Ignite Creation Date:
2025-12-24 @ 4:32 PM
Ignite Modification Date:
2026-01-06 @ 10:55 PM
Study NCT ID:
NCT01249066
Status:
UNKNOWN
Last Update Posted:
2010-11-29
First Post:
2010-11-24
Is Gene Therapy:
True
Has Adverse Events:
False
Brief Title:
Expression of AMP-activated Protein Kinase (AMPK) Protein in Lung Adenocarcinoma
Sponsor:
Organization:
Raw JSON
{'hasResults': False, 'derivedSection': {'miscInfoModule': {'versionHolder': '2025-12-24'}, 'conditionBrowseModule': {'meshes': [{'id': 'D000077192', 'term': 'Adenocarcinoma of Lung'}], 'ancestors': [{'id': 'D000230', 'term': 'Adenocarcinoma'}, {'id': 'D002277', 'term': 'Carcinoma'}, {'id': 'D009375', 'term': 'Neoplasms, Glandular and Epithelial'}, {'id': 'D009370', 'term': 'Neoplasms by Histologic Type'}, {'id': 'D009369', 'term': 'Neoplasms'}, {'id': 'D008175', 'term': 'Lung Neoplasms'}, {'id': 'D012142', 'term': 'Respiratory Tract Neoplasms'}, {'id': 'D013899', 'term': 'Thoracic Neoplasms'}, {'id': 'D009371', 'term': 'Neoplasms by Site'}]}}, 'protocolSection': {'designModule': {'studyType': 'OBSERVATIONAL', 'designInfo': {'timePerspective': 'RETROSPECTIVE'}, 'enrollmentInfo': {'type': 'ESTIMATED', 'count': 100}}, 'statusModule': {'overallStatus': 'UNKNOWN', 'lastKnownStatus': 'RECRUITING', 'startDateStruct': {'date': '2010-09'}, 'expandedAccessInfo': {'hasExpandedAccess': False}, 'statusVerifiedDate': '2010-09', 'lastUpdateSubmitDate': '2010-11-26', 'studyFirstSubmitDate': '2010-11-24', 'studyFirstSubmitQcDate': '2010-11-26', 'lastUpdatePostDateStruct': {'date': '2010-11-29', 'type': 'ESTIMATED'}, 'studyFirstPostDateStruct': {'date': '2010-11-29', 'type': 'ESTIMATED'}}, 'oversightModule': {'oversightHasDmc': False}, 'conditionsModule': {'keywords': ['AMP-activated protein kinase', 'lung adenocarcinomas', 'Prognosis', 'Observation study'], 'conditions': ['Lung Adenocarcinoma']}, 'descriptionModule': {'briefSummary': 'AMP-activated protein kinase (AMPK) is an evolutionally conserved protein kinase that serves as an energy guardian to help cells adapt to various metabolic stress including hypoxia. Because the role of AMPK in cancers has not been fully elucidated, in this study we investigated the expression and activation of AMPK in lung adenocarcinoma (LADC) cells and tissue.'}, 'eligibilityModule': {'sex': 'ALL', 'stdAges': ['ADULT', 'OLDER_ADULT'], 'maximumAge': '85 Years', 'minimumAge': '25 Years', 'samplingMethod': 'NON_PROBABILITY_SAMPLE', 'studyPopulation': 'Lung cancer received lobectomy in CMUH', 'healthyVolunteers': False, 'eligibilityCriteria': 'Inclusion Criteria:\n\n* Lung cancer received operation lobectomy in CMUH\n\nExclusion Criteria:\n\n* History of uremia, other malignant disease, and liver cirrhosis\n* History of pneumonia and pulmonary tuberculosis\n* History of long period of medications.'}, 'identificationModule': {'nctId': 'NCT01249066', 'briefTitle': 'Expression of AMP-activated Protein Kinase (AMPK) Protein in Lung Adenocarcinoma', 'organization': {'class': 'OTHER', 'fullName': 'China Medical University Hospital'}, 'officialTitle': 'Expression of AMP-activated Protein Kinase (AMPK) Protein in Lung Adenocarcinoma', 'orgStudyIdInfo': {'id': 'DMR99-IRB-096'}}, 'contactsLocationsModule': {'locations': [{'zip': '404', 'city': 'Taichung', 'status': 'RECRUITING', 'country': 'Taiwan', 'contacts': [{'name': 'Hsin-Yuan Fang, MD', 'role': 'CONTACT', 'email': 'd93421104@ntu.edu.tw', 'phone': '+886422052121', 'phoneExt': '1638'}], 'facility': 'Fang Hsin Yuan', 'geoPoint': {'lat': 24.1469, 'lon': 120.6839}}]}, 'sponsorCollaboratorsModule': {'leadSponsor': {'name': 'China Medical University Hospital', 'class': 'OTHER'}, 'responsibleParty': {'oldNameTitle': 'Fang Hsin-Yuan/Director', 'oldOrganization': 'China Medical University Hospital'}}}}