Ignite Creation Date:
2026-03-26 @ 3:16 PM
Ignite Modification Date:
2026-03-30 @ 8:54 PM
Study NCT ID:
NCT07438457
Status:
COMPLETED
Last Update Posted:
2026-02-27
First Post:
2026-02-23
Is NOT Gene Therapy:
True
Has Adverse Events:
False
Brief Title:
McKenzie and William Exercises in Patients With Sacroiliac Joint Dysfunction
Sponsor:
Organization:
Raw JSON
{'hasResults': False, 'derivedSection': {'miscInfoModule': {'versionHolder': '2026-03-25'}}, 'protocolSection': {'designModule': {'phases': ['NA'], 'studyType': 'INTERVENTIONAL', 'designInfo': {'allocation': 'RANDOMIZED', 'maskingInfo': {'masking': 'SINGLE', 'whoMasked': ['OUTCOMES_ASSESSOR']}, 'primaryPurpose': 'TREATMENT', 'interventionModel': 'PARALLEL'}, 'enrollmentInfo': {'type': 'ACTUAL', 'count': 62}}, 'statusModule': {'overallStatus': 'COMPLETED', 'startDateStruct': {'date': '2025-06-01', 'type': 'ACTUAL'}, 'expandedAccessInfo': {'hasExpandedAccess': False}, 'statusVerifiedDate': '2026-02', 'completionDateStruct': {'date': '2025-11-30', 'type': 'ACTUAL'}, 'lastUpdateSubmitDate': '2026-02-23', 'studyFirstSubmitDate': '2026-02-23', 'studyFirstSubmitQcDate': '2026-02-23', 'lastUpdatePostDateStruct': {'date': '2026-02-27', 'type': 'ACTUAL'}, 'studyFirstPostDateStruct': {'date': '2026-02-27', 'type': 'ACTUAL'}, 'primaryCompletionDateStruct': {'date': '2025-11-30', 'type': 'ACTUAL'}}, 'outcomesModule': {'primaryOutcomes': [{'measure': 'Numeric Pain Rating Scale (NPRS)', 'timeFrame': 'From enrollment to the end of treatment at 8 weeks.', 'description': 'NPRS is a simple tool which is used to assess intensity of pain. Patients have to rate their pain level on NPRS scale from 0 to 10. It provides a quick, quantifiable measure of pain, aiding healthcare providers in monitoring treatment efficacy and adjusting interventions accordingly.'}, {'measure': 'Oswestry Disability Index (ODI)', 'timeFrame': 'From enrollment to the end of treatment at 8 weeks.', 'description': 'ODI is a widely known as questionnaire designed to measure the level of disability in patients with lower back pain. Comprising 10 sections, each focusing on daily activities such as pain intensity, personal care, lifting, walking, sitting, standing, sleeping, social life, traveling, and employment, the ODI assesses the impact of pain on functional abilities. Each section is scored from 0 to 5, with higher scores indicating greater disability. Summing the scores provides a percentage-based measure of disability, ranging from minimal to severe. The ODI is instrumental in clinical practice for evaluating treatment effectiveness and monitoring patient progress over time.'}, {'measure': 'Short form-36 for Quality of Life (SF-36)', 'timeFrame': 'From enrollment to the end of treatment at 8 weeks.', 'description': "SF-36 is a 36-question survey that looks at health-related quality of life in eight areas: physical functioning, role limitations due to physical and mental health, pain in the body, general health perceptions, vitality, social functioning, health. SF-36 is a common tool used in research and clinical settings to measure how diseases affect people, how treatments help people, and how well people are overall. It shows many different aspects of a patient's quality of life. Get a clear picture of both your physical and mental health by scoring each domain. This is useful for both initial tests and keeping an eye on changes in health over time."