Ignite Creation Date:
2025-12-24 @ 3:43 PM
Ignite Modification Date:
2026-02-25 @ 1:54 AM
Study NCT ID:
NCT06610292
Status:
COMPLETED
Last Update Posted:
2024-09-24
First Post:
2024-09-17
Is NOT Gene Therapy:
True
Has Adverse Events:
False
Brief Title:
Effects of Pharmacist-led Medication Reconciliation Services on Geriatric Patients
Sponsor:
Organization:
Raw JSON
{'hasResults': False, 'derivedSection': {'miscInfoModule': {'versionHolder': '2025-12-24'}}, 'protocolSection': {'designModule': {'phases': ['NA'], 'studyType': 'INTERVENTIONAL', 'designInfo': {'allocation': 'RANDOMIZED', 'maskingInfo': {'masking': 'SINGLE', 'whoMasked': ['CARE_PROVIDER']}, 'primaryPurpose': 'HEALTH_SERVICES_RESEARCH', 'interventionModel': 'PARALLEL'}, 'enrollmentInfo': {'type': 'ACTUAL', 'count': 128}}, 'statusModule': {'overallStatus': 'COMPLETED', 'startDateStruct': {'date': '2018-06-24', 'type': 'ACTUAL'}, 'expandedAccessInfo': {'hasExpandedAccess': False}, 'statusVerifiedDate': '2024-09', 'completionDateStruct': {'date': '2018-10-13', 'type': 'ACTUAL'}, 'lastUpdateSubmitDate': '2024-09-19', 'studyFirstSubmitDate': '2024-09-17', 'studyFirstSubmitQcDate': '2024-09-19', 'lastUpdatePostDateStruct': {'date': '2024-09-24', 'type': 'ACTUAL'}, 'studyFirstPostDateStruct': {'date': '2024-09-24', 'type': 'ACTUAL'}, 'primaryCompletionDateStruct': {'date': '2018-10-13', 'type': 'ACTUAL'}}, 'outcomesModule': {'primaryOutcomes': [{'measure': 'Describing prevalence and nature of medication discrepancies in elderly patients and investigating contributing factors to medication discrepancies.', 'timeFrame': 'Up to 20 weeks', 'description': 'Linear regression analysis was performed to assess risk factors associated with the occurrence of medication discrepancies in elderly patients.'}, {'measure': 'Analysis of the effects of Pharmacist-led medication reconciliation services on resolving medication discrepancies upon discharge', 'timeFrame': 'Up to 16 weeks', 'description': 'Number of resolved medication discrepancies was documented upon discharge after providing pharmacist-led medication reconciliation services.'}, {'measure': 'Evaluating the impacts of Pharmacist-led medication reconciliation services on hospital re-admissions within 30 days of discharge', 'timeFrame': 'Up to 20 weeks', 'description': 'Elderly patients were assessed for number of hospital re-admissions within 30 days of discharge at control and intervention groups.'}, {'measure': 'Evaluating the impacts of Pharmacist-led medication reconciliation services on emergency department visits within 30 days of discharge', 'timeFrame': 'Up to 20 weeks', 'description': 'Elderly patients were assessed for number of emergency department visits within 30 days of discharge at control and intervention groups.'}, {'measure': 'Evaluating the impacts of Pharmacist-led medication reconciliation services on medications side effects within 30 days of discharge', 'timeFrame': 'Up to 20 weeks', 'description': 'Elderly patients were assessed for incidence of medications side effects within 30 days of discharge at control and intervention groups.'}]}, 'oversightModule': {'isUsExport': False, 'oversightHasDmc': False, 'isFdaRegulatedDrug': False, 'isFdaRegulatedDevice': False}, 'conditionsModule': {'keywords': ['Medication reconciliation', 'Geriatrics', 'Geriatric patients', 'Jordan', 'Tertiary military hospital', 'Pharmacist-led medication reconciliation'], 'conditions': ['Geriatric Patients', 'Medication Reconcilitation Upon Hospital Admission', 'Medication Reconciliation At Discharge', 'Pharmacist-led Medication Reconciliation']}, 'descriptionModule': {'briefSummary': 'This study aims to assess the effects of Pharmacist-led medication reconciliation on hospitalized elderly patients aged above 65 at a leading tertiary military hospital in Jordan.', 'detailedDescription': 'A four-month randomized controlled trial was conducted at King Hussein Medical Hospital (KHMH), one of the Royal Military Medical Services (RMS) tertiary hospitals located in central Amman. During the study period, 128 patients were selected using convenience sampling. Later, medication histories were compared between pre-admission and admission records to obtain the Best Possible Medication History (BPMH) and identify medication discrepancies, which were categorized as either intentional (documentation errors) or unintentional discrepancies.