Ignite Creation Date:
2025-12-24 @ 12:20 PM
Ignite Modification Date:
2025-12-27 @ 9:52 PM
Study NCT ID:
NCT04631861
Status:
COMPLETED
Last Update Posted:
2023-08-01
First Post:
2020-11-14
Is Gene Therapy:
True
Has Adverse Events:
False
Brief Title:
Physical Activity and the Risk of COVID-19 Infection and Mortality
Sponsor:
Organization:
Raw JSON
{'hasResults': False, 'derivedSection': {'miscInfoModule': {'versionHolder': '2025-12-24'}, 'conditionBrowseModule': {'meshes': [{'id': 'D000086382', 'term': 'COVID-19'}, {'id': 'D009043', 'term': 'Motor Activity'}], 'ancestors': [{'id': 'D011024', 'term': 'Pneumonia, Viral'}, {'id': 'D011014', 'term': 'Pneumonia'}, {'id': 'D012141', 'term': 'Respiratory Tract Infections'}, {'id': 'D007239', 'term': 'Infections'}, {'id': 'D014777', 'term': 'Virus Diseases'}, {'id': 'D018352', 'term': 'Coronavirus Infections'}, {'id': 'D003333', 'term': 'Coronaviridae Infections'}, {'id': 'D030341', 'term': 'Nidovirales Infections'}, {'id': 'D012327', 'term': 'RNA Virus Infections'}, {'id': 'D008171', 'term': 'Lung Diseases'}, {'id': 'D012140', 'term': 'Respiratory Tract Diseases'}, {'id': 'D001519', 'term': 'Behavior'}]}}, 'protocolSection': {'designModule': {'studyType': 'OBSERVATIONAL', 'designInfo': {'timePerspective': 'RETROSPECTIVE', 'observationalModel': 'CASE_CONTROL'}, 'enrollmentInfo': {'type': 'ACTUAL', 'count': 132069}, 'patientRegistry': False}, 'statusModule': {'overallStatus': 'COMPLETED', 'startDateStruct': {'date': '2014-01-01', 'type': 'ACTUAL'}, 'expandedAccessInfo': {'hasExpandedAccess': False}, 'statusVerifiedDate': '2023-07', 'completionDateStruct': {'date': '2020-07-31', 'type': 'ACTUAL'}, 'lastUpdateSubmitDate': '2023-07-30', 'studyFirstSubmitDate': '2020-11-14', 'studyFirstSubmitQcDate': '2020-11-16', 'lastUpdatePostDateStruct': {'date': '2023-08-01', 'type': 'ACTUAL'}, 'studyFirstPostDateStruct': {'date': '2020-11-17', 'type': 'ACTUAL'}, 'primaryCompletionDateStruct': {'date': '2020-07-31', 'type': 'ACTUAL'}}, 'outcomesModule': {'primaryOutcomes': [{'measure': 'SARS-CoV-2 positivity rate (%)', 'timeFrame': '7 years', 'description': 'The SARS-CoV-2 infection was confirmed using the real-time reverse transcriptase polymerase chain reaction of pharyngeal and nasal swab samples, in accordance with the WHO recommendations'}, {'measure': 'COVID-19 related mortality rate (%)', 'timeFrame': '7 years', 'description': 'The COVID-19 related mortality was defined as the termination of isolation due to death.'}]}, 'oversightModule': {'oversightHasDmc': False, 'isFdaRegulatedDrug': False, 'isFdaRegulatedDevice': False}, 'conditionsModule': {'keywords': ['Physical activity'], 'conditions': ['Covid19']}, 'referencesModule': {'references': [{'pmid': '31999307', 'type': 'RESULT', 'citation': 'Phelan AL, Katz R, Gostin LO. The Novel Coronavirus Originating in Wuhan, China: Challenges for Global Health Governance. JAMA. 2020 Feb 25;323(8):709-710. doi: 10.1001/jama.2020.1097. No abstract available.'}, {'pmid': '32191675', 'type': 'RESULT', 'citation': 'Cucinotta D, Vanelli M. WHO Declares COVID-19 a Pandemic. Acta Biomed. 2020 Mar 19;91(1):157-160. doi: 10.23750/abm.v91i1.9397.'