Ignite Creation Date:
2026-03-26 @ 3:20 PM
Ignite Modification Date:
2026-03-31 @ 11:40 AM
Study NCT ID:
NCT07320118
Status:
RECRUITING
Last Update Posted:
2026-01-08
First Post:
2025-12-21
Is NOT Gene Therapy:
True
Has Adverse Events:
False
Brief Title:
Does Surgical Treatment of Cartilage Defects Prevent Osteoarthritis in Later Life?
Sponsor:
Organization:
Raw JSON
{'hasResults': False, 'derivedSection': {'miscInfoModule': {'versionHolder': '2026-03-25'}, 'conditionBrowseModule': {'meshes': [{'id': 'D010003', 'term': 'Osteoarthritis'}], 'ancestors': [{'id': 'D001168', 'term': 'Arthritis'}, {'id': 'D007592', 'term': 'Joint Diseases'}, {'id': 'D009140', 'term': 'Musculoskeletal Diseases'}, {'id': 'D012216', 'term': 'Rheumatic Diseases'}]}}, 'protocolSection': {'designModule': {'studyType': 'OBSERVATIONAL', 'designInfo': {'timePerspective': 'PROSPECTIVE', 'observationalModel': 'CASE_CONTROL'}, 'enrollmentInfo': {'type': 'ESTIMATED', 'count': 650}, 'patientRegistry': False}, 'statusModule': {'overallStatus': 'RECRUITING', 'startDateStruct': {'date': '2010-04-13', 'type': 'ACTUAL'}, 'expandedAccessInfo': {'hasExpandedAccess': False}, 'statusVerifiedDate': '2025-12', 'completionDateStruct': {'date': '2030-01-12', 'type': 'ESTIMATED'}, 'lastUpdateSubmitDate': '2026-01-06', 'studyFirstSubmitDate': '2025-12-21', 'studyFirstSubmitQcDate': '2025-12-21', 'lastUpdatePostDateStruct': {'date': '2026-01-08', 'type': 'ACTUAL'}, 'studyFirstPostDateStruct': {'date': '2026-01-06', 'type': 'ACTUAL'}, 'primaryCompletionDateStruct': {'date': '2030-01-12', 'type': 'ESTIMATED'}}, 'outcomesModule': {'primaryOutcomes': [{'measure': 'Cell Therapy Questionnaire', 'timeFrame': 'At least fifteen months post operation', 'description': 'Cell Therapy Questionnaire CTQ'}]}, 'oversightModule': {'oversightHasDmc': False, 'isFdaRegulatedDrug': False, 'isFdaRegulatedDevice': False}, 'conditionsModule': {'conditions': ['Osteoarthritis (OA)']}, 'descriptionModule': {'briefSummary': 'Observational study to assess the effectiveness of cell therapy for the treatment of osteoarthritis'}, 'eligibilityModule': {'sex': 'ALL', 'stdAges': ['CHILD', 'ADULT', 'OLDER_ADULT'], 'samplingMethod': 'NON_PROBABILITY_SAMPLE', 'studyPopulation': 'Patients based in the United Kingdom treated at RJAH orthopaedic hospital', 'healthyVolunteers': False, 'eligibilityCriteria': 'Inclusion Criteria:\n\n* ACI patients or patients receiving an alternative treatment\n\nExclusion Criteria:\n\n* Anyone who does not meet the inclusion criteria'}, 'identificationModule': {'nctId': 'NCT07320118', 'acronym': 'REACT', 'briefTitle': 'Does Surgical Treatment of Cartilage Defects Prevent Osteoarthritis in Later Life?', 'organization': {'class': 'OTHER_GOV', 'fullName': 'Robert Jones and Agnes Hunt Orthopaedic and District NHS Trust'}, 'officialTitle': 'Cell Therapy for Osteoarthritis', 'orgStudyIdInfo': {'id': 'RL1 418'}}, 'armsInterventionsModule': {'armGroups': [{'label': 'ACI patiients', 'description': 'Patient must have had ACI surgery at least 10 months prior'}, {'label': 'Non ACI Patients', 'description': 'Control group of patients who did not have ACI'}]}, 'contactsLocationsModule': {'locations': [{'zip': 'Sy10 7AG', 'city': 'Oswestry', 'status': 'RECRUITING', 'country': 'United Kingdom', 'contacts': [{'name': 'Karina Wright', 'role': 'CONTACT', 'email': 'karina.wright1@nhs.net', 'phone': '+441691404022'}, {'name': 'Wright', 'role': 'CONTACT'}], 'facility': 'The Robert Jones and Agnes Hunt Orthopaedic Hospital', 'geoPoint': {'lat': 52.86195, 'lon': -3.05497}}, {'city': 'Oswestry', 'status': 'RECRUITING', 'country': 'United Kingdom', 'contacts': [{'name': 'Wright', 'role': 'CONTACT', 'email': 'karina.wright1@nhs.net', 'phone': '+441691404022'}], 'facility': 'Robert Jones and Agnes Hunt Orthopaedic hospital', 'geoPoint': {'lat': 52.86195, 'lon': -3.05497}}]}, 'sponsorCollaboratorsModule': {'leadSponsor': {'name': 'Robert Jones and Agnes Hunt Orthopaedic and District NHS Trust', 'class': 'OTHER_GOV'}, 'collaborators': [{'name': 'Keele University', 'class': 'OTHER'}], 'responsibleParty': {'type': 'SPONSOR'}}}}