Ignite Creation Date:
2025-12-24 @ 5:07 PM
Ignite Modification Date:
2026-02-21 @ 4:42 PM
Study NCT ID:
NCT00417950
Status:
UNKNOWN
Last Update Posted:
2007-01-04
First Post:
2007-01-01
Is NOT Gene Therapy:
True
Has Adverse Events:
False
Brief Title:
Additional Glucose Lowering and Anti-Inflammatory Effects by Acarbose and Alcohol in Subjects With Impaired Glucose Tolerance or Mild Type 2 Diabetes
Sponsor:
Organization:
Raw JSON
{'hasResults': False, 'derivedSection': {'miscInfoModule': {'versionHolder': '2025-12-24'}, 'conditionBrowseModule': {'meshes': [{'id': 'D003920', 'term': 'Diabetes Mellitus'}, {'id': 'D018149', 'term': 'Glucose Intolerance'}, {'id': 'D007249', 'term': 'Inflammation'}], 'ancestors': [{'id': 'D044882', 'term': 'Glucose Metabolism Disorders'}, {'id': 'D008659', 'term': 'Metabolic Diseases'}, {'id': 'D009750', 'term': 'Nutritional and Metabolic Diseases'}, {'id': 'D004700', 'term': 'Endocrine System Diseases'}, {'id': 'D006943', 'term': 'Hyperglycemia'}, {'id': 'D010335', 'term': 'Pathologic Processes'}, {'id': 'D013568', 'term': 'Pathological Conditions, Signs and Symptoms'}]}, 'interventionBrowseModule': {'meshes': [{'id': 'D020909', 'term': 'Acarbose'}], 'ancestors': [{'id': 'D014312', 'term': 'Trisaccharides'}, {'id': 'D009844', 'term': 'Oligosaccharides'}, {'id': 'D011134', 'term': 'Polysaccharides'}, {'id': 'D002241', 'term': 'Carbohydrates'}]}}, 'protocolSection': {'designModule': {'phases': ['NA'], 'studyType': 'INTERVENTIONAL', 'designInfo': {'allocation': 'RANDOMIZED', 'maskingInfo': {'masking': 'NONE'}, 'primaryPurpose': 'TREATMENT', 'interventionModel': 'SINGLE_GROUP'}, 'enrollmentInfo': {'count': 30}}, 'statusModule': {'overallStatus': 'UNKNOWN', 'lastKnownStatus': 'RECRUITING', 'startDateStruct': {'date': '2007-01'}, 'expandedAccessInfo': {'hasExpandedAccess': False}, 'statusVerifiedDate': '2007-01', 'lastUpdateSubmitDate': '2007-01-03', 'studyFirstSubmitDate': '2007-01-01', 'studyFirstSubmitQcDate': '2007-01-03', 'lastUpdatePostDateStruct': {'date': '2007-01-04', 'type': 'ESTIMATED'}, 'studyFirstPostDateStruct': {'date': '2007-01-04', 'type': 'ESTIMATED'}}, 'outcomesModule': {'primaryOutcomes': [{'measure': 'Postprandial hyperglycemia'}], 'secondaryOutcomes': [{'measure': 'Postprandial inflammatory responses'}, {'measure': 'Postprandial oxidative stress'}]}, 'conditionsModule': {'keywords': ['diabetes', 'acarbose', 'alcohol', 'inflammation', 'oxidative stress', 'Mild diabetes mellitus'], 'conditions': ['Diabetes Mellitus', 'Impaired Glucose Tolerance']}, 'descriptionModule': {'briefSummary': 'To understand if acarbose, an alpha-glucosidase inhibitor usually for treating diabetes, will further lower post meal glucose and inflammatory state when taking together with moderate amount of alcohol during meal tolerance test in subjects with impaired glucose tolerance or mild diabetes.'}, 'eligibilityModule': {'sex': 'ALL', 'stdAges': ['ADULT', 'OLDER_ADULT'], 'maximumAge': '75 Years', 'minimumAge': '25 Years', 'healthyVolunteers': False, 'eligibilityCriteria': 'Inclusion Criteria:\n\n* Subjects with mild diabetes without prior medications or impaired glucose tolerance\n\nExclusion Criteria:\n\n* Pregnancy\n* Recent major cardiac, renal and hepatic disease\n* Intolerance to alcohol\n* Allergy to acarbose treatment'}, 'identificationModule': {'nctId': 'NCT00417950', 'briefTitle': 'Additional Glucose Lowering and Anti-Inflammatory Effects by Acarbose and Alcohol in Subjects With Impaired Glucose Tolerance or Mild Type 2 Diabetes', 'organization': {'class': 'OTHER', 'fullName': 'Taichung Veterans General Hospital'}, 'orgStudyIdInfo': {'id': '950801/C06138'}}, 'armsInterventionsModule': {'interventions': [{'name': 'Acarbose', 'type': 'DRUG'}]}, 'contactsLocationsModule': {'locations': [{'city': 'Taichung', 'status': 'RECRUITING', 'country': 'Taiwan', 'contacts': [{'name': 'Wayne H Sheu, MD, PhD', 'role': 'CONTACT', 'email': 'whhsheu@vghtc.gov.tw', 'phone': '886-4-23592525', 'phoneExt': '3068'}, {'name': 'Wayne H Sheu, MD, PhD', 'role': 'PRINCIPAL_INVESTIGATOR'}, {'name': 'I Te Lee, MD, MS', 'role': 'SUB_INVESTIGATOR'}], 'facility': 'Taichung Veterans General Hospital', 'geoPoint': {'lat': 24.1469, 'lon': 120.6839}}], 'centralContacts': [{'name': 'I Te Lee, MD, MS', 'role': 'CONTACT', 'email': 'itlee@vghtc.gov.tw', 'phone': '886-4-23592525', 'phoneExt': '3065'}], 'overallOfficials': [{'name': 'Wayne H Sheu, MD, PhD', 'role': 'PRINCIPAL_INVESTIGATOR', 'affiliation': 'Taichung Veterans General Hospital'}]}, 'sponsorCollaboratorsModule': {'leadSponsor': {'name': 'Taichung Veterans General Hospital', 'class': 'OTHER'}, 'collaborators': [{'name': 'Tri-Service General Hospital', 'class': 'OTHER'}]}}}