Ignite Creation Date:
2025-12-24 @ 3:57 PM
Ignite Modification Date:
2026-01-01 @ 7:47 AM
Study NCT ID:
NCT04937192
Status:
UNKNOWN
Last Update Posted:
2022-10-25
First Post:
2021-06-10
Is NOT Gene Therapy:
True
Has Adverse Events:
False
Brief Title:
SNP-based Prediction of Recurrence Risk in Kidney Stone Patients
Sponsor:
Organization:
Raw JSON
{'hasResults': False, 'derivedSection': {'miscInfoModule': {'versionHolder': '2025-12-24'}, 'conditionBrowseModule': {'meshes': [{'id': 'D007669', 'term': 'Kidney Calculi'}, {'id': 'D012008', 'term': 'Recurrence'}], 'ancestors': [{'id': 'D053040', 'term': 'Nephrolithiasis'}, {'id': 'D007674', 'term': 'Kidney Diseases'}, {'id': 'D014570', 'term': 'Urologic Diseases'}, {'id': 'D052776', 'term': 'Female Urogenital Diseases'}, {'id': 'D005261', 'term': 'Female Urogenital Diseases and Pregnancy Complications'}, {'id': 'D000091642', 'term': 'Urogenital Diseases'}, {'id': 'D052878', 'term': 'Urolithiasis'}, {'id': 'D014545', 'term': 'Urinary Calculi'}, {'id': 'D052801', 'term': 'Male Urogenital Diseases'}, {'id': 'D002137', 'term': 'Calculi'}, {'id': 'D020763', 'term': 'Pathological Conditions, Anatomical'}, {'id': 'D013568', 'term': 'Pathological Conditions, Signs and Symptoms'}, {'id': 'D020969', 'term': 'Disease Attributes'}, {'id': 'D010335', 'term': 'Pathologic Processes'}]}}, 'protocolSection': {'designModule': {'bioSpec': {'retention': 'SAMPLES_WITH_DNA', 'description': 'Blood was obtained for DNA'}, 'studyType': 'OBSERVATIONAL', 'designInfo': {'timePerspective': 'PROSPECTIVE', 'observationalModel': 'COHORT'}, 'enrollmentInfo': {'type': 'ESTIMATED', 'count': 1300}, 'patientRegistry': False}, 'statusModule': {'overallStatus': 'UNKNOWN', 'lastKnownStatus': 'RECRUITING', 'startDateStruct': {'date': '2012-01-01', 'type': 'ACTUAL'}, 'expandedAccessInfo': {'hasExpandedAccess': False}, 'statusVerifiedDate': '2022-10', 'completionDateStruct': {'date': '2023-12-31', 'type': 'ESTIMATED'}, 'lastUpdateSubmitDate': '2022-10-23', 'studyFirstSubmitDate': '2021-06-10', 'studyFirstSubmitQcDate': '2021-06-15', 'lastUpdatePostDateStruct': {'date': '2022-10-25', 'type': 'ACTUAL'}, 'studyFirstPostDateStruct': {'date': '2021-06-23', 'type': 'ACTUAL'}, 'primaryCompletionDateStruct': {'date': '2022-12-31', 'type': 'ESTIMATED'}}, 'outcomesModule': {'primaryOutcomes': [{'measure': 'Stone-free survival', 'timeFrame': 'From date of stone-free until the date of first stone recurrence (up to 7 years)', 'description': 'Time to first stone recurrence from stone-free'}]}, 'oversightModule': {'oversightHasDmc': False, 'isFdaRegulatedDrug': False, 'isFdaRegulatedDevice': False}, 'conditionsModule': {'keywords': ['SNP', 'Kidney stone', 'Recurrence'], 'conditions': ['Kidney Stone']}, 'descriptionModule': {'briefSummary': 'The goal of this study is to gain new knowledge about genetic risk factors that may affect the kidney stone recurrence. The study seeks to understand if different forms of genes result in an increased risk of kidney stone recurrence.', 'detailedDescription': 'In this study, investigators are prospectively testing whether SNP are associated with kidney stone recurrence. Investigators will test the hypothesis that SNP predispose kidney stone patients to recurrence.\n\nInvestigators hope to identify predictors for the kidney stone recurrence. This would allow the identification of a subpopulation of kidney stone patients that would benefit most from prevention measures.'