Ignite Creation Date:
2025-12-24 @ 4:52 PM
Ignite Modification Date:
2026-01-01 @ 6:10 AM
Study NCT ID:
NCT00919750
Status:
COMPLETED
Last Update Posted:
2018-07-16
First Post:
2009-06-11
Is Gene Therapy:
True
Has Adverse Events:
False
Brief Title:
Collecting and Storing Blood and Brain Tumor Tissue Samples From Children With Brain Tumors
Sponsor:
Organization:
Raw JSON
{'hasResults': False, 'derivedSection': {'miscInfoModule': {'versionHolder': '2025-12-24'}, 'conditionBrowseModule': {'meshes': [{'id': 'D018335', 'term': 'Rhabdoid Tumor'}, {'id': 'D001254', 'term': 'Astrocytoma'}, {'id': 'D016545', 'term': 'Choroid Plexus Neoplasms'}, {'id': 'D009837', 'term': 'Oligodendroglioma'}, {'id': 'D004806', 'term': 'Ependymoma'}, {'id': 'C531673', 'term': 'Familial ependymoma'}, {'id': 'D008527', 'term': 'Medulloblastoma'}, {'id': 'D020339', 'term': 'Optic Nerve Glioma'}], 'ancestors': [{'id': 'D018193', 'term': 'Neoplasms, Complex and Mixed'}, {'id': 'D009370', 'term': 'Neoplasms by Histologic Type'}, {'id': 'D009369', 'term': 'Neoplasms'}, {'id': 'D005910', 'term': 'Glioma'}, {'id': 'D018302', 'term': 'Neoplasms, Neuroepithelial'}, {'id': 'D017599', 'term': 'Neuroectodermal Tumors'}, {'id': 'D009373', 'term': 'Neoplasms, Germ Cell and Embryonal'}, {'id': 'D009375', 'term': 'Neoplasms, Glandular and Epithelial'}, {'id': 'D009380', 'term': 'Neoplasms, Nerve Tissue'}, {'id': 'D002551', 'term': 'Cerebral Ventricle Neoplasms'}, {'id': 'D001932', 'term': 'Brain Neoplasms'}, {'id': 'D016543', 'term': 'Central Nervous System Neoplasms'}, {'id': 'D009423', 'term': 'Nervous System Neoplasms'}, {'id': 'D009371', 'term': 'Neoplasms by Site'}, {'id': 'D001927', 'term': 'Brain Diseases'}, {'id': 'D002493', 'term': 'Central Nervous System Diseases'}, {'id': 'D009422', 'term': 'Nervous System Diseases'}, {'id': 'D018242', 'term': 'Neuroectodermal Tumors, Primitive'}, {'id': 'D019574', 'term': 'Optic Nerve Neoplasms'}, {'id': 'D003390', 'term': 'Cranial Nerve Neoplasms'}, {'id': 'D010524', 'term': 'Peripheral Nervous System Neoplasms'}, {'id': 'D003389', 'term': 'Cranial Nerve Diseases'}, {'id': 'D009901', 'term': 'Optic Nerve Diseases'}, {'id': 'D005128', 'term': 'Eye Diseases'}]}}, 'protocolSection': {'designModule': {'studyType': 'OBSERVATIONAL', 'enrollmentInfo': {'type': 'ACTUAL', 'count': 1258}}, 'statusModule': {'overallStatus': 'COMPLETED', 'startDateStruct': {'date': '2004-02-16', 'type': 'ACTUAL'}, 'expandedAccessInfo': {'hasExpandedAccess': False}, 'statusVerifiedDate': '2018-07', 'completionDateStruct': {'date': '2018-06-30', 'type': 'ACTUAL'}, 'lastUpdateSubmitDate': '2018-07-12', 'studyFirstSubmitDate': '2009-06-11', 'studyFirstSubmitQcDate': '2009-06-11', 'lastUpdatePostDateStruct': {'date': '2018-07-16', 'type': 'ACTUAL'}, 'studyFirstPostDateStruct': {'date': '2009-06-12', 'type': 'ESTIMATED'}, 'primaryCompletionDateStruct': {'date': '2018-06-30', 'type': 'ACTUAL'}}, 'outcomesModule': {'primaryOutcomes': [{'measure': 'Collection of brain tumor tissue and an accompanying blood sample from pediatric patients with brain tumors treated at Children?s Oncology Group institutions', 'timeFrame': 'Up to 16 years'}, {'measure': 'Creation of a repository for long-term storage of these specimens', 'timeFrame': 'Up to 16 years'}, {'measure': 'Making these specimens available to qualified researchers to understand the biology of pediatric brain tumors', 'timeFrame': 'Up to 16 years'}]}, 'conditionsModule': {'conditions': ['Childhood Atypical Teratoid/Rhabdoid Tumor', 'Childhood Central Nervous System Germ Cell Tumor', 'Childhood Cerebral Anaplastic Astrocytoma', 'Childhood Cerebral Astrocytoma', 'Childhood Choroid Plexus Neoplasm', 'Childhood Craniopharyngioma', 'Childhood Grade I Meningioma', 'Childhood Grade II Meningioma', 'Childhood Grade III Meningioma', 'Childhood Infratentorial Ependymoma', 'Childhood Oligodendroglioma', 'Childhood Supratentorial Ependymoma', 'Ependymoma', 'Newly Diagnosed Childhood Ependymoma', 'Recurrent Childhood Cerebellar Astrocytoma', 'Recurrent Childhood Cerebral Astrocytoma', 'Recurrent Childhood Ependymoma', 'Recurrent Childhood Medulloblastoma', 'Recurrent Childhood Supratentorial Embryonal Tumor, Not Otherwise Specified', 'Recurrent Childhood Visual Pathway Glioma']}, 'descriptionModule': {'briefSummary': 'The purpose of this study is to collect and store brain tissue samples and blood from children with brain cancer that will be tested in the laboratory. Collecting and storing samples of tumor tissue and blood from patients to test in the laboratory may help the study of cancer in the future.', 'detailedDescription': 'OBJECTIVES:\n\nI. Collect brain tumor tissue and an accompanying blood sample from pediatric patients with brain tumors treated at Children?s Oncology Group institutions.