Ignite Creation Date:
2025-12-24 @ 5:18 PM
Ignite Modification Date:
2026-01-02 @ 9:46 AM
Study NCT ID:
NCT00447850
Status:
COMPLETED
Last Update Posted:
2009-09-21
First Post:
2007-03-13
Is NOT Gene Therapy:
True
Has Adverse Events:
False
Brief Title:
Endometrial Gene Expression Profile in Controlled Ovarian Stimulation Cycles With Premature Luteinization
Sponsor:
Organization:
Raw JSON
{'hasResults': False, 'derivedSection': {'miscInfoModule': {'versionHolder': '2025-12-24'}}, 'protocolSection': {'designModule': {'phases': ['NA'], 'studyType': 'INTERVENTIONAL'}, 'statusModule': {'overallStatus': 'COMPLETED', 'startDateStruct': {'date': '2007-04'}, 'expandedAccessInfo': {'hasExpandedAccess': False}, 'statusVerifiedDate': '2009-09', 'completionDateStruct': {'date': '2009-07', 'type': 'ACTUAL'}, 'lastUpdateSubmitDate': '2009-09-18', 'studyFirstSubmitDate': '2007-03-13', 'studyFirstSubmitQcDate': '2007-03-13', 'lastUpdatePostDateStruct': {'date': '2009-09-21', 'type': 'ESTIMATED'}, 'studyFirstPostDateStruct': {'date': '2007-03-15', 'type': 'ESTIMATED'}, 'primaryCompletionDateStruct': {'date': '2009-07', 'type': 'ACTUAL'}}, 'conditionsModule': {'conditions': ['Premature Luteinization']}, 'descriptionModule': {'briefSummary': 'Previous studies have suggested that premature luteinization (PL)during controlled ovarian stimulation (COS) decreases the implantation rate due to a negative effect on the endometrium receptivity. This study aims to describe the impact on endometrial gene expression of PL in GnRH antagonist and GnRH agonist cycles.'}, 'eligibilityModule': {'sex': 'FEMALE', 'stdAges': ['ADULT'], 'maximumAge': '35 Years', 'minimumAge': '18 Years', 'healthyVolunteers': True, 'eligibilityCriteria': 'Inclusion Criteria:\n\n* Oocyte donors\n* Age between 18-35 years old\n* BMI 18-29\n* NORMOGONADOTROPHICS\n* PROGESTERONE ≥ 1.2 ng/ml on hCG day\n\nExclusion Criteria:\n\n* PolyCystic Ovarian Syndrome (PCOS)\n* Endometriosis'}, 'identificationModule': {'nctId': 'NCT00447850', 'briefTitle': 'Endometrial Gene Expression Profile in Controlled Ovarian Stimulation Cycles With Premature Luteinization', 'organization': {'class': 'OTHER', 'fullName': 'Instituto Valenciano de Infertilidad, IVI VALENCIA'}, 'officialTitle': 'Endometrial Gene Expression Profile in Controlled Ovarian Stimulation Cycles With Premature Luteinization', 'orgStudyIdInfo': {'id': 'VLC-EL-1006- 307-2'}}, 'armsInterventionsModule': {'interventions': [{'name': 'endometrial biopsy', 'type': 'PROCEDURE'}]}, 'contactsLocationsModule': {'locations': [{'zip': '46015', 'city': 'Valencia', 'country': 'Spain', 'facility': 'Ivi Valencia', 'geoPoint': {'lat': 39.47391, 'lon': -0.37966}}], 'overallOfficials': [{'name': 'Elena Labarta, MD', 'role': 'PRINCIPAL_INVESTIGATOR', 'affiliation': 'Instituto Valenciano de la Infertilidad'}]}, 'sponsorCollaboratorsModule': {'leadSponsor': {'name': 'Instituto Valenciano de Infertilidad, IVI VALENCIA', 'class': 'OTHER'}, 'responsibleParty': {'oldNameTitle': 'Dr. Elena Labarta', 'oldOrganization': 'Instituto Valenciano de Infertilidad'}}}}