Ignite Creation Date:
2025-12-25 @ 5:19 AM
Ignite Modification Date:
2026-03-03 @ 3:09 PM
Study NCT ID:
NCT01523327
Status:
UNKNOWN
Last Update Posted:
2012-02-01
First Post:
2012-01-30
Is NOT Gene Therapy:
True
Has Adverse Events:
False
Brief Title:
Study of Association Between Maternal Uric Acid , Maternal and Fetal Outcome in Pregnant Women With Hypertension
Sponsor:
Organization:
Raw JSON
{'hasResults': False, 'derivedSection': {'miscInfoModule': {'versionHolder': '2025-12-24'}, 'conditionBrowseModule': {'meshes': [{'id': 'D046110', 'term': 'Hypertension, Pregnancy-Induced'}], 'ancestors': [{'id': 'D011248', 'term': 'Pregnancy Complications'}, {'id': 'D005261', 'term': 'Female Urogenital Diseases and Pregnancy Complications'}, {'id': 'D000091642', 'term': 'Urogenital Diseases'}, {'id': 'D006973', 'term': 'Hypertension'}, {'id': 'D014652', 'term': 'Vascular Diseases'}, {'id': 'D002318', 'term': 'Cardiovascular Diseases'}]}}, 'protocolSection': {'designModule': {'studyType': 'OBSERVATIONAL', 'designInfo': {'timePerspective': 'CROSS_SECTIONAL'}, 'enrollmentInfo': {'type': 'ESTIMATED', 'count': 80}}, 'statusModule': {'overallStatus': 'UNKNOWN', 'lastKnownStatus': 'RECRUITING', 'startDateStruct': {'date': '2011-10'}, 'expandedAccessInfo': {'hasExpandedAccess': False}, 'statusVerifiedDate': '2012-01', 'completionDateStruct': {'date': '2012-10', 'type': 'ESTIMATED'}, 'lastUpdateSubmitDate': '2012-01-31', 'studyFirstSubmitDate': '2012-01-30', 'studyFirstSubmitQcDate': '2012-01-31', 'lastUpdatePostDateStruct': {'date': '2012-02-01', 'type': 'ESTIMATED'}, 'studyFirstPostDateStruct': {'date': '2012-02-01', 'type': 'ESTIMATED'}, 'primaryCompletionDateStruct': {'date': '2011-11', 'type': 'ACTUAL'}}, 'oversightModule': {'oversightHasDmc': True}, 'conditionsModule': {'keywords': ['Uric acid'], 'conditions': ['Uric Acid and Hypertension in Pregnancy']}, 'referencesModule': {'references': [{'pmid': '14071979', 'type': 'RESULT', 'citation': 'MATSELIUKH BP. [TRANSMISSION OF CERTAIN BIOCHEMICAL PROPERTIES IN ACTINOMYCETES BY MEANS OF DNA UNDER CONDITIONS OF HETEROTRANSFORMATION]. Mikrobiol Zh. 1963;25:3-6. No abstract available. Russian.'}, {'pmid': '19003642', 'type': 'RESULT', 'citation': 'Paula LG, da Costa BE, Poli-de-Figueiredo CE, Antonello IC. Does uric acid provide information about maternal condition and fetal outcome in pregnant women with hypertension? Hypertens Pregnancy. 2008;27(4):413-20. doi: 10.1080/10641950801955709.'}], 'seeAlsoLinks': [{'url': 'http://www.ncbi.nlm.nih.gov/pubmed?term=does+uric+acid+provide+information+about+maternal+condition+and+fetal+outcome+in+pregnant+women+with+hypertension&TransSchema=title&cmd=detailssearch', 'label': 'does+uric+acid+provide+information+about+maternal+condition+and+fetal+outcome+in+pregnant+women+with+hypertension\\&TransSchema=title\\&cmd=detailssearch'}, {'url': 'http://www.ncbi.nlm.nih.gov/pubmed?', 'label': 'does+uric+acid+provide+information+about+maternal+condition+and+fetal+outcome+in+pregnant+women+with+hypertension\\&TransSchema=title\\&cmd=detailssearch'}]}, 'descriptionModule': {'briefSummary': 'Association of maternal uric acid with maternal condition and fetal outcome in pregnant women with hypertension.', 'detailedDescription': 'Association of maternal uric acid with maternal condition(renal function,liver function,...ect.) and fetal outcome(birth weight,APGER score) in pregnant women with hypertension.'