Ignite Creation Date:
2026-03-26 @ 3:17 PM
Ignite Modification Date:
2026-03-29 @ 11:26 PM
Study NCT ID:
NCT07334756
Status:
RECRUITING
Last Update Posted:
2026-01-12
First Post:
2025-12-31
Is NOT Gene Therapy:
True
Has Adverse Events:
False
Brief Title:
Non-Thrust Lumbar and Sacral Mobilizations in Mechanical Low Back Pain
Sponsor:
Organization:
Raw JSON
{'hasResults': False, 'derivedSection': {'miscInfoModule': {'versionHolder': '2026-03-25'}, 'conditionBrowseModule': {'meshes': [{'id': 'D017116', 'term': 'Low Back Pain'}], 'ancestors': [{'id': 'D001416', 'term': 'Back Pain'}, {'id': 'D010146', 'term': 'Pain'}, {'id': 'D009461', 'term': 'Neurologic Manifestations'}, {'id': 'D012816', 'term': 'Signs and Symptoms'}, {'id': 'D013568', 'term': 'Pathological Conditions, Signs and Symptoms'}]}}, 'protocolSection': {'designModule': {'phases': ['NA'], 'studyType': 'INTERVENTIONAL', 'designInfo': {'allocation': 'RANDOMIZED', 'maskingInfo': {'masking': 'SINGLE', 'whoMasked': ['PARTICIPANT'], 'maskingDescription': 'Participant will be blinded about the group allocation'}, 'primaryPurpose': 'TREATMENT', 'interventionModel': 'PARALLEL'}, 'enrollmentInfo': {'type': 'ESTIMATED', 'count': 40}}, 'statusModule': {'overallStatus': 'RECRUITING', 'startDateStruct': {'date': '2025-01-15', 'type': 'ACTUAL'}, 'expandedAccessInfo': {'hasExpandedAccess': False}, 'statusVerifiedDate': '2025-12', 'completionDateStruct': {'date': '2026-01-15', 'type': 'ESTIMATED'}, 'lastUpdateSubmitDate': '2025-12-31', 'studyFirstSubmitDate': '2025-12-31', 'studyFirstSubmitQcDate': '2025-12-31', 'lastUpdatePostDateStruct': {'date': '2026-01-12', 'type': 'ACTUAL'}, 'studyFirstPostDateStruct': {'date': '2026-01-12', 'type': 'ACTUAL'}, 'primaryCompletionDateStruct': {'date': '2025-12-31', 'type': 'ESTIMATED'}}, 'outcomesModule': {'primaryOutcomes': [{'measure': 'Pain intensity', 'timeFrame': '2 weeks', 'description': 'Numeric pain scale rating (NPRS) w3ill be used and It ranges from 0 to 10, 0 means no pain and 10 means worst pain.'}, {'measure': 'Lumbar Range of Motion', 'timeFrame': '2 weeks', 'description': 'It will be measured by Inclinometer . it is Measured by placing the inclinometers at T12 and S1.'}, {'measure': 'Functional Disability', 'timeFrame': '2 weeks', 'description': 'It will be measured by Oswestry Disability Index. It is a 10 items questionnaire used to assess the degree of disability in individuals with low back pain.'}, {'measure': 'Lumbar Proprioception', 'timeFrame': '2 weeks', 'description': 'it is measured by Joint position sense/ error test . it is Measured by placing the inclinometers at T12 and S1.'}]}, 'oversightModule': {'oversightHasDmc': False, 'isFdaRegulatedDrug': False, 'isFdaRegulatedDevice': False}, 'conditionsModule': {'conditions': ['Mechanical Low Back Pain']}, 'descriptionModule': {'briefSummary': 'This study is a randomized controlled trial and the purpose of this study is to determined the effects of sacral mobilizations along with the lumbar mobilizations in mechanical low back pain on components such as pain , lumbar range of motion, lumbar proprioception and functional disability.', 'detailedDescription': 'This study is based on the concept the sacral hypomobility can cause low back pain. Sacral and lumbar mobilizations both improve low back pain.'