Ignite Creation Date:
2026-03-26 @ 3:18 PM
Ignite Modification Date:
2026-03-30 @ 2:57 AM
Study NCT ID:
NCT07493694
Status:
NOT_YET_RECRUITING
Last Update Posted:
2026-03-25
First Post:
2026-03-05
Is NOT Gene Therapy:
True
Has Adverse Events:
False
Brief Title:
Clinico-radiological Correlations in Cerebro-VASCULAR Disease
Sponsor:
Organization:
Raw JSON
{'hasResults': False, 'derivedSection': {'miscInfoModule': {'versionHolder': '2026-03-25'}}, 'protocolSection': {'designModule': {'studyType': 'OBSERVATIONAL', 'designInfo': {'timePerspective': 'OTHER', 'observationalModel': 'OTHER'}, 'enrollmentInfo': {'type': 'ESTIMATED', 'count': 1143}, 'targetDuration': '20 Years', 'patientRegistry': True}, 'statusModule': {'overallStatus': 'NOT_YET_RECRUITING', 'startDateStruct': {'date': '2026-04', 'type': 'ESTIMATED'}, 'expandedAccessInfo': {'hasExpandedAccess': False}, 'statusVerifiedDate': '2026-03', 'completionDateStruct': {'date': '2046-04', 'type': 'ESTIMATED'}, 'lastUpdateSubmitDate': '2026-03-20', 'studyFirstSubmitDate': '2026-03-05', 'studyFirstSubmitQcDate': '2026-03-20', 'lastUpdatePostDateStruct': {'date': '2026-03-25', 'type': 'ACTUAL'}, 'studyFirstPostDateStruct': {'date': '2026-03-25', 'type': 'ACTUAL'}, 'primaryCompletionDateStruct': {'date': '2046-04', 'type': 'ESTIMATED'}}, 'outcomesModule': {'primaryOutcomes': [{'measure': 'Epidemiological patterns, clinical profiles, and diagnostic imaging trends in cerebrovascular disease', 'timeFrame': 'Baseline (at diagnosis), up to 20 years', 'description': 'Primary Outcome Measure:\n\nDiagnostic imaging trends in cerebrovascular disease Description: Key imaging findings from first MRI/CT (e.g., lesion location, vessel involvement; %).'}]}, 'oversightModule': {'oversightHasDmc': False, 'isFdaRegulatedDrug': False, 'isFdaRegulatedDevice': False}, 'conditionsModule': {'conditions': ['Cerebro Vascular Disease']}, 'descriptionModule': {'briefSummary': 'This observational retrospective and prospective registry aims to explore the relationships between clinical manifestations and radiological findings in cerebrovascular diseases. These conditions are characterized by heterogeneous radiological presentations and different etiologies, posing challenges for accurate diagnosis and effective treatment. Understanding these correlations is essential for advancing diagnostic accuracy and therapeutic strategies.'}, 'eligibilityModule': {'sex': 'ALL', 'stdAges': ['ADULT', 'OLDER_ADULT'], 'maximumAge': '100 Years', 'minimumAge': '18 Years', 'samplingMethod': 'NON_PROBABILITY_SAMPLE', 'studyPopulation': 'The registry will focus on adults aged 18 to 100 of both genders diagnosed with various cerebrovascular diseases based on clinical and imaging evaluations. Participants will be selected from a retrospective registry of patients who have undergone MRI or CT scans for clinical indications. In addition to the retrospective cohort, the registry will also include a prospective component, enrolling newly diagnosed patients who meet the same eligibility criteria.', 'healthyVolunteers': False, 'eligibilityCriteria': 'Inclusion Criteria:\n\n* Age Range: 18-100 years old.\n* Must have undergone a CT or MRI scan of the central nervous system (CNS) (for clinical reasons).\n\nExclusion Criteria:\n\n* Alternative diagnosis to vascular pathology that explains clinical symptoms.\n* MRI or CT non-diagnostic or non-evaluable MRI due to motion artifacts.'}, 'identificationModule': {'nctId': 'NCT07493694', 'briefTitle': 'Clinico-radiological Correlations in Cerebro-VASCULAR Disease', 'organization': {'class': 'OTHER', 'fullName': 'IRCCS San Raffaele'}, 'officialTitle': 'Clinico-radiological Correlations in Cerebro-VASCULAR Disease: Toward a BetteR understAndINg of Their Heterogeneous Manifestations in a Retrospective and Prospective Observational Registry', 'orgStudyIdInfo': {'id': 'VASCULAR-BRAIN'}}, 'ipdSharingStatementModule': {'ipdSharing': 'NO'}, 'sponsorCollaboratorsModule': {'leadSponsor': {'name': 'IRCCS San Raffaele', 'class': 'OTHER'}, 'responsibleParty': {'type': 'PRINCIPAL_INVESTIGATOR', 'investigatorTitle': 'Principal investigator', 'investigatorFullName': 'Anna del Poggio', 'investigatorAffiliation': 'IRCCS San Raffaele'}}}}