Ignite Creation Date:
2026-03-26 @ 3:18 PM
Ignite Modification Date:
2026-03-31 @ 4:01 AM
Study NCT ID:
NCT07382167
Status:
RECRUITING
Last Update Posted:
2026-03-17
First Post:
2026-01-26
Is NOT Gene Therapy:
True
Has Adverse Events:
False
Brief Title:
A 26-Wk Study to Assess Safety & Efficacy of Tenapanor for T/t of Chronic Idiopathic Constipation in Adults
Sponsor:
Organization:
Raw JSON
{'hasResults': False, 'derivedSection': {'miscInfoModule': {'versionHolder': '2026-03-25'}, 'interventionBrowseModule': {'meshes': [{'id': 'C000599417', 'term': 'tenapanor'}, {'id': 'C494814', 'term': 'BID protein, human'}]}}, 'protocolSection': {'designModule': {'phases': ['PHASE3'], 'studyType': 'INTERVENTIONAL', 'designInfo': {'allocation': 'RANDOMIZED', 'maskingInfo': {'masking': 'QUADRUPLE', 'whoMasked': ['PARTICIPANT', 'CARE_PROVIDER', 'INVESTIGATOR', 'OUTCOMES_ASSESSOR']}, 'primaryPurpose': 'TREATMENT', 'interventionModel': 'PARALLEL'}, 'enrollmentInfo': {'type': 'ESTIMATED', 'count': 692}}, 'statusModule': {'overallStatus': 'RECRUITING', 'startDateStruct': {'date': '2026-01-13', 'type': 'ACTUAL'}, 'expandedAccessInfo': {'hasExpandedAccess': False}, 'statusVerifiedDate': '2026-03', 'completionDateStruct': {'date': '2027-06-04', 'type': 'ESTIMATED'}, 'lastUpdateSubmitDate': '2026-03-13', 'studyFirstSubmitDate': '2026-01-26', 'studyFirstSubmitQcDate': '2026-01-26', 'lastUpdatePostDateStruct': {'date': '2026-03-17', 'type': 'ACTUAL'}, 'studyFirstPostDateStruct': {'date': '2026-02-02', 'type': 'ACTUAL'}, 'primaryCompletionDateStruct': {'date': '2027-02-26', 'type': 'ESTIMATED'}}, 'outcomesModule': {'primaryOutcomes': [{'measure': 'Durable complete spontaneous bowel movements (CSBM) response', 'timeFrame': '12 Weeks', 'description': 'Durable complete spontaneous bowel movements (CSBM) response is defined as achieving the weekly CSBM response for ≥9 out of the first 12 weeks of the randomized treatment period and and for ≥3 of the last 4 weeks of the first 12 weeks of randomized treatment period'}], 'secondaryOutcomes': [{'measure': '9/12 week complete spontaneous bowel movements (CSBM) response', 'timeFrame': '12 Weeks', 'description': '9/12 week complete spontaneous bowel movements (CSBM) response defined as achieving the weekly CSBM response for ≥9 out of the first 12 weeks of the randomized treatment period.'}, {'measure': 'Change from baseline in complete spontaneous bowel movements (CSBM) frequency', 'timeFrame': '12 Weeks', 'description': 'Change from baseline over the first 12 weeks of the randomized treatment period in complete spontaneous bowel movements (CSBM) frequency'}, {'measure': 'Change from baseline in spontaneous bowel movement (SBM) frequency', 'timeFrame': '12 Weeks', 'description': 'Change from baseline over the first 12 weeks of the randomized treatment period in spontaneous bowel movement (SBM) frequency'}, {'measure': 'Change from baseline in stool consistency', 'timeFrame': '12 Weeks', 'description': 'Change from baseline over the first 12 weeks of the randomized treatment period in stool consistency'}, {'measure': 'Change from baseline in stool straining', 'timeFrame': '12 Weeks', 'description': 'Change from baseline over the first 12 weeks of the randomized treatment period in straining'}]}, 'oversightModule': {'oversightHasDmc': False, 'isFdaRegulatedDrug': True, 'isFdaRegulatedDevice': False}, 'conditionsModule': {'keywords': ['CIC'], 'conditions': ['Chronic Idiopathic Constipation (CIC)']}, 'descriptionModule': {'briefSummary': 'This is a 26-week, multi-center, randomized, double-blind, placebo-controlled study with a 4-week treatment-free Safety Follow-up period to assess the safety and efficacy of tenapanor (5 mg, 25mg, and 50 mg) in adult patients with Chronic Idiopathic Constipation (CIC) when administered twice daily for 26 consecutive weeks.', 'detailedDescription': 'This study consists of a 2-week Screening period, followed by a 26-week randomized treatment period (RTP), and a 4-week treatment-free Safety Follow-up period.