}, 'eligibilityModule': {'sex': 'ALL', 'stdAges': ['ADULT'], 'maximumAge': '45 Years', 'minimumAge': '18 Years', 'healthyVolunteers': False, 'eligibilityCriteria': '* Inclusion Criteria Adults 18 to 45 years Both genders Low back (from T12 to buttock line) pain for more than 3 months The CMLBP is the chief complaint without leg pain.\n* Exclusion Criteria Acute flare Low Back Pain Thoracic pain Trauma to the spine causing fracture and disruption of the ligaments Leg symptoms when walk, eased in flexion (Signs of stenosis) Paresthesia/numbness Structural deformity (scoliosis, spondylosis, spondylolisthesis) Curve reversal Pregnancy Post-surgery (within 6 months of abdominal or spinal/lower limb surgery) Degenerative and inflammatory spinal diseases Malignancy Centralization and peripheralization'}, 'identificationModule': {'nctId': 'NCT07334756', 'briefTitle': 'Non-Thrust Lumbar and Sacral Mobilizations in Mechanical Low Back Pain', 'organization': {'class': 'OTHER', 'fullName': 'Foundation University Islamabad'}, 'officialTitle': 'Non-Thrust Lumbar and Sacral Mobilizations in Mechanical Low Back Pain', 'orgStudyIdInfo': {'id': 'FUI/CTR/2025/27'}}, 'armsInterventionsModule': {'armGroups': [{'type': 'ACTIVE_COMPARATOR', 'label': 'Group A: lumbar mobilization', 'description': 'Lumbar mobilizations along with the standard therapeutic exercise protocol.', 'interventionNames': ['Procedure: Lumbar Mobilizations']}, {'type': 'EXPERIMENTAL', 'label': 'Group B: Sacral mobilizations+lumbar mobilization', 'description': 'Sacral mobilizations in addition to the lumbar mobilization and therapeutic exercise.', 'interventionNames': ['Procedure: Lumbar and sacral mobilizations']}], 'interventions': [{'name': 'Lumbar Mobilizations', 'type': 'PROCEDURE', 'description': 'Lumbar mobilization protocol:\n\nGrade II or III lumbar stretch mobilization on lumbar hypomobile segments.\n\nTherapeutic exercise protocol:\n\nTherapeutic exercise protocol include warmup, strengthening and cool down phase.', 'armGroupLabels': ['Group A: lumbar mobilization']}, {'name': 'Lumbar and sacral mobilizations', 'type': 'PROCEDURE', 'description': 'Lumbar mobilization protocol:\n\nGrade II or III lumbar stretch mobilization on lumbar hypomobile segments.\n\nSacral Mobilization protocol:\n\nGrade II or III sacral mobilization as sacral stretch mobilizations.\n\nTherapeutic exercise protocol:\n\nTherapeutic exercise protocol include warmup, strengthening and cool down phase.', 'armGroupLabels': ['Group B: Sacral mobilizations+lumbar mobilization']}]}, 'contactsLocationsModule': {'locations': [{'zip': '46000', 'city': 'Islamabad', 'state': 'Punjab Province', 'status': 'RECRUITING', 'country': 'Pakistan', 'contacts': [{'name': 'Qurat ul ain Sara Ahmed, DPT', 'role': 'CONTACT', 'email': 'quratulainsaraahmed@gmail.com', 'phone': '03351182403'}], 'facility': 'Foundation University Islamabad', 'geoPoint': {'lat': 29.7426, 'lon': 73.14353}}], 'centralContacts': [{'name': 'Qurat ul ain Sara Ahmed, DPT', 'role': 'CONTACT', 'email': 'quratulainsaraahmed@gmail.com', 'phone': '03351182403'}, {'name': 'Qurat ul ain Saeed, MS-OMPT', 'role': 'CONTACT', 'email': 'quratulain.saeed@fui.edu.pk', 'phone': '03315562889'}]}, 'sponsorCollaboratorsModule': {'leadSponsor': {'name': 'Foundation University Islamabad', 'class': 'OTHER'}, 'responsibleParty': {'type': 'SPONSOR'}}}}