Ignite Creation Date:
2025-12-24 @ 5:25 PM
Ignite Modification Date:
2026-02-23 @ 4:31 AM
Study NCT ID:
NCT00144950
Status:
COMPLETED
Last Update Posted:
2005-09-05
First Post:
2005-09-02
Is NOT Gene Therapy:
True
Has Adverse Events:
False
Brief Title:
Urokinase Versus Primary Video-Assisted Thorascopic Surgery for Empyema
Sponsor:
Organization:
Raw JSON
{'hasResults': False, 'derivedSection': {'miscInfoModule': {'versionHolder': '2025-12-24'}, 'conditionBrowseModule': {'meshes': [{'id': 'D004653', 'term': 'Empyema'}], 'ancestors': [{'id': 'D013492', 'term': 'Suppuration'}, {'id': 'D007239', 'term': 'Infections'}, {'id': 'D007249', 'term': 'Inflammation'}, {'id': 'D010335', 'term': 'Pathologic Processes'}, {'id': 'D013568', 'term': 'Pathological Conditions, Signs and Symptoms'}]}}, 'protocolSection': {'designModule': {'phases': ['PHASE1'], 'studyType': 'INTERVENTIONAL', 'designInfo': {'allocation': 'RANDOMIZED', 'maskingInfo': {'masking': 'NONE'}, 'primaryPurpose': 'TREATMENT', 'interventionModel': 'PARALLEL'}, 'enrollmentInfo': {'count': 60}}, 'statusModule': {'overallStatus': 'COMPLETED', 'expandedAccessInfo': {'hasExpandedAccess': False}, 'statusVerifiedDate': '2005-09', 'lastUpdateSubmitDate': '2005-09-02', 'studyFirstSubmitDate': '2005-09-02', 'studyFirstSubmitQcDate': '2005-09-02', 'lastUpdatePostDateStruct': {'date': '2005-09-05', 'type': 'ESTIMATED'}, 'studyFirstPostDateStruct': {'date': '2005-09-05', 'type': 'ESTIMATED'}}, 'outcomesModule': {'primaryOutcomes': [{'measure': 'length of hospital stay'}], 'secondaryOutcomes': [{'measure': 'radiological changes at follow up'}]}, 'conditionsModule': {'conditions': ['Empyema']}, 'referencesModule': {'references': [{'pmid': '18492739', 'type': 'DERIVED', 'citation': 'Jaffe A, Calder AD, Owens CM, Stanojevic S, Sonnappa S. Role of routine computed tomography in paediatric pleural empyema. Thorax. 2008 Oct;63(10):897-902. doi: 10.1136/thx.2007.094250. Epub 2008 May 20.'}]}, 'descriptionModule': {'briefSummary': 'This study will compare VATS versus chest drain insertion and urokinase in the treatment of childhood empema by a randomised prospective study.'}, 'eligibilityModule': {'sex': 'ALL', 'stdAges': ['CHILD'], 'maximumAge': '16 Years', 'minimumAge': '0 Years', 'healthyVolunteers': False, 'eligibilityCriteria': 'Inclusion Criteria:\n\n* patients under the age of 16 referred to GOSH for management of empyema\n\nExclusion Criteria:\n\n\\-'}, 'identificationModule': {'nctId': 'NCT00144950', 'briefTitle': 'Urokinase Versus Primary Video-Assisted Thorascopic Surgery for Empyema', 'organization': {'class': 'OTHER', 'fullName': 'Institute of Child Health'}, 'orgStudyIdInfo': {'id': '02AR04'}}, 'armsInterventionsModule': {'interventions': [{'name': 'insertion of a chest drain with urokinase instillation', 'type': 'DRUG'}, {'name': 'primary video-assisted thorascopic surgery', 'type': 'PROCEDURE'}]}, 'contactsLocationsModule': {'locations': [{'city': 'London', 'country': 'United Kingdom', 'facility': 'Great Ormond Street Hospital', 'geoPoint': {'lat': 51.50853, 'lon': -0.12574}}], 'overallOfficials': [{'name': 'Adam Jaffe, Dr', 'role': 'PRINCIPAL_INVESTIGATOR', 'affiliation': 'Great Ormond Street Hospital'}]}, 'sponsorCollaboratorsModule': {'leadSponsor': {'name': 'Institute of Child Health', 'class': 'OTHER'}}}}