\n\nAfter obtaining study informed consent from patients, the 2-week Screening period starts. Patients will be fully assessed for eligibility into the study. The assessments will include evaluation of inclusion/exclusion criteria, including medical histories, physical examination, vital signs, 12-lead electrocardiogram (ECG), and clinical laboratory tests.\n\nPatients will also self-report, on information about the status of their constipation symptoms and severity via an electronic diary (eDiary). Patient compliance with the eDiary will be monitored to determine eligibility at the end of screening.\n\nEligible patients will be randomized (Visit 2) to receive tenapanor 5 mg BID (twice a day), 25 mg BID, 50 mg BID, or placebo for 26 consecutive weeks as the double-blind RTP. During this period, patients will continue recording daily assessments of constipation symptoms and weekly assessments of constipation severity in the eDiary. Patients will have return visits every two to six weeks at Weeks 2, 4, 8, 12, 16, 20 and 26(Visit 3-9) to undergo safety assessments.\n\nUpon completion of the 26-week RTP, patients will be monitored for AEs (adverse events) during the 4-week treatment-free Safety Follow-up period and complete the Follow-up visit (Visit 10) at the end of this period to undergo safety assessments.'}, 'eligibilityModule': {'sex': 'ALL', 'stdAges': ['ADULT', 'OLDER_ADULT'], 'maximumAge': '80 Years', 'minimumAge': '18 Years', 'healthyVolunteers': False, 'eligibilityCriteria': "Inclusion Criteria:\n\n1. Patients ≥18 to ≤80 years old at the Screening visit (Visit 1).\n2. Meet the Rome IV Diagnostic Criteria for functional constipation.\n3. Females of non-childbearing potential, or agree to the use of an acceptable means of contraception for up to 30 days following the last dose of study medication.\n4. Males must agree to use an appropriate method of barrier contraception or have documented surgical sterilization.\n5. Meets the entry criteria assessed during the Screening period.\n6. Ability to understand and provide input on the assessments in the eDiary.\n7. Provide written informed consent before the initiation of any study-specific procedures.\n8. Must agree to have daily access to eDiary via a computer, tablet or smart phone\n\nExclusion Criteria:\n\n1. Loose or watery stool in the absence of any medication that is known to affect stool consistency for \\>25% of bowel movements (BMs) during the 3 months prior to the Screening visit\n2. Fecal impaction within 6 months prior to the Screening visit\n3. Unexplained and clinically significant alarm symptoms.