}, {'pmid': '32627443', 'type': 'RESULT', 'citation': 'Kim DW, Byeon KH, Kim J, Cho KD, Lee N. The Correlation of Comorbidities on the Mortality in Patients with COVID-19: an Observational Study Based on the Korean National Health Insurance Big Data. J Korean Med Sci. 2020 Jul 6;35(26):e243. doi: 10.3346/jkms.2020.35.e243.'}, {'pmid': '32454138', 'type': 'RESULT', 'citation': 'Hamer M, Kivimaki M, Gale CR, Batty GD. Lifestyle risk factors, inflammatory mechanisms, and COVID-19 hospitalization: A community-based cohort study of 387,109 adults in UK. Brain Behav Immun. 2020 Jul;87:184-187. doi: 10.1016/j.bbi.2020.05.059. Epub 2020 May 23.'}]}, 'descriptionModule': {'briefSummary': 'Coronavirus disease 2019 (COVID-19) is an infectious disease caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). Currently, there is no cure for COVID-19, except for supportive treatments. Quarantine for a defined period is the best option to reduce the spread of COVID-19. Physical activity has been shown to reduce the risk of serious community-acquired infections. However, it remains unanswered is whether physical activity has protective effects against SARS-CoV-2 infection and COVID-19 related mortality. This study aimed to examine the association of PA with the morbidity and mortality of COVID-19 infection in the entire South Korean population.'}, 'eligibilityModule': {'sex': 'ALL', 'stdAges': ['ADULT', 'OLDER_ADULT'], 'minimumAge': '18 Years', 'samplingMethod': 'PROBABILITY_SAMPLE', 'studyPopulation': 'The Korean nationwide COVID-19 study was a retrospective, nationwide study including all Koreans who tested positive for SARS-CoV-2, aimed at evaluating the characteristics and outcomes of patients with COVID-19. Case patients were defined as individuals over 18 years old with positive results for the SARS-CoV-2 test. For every case patient, we selected up to 20 random controls from the target population who underwent the national health screening.', 'healthyVolunteers': False, 'eligibilityCriteria': 'Inclusion Criteria:\n\n* all Koreans who tested positive for SARS-CoV-2\n* more than 18 years old\n* who underwent public health screening between 2014 and 2017\n\nExclusion Criteria:\n\n* missing values about physical activity'}, 'identificationModule': {'nctId': 'NCT04631861', 'briefTitle': 'Physical Activity and the Risk of COVID-19 Infection and Mortality', 'organization': {'class': 'OTHER', 'fullName': 'Wonju Severance Christian Hospital'}, 'officialTitle': 'Physical Activity and the Risk of COVID-19 Infection and Mortality', 'orgStudyIdInfo': {'id': '2020AN0292'}}, 'contactsLocationsModule': {'overallOfficials': [{'name': 'Dong-Hyuk Cho', 'role': 'PRINCIPAL_INVESTIGATOR', 'affiliation': 'Yonsei Wonju Christian Hospital'}]}, 'ipdSharingStatementModule': {'ipdSharing': 'NO', 'description': 'The present study are not publicly accessible due to Korean personal information projection act.'}, 'sponsorCollaboratorsModule': {'leadSponsor': {'name': 'Wonju Severance Christian Hospital', 'class': 'OTHER'}, 'responsibleParty': {'type': 'PRINCIPAL_INVESTIGATOR', 'investigatorTitle': 'Clinical assistant professor', 'investigatorFullName': 'Dong-Hyuk Cho', 'investigatorAffiliation': 'Wonju Severance Christian Hospital'}}}}