}, 'eligibilityModule': {'sex': 'FEMALE', 'stdAges': ['ADULT'], 'maximumAge': '40 Years', 'minimumAge': '18 Years', 'samplingMethod': 'PROBABILITY_SAMPLE', 'studyPopulation': 'The study will include 80 pregnant ladies with hypertension admitted to the maternity ward of the hospital who will be divided into two groups according to their uric acid level.', 'healthyVolunteers': False, 'eligibilityCriteria': 'Inclusion Criteria:\n\n* Age:18-40 years old\n* Gestational age:28-42 weeks gestation singleton pregnancy of living fetus\n* Non smoker\n\nExclusion Criteria:\n\n* women who refuse the study\n* Any medical or obstetric disorders especially D.M.,renal disease,hepatic, cardiac disorders or gout arthritis, other than hypertension if present.\n* Previously elevated uric acid level.\n* Hemolytic or sickle cell anemia,urinary tract infection.\n* Use of diuretics or anti-inflammatory drugs.'}, 'identificationModule': {'nctId': 'NCT01523327', 'briefTitle': 'Study of Association Between Maternal Uric Acid , Maternal and Fetal Outcome in Pregnant Women With Hypertension', 'organization': {'class': 'OTHER', 'fullName': 'Ain Shams Maternity Hospital'}, 'officialTitle': 'Association of Maternal Uric Acid With Maternal Condition and Fetal Outcome in Pregnant Women With Hypertension', 'orgStudyIdInfo': {'id': 'ainshamsMH'}}, 'armsInterventionsModule': {'armGroups': [{'label': 'A', 'description': '40 pregnant Women with hypertension who have uric acid level more than 6 mg per dL.', 'interventionNames': ['Other: measuring protein creatinin ratio,serum uric acid']}, {'label': 'B', 'description': '40 pregnant women with hypertension who have uric acid level less than 6 mg per dl.', 'interventionNames': ['Other: measuring protein creatinin ratio,serum uric acid']}], 'interventions': [{'name': 'measuring protein creatinin ratio,serum uric acid', 'type': 'OTHER', 'description': 'A non-deproteinized Jaffe reaction is employed to measure creatinine and urinary protein measured by an automated colorimetric assay using pyrogallol red and sodium molybdate.\n\nMeasuring of serum uric acid by(2,4,6-tribromo-3-hydroxybenzoic acid)TBHBA by uricase method.', 'armGroupLabels': ['A', 'B']}]}, 'contactsLocationsModule': {'locations': [{'zip': '11117', 'city': 'Cairo', 'status': 'RECRUITING', 'country': 'Egypt', 'contacts': [{'name': 'nermin marzouk touma, M.B.,B.Ch', 'role': 'PRINCIPAL_INVESTIGATOR'}], 'facility': 'Ain shams maternity hospital', 'geoPoint': {'lat': 30.06263, 'lon': 31.24967}}], 'centralContacts': [{'name': 'Nermin marzouk touma, M.B.,B.Ch', 'role': 'CONTACT', 'email': 'nermindave@gmail.com', 'phone': '01222740182', 'phoneExt': '002'}, {'name': 'nermin Marzouk touma, M.B.,B.Ch', 'role': 'CONTACT', 'email': 'nermindave@gmail.com', 'phone': '0862636607', 'phoneExt': '002'}], 'overallOfficials': [{'name': 'Mohamed Saeedeldin Elsafty, assistant lecture', 'role': 'STUDY_DIRECTOR', 'affiliation': 'Ain Shams Maternity Hospital'}]}, 'sponsorCollaboratorsModule': {'leadSponsor': {'name': 'Ain Shams Maternity Hospital', 'class': 'OTHER'}, 'responsibleParty': {'type': 'PRINCIPAL_INVESTIGATOR', 'investigatorTitle': 'Nermin Marzouk Agaibi', 'investigatorFullName': 'nermin marzouk agaibi', 'investigatorAffiliation': 'Ain Shams Maternity Hospital'}}}}