\n4. Functional diarrhea as defined by Rome IV criteria\n5. IBS with constipation (IBS-C), IBS with diarrhea (IBS-D), mixed IBS (IBS-M), or unsubtyped IBS as defined by Rome IV criteria\n6. Diagnosis or treatment of any clinically symptomatic abnormality of the GI tract or active disease within 6 months prior to the Screening visit\n7. Patient with central nervous system disorder\n8. Use of prohibited medications defined by protocol\n9. Patient has a history or current evidence of laxative abuse\n10. Hepatic dysfunction\n11. Positive HIV, hepatitis B or hepatitis C test at screening\n12. Positive urinary drug test at Screening, with the exception of cannabis and cannabidiol (CBD)\n13. Any evidence of or treatment of malignancy within 1 year prior to the Screening visit\n14. Any surgery on the stomach, small intestine or colon; appendectomy or cholecystectomy are not excluded unless within 60 days prior to the Screening visit\n15. Pregnant women or women planning to become pregnant during trial participation\n16. A major psychiatric disorder that has required hospitalization in the last year prior to the Screening visit.\n17. Alcohol or substance abuse within 1 year prior to the Screening visit\n18. Participation in other clinical trials within 1 month prior to the Screening visit\n19. Clinical evidence of significant disease that may interfere with the patient's successful completion of the trial"}, 'identificationModule': {'nctId': 'NCT07382167', 'briefTitle': 'A 26-Wk Study to Assess Safety & Efficacy of Tenapanor for T/t of Chronic Idiopathic Constipation in Adults', 'organization': {'class': 'INDUSTRY', 'fullName': 'Ardelyx'}, 'officialTitle': 'A 26-Week, Multi-Center, Randomized, Double-Blind, Placebo-Controlled Study to Assess the Safety and Efficacy of Tenapanor for the Treatment of Chronic Idiopathic Constipation (CIC) in Adults', 'orgStudyIdInfo': {'id': 'TEN-03-301'}}, 'armsInterventionsModule': {'armGroups': [{'type': 'EXPERIMENTAL', 'label': 'Tenapanor 5 mg BID', 'description': 'Patients will be randomized to receive 5 mg tenapanor twice daily.', 'interventionNames': ['Drug: Tenapanor 5 mg BID']}, {'type': 'EXPERIMENTAL', 'label': 'Tenapanor 25 mg BID', 'description': 'Patients will be randomized to receive 25 mg tenapanor twice daily.', 'interventionNames': ['Drug: Tenapanor 25 mg BID']}, {'type': 'EXPERIMENTAL', 'label': 'Tenapanor 50 mg BID', 'description': 'Patients will be randomized to receive 50 mg tenapanor twice daily.', 'interventionNames': ['Drug: Tenapanor 50 mg BID']}, {'type': 'PLACEBO_COMPARATOR', 'label': 'Placebo Comparator', 'description': 'Patients will be randomized to receive matching placebo twice daily.', 'interventionNames': ['Drug: Placebo']}], 'interventions': [{'name': 'Tenapanor 5 mg BID', 'type': 'DRUG', 'description': 'Patients will receive tenapanor 5 mg BID (total of 10 mg daily)', 'armGroupLabels': ['Tenapanor 5 mg BID']}, {'name': 'Tenapanor 25 mg BID', 'type': 'DRUG', 'description': 'Patients will receive tenapanor 25 mg BID (total of 50 mg daily)', 'armGroupLabels': ['Tenapanor 25 mg BID']}, {'name': 'Tenapanor 50 mg BID', 'type': 'DRUG', 'description': 'Patients will receive tenapanor 50 mg BID (total of 100 mg daily)', 'armGroupLabels': ['Tenapanor 50 mg BID']}, {'name': 'Placebo', 'type': 'DRUG', 'description': 'Patients will receive matching placebo BID', 'armGroupLabels': ['Placebo Comparator']}]}, 'contactsLocationsModule': {'locations': [{'zip': '85225', 'city': 'Chandler', 'state': 'Arizona', 'status': 'RECRUITING', 'country': 'United States', 'contacts': [{'name': 'Reichard Ruiz', 'role': 'CONTACT', 'email': 'rruiz@azclinicaltrials.com'}, {'name': 'Anita Kohli, MD', 'role': 'PRINCIPAL_INVESTIGATOR'}], 'facility': 'Arizona Liver Health - Chandler', 'geoPoint': {'lat': 33.30616, 'lon': -111.84125}}, {'zip': '85018', 'city': 'Phoenix', 'state': 'Arizona', 'status': 'RECRUITING', 'country': 'United States', 'contacts': [{'name': 'Evette San Miguel', 'role': 'CONTACT', 'email': 'Evette@eliteclinicalstudies.com', 'phone': '602-788-3437'}, {'name': 'Joseph Lillo, MD', 