Ignite Creation Date:
2025-12-24 @ 6:45 PM
Ignite Modification Date:
2025-12-29 @ 2:46 PM
Study NCT ID:
NCT02763657
Status:
UNKNOWN
Last Update Posted:
2016-05-05
First Post:
2016-05-03
Is NOT Gene Therapy:
True
Has Adverse Events:
False
Brief Title:
Neural Development of Deductive Reasoning
Sponsor:
Organization:
Raw JSON
{'hasResults': False, 'derivedSection': {'miscInfoModule': {'versionHolder': '2025-12-24'}}, 'protocolSection': {'designModule': {'phases': ['NA'], 'studyType': 'INTERVENTIONAL', 'designInfo': {'allocation': 'NA', 'maskingInfo': {'masking': 'NONE'}, 'primaryPurpose': 'BASIC_SCIENCE', 'interventionModel': 'SINGLE_GROUP'}, 'enrollmentInfo': {'type': 'ESTIMATED', 'count': 60}}, 'statusModule': {'overallStatus': 'UNKNOWN', 'lastKnownStatus': 'RECRUITING', 'startDateStruct': {'date': '2013-10'}, 'expandedAccessInfo': {'hasExpandedAccess': False}, 'statusVerifiedDate': '2016-05', 'completionDateStruct': {'date': '2016-12', 'type': 'ESTIMATED'}, 'lastUpdateSubmitDate': '2016-05-03', 'studyFirstSubmitDate': '2016-05-03', 'studyFirstSubmitQcDate': '2016-05-03', 'lastUpdatePostDateStruct': {'date': '2016-05-05', 'type': 'ESTIMATED'}, 'studyFirstPostDateStruct': {'date': '2016-05-05', 'type': 'ESTIMATED'}, 'primaryCompletionDateStruct': {'date': '2016-12', 'type': 'ESTIMATED'}}, 'outcomesModule': {'primaryOutcomes': [{'measure': 'Identification of brain regions engaged in linear-order and set-inclusion reasoning', 'timeFrame': '30 days', 'description': 'Brain activity measured using fMRI'}], 'secondaryOutcomes': [{'measure': 'Degree of overlap between brain regions involved in linear-order and set-inclusion reasoning', 'timeFrame': '30 days', 'description': 'Degree of overlap in brain activity measured using fMRI'}]}, 'oversightModule': {'oversightHasDmc': False}, 'conditionsModule': {'keywords': ['fMRI', 'reasoning', 'development'], 'conditions': ['Healthy Volunteers']}, 'descriptionModule': {'briefSummary': "Children's understanding of linear-order (e.g., Dan is taller than Lisa, Lisa is taller than Jess) and set-inclusion (i.e., All tulips are flowers, All flowers are plants) relationships is critical for the acquisition of deductive reasoning, that is, the ability to reach logically valid conclusions from given premises. Behavioral and neuroimaging studies in adults suggest processing differences between these relations: While arguments that involve linear-orders may be preferentially associated with spatial processing, arguments that involve set-inclusions may be preferentially associated with verbal processing. In this study, we use functional magnetic resonance imaging to investigate how and when these processing differences appear in children from 8 to 14."}, 'eligibilityModule': {'sex': 'ALL', 'stdAges': ['CHILD'], 'maximumAge': '14 Years', 'minimumAge': '8 Years', 'healthyVolunteers': True, 'eligibilityCriteria': 'Inclusion Criteria:\n\n* Right-handed\n* Affiliated to the French social security\n* Whose parents gave informed consent\n\nExclusion Criteria:\n\n* Neurological disorders\n* Psychiatric disorders\n* Birth complications requiring admission into neonatal intensive care unit\n* Medication affecting central nervous system processing\n* Significant hearing impairment\n* Uncorrected visual impairment\n* Non-native English speaker\n* Contraindications for MRI'}, 'identificationModule': {'nctId': 'NCT02763657', 'acronym': 'NEUREAS', 'briefTitle': 'Neural Development of Deductive Reasoning', 'organization': {'class': 'OTHER', 'fullName': 'Hospices Civils de Lyon'}, 'officialTitle': 'Neural Development of Deductive Reasoning: an fMRI Study of Relational and Categorical Reasoning in Children', 'orgStudyIdInfo': {'id': '2012.767'}}, 'armsInterventionsModule': {'armGroups': [{'type': 'EXPERIMENTAL', 'label': 'Brain activity during reasoning', 'interventionNames': ['Other: fMRI scanning']}], 'interventions': [{'name': 'fMRI scanning', 'type': 'OTHER', 'description': 'All participants are scanned while evaluating linear-order and set-inclusion reasoning problems', 'armGroupLabels': ['Brain activity during reasoning']}]}, 'contactsLocationsModule': {'locations': [{'zip': '69500', 'city': 'Lyon/bron', 'status': 'RECRUITING', 'country': 'France', 'contacts': [{'name': 'Juistine EPINAT, CRA', 'role': 'CONTACT', 'email': 'jepinat@isc.cnrs.fr', 'phone': '4 37 91 12 64', 'phoneExt': '+33'}], 'facility': 'Hospices Civils de Lyon'}], 'centralContacts': [{'name': 'Christian SCHEIBER, Pr, MD', 'role': 'CONTACT', 'email': 'christian.scheiber@chu-lyon.fr', 'phone': '4 72 68 49 61', 'phoneExt': '+33'}, {'name': 'Justine EPINAT, CRA', 'role': 'CONTACT', 'email': 'jepinat@isc.cnrs.fr', 'phone': '4 37 91 12 64', 'phoneExt': '+ 33'}]}, 'ipdSharingStatementModule': {'ipdSharing': 'NO'}, 'sponsorCollaboratorsModule': {'leadSponsor': {'name': 'Hospices Civils de Lyon', 'class': 'OTHER'}, 'responsibleParty': {'type': 'SPONSOR'}}}}