Ignite Creation Date:
2025-12-24 @ 12:36 PM
Ignite Modification Date:
2025-12-27 @ 9:23 PM
Study NCT ID:
NCT03230461
Status:
COMPLETED
Last Update Posted:
2017-08-09
First Post:
2017-07-21
Is Gene Therapy:
True
Has Adverse Events:
False
Brief Title:
Estimation of CPR Chest Compression Depth
Sponsor:
Organization:
Raw JSON
{'hasResults': False, 'derivedSection': {'miscInfoModule': {'versionHolder': '2025-12-24'}, 'conditionBrowseModule': {'meshes': [{'id': 'D006323', 'term': 'Heart Arrest'}], 'ancestors': [{'id': 'D006331', 'term': 'Heart Diseases'}, {'id': 'D002318', 'term': 'Cardiovascular Diseases'}]}}, 'protocolSection': {'designModule': {'phases': ['NA'], 'studyType': 'INTERVENTIONAL', 'designInfo': {'allocation': 'RANDOMIZED', 'maskingInfo': {'masking': 'DOUBLE', 'whoMasked': ['PARTICIPANT', 'INVESTIGATOR'], 'maskingDescription': 'Participants and researchers are blinded to the actual depth achieved during each CPR run.'}, 'primaryPurpose': 'TREATMENT', 'interventionModel': 'SEQUENTIAL', 'interventionModelDescription': 'Prospective, randomised.'}, 'enrollmentInfo': {'type': 'ACTUAL', 'count': 100}}, 'statusModule': {'overallStatus': 'COMPLETED', 'startDateStruct': {'date': '2016-10', 'type': 'ACTUAL'}, 'expandedAccessInfo': {'hasExpandedAccess': False}, 'statusVerifiedDate': '2017-08', 'completionDateStruct': {'date': '2017-08-07', 'type': 'ACTUAL'}, 'lastUpdateSubmitDate': '2017-08-08', 'studyFirstSubmitDate': '2017-07-21', 'studyFirstSubmitQcDate': '2017-07-25', 'lastUpdatePostDateStruct': {'date': '2017-08-09', 'type': 'ACTUAL'}, 'studyFirstPostDateStruct': {'date': '2017-07-26', 'type': 'ACTUAL'}, 'primaryCompletionDateStruct': {'date': '2017-08-07', 'type': 'ACTUAL'}}, 'outcomesModule': {'primaryOutcomes': [{'measure': 'Compression to target window depth', 'timeFrame': 'Two minutes', 'description': 'Mean compression depth'}], 'secondaryOutcomes': [{'measure': 'Compression to target rate', 'timeFrame': 'Two minutes', 'description': 'Mean compression rate'}]}, 'oversightModule': {'oversightHasDmc': False, 'isFdaRegulatedDrug': False, 'isFdaRegulatedDevice': False}, 'conditionsModule': {'keywords': ['CPR', 'Basic life support'], 'conditions': ['Cardiac Arrest']}, 'descriptionModule': {'briefSummary': 'Optimal chest compression depth during CPR is 4.56cm which is at variance with the current guidelines of 5.0-6.0cm. A change in guidelines is only worthwhile if healthcare professionals can accurately judge a subtle reduction in chest compression depth during CPR by a relatively small amount.', 'detailedDescription': 'Chest compression depth and rate during cardiopulmonary resuscitation (CPR) are important predictors of return of spontaneous circulation and survival following cardiac arrest. Stiell et al (2014) found optimal survival at a compression depth of 4.56cm, which is at variance with the current guidelines of 5.0-6.0cm. A change in guidelines is only likely to improve survival rates if healthcare professionals can accurately implement these subtle depth modifications into the basic life support (BLS) algorithm. This study aims to determine if healthcare professionals can accurately judge compression depth without real-time feedback.'}, 'eligibilityModule': {'sex': 'ALL', 'stdAges': ['ADULT', 'OLDER_ADULT'], 'minimumAge': '18 Years', 'healthyVolunteers': True, 'eligibilityCriteria': 'Inclusion Criteria:\n\n* NHS professionals (staff or students), who have successfully completed a hospital-accredited basic life support (BLS) course, including a practical CPR component.\n\nExclusion Criteria:\n\n* Pregnancy, significant medical illness or injury that would impair delivery of chest compressions'}, 'identificationModule': {'nctId': 'NCT03230461', 'briefTitle': 'Estimation of CPR Chest Compression Depth', 'organization': {'class': 'OTHER', 'fullName': 'University Hospital Southampton NHS Foundation Trust'}, 'officialTitle': 'Can Rescuers Accurately Deliver Subtle Changes to Chest Compression Depth if Recommended by Future Guidelines?', 'orgStudyIdInfo': {'id': '19575'}}, 'armsInterventionsModule': {'armGroups': [{'type': 'EXPERIMENTAL', 'label': 'Target compression depth 4.0-5.0 cm', 'description': 'The rescuer is asked to perform two minutes of chest compressions on a manikin, aiming to compress to the target depth at a rate of 100-120/min', 'interventionNames': ['Behavioral: Compression depth']}, {'type': 'EXPERIMENTAL', 'label': 'Target compression depth 4.5-5.5 cm', 'description': 'The rescuer is asked to perform two minutes of chest compressions on a manikin, aiming to compress to the target depth at a rate of 100-120/min', 'interventionNames': ['Behavioral: Compression depth']}, {'type': 'EXPERIMENTAL', 'label': 'Target compression depth 5.0-6.0 cm', 'description': 'The rescuer is asked to perform two minutes of chest compressions on a manikin, aiming to compress to the target depth at a rate of 100-120/min', 'interventionNames': ['Behavioral: Compression depth']}], 'interventions': [{'name': 'Compression depth', 'type': 'BEHAVIORAL', 'armGroupLabels': ['Target compression depth 4.0-5.0 cm', 'Target compression depth 4.5-5.5 cm', 'Target compression depth 5.0-6.0 cm']}]}, 'contactsLocationsModule': {'locations': [{'zip': 'SO16 6YD', 'city': 'Southampton', 'state': 'Hampshire', 'country': 'United Kingdom', 'facility': 'University Hospital Southampton', 'geoPoint': {'lat': 50.90395, 'lon': -1.40428}}], 'overallOfficials': [{'name': 'Charles Deakin, MD', 'role': 'PRINCIPAL_INVESTIGATOR', 'affiliation': 'University Hospital Southampton NHS Foundation Trust'}]}, 'ipdSharingStatementModule': {'ipdSharing': 'UNDECIDED', 'description': 'Available on request'}, 'sponsorCollaboratorsModule': {'leadSponsor': {'name': 'University Hospital Southampton NHS Foundation Trust', 'class': 'OTHER'}, 'collaborators': [{'name': 'University of Southampton', 'class': 'OTHER'}], 'responsibleParty': {'type': 'SPONSOR'}}}}