'role': 'PRINCIPAL_INVESTIGATOR'}], 'facility': 'Elite Clinical Studies', 'geoPoint': {'lat': 33.44838, 'lon': -112.07404}}, {'zip': '72117', 'city': 'North Little Rock', 'state': 'Arkansas', 'status': 'RECRUITING', 'country': 'United States', 'contacts': [{'name': 'Courtney Voss', 'role': 'CONTACT', 'email': 'courtney@arkgi.net', 'phone': '501-945-9300'}, {'name': 'Johnathan Goodwin, MD', 'role': 'PRINCIPAL_INVESTIGATOR'}], 'facility': 'Arkansas Gastroenterology - North Little Rock', 'geoPoint': {'lat': 34.76954, 'lon': -92.26709}}, {'zip': '91303', 'city': 'Canoga Park', 'state': 'California', 'status': 'RECRUITING', 'country': 'United States', 'contacts': [{'name': 'Anitha Roobalingam', 'role': 'CONTACT', 'email': 'aroobalingam@hopeclinical.com'}, {'name': 'Hessam Aazami, MD', 'role': 'PRINCIPAL_INVESTIGATOR'}], 'facility': 'Hope Clinical Research - Canoga Park', 'geoPoint': {'lat': 34.20112, 'lon': -118.59814}}, {'zip': '91010', 'city': 'Chula Vista', 'state': 'California', 'status': 'RECRUITING', 'country': 'United States', 'contacts': [{'name': 'Jason Colia', 'role': 'CONTACT', 'email': 'jcolia@gwresearch.net', 'phone': '619-585-8882'}, {'name': 'Patrick H Sweet, MD', 'role': 'PRINCIPAL_INVESTIGATOR'}], 'facility': 'GW Research Inc.', 'geoPoint': {'lat': 32.64005, 'lon': -117.0842}}, {'zip': '91910', 'city': 'Chula Vista', 'state': 'California', 'status': 'RECRUITING', 'country': 'United States', 'contacts': [{'name': 'Marilyn Rodriguez', 'role': 'CONTACT', 'email': 'marilyn@gastrosb.com', 'phone': '619-382-3315'}, {'name': 'Erick Alayo, MD', 'role': 'PRINCIPAL_INVESTIGATOR'}], 'facility': 'Erick H. Alayo Medical Corporation', 'geoPoint': {'lat': 32.64005, 'lon': -117.0842}}, {'zip': '90301', 'city': 'Inglewood', 'state': 'California', 'status': 'RECRUITING', 'country': 'United States', 'contacts': [{'name': 'Indira Mohabir', 'role': 'CONTACT', 'email': 'imohabir@allianceclinicalnetwork.com', 'phone': '310-878-2636', 'phoneExt': '1706'}, {'name': 'Soheil Hekmat, MD', 'role': 'PRINCIPAL_INVESTIGATOR'}], 'facility': '310 Clinical Research', 'geoPoint': {'lat': 33.96168, 'lon': -118.35313}}, {'zip': '93534', 'city': 'Lancaster', 'state': 'California', 'status': 'RECRUITING', 'country': 'United States', 'contacts': [{'name': 'Guadalupe Barragan', 'role': 'CONTACT', 'email': 'gbarragan@omclinicaltrials.com'}, {'name': 'Jatinder Pruthi, MD', 'role': 'PRINCIPAL_INVESTIGATOR'}], 'facility': 'Om Research LLC', 'geoPoint': {'lat': 34.69804, 'lon': -118.13674}}, {'zip': '95648', 'city': 'Lincoln', 'state': 'California', 'status': 'RECRUITING', 'country': 'United States', 'contacts': [{'name': 'Leesa Koskela', 'role': 'CONTACT', 'email': 'leesa@ctrsites.com', 'phone': '916-434-8230'}, {'name': 'Jeffrey D Wayne, MD', 'role': 'PRINCIPAL_INVESTIGATOR'}], 'facility': 'Clinical Trials Research', 'geoPoint': {'lat': 38.89156, 'lon': -121.29301}}, {'zip': '92703', 'city': 'Santa Ana', 'state': 'California', 'status': 'RECRUITING', 'country': 'United States', 'contacts': [{'name': 'Thy Tran', 'role': 'CONTACT', 'email': 'Thy.Tran@prxclinical.com'}, {'name': 'Long Dang, MD', 'role': 'PRINCIPAL_INVESTIGATOR'}], 'facility': 'Paragon Rx Clinical, Inc. - Santa Ana', 'geoPoint': {'lat': 33.74557, 'lon': -117.86783}}, {'zip': '80228', 'city': 'Lakewood', 'state': 'Colorado', 'status': 'RECRUITING', 'country': 'United States', 'contacts': [{'name': 'Emily Hager', 'role': 'CONTACT', 'email': 'rmg@jointopo.com', 'phone': '303-722-8987'}, {'name': 'Andrew Korson, MD', 'role': 'PRINCIPAL_INVESTIGATOR'}], 'facility': 'Rocky Mountain