Ignite Creation Date:
2026-03-26 @ 3:14 PM
Ignite Modification Date:
2026-03-26 @ 9:28 PM
Study NCT ID:
NCT07438561
Status:
COMPLETED
Last Update Posted:
2026-02-27
First Post:
2026-02-23
Is Gene Therapy:
True
Has Adverse Events:
False
Brief Title:
Hold-relax and Muscle Energy Techniques in Patients With Post-traumatic Knee Stiffness
Sponsor:
Organization:
Raw JSON
{'hasResults': False, 'derivedSection': {'miscInfoModule': {'versionHolder': '2026-03-25'}, 'conditionBrowseModule': {'meshes': [{'id': 'D009043', 'term': 'Motor Activity'}], 'ancestors': [{'id': 'D001519', 'term': 'Behavior'}]}}, 'protocolSection': {'designModule': {'phases': ['NA'], 'studyType': 'INTERVENTIONAL', 'designInfo': {'allocation': 'RANDOMIZED', 'maskingInfo': {'masking': 'SINGLE', 'whoMasked': ['OUTCOMES_ASSESSOR']}, 'primaryPurpose': 'TREATMENT', 'interventionModel': 'PARALLEL'}, 'enrollmentInfo': {'type': 'ACTUAL', 'count': 68}}, 'statusModule': {'overallStatus': 'COMPLETED', 'startDateStruct': {'date': '2025-01-01', 'type': 'ACTUAL'}, 'expandedAccessInfo': {'hasExpandedAccess': False}, 'statusVerifiedDate': '2026-02', 'completionDateStruct': {'date': '2025-10-31', 'type': 'ACTUAL'}, 'lastUpdateSubmitDate': '2026-02-23', 'studyFirstSubmitDate': '2026-02-23', 'studyFirstSubmitQcDate': '2026-02-23', 'lastUpdatePostDateStruct': {'date': '2026-02-27', 'type': 'ACTUAL'}, 'studyFirstPostDateStruct': {'date': '2026-02-27', 'type': 'ACTUAL'}, 'primaryCompletionDateStruct': {'date': '2025-10-31', 'type': 'ACTUAL'}}, 'outcomesModule': {'primaryOutcomes': [{'measure': 'Numeric Pain Rating Scale (NPRS)', 'timeFrame': 'From enrollment to the end of the treatment at 8 weeks.', 'description': "Numeric Pain Rating Scale is a subjective measure using which patient's rate their pain. It consists of 11 points, having an overall score ranging from 0 to 10, where: 0, 1 - 3, 4 - 6, 7 - 10 represents no pain, mild, moderate and the most severe pain respectively"}, {'measure': 'Universal Goniometer', 'timeFrame': 'From enrollment to the end of the treatment at 8 weeks.', 'description': 'Range of motion of joints are usually assessed by a device known as universal goniometer. meter has two arms stationary as well as movable arm. The Centre of the goniometer is known as fulcrum. Through goniometer in each plane joint ranges are measured.'}, {'measure': 'Lower Extremity Function Scale (LEFS)', 'timeFrame': 'From enrollment to the end of the treatment at 8 weeks.', 'description': 'The Lower Extremity Functional Scale (LEFS) is a 20-item self-report questionnaire assessing functionality in patients with knee and other lower limb disorders. Patients rate their difficulty with activities on a 0-4 scale (0=extreme difficulty/unable, 4=no difficulty), with a total score out of 80; higher scores indicate better function.'}]}, 'oversightModule': {'oversightHasDmc': False, 'isFdaRegulatedDrug': False, 'isFdaRegulatedDevice': False}, 'conditionsModule': {'keywords': ['Knee Stiffness', 'Range of motion', 'exercise', 'exercise therapy', 'muscle energy technique'], 'conditions': ['Knee Discomfort']}, 'referencesModule': {'references': [{'type': 'BACKGROUND', 'citation': 'Moradi MR. The effect of a muscle energy session on increasing knee extension in People with shortness of knee posterior muscles. National University. 2020'}, {'pmid': '41114387', 'type': 'BACKGROUND', 'citation': 'Xu L, Li J, Sheng Q, Wang G. Clinical Application of Muscle Energy Technique for Knee Function Recovery After Total Knee Arthroplasty. J Pain Res. 2025 Oct 14;18:5409-5416. doi: 10.2147/JPR.S537482. eCollection 2025.'}, {'pmid': '27457916', 'type': 'BACKGROUND', 'citation': 'Valenza MC, Torres-Sanchez I, Cabrera-Martos I, Valenza-Demet G, Cano-Cappellacci M. Acute Effects of Contract-Relax Stretching vs. TENS in Young Subjects With Anterior Knee Pain: A Randomized Controlled Trial. J Strength Cond Res. 2016 Aug;30(8):2271-8. doi: 10.1097/JSC.0000000000000215.'}, {'pmid': '37330762', 'type': 'BACKGROUND', 'citation': 'Nazary-Moghadam S, Yahya-Zadeh A, Zare MA, Ali Mohammadi M, Marouzi P, Zeinalzadeh A. Comparison of utilizing modified hold-relax, muscle energy technique, and instrument-assisted soft tissue mobilization on hamstring muscle length in healthy athletes: Randomized controlled trial. J Bodyw Mov Ther. 2023 Jul;35:151-157. doi: 10.1016/j.jbmt.2023.04.079. Epub 2023 Apr 21.'