\n\nThe already selected patients were randomly allocated into two groups (intervention and control groups). Then, Pharmacist-led medication reconciliation services were provided to the intervention group and standard care was provided to the control group. Also at discharge the number of medication discrepancies was documented. Linear regression analysis was performed to assess risk factors associated with the occurrence of unintentional discrepancies.\n\nWithin 30 days post-discharge, patients were assessed for any hospital re-admissions, emergency department visits and medication-related side effects.'}, 'eligibilityModule': {'sex': 'ALL', 'stdAges': ['OLDER_ADULT'], 'minimumAge': '65 Years', 'healthyVolunteers': False, 'eligibilityCriteria': 'Inclusion Criteria:\n\n* Newly admitted patient within no more than 24 hours and anticipated to stay in the hospital for more than 48 hours.\n* Geriatrics patients defined as those aged (≥65 years) (Orimo et al., 2006).\n* Prescribed at least one chronic medication prior to the study admission.\n\nExclusion Criteria:\n\n* Patient admitted to the critical care or isolation units or in unconscious or comatose states.\n* Patients if they were discharged against medical advice.'}, 'identificationModule': {'nctId': 'NCT06610292', 'briefTitle': 'Effects of Pharmacist-led Medication Reconciliation Services on Geriatric Patients', 'organization': {'class': 'OTHER', 'fullName': 'University of Jordan'}, 'officialTitle': 'Effects of Pharmacist-led Medication Reconciliation Services on Geriatric Patients At a Leading Military Hospital in Jordan', 'orgStudyIdInfo': {'id': '6/2018'}}, 'armsInterventionsModule': {'armGroups': [{'type': 'NO_INTERVENTION', 'label': 'Control group', 'description': 'Patients did not receive Pharmacist-led medication reconciliation services'}, {'type': 'EXPERIMENTAL', 'label': 'Intervention group', 'description': 'Patients received Pharmacist-led medication reconciliation services', 'interventionNames': ['Other: Pharmacist-led medication reconciliation services']}], 'interventions': [{'name': 'Pharmacist-led medication reconciliation services', 'type': 'OTHER', 'description': 'Upon admission, information about patients Best Possible Medication History (BPMH) was extracted. Information on current medications, both regular and as-needed, was also recorded. All data were cross-referenced with the electronic records and verified through patients or caregivers interviews to create a comprehensive medication list.\n\nThen, comparison was conducted between standard care medication list and Pharmacist-led medication reconciliation list to identify any possible medication discrepancies. Also, during hospital stay and upon discharge emerging medication discrepancies were assessed and resolved.\n\nMoreover, the impacts on healthcare resources utilization within 30 days post-discharge was measured. This includes evaluating hospital re-admissions, emergency department visits, and the occurrence of any adverse drug events (ADEs).', 'armGroupLabels': ['Intervention group']}]}, 'contactsLocationsModule': {'locations': [{'city': 'Amman', 'country': 'Jordan', 'facility': 'University of Jordan', 'geoPoint': {'lat': 31.95522, 'lon': 35.94503}}], 'overallOfficials': [{'name': 'Eman A Hammad', 'role': 'PRINCIPAL_INVESTIGATOR', 'affiliation': 'Department of Biopharmaceutics and Clinical Pharmacy, School of Pharmacy, University of Jordan'}]}, 'ipdSharingStatementModule': {'ipdSharing': 'NO'}, 'sponsorCollaboratorsModule': {'leadSponsor': {'name': 'University of Jordan', 'class': 'OTHER'}, 'collaborators': [{'name': 'Jordanian Royal Medical Services', 'class': 'OTHER'}, {'name': 'Royal Medical Services, Jordanian Armed Forces', 'class': 'OTHER'}], 'responsibleParty': {'type': 'PRINCIPAL_INVESTIGATOR', 'investigatorTitle': 'Research Assistant', 'investigatorFullName': 'Majed Shafaamri', 'investigatorAffiliation': 'University of Jordan'}}}}