Ignite Creation Date:
2025-12-24 @ 4:20 PM
Ignite Modification Date:
2026-01-04 @ 5:11 PM
Study NCT ID:
NCT06033066
Status:
COMPLETED
Last Update Posted:
2025-06-25
First Post:
2023-08-09
Is Gene Therapy:
True
Has Adverse Events:
False
Brief Title:
Financial Incentives and Recruitment to the APT Webstudy
Sponsor:
Organization:
Raw JSON
{'hasResults': False, 'derivedSection': {'miscInfoModule': {'versionHolder': '2025-12-24'}, 'conditionBrowseModule': {'meshes': [{'id': 'D000544', 'term': 'Alzheimer Disease'}, {'id': 'D003704', 'term': 'Dementia'}], 'ancestors': [{'id': 'D001927', 'term': 'Brain Diseases'}, {'id': 'D002493', 'term': 'Central Nervous System Diseases'}, {'id': 'D009422', 'term': 'Nervous System Diseases'}, {'id': 'D024801', 'term': 'Tauopathies'}, {'id': 'D019636', 'term': 'Neurodegenerative Diseases'}, {'id': 'D019965', 'term': 'Neurocognitive Disorders'}, {'id': 'D001523', 'term': 'Mental Disorders'}]}}, 'documentSection': {'largeDocumentModule': {'largeDocs': [{'date': '2023-09-06', 'size': 262869, 'label': 'Study Protocol', 'hasIcf': False, 'hasSap': False, 'filename': 'Prot_000.pdf', 'typeAbbrev': 'Prot', 'uploadDate': '2023-09-07T12:23', 'hasProtocol': True}]}}, 'protocolSection': {'designModule': {'phases': ['NA'], 'studyType': 'INTERVENTIONAL', 'designInfo': {'allocation': 'RANDOMIZED', 'maskingInfo': {'masking': 'NONE'}, 'primaryPurpose': 'HEALTH_SERVICES_RESEARCH', 'interventionModel': 'PARALLEL'}, 'enrollmentInfo': {'type': 'ACTUAL', 'count': 44844}}, 'statusModule': {'overallStatus': 'COMPLETED', 'startDateStruct': {'date': '2024-03-01', 'type': 'ACTUAL'}, 'expandedAccessInfo': {'hasExpandedAccess': False}, 'statusVerifiedDate': '2023-12', 'completionDateStruct': {'date': '2024-04-30', 'type': 'ACTUAL'}, 'lastUpdateSubmitDate': '2025-06-23', 'studyFirstSubmitDate': '2023-08-09', 'studyFirstSubmitQcDate': '2023-09-07', 'lastUpdatePostDateStruct': {'date': '2025-06-25', 'type': 'ACTUAL'}, 'studyFirstPostDateStruct': {'date': '2023-09-13', 'type': 'ACTUAL'}, 'primaryCompletionDateStruct': {'date': '2024-04-30', 'type': 'ACTUAL'}}, 'outcomesModule': {'primaryOutcomes': [{'measure': 'Enrollment status into the APT Webstudy', 'timeFrame': '2-weeks', 'description': 'APT Webstudy enrollment rate based on completion of at least one of the two APT Webstudy cognitive assessments (Cognitive Function Instrument \\[CFI\\] and/or Cogstate Brief Battery).'}], 'secondaryOutcomes': [{'measure': 'Cost per enrollee', 'timeFrame': 'annual', 'description': 'Cost to acquire an enrollment'}, {'measure': 'Completion of cognitive assessments within the APT Webstudy', 'timeFrame': '2-weeks', 'description': 'Completion of both APT Webstudy cognitive assessments (Cognitive Function Instrument \\[CFI\\] and/or Cogstate Brief Battery).'}]}, 'oversightModule': {'oversightHasDmc': False, 'isFdaRegulatedDrug': False, 'isFdaRegulatedDevice': False}, 'conditionsModule': {'keywords': ["Alzheimer's", 'Prevention', 'Observational', 'Trial-Ready Cohort'], 'conditions': ['Alzheimer Disease', 'Dementia', "Preclinical Alzheimer's Disease", "Prodromal Alzheimer's Disease"]}, 'referencesModule': {'references': [{'pmid': '40844772', 'type': 'DERIVED', 'citation': 'Jacobson M, Molina-Henry D, Chang TY, Jimenez-Maggiora GA, Pramanik R, Shah SB, Aisen PS. Financial Incentives to Increase Diversity of Older Participants in a Memory Concerns Registry: A Randomized Clinical Trial. JAMA Health Forum. 2025 Aug 1;6(8):e252273. doi: 10.1001/jamahealthforum.2025.2273.'}], 'seeAlsoLinks': [{'url': 'https://www.aptwebstudy.org/', 'label': 'APT Webstudy'}]}, 'descriptionModule': {'briefSummary': "This single-blind, three-arm, randomized, controlled trial will assess the impact of messages and financial incentives on the enrollment of demographically diverse individuals to the Alzheimer Prevention Trials (APT) Webstudy. The APT Webstudy is a novel, online registry that employs quarterly cognitive testing using validated platforms. The APT Webstudy implements fully remote assessments, coordinated by the Alzheimer's Therapeutic Research Institute (ATRI) under USC IRB #HS-17-00746. The purpose of the current study is to test whether