Ignite Creation Date:
2026-03-26 @ 3:14 PM
Ignite Modification Date:
2026-04-08 @ 11:35 PM
Study NCT ID:
NCT07339995
Status:
NOT_YET_RECRUITING
Last Update Posted:
2026-01-14
First Post:
2026-01-06
Is NOT Gene Therapy:
True
Has Adverse Events:
False
Brief Title:
Fertility Outcomes of Ovarian Tissue Cryopreservation
Sponsor:
Organization:
Raw JSON
{'hasResults': False, 'derivedSection': {'miscInfoModule': {'versionHolder': '2026-03-25'}, 'conditionBrowseModule': {'meshes': [{'id': 'D009369', 'term': 'Neoplasms'}]}}, 'protocolSection': {'designModule': {'studyType': 'OBSERVATIONAL', 'designInfo': {'timePerspective': 'PROSPECTIVE', 'observationalModel': 'COHORT'}, 'enrollmentInfo': {'type': 'ESTIMATED', 'count': 100}, 'patientRegistry': False}, 'statusModule': {'overallStatus': 'NOT_YET_RECRUITING', 'startDateStruct': {'date': '2026-01-15', 'type': 'ESTIMATED'}, 'expandedAccessInfo': {'hasExpandedAccess': False}, 'statusVerifiedDate': '2026-01', 'completionDateStruct': {'date': '2032-01-14', 'type': 'ESTIMATED'}, 'lastUpdateSubmitDate': '2026-01-06', 'studyFirstSubmitDate': '2026-01-06', 'studyFirstSubmitQcDate': '2026-01-06', 'lastUpdatePostDateStruct': {'date': '2026-01-14', 'type': 'ACTUAL'}, 'studyFirstPostDateStruct': {'date': '2026-01-14', 'type': 'ACTUAL'}, 'primaryCompletionDateStruct': {'date': '2031-01-14', 'type': 'ESTIMATED'}}, 'outcomesModule': {'primaryOutcomes': [{'measure': 'Surgical complications', 'timeFrame': '15 years', 'description': 'Surgical complications after ovarian tissue transplantation'}, {'measure': 'Pregnancy rate', 'timeFrame': '15 years', 'description': 'Pregnancy rate after ovarian tissue transplantation'}]}, 'oversightModule': {'isFdaRegulatedDrug': False, 'isFdaRegulatedDevice': False}, 'conditionsModule': {'conditions': ['Neoplasms']}, 'descriptionModule': {'briefSummary': "With the advancement of assisted reproductive technology, more young cancer patients can consider having children. Ovaries and testes are important reproductive organs, and drugs, diseases, chemotherapy, and radiotherapy can all damage them. Reproductive preservation technology aims to protect patients whose reproductive ability has been damaged due to gonadotoxic drug therapy. Women can preserve their reproductive ability by freezing ovarian tissue cryopreservation so that they can have children in the future. Patients who have undergone or will undergo ovarian tissue cryopreservation in Hong Kong Children's Hospital will be invited to participate in the study. Here, we aim to evaluate the outcomes after ovarian tissue cryopreservation."}, 'eligibilityModule': {'sex': 'FEMALE', 'stdAges': ['CHILD', 'ADULT'], 'maximumAge': '18 Years', 'minimumAge': '0 Years', 'genderBased': True, 'samplingMethod': 'PROBABILITY_SAMPLE', 'studyPopulation': "Patients who have undergone or will undergo ovarian tissue cryopreservation in the Hong Kong Children's Hospital will be invited to join this study.", 'healthyVolunteers': False, 'eligibilityCriteria': "Inclusion Criteria:\n\n* Patients aged from 0-18 years old and diagnosed with cancer\n* Patients who have undergone or will undergo ovarian tissue cryopreservation in Hong Kong Children's Hospital\n* For patients under 18 years old, parents/legal guardians will be asked to further sign the consent for them.\n\nExclusion Criteria:\n\n* Patients unable to provide consent/assent (i.e. significant psychiatric problems/cognitive delay)\n* Male patients"}, 'identificationModule': {'nctId': 'NCT07339995', 'briefTitle': 'Fertility Outcomes of Ovarian Tissue Cryopreservation', 'organization': {'class': 'OTHER', 'fullName': 'Chinese University of Hong Kong'}, 'officialTitle': 'Fertility Outcomes of Ovarian Tissue Cryopreservation', 'orgStudyIdInfo': {'id': 'PAED-2025-067'}}, 'armsInterventionsModule': {'interventions': [{'name': 'Ovarian tissue freezing and subsequent auto-transplantation after thawing', 'type': 'OTHER', 'description': 'Removal of the ovarian tissue will be retrieved via laparoscopic surgery under general anesthesia. The ovarian cortical tissue obtained will be transferred on ice to the laboratory for cryopreservation. After medical treatment, if the patient would like to start a family but has experienced premature ovarian failure, she will have ovarian tissue auto-transplantation after thawing.'}]}, 'contactsLocationsModule': {'centralContacts': [{'name': 'Elaine Ng', 'role': 'CONTACT', 'email': 'elaineng@cuhk.edu.hk', 'phone': '35052745'}], 'overallOfficials': [{'name': 'Pui Wah Jacqueline Chung', 'role': 'PRINCIPAL_INVESTIGATOR', 'affiliation': 'Chinese University of Hong Kong'}]}, 'ipdSharingStatementModule': {'ipdSharing': 'UNDECIDED'}, 'sponsorCollaboratorsModule': {'leadSponsor': {'name': 'Chinese University of Hong Kong', 'class': 'OTHER'}, 'responsibleParty': {'type': 'PRINCIPAL_INVESTIGATOR', 'investigatorTitle': 'Associate Professor', 'investigatorFullName': 'Chung Pui Wah Jacqueline', 'investigatorAffiliation': 'Chinese University of Hong Kong'}}}}