}, 'eligibilityModule': {'sex': 'ALL', 'stdAges': ['ADULT', 'OLDER_ADULT'], 'minimumAge': '18 Years', 'samplingMethod': 'NON_PROBABILITY_SAMPLE', 'studyPopulation': 'Kidney stone former who the stone was removed completely', 'healthyVolunteers': False, 'eligibilityCriteria': 'Inclusion Criteria:\n\n* Age 18 or older\n* Kidney stone former who the stone was removed completely.\n* Ability to give informed consent\n\nExclusion Criteria:\n\n* Patient refuses or is unable to give consent'}, 'identificationModule': {'nctId': 'NCT04937192', 'briefTitle': 'SNP-based Prediction of Recurrence Risk in Kidney Stone Patients', 'organization': {'class': 'OTHER', 'fullName': 'The First Affiliated Hospital of Guangzhou Medical University'}, 'officialTitle': 'SNP-based Prediction of Recurrence Risk in Kidney Stone Patients: a Prospective Multicenter Observational Study', 'orgStudyIdInfo': {'id': 'MRER2013-001'}}, 'armsInterventionsModule': {'armGroups': [{'label': 'Kidney stone former', 'interventionNames': ['Other: No intervention']}], 'interventions': [{'name': 'No intervention', 'type': 'OTHER', 'description': 'No intervention', 'armGroupLabels': ['Kidney stone former']}]}, 'contactsLocationsModule': {'locations': [{'zip': '510120', 'city': 'Guangzhou', 'state': 'Guangdong', 'status': 'RECRUITING', 'country': 'China', 'contacts': [{'name': 'Guohua Zeng, Ph.D.', 'role': 'CONTACT', 'email': 'gzgyzgh@vip.sina.com', 'phone': '+86 13802916676'}, {'name': 'Guohua Zeng, M.D.', 'role': 'PRINCIPAL_INVESTIGATOR'}, {'name': 'Wei Zhu, Ph.D.', 'role': 'SUB_INVESTIGATOR'}], 'facility': 'The First Affiliated Hospital of Guangzhou Medical University', 'geoPoint': {'lat': 23.11667, 'lon': 113.25}}], 'centralContacts': [{'name': 'Guohua Zeng, M.D.', 'role': 'CONTACT', 'email': 'gzgyzgh@vip.sina.com', 'phone': '13802916676'}, {'name': 'Wei Zhu, M.D.', 'role': 'CONTACT', 'email': 'doczw1989@126.com', 'phone': '13622754991'}], 'overallOfficials': [{'name': 'Guohua Zeng, M.D.', 'role': 'PRINCIPAL_INVESTIGATOR', 'affiliation': 'The First Affiliated Hospital of Guangzhou Medical University'}]}, 'ipdSharingStatementModule': {'ipdSharing': 'UNDECIDED'}, 'sponsorCollaboratorsModule': {'leadSponsor': {'name': 'The First Affiliated Hospital of Guangzhou Medical University', 'class': 'OTHER'}, 'collaborators': [{'name': 'Xiangya Hospital of Central South University', 'class': 'OTHER'}, {'name': 'Wuhan University Renmin Hospital', 'class': 'UNKNOWN'}, {'name': 'The Second Affiliated Hospital of Kunming Medical University', 'class': 'OTHER'}, {'name': 'Tianjin Medical University Second Hospital', 'class': 'OTHER'}, {'name': "Shenzhen People's Hospital", 'class': 'OTHER'}, {'name': '301 Hospital', 'class': 'UNKNOWN'}, {'name': 'Zhongda Hospital', 'class': 'OTHER'}, {'name': "People's Hospital of Xinjiang", 'class': 'UNKNOWN'}, {'name': 'ZhuZhou Central Hospital', 'class': 'OTHER'}, {'name': "Baoshan No.2 People's Hospital", 'class': 'UNKNOWN'}, {'name': "Guangdong No.2 People's Hospital", 'class': 'UNKNOWN'}, {'name': "Dehong People's Hospital", 'class': 'UNKNOWN'}, {'name': 'Second Affiliated Hospital of Guangzhou Medical University', 'class': 'OTHER'}, {'name': 'Jiangmen Central Hospital', 'class': 'OTHER'}, {'name': 'Huizhou Municipal Central Hospital', 'class': 'OTHER'}, {'name': 'Yongzhou Center Hospital', 'class': 'UNKNOWN'}, {'name': "Longgang District People's Hospital of Shenzhen", 'class': 'OTHER'}], 'responsibleParty': {'type': 'PRINCIPAL_INVESTIGATOR', 'investigatorTitle': 'Vice president', 'investigatorFullName': 'Guohua Zeng', 'investigatorAffiliation': 'The First Affiliated Hospital of Guangzhou Medical University'}}}}