}]}, 'oversightModule': {'oversightHasDmc': False, 'isFdaRegulatedDrug': False, 'isFdaRegulatedDevice': False}, 'conditionsModule': {'keywords': ['Core stability', 'Disability', 'McKenzie exercises', 'Mulligan mobilization', 'William exercises'], 'conditions': ['Sacroiliac Joint Dysfunction']}, 'referencesModule': {'references': [{'pmid': '31092126', 'type': 'BACKGROUND', 'citation': 'Hides JA, Donelson R, Lee D, Prather H, Sahrmann SA, Hodges PW. Convergence and Divergence of Exercise-Based Approaches That Incorporate Motor Control for the Management of Low Back Pain. J Orthop Sports Phys Ther. 2019 Jun;49(6):437-452. doi: 10.2519/jospt.2019.8451. Epub 2019 May 15.'}, {'pmid': '32247262', 'type': 'BACKGROUND', 'citation': 'Weerasekara I, Deam H, Bamborough N, Brown S, Donnelly J, Thorp N, Rivett DA. Effect of Mobilisation with Movement (MWM) on clinical outcomes in lateral ankle sprains: A systematic review and meta-analysis. Foot (Edinb). 2020 Jun;43:101657. doi: 10.1016/j.foot.2019.101657. Epub 2019 Nov 28.'}, {'pmid': '30154609', 'type': 'BACKGROUND', 'citation': 'Kim J, Kim S, Shim J, Kim H, Moon S, Lee N, Lee M, Jin E, Choi E. Effects of McKenzie exercise, Kinesio taping, and myofascial release on the forward head posture. J Phys Ther Sci. 2018 Aug;30(8):1103-1107. doi: 10.1589/jpts.30.1103. Epub 2018 Aug 7.'}, {'pmid': '31417227', 'type': 'BACKGROUND', 'citation': 'Alhakami AM, Davis S, Qasheesh M, Shaphe A, Chahal A. Effects of McKenzie and stabilization exercises in reducing pain intensity and functional disability in individuals with nonspecific chronic low back pain: a systematic review. J Phys Ther Sci. 2019 Jul;31(7):590-597. doi: 10.1589/jpts.31.590. Epub 2019 Jul 9.'}, {'pmid': '39383118', 'type': 'BACKGROUND', 'citation': 'Hennemann V, Ziegelmann PK, Marcolino MAZ, Duncan BB. The McKenzie Method delivered by credentialed therapists for chronic low back pain with directional preference: systematic review with meta-analysis. J Man Manip Ther. 2025 Apr;33(2):96-111. doi: 10.1080/10669817.2024.2408084. Epub 2024 Oct 9.'}, {'pmid': '38699145', 'type': 'BACKGROUND', 'citation': "Yan H, Zhao P, Guo X, Zhou X. The effects of Core Stability Exercises and Mulligan's mobilization with movement techniques on sacroiliac joint dysfunction. Front Physiol. 2024 Apr 18;15:1337754. doi: 10.3389/fphys.2024.1337754. eCollection 2024."}]}, 'descriptionModule': {'briefSummary': 'The study was conducted to compare the effects of McKenzie Exercises with William exercises for pain, disability and quality of life in patients with sacroiliac joint pain'}, 'eligibilityModule': {'sex': 'ALL', 'stdAges': ['ADULT'], 'maximumAge': '50 Years', 'minimumAge': '20 Years', 'healthyVolunteers': False, 'eligibilityCriteria': 'Inclusion Criteria:\n\n* Both male and female age between 20 and 50 years\n* Patients with sacroiliac joint pain(PSIS) typically present to the buttocks\n* Pain on numeric pain rating scale ranges between 4-8\n* Three out of five tests are positive according to Leslett\'s criteria from following tests; "distraction test", "FABER Test", Compression Test, "Thigh Thrust test","Gaenslen\'s test"\n\nExclusion Criteria:\n\n* Patients with lumber stenosis and radiculopathy was excluded.\n* Patient diagnosed of spondylolisthesis and ankylosing spondylitis was not included in the study.\n* Pregnant and lactating females was excluded\n* Rheumatoid arthritis, hip fractures.\n* History of any prior orthopedic surgery.'