Ignite Creation Date:
2025-12-24 @ 5:57 PM
Ignite Modification Date:
2025-12-29 @ 4:38 AM
Study NCT ID:
NCT07012668
Status:
RECRUITING
Last Update Posted:
2025-06-12
First Post:
2025-06-01
Is NOT Gene Therapy:
True
Has Adverse Events:
False
Brief Title:
Outcomes and Risk Factors of Different Treatment Strategies for Neuro-co-cardiological Diseases and Post-cardiac Surgery Cerebrovascular Diseases
Sponsor:
Organization:
Raw JSON
{'hasResults': False, 'derivedSection': {'miscInfoModule': {'versionHolder': '2025-12-24'}, 'interventionBrowseModule': {'meshes': [{'id': 'D008722', 'term': 'Methods'}, {'id': 'D013514', 'term': 'Surgical Procedures, Operative'}], 'ancestors': [{'id': 'D008919', 'term': 'Investigative Techniques'}]}}, 'protocolSection': {'designModule': {'studyType': 'OBSERVATIONAL', 'designInfo': {'timePerspective': 'OTHER', 'observationalModel': 'COHORT'}, 'enrollmentInfo': {'type': 'ESTIMATED', 'count': 2000}, 'targetDuration': '1 Year', 'patientRegistry': True}, 'statusModule': {'overallStatus': 'RECRUITING', 'startDateStruct': {'date': '2024-09-19', 'type': 'ACTUAL'}, 'expandedAccessInfo': {'hasExpandedAccess': False}, 'statusVerifiedDate': '2025-06', 'completionDateStruct': {'date': '2027-09-19', 'type': 'ESTIMATED'}, 'lastUpdateSubmitDate': '2025-06-09', 'studyFirstSubmitDate': '2025-06-01', 'studyFirstSubmitQcDate': '2025-06-01', 'lastUpdatePostDateStruct': {'date': '2025-06-12', 'type': 'ACTUAL'}, 'studyFirstPostDateStruct': {'date': '2025-06-10', 'type': 'ACTUAL'}, 'primaryCompletionDateStruct': {'date': '2027-09-19', 'type': 'ESTIMATED'}}, 'outcomesModule': {'primaryOutcomes': [{'measure': 'Modified Rankin Scale Score', 'timeFrame': '90±7 days', 'description': 'Modified Rankin Scale（0-6）, A lower MRS score indicates better functional status for the patient.'}], 'secondaryOutcomes': [{'measure': 'Modified Rankin Scale Score', 'timeFrame': '7±1 days or the day discharged', 'description': 'Modified Rankin Scale（0-6）, A lower MRS score indicates better functional status for the patient.'}, {'measure': 'Modified Rankin Scale Score', 'timeFrame': '365±30 days', 'description': 'Modified Rankin Scale（0-6）, A lower MRS score indicates better functional status for the patient.'}, {'measure': 'Perioperative complication rate', 'timeFrame': '30±7 days'}, {'measure': 'Rate of cardiovascular and cerebrovascular events', 'timeFrame': '90±7 days'}, {'measure': 'Rate of cardiovascular and cerebrovascular events', 'timeFrame': '365±30 days'}, {'measure': 'Short-term complications', 'timeFrame': '90±7 days'}, {'measure': 'Long-term complications', 'timeFrame': '365±30 days'}]}, 'oversightModule': {'isUsExport': False, 'oversightHasDmc': True, 'isFdaRegulatedDrug': False, 'isFdaRegulatedDevice': False}, 'conditionsModule': {'keywords': ['Neuro-co-cardiological diseases', 'Post-cardiac surgery Cerebrovascular diseases', 'Simultaneous treatment', 'Staged treatment', 'Conservative treatment'], 'conditions': ['Neuro-co-cardiological Diseases', 'Post-cardiac Surgery Cerebrovascular Diseases', 'Vascular Lesion']}, 'descriptionModule': {'briefSummary': 'The objective of this observational cohort study is to evaluate the clinical outcomes of various treatment strategies for cerebrovascular and cardiovascular diseases. Furthermore, it aims to investigate the factors that influence adverse outcomes from these treatments.'