Ignite Creation Date:
2025-12-24 @ 3:38 PM
Ignite Modification Date:
2026-02-26 @ 7:47 PM
Study NCT ID:
NCT07005492
Status:
COMPLETED
Last Update Posted:
2025-06-05
First Post:
2025-01-13
Is NOT Gene Therapy:
True
Has Adverse Events:
False
Brief Title:
Factors Affecting Success and Survival Rates in Root Canal Retreatment
Sponsor:
Organization:
Raw JSON
{'hasResults': False, 'derivedSection': {'miscInfoModule': {'versionHolder': '2025-12-24'}, 'interventionBrowseModule': {'meshes': [{'id': 'D010808', 'term': 'Physical Examination'}], 'ancestors': [{'id': 'D019937', 'term': 'Diagnostic Techniques and Procedures'}, {'id': 'D003933', 'term': 'Diagnosis'}]}}, 'protocolSection': {'designModule': {'phases': ['NA'], 'studyType': 'INTERVENTIONAL', 'designInfo': {'allocation': 'NA', 'maskingInfo': {'masking': 'NONE'}, 'primaryPurpose': 'DIAGNOSTIC', 'interventionModel': 'SINGLE_GROUP'}, 'enrollmentInfo': {'type': 'ACTUAL', 'count': 408}}, 'statusModule': {'overallStatus': 'COMPLETED', 'startDateStruct': {'date': '2023-06-01', 'type': 'ACTUAL'}, 'expandedAccessInfo': {'hasExpandedAccess': False}, 'statusVerifiedDate': '2025-01', 'completionDateStruct': {'date': '2024-03-01', 'type': 'ACTUAL'}, 'lastUpdateSubmitDate': '2025-06-04', 'studyFirstSubmitDate': '2025-01-13', 'studyFirstSubmitQcDate': '2025-06-04', 'lastUpdatePostDateStruct': {'date': '2025-06-05', 'type': 'ACTUAL'}, 'studyFirstPostDateStruct': {'date': '2025-06-05', 'type': 'ACTUAL'}, 'primaryCompletionDateStruct': {'date': '2023-06-01', 'type': 'ACTUAL'}}, 'outcomesModule': {'primaryOutcomes': [{'measure': 'Survival rate', 'timeFrame': '78.47 ± 10.48 months after treatment', 'description': 'Survival Rate:\n\nSurvival was assessed whether the tooth was in the mouth or not. Survival was scored positive if the tooth was in the mouth, regardless of the health status of the tooth in the clinical and radiological examination at the follow-up appointment.'}, {'measure': 'Success rate', 'timeFrame': '78.47 +10.48 months', 'description': 'Success Rate:\n\nScored as successful or unsuccessful according to the following effects according to the clinical and radiological examinations; restoration status, health of the periapical tissues, presence of swelling and/or the sinus tract.\n\nSuccess: The tooth had no clinical signs or symptoms, and the radiographs revealed complete resolution of periapical lesion Failure: The size of the periapical lesion was unchanged or increased or not completely healed, with or without clinical signs or symptoms'}]}, 'oversightModule': {'isUsExport': False, 'oversightHasDmc': False, 'isFdaRegulatedDrug': False, 'isFdaRegulatedDevice': False}, 'conditionsModule': {'keywords': ['root canal retreatment', 'non-surgical root canal treatment', 'survival', 'success'], 'conditions': ['Root Canal Therapy', 'Root Canal Retreatment']}, 'descriptionModule': {'briefSummary': 'The aim of this study is to evaluate the effects of pre-treatment and procedural factors on survival and success rates in teeth that underwent non-surgical root canal retreatment at Trakya University, Faculty of Dentistry between 2015-2017.\n\nPre-treatment factors examined:\n\n* Age\n* Gender\n* Presence and size of periapical lesion\n* Quality of root canal obturation\n\nFactors examined during treatment:\n\n* Type of restoration\n* Status of restoration at recall\n\nThe null hypothesis was that these factors have no effect on survival and success rate.', 'detailedDescription': 'Patients with teeth that had undergone non-surgical recurrent root canal treatment at Trakya University, Faculty of Dentistry between 2015-2017 were invited for examination. Clinical and radiological examinations were performed on patients who agreed to participate in the study. No additional interventional procedures were performed. As a result of radiological and clinical examinations, whether the tooth was in the mouth, its clinical and radiological health, current clinical symptoms, etc. were determined.'}, 'eligibilityModule': {'sex': 'ALL', 'stdAges': ['ADULT', 'OLDER_ADULT'], 'minimumAge': '18 Years', 'healthyVolunteers': True, 'eligibilityCriteria': 'Inclusion Criterias:\n\n* At least 18 years old at the time of treatment\n* Systemically healthy (ASA 1-2)\n* Acceptable obturation quality after treatment\n\nExclusion Criterias:\n\n* Precense of seperated instrument before or after treatment\n* Precense of perforation before or after treatment\n* Apical surgery before of before or after treatment\n* Immature root development\n* Two adjacent teeth which required root canal treatment or treatment\n* Pregnant women'}, 'identificationModule': {'nctId': 'NCT07005492', 'briefTitle': 'Factors Affecting Success and Survival Rates in Root Canal Retreatment', 'organization': {'class': 'OTHER', 'fullName': 'Trakya University'}, 'officialTitle': 'Factors Affecting Success and Survival Rates in Root Canal Retreatment', 'orgStudyIdInfo': {'id': 'TUTF-2023\\228'}}, 'armsInterventionsModule': {'armGroups': [{'type': 'OTHER', 'label': 'Radiological and clinical examination', 'description': 'The patients were examined radiologically and clinically.', 'interventionNames': ['Diagnostic Test: radiological and clinical examination']}], 'interventions': [{'name': 'radiological and clinical examination', 'type': 'DIAGNOSTIC_TEST', 'description': 'Standard radiological (periapical radiography) and clinical (inspection, percussion, palpation tests etc.) examinations were performed.', 'armGroupLabels': ['Radiological and clinical examination']}]}, 'contactsLocationsModule': {'locations': [{'zip': '22061', 'city': 'Edirne', 'state': 'Merkez', 'country': 'Turkey (Türkiye)', 'facility': 'Trakya University, Faculty of Dentistry', 'geoPoint': {'lat': 41.67719, 'lon': 26.55597}}], 'overallOfficials': [{'name': 'Burhan Can Çanakçş, Associate professor', 'role': 'STUDY_DIRECTOR', 'affiliation': 'Trakya University, Faculty of Dentistry, Department of Endodontics'}]}, 'ipdSharingStatementModule': {'ipdSharing': 'NO'}, 'sponsorCollaboratorsModule': {'leadSponsor': {'name': 'Trakya University', 'class': 'OTHER'}, 'responsibleParty': {'type': 'PRINCIPAL_INVESTIGATOR', 'investigatorTitle': 'Associate Professor', 'investigatorFullName': 'Burhan Can Çanakçi', 'investigatorAffiliation': 'Trakya University'}}}}