}, {'pmid': '36171728', 'type': 'BACKGROUND', 'citation': 'Bhosale P, Kolke Pt S. Effectiveness of instrument assisted soft tissue mobilization (IASTM) and muscle energy technique (MET) on post-operative elbow stiffness: a randomized clinical trial. J Man Manip Ther. 2023 Oct;31(5):340-348. doi: 10.1080/10669817.2022.2122372. Epub 2022 Sep 28.'}, {'pmid': '29861257', 'type': 'BACKGROUND', 'citation': 'Balasundaram AP, Sreerama Rajan S. Short-term effects of mobilisation with movement in patients with post-traumatic stiffness of the knee joint. J Bodyw Mov Ther. 2018 Apr;22(2):498-501. doi: 10.1016/j.jbmt.2017.06.007. Epub 2017 Jun 15.'}, {'pmid': '38802553', 'type': 'BACKGROUND', 'citation': 'Khan T, Rizvi MR, Sharma A, Ahmad F, Hasan S, Uddin S, Sidiq M, Ammari A, Iqbal A, Alghadir AH. Assessing muscle energy technique and foam roller self-myofascial release for low back pain management in two-wheeler riders. Sci Rep. 2024 May 27;14(1):12144. doi: 10.1038/s41598-024-62881-8.'}]}, 'descriptionModule': {'briefSummary': 'The study was conducted to compare the effects of hold-relax and muscle energy technique on pain, range of motion an lower extremity function in patients with post-traumatic knee stiffness.'}, 'eligibilityModule': {'sex': 'ALL', 'stdAges': ['ADULT'], 'maximumAge': '35 Years', 'minimumAge': '18 Years', 'healthyVolunteers': False, 'eligibilityCriteria': 'Inclusion Criteria:\n\n* Patients who had fracture and treated either with POP or ORIF.\n* Fracture healing completed.\n* Both genders of age between 18-35.\n* Conservative treatment of fracture with POP for minimum 6 weeks.\n* NPRS more than or equal to 2.\n\nExclusion Criteria:\n\n* Pathological fracture.\n* Post-traumatic myositis ossificans.\n* Ligamental or Meniscal tears.\n* Any tumor in the knee region.\n* Osteoarthritis.'}, 'identificationModule': {'nctId': 'NCT07438561', 'briefTitle': 'Hold-relax and Muscle Energy Techniques in Patients With Post-traumatic Knee Stiffness', 'organization': {'class': 'OTHER', 'fullName': 'Riphah International University'}, 'officialTitle': 'Comparative Effects of Hold-relax and Muscle Energy Techniques on Pain, Range of Motion and Lower Extremity Function in Patients With Post-traumatic Knee Stiffness', 'orgStudyIdInfo': {'id': 'REC/RCR & AHS/24/01103'}}, 'armsInterventionsModule': {'armGroups': [{'type': 'EXPERIMENTAL', 'label': 'Hold-Relax Technique', 'interventionNames': ['Other: Hold-Relax Technique', 'Other: Standard Physical Therapy']}, {'type': 'ACTIVE_COMPARATOR', 'label': 'Muscle Energy Technique', 'interventionNames': ['Other: Muscle Energy Technique', 'Other: Standard Physical Therapy']}], 'interventions': [{'name': 'Hold-Relax Technique', 'type': 'OTHER', 'description': 'Hold-Relax: Patient was in prone position, therapist was on the affected site, the affected knee was bent to the available and pain free range at that range therapist applied pressure and held it for 8-10 seconds repeated for 10 times. 3 sessions per week for a total of 8 weeks.', 'armGroupLabels': ['Hold-Relax Technique']}, {'name': 'Muscle Energy Technique', 'type': 'OTHER', 'description': 'Muscle Energy Technique: Patient was in prone position, therapist was on the affected site, the affected knee was bent to the available and pain free range at that range therapist applied pressure and asked the patient to move his knee in extension against the resistance applied by therapist for 10 seconds. And then patient flexed his knee actively and process was repeated for 10 times. 3 sessions per week for a total of 8 weeks.', 'armGroupLabels': ['Muscle Energy Technique']}, {'name': 'Standard Physical Therapy', 'type': 'OTHER', 'description': '* Hot packs were applied to patients for a period of 10 minutes.\n* Mulligan mobilization techniques were performed on the knee joint.\n* Knee isometrics were done.', 'armGroupLabels': ['Hold-Relax Technique', 'Muscle Energy Technique']}]}, 'contactsLocationsModule': {'locations': [{'zip': '54000', 'city': 'Lahore', 'state': 'Punjab Province', 'country': 'Pakistan', 'facility': 'Naseer Hospital', 'geoPoint': {'lat': 31.558, 'lon': 74.35071}}], 'overallOfficials': [{'name': 'Ali Raza, MS-OMPT', 'role': 'PRINCIPAL_INVESTIGATOR', 'affiliation': 'Riphah International University'}]}, 'ipdSharingStatementModule': {'ipdSharing': 'NO'}, 'sponsorCollaboratorsModule': {'leadSponsor': {'name': 'Riphah International University', 'class': 'OTHER'}, 'responsibleParty': {'type': 'SPONSOR'}}}}