}, 'eligibilityModule': {'sex': 'ALL', 'stdAges': ['ADULT', 'OLDER_ADULT'], 'minimumAge': '18 Years', 'samplingMethod': 'PROBABILITY_SAMPLE', 'studyPopulation': 'Patients with neuro-co-cardiological diseases or post-cardiac surgery cerebrovascular diseases', 'healthyVolunteers': False, 'eligibilityCriteria': 'Inclusion Criteria:\n\n1. Age ≥18 years;\n2. Patients with neuro-co-cardiological diseases or post-cardiac surgery cerebrovascular diseases.\n\nExclusion Criteria:\n\n1. The expected survival is less than 1 years;\n2. Simultaneously merge other serious diseases;'}, 'identificationModule': {'nctId': 'NCT07012668', 'briefTitle': 'Outcomes and Risk Factors of Different Treatment Strategies for Neuro-co-cardiological Diseases and Post-cardiac Surgery Cerebrovascular Diseases', 'organization': {'class': 'OTHER', 'fullName': 'Beijing Anzhen Hospital'}, 'officialTitle': 'Outcomes and Risk Factors of Different Treatment Strategies for Neuro-co-cardiological Diseases and Post-cardiac Surgery Cerebrovascular Diseases', 'orgStudyIdInfo': {'id': 'ANGEL-NEUROCARD'}}, 'armsInterventionsModule': {'armGroups': [{'label': 'Neuro-co-cardiological diseases: Simultaneous treatment', 'description': 'Simultaneous interventional therapy/Simultaneous surgical treatment/ Simultaneous hybrid surgical treatment', 'interventionNames': ['Procedure: Interventional or surgical treatment']}, {'label': 'Neuro-co-cardiological diseases: Staged treatment', 'description': 'Staged interventional therapy/Staged surgical treatment/Staged hybrid surgical treatment', 'interventionNames': ['Procedure: Interventional or surgical treatment']}, {'label': 'Neuro-co-cardiological diseases: Conservative treatment', 'description': 'Surgery/intervention for one disease and conservative treatment for another disease or Simultaneously conservative treatment'}, {'label': 'Post-cardiac surgery Cerebrovascular disease: Surgery/Interventional Treatment', 'description': 'Post-cardiac surgery Cerebrovascular disease: Surgery/Interventional Treatment', 'interventionNames': ['Procedure: Interventional or surgical treatment']}, {'label': 'Post-cardiac surgery Cerebrovascular disease: Conservative treatment', 'description': 'Post-cardiac surgery Cerebrovascular disease: Conservative treatment'}], 'interventions': [{'name': 'Interventional or surgical treatment', 'type': 'PROCEDURE', 'description': 'Simultaneous interventional or surgical treatment/staged interventional or surgical treatment', 'armGroupLabels': ['Neuro-co-cardiological diseases: Simultaneous treatment', 'Neuro-co-cardiological diseases: Staged treatment']}, {'name': 'Interventional or surgical treatment', 'type': 'PROCEDURE', 'description': 'Interventional or surgical treatment', 'armGroupLabels': ['Post-cardiac surgery Cerebrovascular disease: Surgery/Interventional Treatment']}]}, 'contactsLocationsModule': {'locations': [{'city': 'Beijing', 'status': 'RECRUITING', 'country': 'China', 'contacts': [{'name': 'Xin Tong, M.D.', 'role': 'CONTACT', 'email': 'Tomice123@foxmail.com', 'phone': '17810651085', 'phoneExt': '86'}], 'facility': 'Beijing Anzhen Hospital', 'geoPoint': {'lat': 39.9075, 'lon': 116.39723}}], 'centralContacts': [{'name': 'Xiaochuan Huo, M.D.', 'role': 'CONTACT', 'email': 'huoxiaochuan@126.com', 'phone': '+86 13716292262'}, {'name': 'Xin Tong, M.D.', 'role': 'CONTACT', 'email': 'Tomice123@foxmail.com', 'phone': '+86 17810651085'}]}, 'ipdSharingStatementModule': {'ipdSharing': 'NO'}, 'sponsorCollaboratorsModule': {'leadSponsor': {'name': 'Beijing Anzhen Hospital', 'class': 'OTHER'}, 'responsibleParty': {'type': 'PRINCIPAL_INVESTIGATOR', 'investigatorTitle': 'Prof', 'investigatorFullName': 'Xiaochuan Huo', 'investigatorAffiliation': 'Beijing Anzhen Hospital'}}}}