}, 'identificationModule': {'nctId': 'NCT07438457', 'briefTitle': 'McKenzie and William Exercises in Patients With Sacroiliac Joint Dysfunction', 'organization': {'class': 'OTHER', 'fullName': 'Riphah International University'}, 'officialTitle': 'Comparative Effects of Mckenzie and William Exercises on Pain, Disability and Quality of Life in Patients With Sacroiliac Joint Dysfunction', 'orgStudyIdInfo': {'id': 'REC/RCR & AHS/24/01111'}}, 'armsInterventionsModule': {'armGroups': [{'type': 'EXPERIMENTAL', 'label': 'McKenzie Therapy', 'interventionNames': ['Other: McKenzie Exercises', 'Other: Conventional Physical Therapy']}, {'type': 'ACTIVE_COMPARATOR', 'label': 'William Exercises', 'interventionNames': ['Other: William Exercises', 'Other: Conventional Physical Therapy']}], 'interventions': [{'name': 'McKenzie Exercises', 'type': 'OTHER', 'description': 'Prone on Elbows: The patient was lie on their stomach with their elbows positioned under the shoulders, allowing them to rest on their forearms. This position hold for 15 seconds, with the patient instructed to take deep breaths and relax. This exercise repeated 10 times to enhance spinal extension and relieve pressure.\n\nProne Press-Ups: In this exercise, the patient was prone line and hands placed under shoulders. They gradually straighten their elbows, lifting the upper body within a pain-free range. Each press-up was held for 15 seconds and repeated 10 times, aiming to promote spinal extension and alleviate pain.\n\nExtension in Standing: The patient was stand in a balanced position and lean backward as far as possible, allowing their head to tip back, then return to a neutral stance. This extension was held for 15 seconds and repeated 10 times, with the goal of improving lumbar mobility and centralizing pain.\n\nThree sessions per week were continued for 8 weeks.', 'armGroupLabels': ['McKenzie Therapy']}, {'name': 'William Exercises', 'type': 'OTHER', 'description': 'William exercises was performed to strengthen up the abdominal and gluteal musculature in an effort to manage the sacroiliac joint pain. In this pelvic tilt exercise, Single knee to Chest exercise, Double knee to Chest exercises and hamstring stretching was performed 3 sets of each exercise with hold for 8 to 10 sec and 10 repetitions each set was performed for three times a week. This was continued for 8 weeks.', 'armGroupLabels': ['William Exercises']}, {'name': 'Conventional Physical Therapy', 'type': 'OTHER', 'description': 'Mulligan Mobilization: For Mulligan mobilization, the patient assumed a prone position. A posterior-to-anterior glide was applied to the sacroiliac joint in three sets of 10 repetitions. The patient was instructed to extend the leg simultaneously with the glide, helping to realign the joint and reduce discomfort by promoting proper joint movement.\n\nHot Therapy: Heat therapy was administered to the lower back and sacroiliac joint (SIJ) area for 10 minutes to improve blood flow, reduce stiffness, and prepare tissues for further interventions.\n\nTranscutaneous Electrical Nerve Stimulation (TENS): TENS was applied as an analgesic modality. In the prone position, the patient underwent TENS therapy for 20 minutes at a frequency of 20-50 Hz. Two electrodes placed on the primary painful area, while the other two was be positioned along the path of the radiating nerve to help reduce pain and promote muscle relaxation.', 'armGroupLabels': ['McKenzie Therapy', 'William Exercises']}]}, 'contactsLocationsModule': {'locations': [{'zip': '54000', 'city': 'Lahore', 'state': 'Punjab Province', 'country': 'Pakistan', 'facility': 'Fatima Memorial Hospital', 'geoPoint': {'lat': 31.558, 'lon': 74.35071}}], 'overallOfficials': [{'name': 'Humera Mubashar, MS-OMPT', 'role': 'PRINCIPAL_INVESTIGATOR', 'affiliation': 'Riphah International University'}]}, 'ipdSharingStatementModule': {'ipdSharing': 'NO'}, 'sponsorCollaboratorsModule': {'leadSponsor': {'name': 'Riphah International University', 'class': 'OTHER'}, 'responsibleParty': {'type': 'SPONSOR'}}}}