Gastroenterology (RMG) - Littleton', 'geoPoint': {'lat': 39.70471, 'lon': -105.08137}}, {'zip': '33308', 'city': 'Fort Lauderdale', 'state': 'Florida', 'status': 'RECRUITING', 'country': 'United States', 'contacts': [{'name': 'Naila Pelegrin', 'role': 'CONTACT', 'email': 'npelegrin@proactivecr.com', 'phone': '954-938-2843'}, {'name': 'David Mishkin, MD', 'role': 'PRINCIPAL_INVESTIGATOR'}], 'facility': 'Proactive Clinical Research', 'geoPoint': {'lat': 26.12231, 'lon': -80.14338}}, {'zip': '33174', 'city': 'Miami', 'state': 'Florida', 'status': 'RECRUITING', 'country': 'United States', 'contacts': [{'name': 'Yamie Chaviano', 'role': 'CONTACT', 'email': 'ychaviano@valenciamedresearch.com'}, {'name': 'Inti Fernandez, MD', 'role': 'PRINCIPAL_INVESTIGATOR'}], 'facility': 'Valencia Medical and Research Center', 'geoPoint': {'lat': 25.77427, 'lon': -80.19366}}, {'zip': '33176', 'city': 'Miami', 'state': 'Florida', 'status': 'RECRUITING', 'country': 'United States', 'contacts': [{'name': 'Teresa Valencia', 'role': 'CONTACT', 'email': 'teresa@roviaclinical.com'}, {'name': 'Miguel Rodriguez, MD', 'role': 'PRINCIPAL_INVESTIGATOR'}], 'facility': 'IMIC, Inc', 'geoPoint': {'lat': 25.77427, 'lon': -80.19366}}, {'zip': '34652', 'city': 'New Port Richey', 'state': 'Florida', 'status': 'RECRUITING', 'country': 'United States', 'contacts': [{'name': 'Mark Mason', 'role': 'CONTACT', 'email': 'mmason@suncoastclinicalresearch.com', 'phone': '727-849-4131'}, {'name': 'Cathy Barnes, MD', 'role': 'PRINCIPAL_INVESTIGATOR'}], 'facility': 'Suncoast Clinical Research, Inc. - New Port Richey', 'geoPoint': {'lat': 28.24418, 'lon': -82.71927}}, {'zip': '34761', 'city': 'Ocoee', 'state': 'Florida', 'status': 'RECRUITING', 'country': 'United States', 'contacts': [{'name': 'Jenny Kuerth', 'role': 'CONTACT', 'email': 'jkuerth@sensiblehealthcare.net', 'phone': '407-654-2724'}, {'name': 'William (Kelly) Bowman, MD', 'role': 'PRINCIPAL_INVESTIGATOR'}], 'facility': 'Sensible Healthcare, LLC', 'geoPoint': {'lat': 28.56917, 'lon': -81.54396}}, {'zip': '32763', 'city': 'Orange City', 'state': 'Florida', 'status': 'RECRUITING', 'country': 'United States', 'contacts': [{'name': 'Jennifer Pages', 'role': 'CONTACT', 'email': 'jpages@clinmastery.com', 'phone': '305-957-7200'}, {'name': 'Glenda Rosa Gonzalez, MD', 'role': 'PRINCIPAL_INVESTIGATOR'}], 'facility': 'Harmony Clinical Research - Orlando', 'geoPoint': {'lat': 28.94888, 'lon': -81.29867}}, {'zip': '34684', 'city': 'Palm Harbor', 'state': 'Florida', 'status': 'RECRUITING', 'country': 'United States', 'contacts': [{'name': 'Alayna Tiffany', 'role': 'CONTACT', 'email': 'atiffany@suncoastclinicalresearch.com', 'phone': '727-781-3655'}, {'name': 'Gary Goldstein, MD', 'role': 'PRINCIPAL_INVESTIGATOR'}], 'facility': 'Suncoast Clinical Research, Inc. - Palm Harbor', 'geoPoint': {'lat': 28.07807, 'lon': -82.76371}}, {'zip': '33060', 'city': 'Pompano Beach', 'state': 'Florida', 'status': 'RECRUITING', 'country': 'United States', 'contacts': [{'name': 'Zachary Weiss', 'role': 'CONTACT', 'email': 'zachary@floridacrc.com'}, {'name': 'Howard Koch, MD', 'role': 'PRINCIPAL_INVESTIGATOR'}], 'facility': 'Clinical Research Center of Florida', 'geoPoint': {'lat': 26.23786, 'lon': -80.12477}}, {'zip': '30328', 'city': 'Atlanta', 'state': 'Georgia', 'status': 'RECRUITING', 'country': 'United States', 'contacts': [{'name': 'Madeline Mendoza', 'role': 'CONTACT', 'email': 'mmendoza@agilecrt.com'}, {'name': 'Vasundhara Cheekati, MD', 'role': 'PRINCIPAL_INVESTIGATOR'}], 'facility': 'Agile Clinical Research Trials, LLC', 