Ignite Creation Date:
2026-03-26 @ 3:16 PM
Ignite Modification Date:
2026-03-30 @ 2:33 AM
Study NCT ID:
NCT07334457
Status:
RECRUITING
Last Update Posted:
2026-01-12
First Post:
2025-12-30
Is NOT Gene Therapy:
True
Has Adverse Events:
False
Brief Title:
Study of Platelet Population Changes Under Circulatory Support With ECMO
Sponsor:
Organization:
Raw JSON
{'hasResults': False, 'derivedSection': {'miscInfoModule': {'versionHolder': '2026-03-25'}, 'conditionBrowseModule': {'meshes': [{'id': 'D006333', 'term': 'Heart Failure'}, {'id': 'D012131', 'term': 'Respiratory Insufficiency'}], 'ancestors': [{'id': 'D006331', 'term': 'Heart Diseases'}, {'id': 'D002318', 'term': 'Cardiovascular Diseases'}, {'id': 'D012120', 'term': 'Respiration Disorders'}, {'id': 'D012140', 'term': 'Respiratory Tract Diseases'}]}}, 'protocolSection': {'designModule': {'studyType': 'OBSERVATIONAL', 'designInfo': {'timePerspective': 'RETROSPECTIVE', 'observationalModel': 'CASE_ONLY'}, 'enrollmentInfo': {'type': 'ESTIMATED', 'count': 75}, 'patientRegistry': False}, 'statusModule': {'overallStatus': 'RECRUITING', 'startDateStruct': {'date': '2025-03-11', 'type': 'ACTUAL'}, 'expandedAccessInfo': {'hasExpandedAccess': False}, 'statusVerifiedDate': '2025-12', 'completionDateStruct': {'date': '2027-03-11', 'type': 'ESTIMATED'}, 'lastUpdateSubmitDate': '2025-12-30', 'studyFirstSubmitDate': '2025-12-30', 'studyFirstSubmitQcDate': '2025-12-30', 'lastUpdatePostDateStruct': {'date': '2026-01-12', 'type': 'ACTUAL'}, 'studyFirstPostDateStruct': {'date': '2026-01-12', 'type': 'ACTUAL'}, 'primaryCompletionDateStruct': {'date': '2027-03', 'type': 'ESTIMATED'}}, 'outcomesModule': {'primaryOutcomes': [{'measure': 'Proportional Changes in the Different Platelet Populations (native, proaggregating, procoagulant, or apoptotic)', 'timeFrame': 'Days 1, 3, and 7 after the initiation of ECMO treatment.', 'description': 'Proportional Changes in the Different Platelet Populations (native, proaggregating, procoagulant, or apoptotic) on Days 1, 3, and 7 after the initiation of ECMO treatment.'}]}, 'oversightModule': {'oversightHasDmc': False, 'isFdaRegulatedDrug': False, 'isFdaRegulatedDevice': False}, 'conditionsModule': {'keywords': ['Cardiac Failure', 'Respiratory Failure'], 'conditions': ['Cardiac Failure', 'Respiratory Failure']}, 'descriptionModule': {'briefSummary': 'Advances in flow cytometry techniques have led to a better understanding of platelet phenotypes and have revealed the existence of four major platelet populations with distinct functional properties (native, proaggregating, procoagulating, or apoptotic). These phenotypes have a significant impact on the hemostatic capacity of blood platelets, and a proportional change in these populations during ECMO treatment could, at least in part, contribute to the observed complications.'}, 'eligibilityModule': {'sex': 'ALL', 'stdAges': ['ADULT', 'OLDER_ADULT'], 'minimumAge': '18 Years', 'samplingMethod': 'NON_PROBABILITY_SAMPLE', 'studyPopulation': '\\- Adult patient (≥18 years) treated in one of the intensive care units of the Anesthesia and Intensive Care Department at Strasbourg University Hospital and implanted with veno-arterial or veno-venous ECMO within the previous 24 hours.', 'eligibilityCriteria': 'Inclusion Criteria:\n\n* Adult patient (≥18 years) treated in one of the intensive care units of the Anesthesia and Intensive Care Department at Strasbourg University Hospital.\n* Implanted with veno-arterial or veno-venous ECMO within the previous 24 hours.\n\nExclusion Criteria:\n\n* Subject who has expressed their opposition to participating in the study.\n* Subject under legal protection.\n* Subject under guardianship or curatorship.'}, 'identificationModule': {'nctId': 'NCT07334457', 'acronym': 'ECMO-POP', 'briefTitle': 'Study of Platelet Population Changes Under Circulatory Support With ECMO', 'organization': {'class': 'OTHER', 'fullName': 'University Hospital, Strasbourg, France'}, 'officialTitle': 'Study of Platelet Population Changes Under Circulatory Support With ECMO', 'orgStudyIdInfo': {'id': '9614'}}, 'contactsLocationsModule': {'locations': [{'zip': '67091', 'city': 'Strasbourg', 'status': 'RECRUITING', 'country': 'France', 'contacts': [{'name': 'Charles TACQUARD, MD, PhD', 'role': 'CONTACT', 'email': 'charlesambroise.tacquard@chru-strasbourg.fr', 'phone': '33.3.69.55.16.08'}, {'name': 'Charles TACQUARD, MD, PhD', 'role': 'PRINCIPAL_INVESTIGATOR'}, {'name': 'Marie MULLER, MD', 'role': 'SUB_INVESTIGATOR'}, {'name': 'Thomas RESCHWEIN, MD', 'role': 'SUB_INVESTIGATOR'}, {'name': 'Walid OULEHRI, MD', 'role': 'SUB_INVESTIGATOR'}, {'name': 'Laurent SATTLER, MD', 'role': 'SUB_INVESTIGATOR'}, {'name': 'Béatrice HECHLER, Statistician', 'role': 'SUB_INVESTIGATOR'}], 'facility': "Service d'anesthésie-réanimation - CHU de Strasbourg - France", 'geoPoint': {'lat': 48.58392, 'lon': 7.74553}}], 'centralContacts': [{'name': 'Charles TACQUARD, MD, PhD', 'role': 'CONTACT', 'email': 'charlesambroise.tacquard@chru-strasbourg.fr', 'phone': '33.3.69.55.16.08'}]}, 'sponsorCollaboratorsModule': {'leadSponsor': {'name': 'University Hospital, Strasbourg, France', 'class': 'OTHER'}, 'responsibleParty': {'type': 'SPONSOR'}}}}