\n\nII. Provide a repository for long-term storage of specimens from these patients.\n\nIII. Make these specimens available to qualified researchers to understand the biology of pediatric brain tumors.\n\nOUTLINE: This is a multicenter study.\n\nBrain tumor tissue and blood specimens are collected from patients and banked for future study.'}, 'eligibilityModule': {'sex': 'ALL', 'stdAges': ['CHILD', 'ADULT'], 'maximumAge': '18 Years', 'samplingMethod': 'NON_PROBABILITY_SAMPLE', 'healthyVolunteers': False, 'eligibilityCriteria': 'Inclusion Criteria:\n\n* Diagnosis of brain tumor\n* Previously treated at a Children?s Oncology Group (COG) institution\n\n * Patients are eligible at time of diagnosis, second-look surgery, recurrence, or development of a second malignant neoplasm\n* Must have brain tumor biological specimens derived from primary tumors of the CNS available for submission'}, 'identificationModule': {'nctId': 'NCT00919750', 'briefTitle': 'Collecting and Storing Blood and Brain Tumor Tissue Samples From Children With Brain Tumors', 'nctIdAliases': ['NCT00228748'], 'organization': {'class': 'NETWORK', 'fullName': "Children's Oncology Group"}, 'officialTitle': "A Children's Oncology Group Protocol for Collecting and Banking Pediatric Brain Tumor Research Specimens", 'orgStudyIdInfo': {'id': 'ACNS02B3'}, 'secondaryIdInfos': [{'id': 'NCI-2009-00334', 'type': 'REGISTRY', 'domain': 'CTRP (Clinical Trial Reporting Program)'}, {'id': 'COG-ACNS02B3'}, {'id': 'CDR0000352347'}, {'id': 'ACNS02B3', 'type': 'OTHER', 'domain': 'Childrens Oncology Group'}, {'id': 'ACNS02B3', 'type': 'OTHER', 'domain': 'CTEP'}, {'id': 'U10CA098543', 'link': 'https://reporter.nih.gov/quickSearch/U10CA098543', 'type': 'NIH'}, {'id': 'UG1CA189958', 'link': 'https://reporter.nih.gov/quickSearch/UG1CA189958', 'type': 'NIH'}]}, 'armsInterventionsModule': {'armGroups': [{'label': 'Ancillary-Correlative (tissue and blood sample collection)', 'description': 'Brain tumor tissue and blood specimens are collected from patients and banked for future study.', 'interventionNames': ['Other: Cytology Specimen Collection Procedure']}], 'interventions': [{'name': 'Cytology Specimen Collection Procedure', 'type': 'OTHER', 'otherNames': ['Cytologic Sampling'], 'description': 'Correlative studies', 'armGroupLabels': ['Ancillary-Correlative (tissue and blood sample collection)']}]}, 'contactsLocationsModule': {'locations': [{'zip': '35233', 'city': 'Birmingham', 'state': 'Alabama', 'country': 'United States', 'facility': "Children's Hospital of Alabama", 'geoPoint': {'lat': 33.52066, 'lon': -86.80249}}, {'zip': '35233', 'city': 'Birmingham', 'state': 'Alabama', 'country': 'United States', 'facility': 'University of Alabama at Birmingham Cancer Center', 'geoPoint': {'lat': 33.52066, 'lon': -86.80249}}, {'zip': '85016', 'city': 'Phoenix', 'state': 'Arizona', 'country': 'United States', 'facility': 'Phoenix Childrens Hospital', 'geoPoint': {'lat': 33.44838, 'lon': -112.07404}}, {'zip': '72202-3591', 'city': 'Little Rock', 'state': 'Arkansas', 'country': 'United States', 'facility': "Arkansas Children's Hospital", 'geoPoint': {'lat': 34.74648, 'lon': -92.28959}}, {'zip': '72205', 'city': 'Little Rock', 'state': 'Arkansas', 'country': 'United States', 'facility': 'University of Arkansas for Medical Sciences', 'geoPoint': {'lat': 34.74648, 'lon': -92.28959}}, {'zip': '90242', 'city': 'Downey', 'state': 'California', 'country': 'United States', 'facility': 'Kaiser Permanente Downey Medical Center', 'geoPoint': {'lat': 33.94001, 'lon': -118.13257}}, {'zip': '91010', 'city': 'Duarte', 'state': 'California', 'country': 'United States', 'facility': 'City of Hope Comprehensive Cancer Center', 'geoPoint': {'lat': 34.13945, 'lon': -117.97729}}, {'zip': '92354', 'city': 'Loma Linda', 'state': 'California', 'country': 'United States', 'facility': 'Loma Linda University Medical Center', 'geoPoint': {'lat': 34.04835, 'lon': -117.26115}}, {'zip': '90806', 'city': 'Long Beach', 'state': 'California', 'country': 'United States', 'facility': "Miller Children's and Women's Hospital 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