'geoPoint': {'lat': 33.749, 'lon': -84.38798}}, {'zip': '30329', 'city': 'Atlanta', 'state': 'Georgia', 'status': 'RECRUITING', 'country': 'United States', 'contacts': [{'name': 'Maddie LaQua', 'role': 'CONTACT', 'email': 'mlaqua@delricht.com', 'phone': '504-336-2667'}, {'name': 'Robert Springer, MD', 'role': 'PRINCIPAL_INVESTIGATOR'}], 'facility': 'DelRicht Clinical Research - Atlanta', 'geoPoint': {'lat': 33.749, 'lon': -84.38798}}, {'zip': '30060', 'city': 'Marietta', 'state': 'Georgia', 'status': 'RECRUITING', 'country': 'United States', 'contacts': [{'name': 'Octavia Nichols', 'role': 'CONTACT', 'email': 'Onichols@gigeorgia.com', 'phone': '678-819-4237'}, {'name': 'Aasim Sheikh, MD', 'role': 'PRINCIPAL_INVESTIGATOR'}], 'facility': 'Gastrointestinal Specialists of Georgia PC', 'geoPoint': {'lat': 33.9526, 'lon': -84.54993}}, {'zip': '30189', 'city': 'Woodstock', 'state': 'Georgia', 'status': 'RECRUITING', 'country': 'United States', 'contacts': [{'name': 'Shelby Satterwhite', 'role': 'CONTACT', 'email': 'shelby.satterwhite@ngclinicalresearch.com'}, {'name': 'Bram Wieskopf, MD', 'role': 'PRINCIPAL_INVESTIGATOR'}], 'facility': 'North Georgia Clinical Research', 'geoPoint': {'lat': 34.10149, 'lon': -84.51938}}, {'zip': '83221', 'city': 'Blackfoot', 'state': 'Idaho', 'status': 'RECRUITING', 'country': 'United States', 'contacts': [{'name': 'Berta Bates', 'role': 'CONTACT', 'email': 'bbates.ect@gmail.com', 'phone': '208-643-0006'}, {'name': 'Paul Beckett, MD', 'role': 'PRINCIPAL_INVESTIGATOR'}], 'facility': 'Elite Clinical Trials-Idaho', 'geoPoint': {'lat': 43.19047, 'lon': -112.34498}}, {'zip': '60031', 'city': 'Gurnee', 'state': 'Illinois', 'status': 'RECRUITING', 'country': 'United States', 'contacts': [{'name': 'Patrycja Kalwajtys', 'role': 'CONTACT', 'email': 'pkalwajtys@cisresearch.com'}, {'name': 'John Agaiby, MD', 'role': 'PRINCIPAL_INVESTIGATOR'}], 'facility': 'Clinical Investigation Specialists, Inc', 'geoPoint': {'lat': 42.3703, 'lon': -87.90202}}, {'zip': '46202', 'city': 'Indianapolis', 'state': 'Indiana', 'status': 'RECRUITING', 'country': 'United States', 'contacts': [{'name': 'Hailey Hunziker', 'role': 'CONTACT', 'email': 'hhunziker@delricht.com', 'phone': '504-336-2667'}, {'name': 'Rachael Holliday, MD', 'role': 'PRINCIPAL_INVESTIGATOR'}], 'facility': 'DelRicht Clinical Research - Indianapolis', 'geoPoint': {'lat': 39.76838, 'lon': -86.15804}}, {'zip': '66209', 'city': 'Overland Park', 'state': 'Kansas', 'status': 'RECRUITING', 'country': 'United States', 'contacts': [{'name': 'Anthony Alioto', 'role': 'CONTACT', 'email': 'aalioto@delricht.com', 'phone': '913-391-7188'}, {'name': 'Jonathan Jacobs', 'role': 'PRINCIPAL_INVESTIGATOR'}], 'facility': 'DelRicht Clinical Research - Overland Park', 'geoPoint': {'lat': 38.98223, 'lon': -94.67079}}, {'zip': '40205', 'city': 'Louisville', 'state': 'Kentucky', 'status': 'RECRUITING', 'country': 'United States', 'contacts': [{'name': 'Jessi Walker', 'role': 'CONTACT', 'email': 'jwalker@delricht.com'}, {'name': 'Michael Lovelace, MD', 'role': 'PRINCIPAL_INVESTIGATOR'}], 'facility': 'DelRicht Clinical Research - Louisville', 'geoPoint': {'lat': 38.25424, 'lon': -85.75941}}, {'zip': '70363', 'city': 'Houma', 'state': 'Louisiana', 'status': 'RECRUITING', 'country': 'United States', 'contacts': [{'name': 'Jahel Osornio', 'role': 'CONTACT', 'email': 'josornio@tandemclinicalresearch.com', 'phone': '985-219-6501'}, {'name': 'Conar Fitton, MD', 'role': 'PRINCIPAL_INVESTIGATOR'}], 'facility': 'Tandem Clinical Research GI - 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