we can increase enrollment of diverse individuals into the registry. To do this, we will work with Contra Costa Regional Medical Center (CCRMC), the county public hospital and its affiliated health centers in Contra Costa County, California, to test whether sending messages with and without financial incentives to patients who receive primary care with the health system can increase enrollment to the APT Webstudy. The investigators hypothesize that 1) a certain small financial incentive and an award opportunity based incentive (or a drawing with a prize) will increase enrollment rates of CCHS members into the APT Webstudy relative to the control group. The investigators further hypothesize that the award opportunity incentive will increase the enrollment rate of CCRMC patients into the APT Webstudy more than a certain financial incentive with the same expected value."}, 'eligibilityModule': {'sex': 'ALL', 'stdAges': ['ADULT', 'OLDER_ADULT'], 'minimumAge': '50 Years', 'healthyVolunteers': True, 'eligibilityCriteria': 'Inclusion Criteria:\n\nTo be eligible to participate in this study, an individual must meet all of the following criteria:\n\n* Patients empaneled at Contra Costa Regional Medical Center (CCRMC), the county public hospital and its affiliated health centers.\n* Age 50 or older\n* Literate in either English or Spanish\n\nExclusion Criteria:\n\n* Below age 50\n* Documentation of prior dementia diagnosis'}, 'identificationModule': {'nctId': 'NCT06033066', 'acronym': 'FIND-AD', 'briefTitle': 'Financial Incentives and Recruitment to the APT Webstudy', 'organization': {'class': 'OTHER', 'fullName': 'University of Southern California'}, 'officialTitle': 'A Randomized Trial of Financial Incentives for the Recruitment of County Health System Patients to the Alzheimer Prevention Trials (APT) Webstudy', 'orgStudyIdInfo': {'id': 'UP-22-01037'}}, 'armsInterventionsModule': {'armGroups': [{'type': 'ACTIVE_COMPARATOR', 'label': 'Messaging Only', 'description': '16,000 participants will be randomized to Arm 1 where no monetary incentive is offered.', 'interventionNames': ['Behavioral: Message']}, {'type': 'EXPERIMENTAL', 'label': 'Small Incentive', 'description': '16,000 participants will be randomized to Arm 2 where a small one-time monetary incentive is offered.', 'interventionNames': ['Behavioral: Financial Incentives']}, {'type': 'EXPERIMENTAL', 'label': 'Prize Incentive', 'description': '16,000 participants will be randomized to Arm 3 where an opportunity based incentive (or a drawing with a prize) with a single winner will be offered.', 'interventionNames': ['Behavioral: Financial Incentives']}], 'interventions': [{'name': 'Financial Incentives', 'type': 'BEHAVIORAL', 'description': 'Small financial incentive or prize incentive', 'armGroupLabels': ['Prize Incentive', 'Small Incentive']}, {'name': 'Message', 'type': 'BEHAVIORAL', 'description': 'Message inviting participant to enroll', 'armGroupLabels': ['Messaging Only']}]}, 'contactsLocationsModule': {'locations': [{'zip': '94553', 'city': 'Martinez', 'state': 'California', 'country': 'United States', 'facility': 'Contra Costa Health Plan', 'geoPoint': {'lat': 38.01937, 'lon': -122.13413}}]}, 'ipdSharingStatementModule': {'infoTypes': ['STUDY_PROTOCOL', 'SAP', 'ANALYTIC_CODE'], 'timeFrame': 'Data will be made available within 6 months of publication.', 'ipdSharing': 'YES', 'description': 'The health system will not allow sharing of individual data on a public site. However, we will share data on request from investigators.', 'accessCriteria': 'Individual data shared upon request.'}, 'sponsorCollaboratorsModule': {'leadSponsor': {'name': 'University of Southern California', 'class': 'OTHER'}, 'collaborators': [{'name': 'American Heart Association', 'class': 'OTHER'}, {'name': 'Schaeffer Center for Health Policy & Economics', 'class': 'UNKNOWN'}, {'name': "Alzheimer's Therapeutic Research Institute", 'class': 'OTHER'}], 'responsibleParty': {'type': 'PRINCIPAL_INVESTIGATOR', 'investigatorTitle': 'Associate Professor of Gerontology', 'investigatorFullName': 'Mireille Jacobson', 'investigatorAffiliation': 'University of Southern California'}}}}