, {'id': 'D006331', 'term': 'Heart Diseases'}, {'id': 'D002318', 'term': 'Cardiovascular Diseases'}, {'id': 'D001161', 'term': 'Arteriosclerosis'}, {'id': 'D001157', 'term': 'Arterial Occlusive Diseases'}, {'id': 'D014652', 'term': 'Vascular Diseases'}]}}, 'protocolSection': {'designModule': {'studyType': 'OBSERVATIONAL', 'designInfo': {'timePerspective': 'RETROSPECTIVE', 'observationalModel': 'CASE_CONTROL'}, 'enrollmentInfo': {'type': 'ACTUAL', 'count': 70}, 'patientRegistry': False}, 'statusModule': {'overallStatus': 'COMPLETED', 'startDateStruct': {'date': '2015-07'}, 'expandedAccessInfo': {'hasExpandedAccess': False}, 'statusVerifiedDate': '2016-09', 'completionDateStruct': {'date': '2016-09', 'type': 'ACTUAL'}, 'lastUpdateSubmitDate': '2016-09-26', 'studyFirstSubmitDate': '2016-04-13', 'studyFirstSubmitQcDate': '2016-04-15', 'lastUpdatePostDateStruct': {'date': '2016-09-27', 'type': 'ESTIMATED'}, 'studyFirstPostDateStruct': {'date': '2016-04-18', 'type': 'ESTIMATED'}, 'primaryCompletionDateStruct': {'date': '2016-09', 'type': 'ACTUAL'}}, 'outcomesModule': {'primaryOutcomes': [{'measure': 'Degree of longitudinal shortening', 'timeFrame': '3 months', 'description': 'Measurement of longitudinal shortening of the left ventricle measured on an echocardiography (retrospectively) that was performed within 3 months of the angiogram'}], 'secondaryOutcomes': [{'measure': 'LV mass', 'timeFrame': '3 months', 'description': 'Measurement of longitudinal shortening of the left ventricle measured on an echocardiography (retrospectively) that was performed within 3 months of the angiogram'}]}, 'oversightModule': {'oversightHasDmc': False}, 'conditionsModule': {'conditions': ['Coronary Artery Vessels', 'Coronary Artery Disease']}, 'descriptionModule': {'briefSummary': 'This study is a retrospective analysis where coronary arteriograms are being analyzed to determine whether the presence of tortuous coronary arteries correlate with any specific measures of left ventricular mass or left ventricular function on echocardiography.'}, 'eligibilityModule': {'sex': 'ALL', 'stdAges': ['ADULT', 'OLDER_ADULT'], 'maximumAge': '90 Years', 'minimumAge': '19 Years', 'samplingMethod': 'NON_PROBABILITY_SAMPLE', 'studyPopulation': 'Retrospective study of subjects who have undergone clinically-indicated coronary arteriography who also have an echocardiogram that was performed within 3 months of the angiogram.', 'healthyVolunteers': False, 'eligibilityCriteria': 'Inclusion Criteria:\n\n* subjects referred for angiography\n* echocardiography performed within 3 months.\n\nExclusion Criteria:\n\n* connective tissue disease\n* severe LV dysfunction\n* prior coronary artery bypass surgery\n* major adverse coronary event between angiogram and echo procedures\n* moderate or greater valve disease\n* acute coronary syndrome'}, 'identificationModule': {'nctId': 'NCT02741661', 'briefTitle': 'Influence of Myocardial Shortening on Coronary Tortuosity', 'organization': {'class': 'OTHER', 'fullName': 'Oregon Health and Science University'}, 'officialTitle': 'Determinants of Coronary Tortuosity', 'orgStudyIdInfo': {'id': 'Coronary Tortuosity'}}, 'armsInterventionsModule': {'armGroups': [{'label': 'Normal coronary arteries', 'description': 'Patients in whom coronary arteriography has demonstrated no significant tortuosity.', 'interventionNames': ['Other: No intervention. Observational study']}, {'label': 'Tortuous coronary arteries', 'description': 'Patients in whom coronary arteriography has demonstrated tortuous coronary arteries defined as \\>1 major bend of \\>45 degrees in a major coronary artery', 'interventionNames': ['Other: No intervention. Observational study']}], 'interventions': [{'name': 'No intervention. Observational study', 'type': 'OTHER', 'description': 'No intervention', 'armGroupLabels': ['Normal coronary arteries', 'Tortuous coronary arteries']}]}, 'contactsLocationsModule': {'locations': [{'zip': '97239', 'city': 'Portland', 'state': 'Oregon', 'country': 'United States', 'facility': 'OHSU', 'geoPoint': {'lat': 45.52345, 'lon': -122.67621}}]}, 'ipdSharingStatementModule': {'ipdSharing': 'YES'}, 'sponsorCollaboratorsModule': {'leadSponsor': {'name': 'Oregon Health and Science University', 'class': 'OTHER'}, 'responsibleParty': {'type': 'PRINCIPAL_INVESTIGATOR', 'investigatorTitle': 'Professor', 'investigatorFullName': 'Jonathan R. Lindner, MD', 'investigatorAffiliation': 'Oregon Health and Science University'}}}}